Jeffrey A Feinstein
Affiliation: Stanford University
- Evaluation, risk stratification, and management of pulmonary hypertension in patients with congenital heart diseaseJeffrey A Feinstein
Stanford University, Palo Alto, CA, USA
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu . 2009..An overview of the evaluation process for this patient population is presented along with a review of evidence for risk stratification and a generalized account of the current state of medical therapy...
- Wall shear stress is decreased in the pulmonary arteries of patients with pulmonary arterial hypertension: An image-based, computational fluid dynamics studyBeverly T Tang
Department of Mechanical Engineering, Stanford University, USA
Pulm Circ 2:470-6. 2012..Reduced WSS in proximal pulmonary arteries may play a role in the pathogenesis and progression of PAH. This data may serve as a basis for future in vitro studies of, for example, effects of WSS on gene expression...
- Hypoplastic left heart syndrome: current considerations and expectationsJeffrey A Feinstein
Department of Pediatrics, Stanford University School of Medicine, Lucile Salter Packard Children s Hospital, Palo Alto, California 94304, USA
J Am Coll Cardiol 59:S1-42. 2012..Issues surrounding the genetics of HLHS, developmental outcomes, and quality of life are addressed in addition to the many other considerations for caring for this group of complex patients...
- Comparison of contrast echocardiography versus cardiac catheterization for detection of pulmonary arteriovenous malformationsJeffrey A Feinstein
Department of Pediatrics, Stanford University, Stanford, California, USA
Am J Cardiol 89:281-5. 2002..Additional studies are needed to follow patients with mildly positive contrast echo studies to enable determination of their clinical relevance...
- Unifocalization of major aortopulmonary collaterals in single-ventricle patientsOlaf Reinhartz
Department of Cardiothoracic Surgery, Division of Pediatric Cardiac Surgery, Stanford University, Stanford, California 94305, USA
Ann Thorac Surg 82:934-8; discussion 938-9. 2006..It is unknown whether their pulmonary vascular bed can be reconstructed and low enough pulmonary vascular resistance achieved to allow for superior or total cavopulmonary connections...
- Perioperative complications in children with pulmonary hypertension undergoing general anesthesia with ketamineGlyn D Williams
Division of Pediatric Cardiology, Department of Anesthesia, Lucile Packard Children s Hospital, Stanford University, Stanford, CA, USA
Paediatr Anaesth 20:28-37. 2010..Uncertainty remains about the safety of ketamine anesthesia in this patient population...
- Three-dimensional hemodynamics in the human pulmonary arteries under resting and exercise conditionsBeverly T Tang
Department of Mechanical Engineering, Stanford University, Stanford, CA 94305 5431, USA
Ann Biomed Eng 39:347-58. 2011..These data indicate the amount of energy dissipation that typically occurs with exercise and may be useful in future surgical planning applications...
- Proximal pulmonary artery blood flow characteristics in healthy subjects measured in an upright posture using MRI: the effects of exercise and ageChristopher P Cheng
Department of Mechanical Engineering, Stanford University, Stanford, California 94305 4038, USA
J Magn Reson Imaging 21:752-8. 2005..To use MRI to quantify blood flow conditions in the proximal pulmonary arteries of healthy children and adults at rest and during exercise in an upright posture...
- Chronic effects of pulmonary artery stenosis on hemodynamic and structural development of the lungsHedi Razavi
Department of Bioengineering, Stanford University, California 94305 5444, USA
Am J Physiol Lung Cell Mol Physiol 304:L17-28. 2013..There are consequences on development of both lungs in the presence of an LPA stenosis at young age. These results suggest that early intervention may be necessary to optimize left lung growth and minimize right lung vascular pathology...
- Percutaneous transluminal coronary angioplasty in a two-month old with coronary stenosis presenting as congenital cardiomyopathy: acute results and intermediate follow-upCheung Wah Boron Cheng
Department of Pediatrics, Stanford University, Stanford, California, USA
Catheter Cardiovasc Interv 68:632-6. 2006..Technical considerations, immediate results, and 3-year follow-up are provided...
- Effects of exercise and respiration on hemodynamic efficiency in CFD simulations of the total cavopulmonary connectionAlison L Marsden
Pediatrics Department, Stanford University, Clark Center E350, Stanford, CA 94305, USA
Ann Biomed Eng 35:250-63. 2007..We propose that respiration and exercise should be incorporated into TCPC CFD simulations to provide increasingly realistic evaluations of TCPC performance...
- Computational fluid dynamic simulations for determination of ventricular workload in aortic arch obstructionsJessica S Coogan
Department of Bioengineering, Stanford University, Stanford, CA, USA
J Thorac Cardiovasc Surg 145:489-495.e1. 2013..The cardiac workload associated with various types of aortic obstruction was determined using computational fluid dynamic simulations...
- Noninvasive assessment of pulmonary arterial capacitance by echocardiographyMark K Friedberg
Division of Pediatric Cardiology, Stanford University, Stanford, California, USA
J Am Soc Echocardiogr 20:186-90. 2007..We investigated whether PAC can be estimated noninvasively by echocardiography...
- Morphometry-based impedance boundary conditions for patient-specific modeling of blood flow in pulmonary arteriesRyan L Spilker
Department of Mechanical Engineering, Stanford University, Clark Center E350B, 318 Campus Drive, Stanford, CA 94305 5431, USA
Ann Biomed Eng 35:546-59. 2007..This method of coupling image-based and morphometry-based models could enable increased fidelity in pulmonary hemodynamic simulation...
- New insights into pacemaker lead-induced venous occlusion: simulation-based investigation of alterations in venous biomechanicsAnna Lonyai
School of Medicine, Stanford University, Palo Alto, CA, USA
Cardiovasc Eng 10:84-90. 2010..This methodology may add to our understanding of the development of lead-induced thrombosis and occlusion in the clinical arena, and enable the development of new strategies to avoid such complications...
- Hemodynamic Effects of Phenylephrine, Vasopressin, and Epinephrine in Children With Pulmonary Hypertension: A Pilot StudyStephanie L Siehr
1Division of Pediatric Cardiology, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA 2Department of Bioengineering, Stanford University School of Medicine, Palo Alto, CA 3Division of Pediatric Anesthesiology, Department of Anesthesiology, Stanford University School of Medicine, Palo Alto, CA
Pediatr Crit Care Med 17:428-37. 2016..Currently, there are no therapeutic guidelines for managing an acute crisis. This pilot study examined the hemodynamic effects of phenylephrine, arginine vasopressin, and epinephrine in pediatric patients with pulmonary hypertension...
- Electrical and mechanical dyssynchrony in pediatric pulmonary hypertensionAllison C Hill
Department of Pediatrics, Division of Cardiology, Stanford University Medical School, Palo Alto, CA, USA
J Heart Lung Transplant 31:825-30. 2012..We examined the prevalence of electrical and mechanical dyssynchrony in pediatric PH patients...
- Food and Drug Administration (FDA) postmarket reported side effects and adverse events associated with pulmonary hypertension therapy in pediatric patientsDawn M Maxey
Department of Pediatrics Cardiology, Stanford University Medical Center Lucile Packard Children s Hospital, 750 Welch Road, Suite 305, Palo Alto, CA, 94304, USA
Pediatr Cardiol 34:1628-36. 2013..The discovery of AEs not previously reported will better inform those caring for these complex and critically ill children, and the large number of deaths suggest they may be underreported in current literature...
- Children with pulmonary arterial hypertension and prostanoid therapy: long-term hemodynamicsStephanie L Siehr
Division of Pediatric Cardiology, Department of Pediatrics, Stanford University, Palo Alto, California 94304, USA
J Heart Lung Transplant 32:546-52. 2013..Little is known about longitudinal hemodynamics and outcomes of epoprostenol, treprostinil, and transitions from epoprostenol to treprostinil...
- A method for quantitative characterization of growth in the 3-D structure of rat pulmonary arteriesHedi Razavi
Department of Bioengineering, Stanford University, Stanford, CA 94305, USA
Microvasc Res 83:146-53. 2012..With this new technique, the pulmonary vasculature can now be studied in a whole lung animal model to better understand the global effects of disease on vascular structure...
- Identifying cardiac transplant rejection in children: diagnostic utility of echocardiography, right heart catheterization and endomyocardial biopsy dataDavid N Rosenthal
Department of Pediatrics, Stanford University, Stanford, California, USA
J Heart Lung Transplant 23:323-9. 2004..The purpose of this study is to evaluate the role of echocardiography and hemodynamic catheterization data compared with endomyocardial biopsy results, in rejection surveillance for the pediatric heart transplant recipient...
- Quantitative characterization of postnatal growth trends in proximal pulmonary arteries in rats by phase-contrast magnetic resonance imagingHedi Razavi
Dept of Bioengineering, Clark Center Rm S165, 318 Campus Dr, Stanford, CA 94305 5444, USA
Am J Physiol Lung Cell Mol Physiol 301:L368-79. 2011..This study is the first to quantitatively describe changes in RPA and LPA flows and sizes with development and to apply phase-contrast MRI techniques to pulmonary arteries in rats...
- Ketamine does not increase pulmonary vascular resistance in children with pulmonary hypertension undergoing sevoflurane anesthesia and spontaneous ventilationGlyn D Williams
Department of Anesthesia, Stanford University School of Medicine, Stanford, California 94305 5640, USA
Anesth Analg 105:1578-84, table of contents. 2007..In this prospective, open label study, we evaluated the hemodynamic responses to ketamine in children with pulmonary hypertension (mean pulmonary artery pressure >25 mm Hg)...
- Percutaneous pulmonary valve placement in a 10-month-old patient using a hand crafted stent-mounted porcine valveJeffrey A Feinstein
Department of Pediatrics, Stanford University, California, USA
Catheter Cardiovasc Interv 67:644-9. 2006..At 10 months of age, this case represents the youngest patient to undergo percutaneous valve placement and documents the technical feasibility of the procedure...
- Temporary IVC filtration before patent foramen ovale closure in a patient with paradoxic embolismMary Beth Lewis-Carey
Department of Vascular and Interventional Radiology, Stanford University Medical Center, Room H3648, 300 Pasteur Drive, Stanford, California 94305 5642, USA
J Vasc Interv Radiol 13:1275-8. 2002..Systemic and catheter-directed thrombolysis, IVC filtration, and percutaneous closure of a PFO were performed in an effort to return the patient to the level of competitiveness she desired...
- Flow simulations and validation for the first cohort of patients undergoing the Y-graft Fontan procedureWeiguang Yang
Department of Pediatrics Cardiology, Stanford University, Palo Alto, Calif Electronic address
J Thorac Cardiovasc Surg 149:247-55. 2015....
- Validation of the Innocor device for noninvasive measurement of oxygen consumption in children and adultsShreya S Sheth
Department of Pediatrics Cardiology, Stanford University School of Medicine, Stanford, CA, USA
Pediatr Cardiol 34:847-52. 2013..This trend was not seen in adults. The Innocor system has excellent correlation with the Douglas bag and shows promise for noninvasive measurement of VO2 and CO in the school-age pediatric population...
- Angiojet catheter-based thrombectomy in a neonate with postoperative pulmonary embolismJeremy P Feldman
Department of Medicine, Stanford University, Stanford, California, USA
Catheter Cardiovasc Interv 66:442-5. 2005..The patient had immediate improvement in gas exchange and was able to be weaned from the ventilator shortly thereafter. This represents the first published use of mechanical thrombectomy in a postoperative neonate...
- Relative lung perfusion distribution in normal lung scans: observations and clinical implicationsChristopher P Cheng
Department of Mechanical Engineering, Stanford University, Stanford, CA, USA
Congenit Heart Dis 1:210-6. 2006..These values of normal relative perfusion will be useful for establishing what is abnormal and for clinical decisions related to various pulmonary vascular diseases...
- A novel echocardiographic Doppler method for estimation of pulmonary arterial pressuresMark K Friedberg
Division of Pediatric Cardiology, The Lucile Packard Children s Hospital, Stanford University, Stanford, California, USA
J Am Soc Echocardiogr 19:559-62. 2006..We hypothesized that systolic PAp correlates with diastolic and mean PAp, and that this correlation can be used to estimate diastolic and mean PAp from Doppler flow data...
- Experience of percutaneous coronary intervention in the management of pediatric cardiac allograft vasculopathyEdythe B C Tham
Division of Pediatric Cardiology at Lucile Packard Children s Hospital, Stanford University, Stanford, California, USA
J Heart Lung Transplant 24:769-73. 2005....
- Adaptive outflow boundary conditions improve post-operative predictions after repair of peripheral pulmonary artery stenosisWeiguang Yang
Department of Pediatrics, School of Medicine, Stanford University, Stanford, CA, USA
Biomech Model Mechanobiol 15:1345-53. 2016..This suggests adaptive outflow boundary conditions should be incorporated into post-operative modeling in patients with complex PPS. ..
- Short- and long-term outcomes of necrotizing enterocolitis in infants with congenital heart diseaseSarah S Pickard
Divisions of Pediatric Surgery, Lucile Packard Children s Hospital and Stanford School of Medicine, Stanford University, Stanford, California 94304, USA
Pediatrics 123:e901-6. 2009..We compared the short- and long-term necrotizing enterocolitis-specific outcomes of infants with congenital heart disease with those of neonates without congenital heart disease...
- Blood flow conditions in the proximal pulmonary arteries and vena cavae: healthy children during upright cycling exerciseChristopher P Cheng
Department of Mechanical Engineering, Stanford University, Stanford, CA 94305 4038, USA
Am J Physiol Heart Circ Physiol 287:H921-6. 2004..During seated rest, the SVC-to-IVC venous return ratio is 50/50%. With light/moderate cycling exercise, IVC flow increases by threefold, whereas SVC remains essentially constant...
- Electrical resynchronization: a novel therapy for the failing right ventricleAnne M Dubin
Department of Pediatrics, Stanford University, 750 Welch Rd, Suite 305, Stanford, Calif 94304, USA
Circulation 107:2287-9. 2003..RV problems may include right bundle-branch block (RBBB), volume loading, and chamber enlargement. Because the failing RV may have regional dyskinesis, we hypothesized that resynchronization therapy might augment its performance...
- Majewski osteodysplastic primordial dwarfism type II (MOPD II): expanding the vascular phenotypeMichael B Bober
Division of Genetics, Department of Pediatrics, AI duPont Hospital for Children, Wilmington, Delaware 19803, USA
Am J Med Genet A 152:960-5. 2010..Emergent evaluation is also needed when other neurologic or cardiac symptoms are present...
- CT-defined phenotype of pulmonary artery stenoses in Alagille syndromeRenee M Rodriguez
Department of Pediatrics Cardiology, Packard Children s Hospital, Stanford University Medical Center, 750 Welch Road, Suite 305, Palo Alto, CA, 94304, USA
Pediatr Radiol 46:1120-7. 2016..Alagille syndrome is a rare disorder commonly associated with pulmonary artery stenosis. Studies exist discussing the cardiovascular sequela but no consistent phenotype, or pattern of pulmonary artery stenosis, has been described...
- Accuracy of Pulse Oximeters Intended for Hypoxemic Pediatric PatientsBronwyn U Harris
1Department of Pediatrics Cardiology, Stanford University School of Medicine, Palo Alto, CA 2Department of Anesthesiology and Critical Care Pediatric Anesthesiology, Stanford University School of Medicine, Palo Alto, CA 3Department of Epidemiology and Biostatistics, University of California, San Francisco, CA
Pediatr Crit Care Med 17:315-20. 2016..This study's purpose was to evaluate two sensors with claims of improved accuracy in children with saturations less than 85%...
- Computational modeling and engineering in pediatric and congenital heart diseaseAlison L Marsden
aDepartments of Pediatrics and Bioengineering, Institute for Computational and Mathematical Engineering bDepartments of Pediatrics and Bioengineering, Stanford University, Stanford, California, USA
Curr Opin Pediatr 27:587-96. 2015..We review recent developments in the use of computational simulations in pediatric and congenital heart disease, describe the clinical impact in modeling in single-ventricle patients, and provide an overview of emerging areas...
- Congenital extrahepatic portosystemic shunt associated with heterotaxy and polyspleniaBeverley Newman
Department of Radiology, Stanford University School of Medicine, Lucile Packard Children s Hospital, 725 Welch Road, Stanford, CA 94305, USA
Pediatr Radiol 40:1222-30. 2010..Heterotaxy with polysplenia is associated with many cardiovascular anomalies including the occasional occurrence of congenital extrahepatic portosystemic shunts (CEPS). Missing this anomaly can lead to inappropriate and ineffective therapy...
- Regression of severe pulmonary arteriovenous malformations after Fontan revision and "hepatic factor" reroutingNancy A Pike
Division of Cardiothoracic Surgery, David Geffen School of Medicine at University of California Los Angeles, UCLA Box 951741, Los Angeles, CA 90095 1741, USA
Ann Thorac Surg 78:697-9. 2004..We present a case in which successful H-type Fontan revision with rerouting of hepatic venous flow through a hemiazygous vein successfully reversed the progression of severe left pulmonary arteriovenous malformations...
- Extension of Doppler-derived echocardiographic measures of pulmonary vascular resistance to patients with moderate or severe pulmonary vascular diseaseAntonios P Vlahos
Child Health Department, Pediatric Cardiology Division, University of Ioannina, Ioannina, Greece
J Am Soc Echocardiogr 21:711-4. 2008..Pulmonary vascular resistance (PVR) is a critical parameter in the assessment and treatment of patients with pulmonary hypertension, regardless of origin. Noninvasive estimation of PVR could be helpful...
- Noninherited risk factors and congenital cardiovascular defects: current knowledge: a scientific statement from the American Heart Association Council on Cardiovascular Disease in the Young: endorsed by the American Academy of PediatricsKathy J Jenkins
Boston Children s Hospital, USA
Circulation 115:2995-3014. 2007..Issues related to pregnancy monitoring are discussed. Knowledge gaps and future sources of new information on risk factors are described...
- Surgical and interventional therapies for pulmonary arterial hypertensionJulie K Olsson
Division of Pulmonary and Critical Care Medicine, Stanford University School of Medicine, CA 94305, USA
Semin Respir Crit Care Med 26:417-28. 2005..Lung transplantation should be considered for patients with all forms of PAH who demonstrate advanced or progressive disease...
- Usefulness of epoprostenol therapy in the severely ill adolescent/adult with Eisenmenger physiologySusan M Fernandes
Boston Adult Congenital Heart Service, Children s Hospital and Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Am J Cardiol 91:632-5. 2003