J Wesson Ashford
Affiliation: Stanford University
- Designing a Brief Alzheimer Screen (BAS)Marta S Mendiondo
School of Public Health, Sanders Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA
J Alzheimers Dis 5:391-8. 2003..With advances in the treatment of Alzheimer's disease (AD), clinical focus has shifted to early patient identification. Memory recall tests and category fluency distinguish normal individuals from early AD patients...
- MR spectroscopy for assessment of memantine treatment in mild to moderate Alzheimer dementiaJ W Ashford
War Related Illness and Injury Study Center, VA Palo Alto Health Care System, Palo Alto, CA, USA
J Alzheimers Dis 26:331-6. 2011..The objective of this study was to test whether memantine would slow or prevent the loss of neurons in mild to moderate AD patients...
- P300 energy loss in aging and Alzheimer's diseaseJ Wesson Ashford
War Related Illness and Injury Study Center, VA Palo Alto Health Care System, Palo Alto, CA 94304 1290, USA
J Alzheimers Dis 26:229-38. 2011..The approaches to calculating the P300 described here are potentially useful for measuring specific neural systems affected by aging and AD...
- APOE genotype effects on Alzheimer's disease onset and epidemiologyJ Wesson Ashford
Stanford VA Alzheimer Center, Palo Alto, CA 94304 1207, USA
J Mol Neurosci 23:157-65. 2004..This paper reviews the onset, diagnosis, and epidemiology of AD, specifically with regard to the APOE genotype and the interaction of the genotype with age...
- What is aging? What is its role in Alzheimer's disease? What can we do about it?J Wesson Ashford
Stanford VA Alzheimer Center, Palo Alto, CA 94304 1207, USA
J Alzheimers Dis 7:247-53; discussion 255-62. 2005
- Measuring memory in large group settings using a continuous recognition testJ Wesson Ashford
Stanford VA Aging Clinical Research Center, VA Palo Alto Health Care System, Palo Alto, CA 94304 1290, USA
J Alzheimers Dis 27:885-95. 2011..There were no significant effects of gender on test performance. Such memory tests represent a practical and novel approach to screen for the signs of early dementia...
- Apolipoprotein E epsilon4 influences on episodic recall and brain structures in aging pilotsMaheen M Adamson
Department of Veterans Affairs, Palo Alto, CA 94304, USA
Neurobiol Aging 31:1059-63. 2010..These findings point to basic memory testing as a sensitive tool for detecting APOE epsilon4-related influences on memory in aging workers...
- Acetylcholinesterase inhibitor in combination with cognitive training in older adultsJerome A Yesavage
Palo Alto Veterans Affairs Health Care System, Palo Alto, CA, USA
J Gerontol B Psychol Sci Soc Sci 63:P288-94. 2008....
- Strategies to reduce site differences in multisite studies: a case study of Alzheimer disease progressionArt Noda
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford University, Stanford, CA 94305, USA
Am J Geriatr Psychiatry 14:931-8. 2006....
- Memantine is associated with longer survival than donepezil in a Veterans Affairs prescription database, 1997 to 2008Laura C Lazzeroni
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA
J Alzheimers Dis 36:791-8. 2013....
- The impact of depression on Veterans with PTSD and traumatic brain injury: a diffusion tensor imaging studyLinda Isaac
War Related Illness and Injury Study Center, The Veterans Affairs Palo Alto Healthcare System, Palo Alto, USA Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA Electronic address
Biol Psychol 105:20-8. 2015..Microstructural changes of white matter were found in the cingulum and UF. Fractional anisotropy (FA) was lower in Veterans with DEP compared to those without DEP. ..
- Neuropsychiatric diagnosis and management of chronic sequelae of war-related mild to moderate traumatic brain injuryJoshua D Halbauer
Department of Veterans Affairs VA Palo Alto Health Care System, Palo Alto, CA 94304, USA
J Rehabil Res Dev 46:757-96. 2009..With a multidimensional approach (such as the biopsychosocial model) applied to each symptom cluster, psychological, occupational, and social dysfunction can be delineated and managed...
- ApoE genotype accounts for the vast majority of AD risk and AD pathologyJacob Raber
Departments of Behavioral Neuroscience and Neurology, L470, ONPRC, Oregon Health and Science University, 3181 S W Sam Jackson Park Road, Portland, OR 97201, USA
Neurobiol Aging 25:641-50. 2004..Thus, the epidemiologic and basic science evidence suggest that apoE genotype accounts for the vast majority of AD risk and pathology...
- Non-familial Alzheimer's disease is mainly due to genetic factorsJ Wesson Ashford
Department of Psychiatry, Sanders Brown Center on Aging, University of Kentucky, Veterans Affairs Medical Center, Lexington, KY 40536 0230, USA
J Alzheimers Dis 4:169-77. 2002..This paper further reviews the mechanisms associated with AD causation for APOE and other candidate genes and implications for the development of prevention strategies...
- Leptin reduces Alzheimer's disease-related tau phosphorylation in neuronal cellsSteven J Greco
Neurotez Inc, Bridgewater, NJ, USA
Biochem Biophys Res Commun 376:536-41. 2008..Thus, leptin, which ameliorates both amyloid beta and tau-related pathological pathways, holds promise as a novel therapeutic for Alzheimer's disease...
- Live discussion. From here to there: AbetaPP as an axonal transport receptor--how could this explain neurodegeneration in AD. 15 July 2002Larry Goldstein
University of California, San Diego, USA
J Alzheimers Dis 5:483-9. 2003
- Neuroplasticity in Alzheimer's diseaseBruce Teter
Department of Medicine, University of California Los Angeles, California and Veteran s Affairs Greater Los Angeles Healthcare System, Sepulveda, California 91343, USA
J Neurosci Res 70:402-37. 2002..These mechanisms, however, may contribute to the vulnerability to neurodegenerative disease. They may also be exploited therapeutically to help alleviate the suffering from neurodegenerative conditions...
- ApoE4: is it the absence of good or the presence of bad?J Wesson Ashford
101 Sanders Brown Building, University of Kentucky, College of Medicine, University of Kentucky, Lexington, KY 40536 0230, USA
J Alzheimers Dis 4:141-3. 2002