Frederick E Dewey
Affiliation: Stanford University
- Ventricular arrhythmias during clinical treadmill testing and prognosisFrederick E Dewey
Stanford University Medical School, Palo Alto, California, USA
Arch Intern Med 168:225-34. 2008..Therefore, we aimed to evaluate the clinical correlates and prognostic significance of exercise-associated premature ventricular complexes (PVCs) during and after exercise testing...
- Statin use and ventricular arrhythmias during clinical treadmill testingFrederick E Dewey
Department of Internal Medicine, Stanford University, Palo Alto, California, USA
J Cardiovasc Electrophysiol 20:193-9. 2009..Statin use reduces the incidence of resting ventricular arrhythmias in patients with coronary artery disease; however, the relationship between statin use and exercise-induced ventricular arrhythmias has not been investigated...
- Hemoglobin levels predict exercise performance, ST-segment depression, and outcome in patients referred for routine exercise treadmill testingMichael J Lipinski
Veterans Affairs Palo Alto Health Care System, Stanford University Administration Health Care System, Palo Alto, California, USA
Clin Cardiol 32:E22-31. 2009..While the role of hemoglobin in heart failure and renal disease has been investigated, little is known about its effect on clinical exercise test performance and mortality in patients referred for routine exercise treadmill testing (ETT)...
- Prognostic value of heart rate increase at onset of exercise testingNicholas J Leeper
Stanford University Medical Center, Stanford University Medical School, Calif, USA
Circulation 115:468-74. 2007..Our aim was to evaluate the prognostic value of early heart rate parameters in patients referred for routine clinical treadmill testing...
- Personal omics profiling reveals dynamic molecular and medical phenotypesRui Chen
Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA
Cell 148:1293-307. 2012..This study demonstrates that longitudinal iPOP can be used to interpret healthy and diseased states by connecting genomic information with additional dynamic omics activity...
- Added value of a resting ECG neural network that predicts cardiovascular mortalityMARCO V PEREZ
Stanford University School of Medicine, Cardiovascular Medicine, Stanford, CA, USA
Ann Noninvasive Electrocardiol 14:26-34. 2009..The resting 12-lead electrocardiogram (ECG) remains the most commonly used test in evaluating patients with suspected cardiovascular disease. Prognostic values of individual findings on the ECG have been reported but may be of limited use...
- Prognostic value of double product reserveAmir H Sadrzadeh Rafie
Stanford University Medical Center, Division of Cardiovascular Medicine, 300 Pasteur Dr Falk CVRC, Stanford, CA 94305 5406, USA
Eur J Cardiovasc Prev Rehabil 15:541-7. 2008..We aimed to assess the prognostic power of double product (DP) parameters in patients referred for standard exercise testing...
- Age-adjusted modification of the Duke Treadmill Score nomogramAmir H Sadrzadeh Rafie
Division of Cardiovascular Medicine, Stanford University Medical Center, Stanford, CA 94305 5406, USA
Am Heart J 155:1033-8. 2008..We aimed to determine if age could improve the prognostic power of the DTS and if so, to modify the DTS nomogram to include age...
- Clinical assessment incorporating a personal genomeEuan A Ashley
Center for Inherited Cardiovascular Disease, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA
Lancet 375:1525-35. 2010..The cost of genomic information has fallen steeply, but the clinical translation of genetic risk estimates remains unclear. We aimed to undertake an integrated analysis of a complete human genome in a clinical context...
- Electrocardiographic predictors of atrial fibrillationMARCO V PEREZ
Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA
Am Heart J 158:622-8. 2009..Noninvasive predictors of AF may help identify patients at risk of developing AF. Our objective was to identify the electrocardiographic characteristics associated with onset of AF...
- Systems Genomics Identifies a Key Role for Hypocretin/Orexin Receptor-2 in Human Heart FailureMARCO V PEREZ
Center for Inherited Cardiovascular Disease, Division of Cardiovascular Medicine, Stanford University, Stanford, California
J Am Coll Cardiol 66:2522-33. 2015..We hypothesized that identifying genetic variants of HF that associate with response to medical therapy would elucidate the genetic basis of cardiac function...
- Performance comparison of whole-genome sequencing platformsHugo Y K Lam
Department of Genetics, Stanford University, Stanford, California, USA
Nat Biotechnol 30:78-82. 2012..Our results have important implications for understanding the accuracy and completeness of the genome sequencing platforms...
- Autonomic nervous system interaction with the cardiovascular system during exerciseJames V Freeman
Division of Cardiovascular Medicine, Stanford University Medical Center and Veterans Affairs Health Care System, Palo Alto, CA 94304, USA
Prog Cardiovasc Dis 48:342-62. 2006..Research continues seeking to refine these exercise measurements and further define their prognostic value. Future findings should augment the power of the exercise test in risk-stratifying cardiovascular patients...
- Sequence to Medical Phenotypes: A Framework for Interpretation of Human Whole Genome DNA Sequence DataFrederick E Dewey
Stanford Center for Inherited Cardiovascular Disease, Stanford University, Stanford, California, United States of America Stanford Cardiovascular Institute, Stanford University, Stanford, California, United States of America Division of Cardiovascular Medicine, Stanford University, Stanford, California, United States of America
PLoS Genet 11:e1005496. 2015..We also nominate a new candidate gene in congenital arrhythmia, ATP2B4, and provide experimental evidence of a regulatory role for variants discovered using this framework. ..
- Molecular diagnosis of long QT syndrome at 10 days of life by rapid whole genome sequencingJames R Priest
Division of Pediatric Cardiology, Stanford University School of Medicine, Stanford University, Stanford, California Child Health Research Institute Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, California
Heart Rhythm 11:1707-13. 2014....
- Systems biology of heart failure, challenges and hopesFrederick E Dewey
Division of Cardiovascular Medicine, Stanford Hospital and Clinics, Stanford, California, USA
Curr Opin Cardiol 26:314-21. 2011..Here we consider recent advances in understanding the integrative multiscale biology, or systems biology, of heart failure and present a framework for future work in the area...
- Phased whole-genome genetic risk in a family quartet using a major allele reference sequenceFrederick E Dewey
Center for Inherited Cardiovascular Disease, Division of Cardiovascular Medicine, Stanford University, Stanford, California, USA
PLoS Genet 7:e1002280. 2011..These ethnicity-specific, family-based approaches to interpretation of genetic variation are emblematic of the next generation of genetic risk assessment using whole-genome sequencing...
- Prediction of cardiovascular death using a novel heart rate recovery parameterDavid M Hadley
Cardiac Science, Bothell, WA, USA
Med Sci Sports Exerc 40:1072-9. 2008..We hypothesized that a score normalized for HR increase would better isolate the vagal influences in recovery from the sympathetic influences supporting maximal exercise...
- Novel predictor of prognosis from exercise stress testing: heart rate variability response to the exercise treadmill testFrederick E Dewey
Stanford University School of Medicine, Stanford, CA, USA
Am Heart J 153:281-8. 2007..We aimed to evaluate the prognostic power of exercise-induced HRV during and after standard exercise testing...