Andre Altmann

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. doi request reprint Detecting rare variants for psychiatric disorders using next generation sequencing: a methods primer
    Andre Altmann
    Department of Neurology and Neurological Sciences, Functional Imaging in Neurodegenerative Disorders Laboratory, Stanford University, Stanford, CA, USA
    Curr Psychiatry Rep 15:333. 2013
  2. doi request reprint A beginners guide to SNP calling from high-throughput DNA-sequencing data
    Andre Altmann
    Statistical Genetics, Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Hum Genet 131:1541-54. 2012
  3. pmc Functional coding variants in SLC6A15, a possible risk gene for major depression
    Carina Quast
    Max Planck Institute of Psychiatry, Munich, Germany
    PLoS ONE 8:e68645. 2013
  4. doi request reprint Rare variants in TMEM132D in a case-control sample for panic disorder
    Carina Quast
    Max Planck Institute of Psychiatry, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 159:896-907. 2012
  5. pmc vipR: variant identification in pooled DNA using R
    Andre Altmann
    Department of Statistical Genetics, Max Planck Institute of Psychiatry, Munich, Germany
    Bioinformatics 27:i77-84. 2011
  6. pmc Connecting Anxiety and Genomic Copy Number Variation: A Genome-Wide Analysis in CD-1 Mice
    Julia Brenndörfer
    Department of Behavioral Neuroendocrinology, Max Planck Institute of Psychiatry, Munich, Germany
    PLoS ONE 10:e0128465. 2015
  7. doi request reprint A polymorphism in the Crhr1 gene determines stress vulnerability in male mice
    Christiana Labermaier
    Max Planck Institute of Psychiatry C L, C K, J H, C D, A A, P W, J A, C Q, K V W, S H S, L C, R W A, J B, R L, F H, M U, F H, E B B, M V S, 80804 Munich, Germany Lundbeck Research USA K A J, Paramus, New Jersey 07652 and Johannes Gutenberg University Medical Center M B M, 55131 Mainz, Germany
    Endocrinology 155:2500-10. 2014
  8. pmc Re-Annotator: Annotation Pipeline for Microarray Probe Sequences
    Janine Arloth
    Translational Research Department, Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804, Munich, Germany
    PLoS ONE 10:e0139516. 2015
  9. pmc Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders
    Janine Arloth
    Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich 80804, Germany
    Neuron 86:1189-202. 2015
  10. pmc Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder
    Divya Mehta
    Max Planck Institute of Psychiatry, 80804 Munich, Germany
    Proc Natl Acad Sci U S A 110:8302-7. 2013

Collaborators

Detail Information

Publications12

  1. doi request reprint Detecting rare variants for psychiatric disorders using next generation sequencing: a methods primer
    Andre Altmann
    Department of Neurology and Neurological Sciences, Functional Imaging in Neurodegenerative Disorders Laboratory, Stanford University, Stanford, CA, USA
    Curr Psychiatry Rep 15:333. 2013
    ..Thereby, it aims to introduce the emerging field of MPS into neuropsychiatric research and might serve as a guide for further studies...
  2. doi request reprint A beginners guide to SNP calling from high-throughput DNA-sequencing data
    Andre Altmann
    Statistical Genetics, Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Hum Genet 131:1541-54. 2012
    ..To this end, we employ several alignment programs and SNP calling routines for highlighting the fact that the choice of the tools significantly affects the final results...
  3. pmc Functional coding variants in SLC6A15, a possible risk gene for major depression
    Carina Quast
    Max Planck Institute of Psychiatry, Munich, Germany
    PLoS ONE 8:e68645. 2013
    ..As statistically significant association for rare variants might only be achieved in extremely large samples (N >70,000) functional exploration may shed light on putatively disease-relevant variants...
  4. doi request reprint Rare variants in TMEM132D in a case-control sample for panic disorder
    Carina Quast
    Max Planck Institute of Psychiatry, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 159:896-907. 2012
    ..Our data suggest that not only common but also putatively functional and/or rare variants within TMEM132D might contribute to the risk to develop anxiety disorders...
  5. pmc vipR: variant identification in pooled DNA using R
    Andre Altmann
    Department of Statistical Genetics, Max Planck Institute of Psychiatry, Munich, Germany
    Bioinformatics 27:i77-84. 2011
    ..The resulting sequence data, however, poses a bioinformatics challenge: the discrimination of sequencing errors from real sequence variants present at a low frequency in the DNA pool...
  6. pmc Connecting Anxiety and Genomic Copy Number Variation: A Genome-Wide Analysis in CD-1 Mice
    Julia Brenndörfer
    Department of Behavioral Neuroendocrinology, Max Planck Institute of Psychiatry, Munich, Germany
    PLoS ONE 10:e0128465. 2015
    ..0051) with genes within HAB/LAB CNVs. Thus, here we provide what is to our knowledge the first extensive catalogue of CNVs in CD-1 mice and potential corresponding candidate genes linked to anxiety-related behavior in mice. ..
  7. doi request reprint A polymorphism in the Crhr1 gene determines stress vulnerability in male mice
    Christiana Labermaier
    Max Planck Institute of Psychiatry C L, C K, J H, C D, A A, P W, J A, C Q, K V W, S H S, L C, R W A, J B, R L, F H, M U, F H, E B B, M V S, 80804 Munich, Germany Lundbeck Research USA K A J, Paramus, New Jersey 07652 and Johannes Gutenberg University Medical Center M B M, 55131 Mainz, Germany
    Endocrinology 155:2500-10. 2014
    ..Our results suggest that patients with a specific genetic predisposition in the CRHR1 gene together with an exposure to chronic stress may benefit from a treatment selectively antagonizing CRHR1 hyperactivity. ..
  8. pmc Re-Annotator: Annotation Pipeline for Microarray Probe Sequences
    Janine Arloth
    Translational Research Department, Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804, Munich, Germany
    PLoS ONE 10:e0139516. 2015
    ..The Re-Annotator pipeline is freely available at http://sourceforge.net/projects/reannotator along with re-annotated files for Illumina microarrays HumanHT-12 v3/v4 and MouseRef-8 v2. ..
  9. pmc Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders
    Janine Arloth
    Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich 80804, Germany
    Neuron 86:1189-202. 2015
    ....
  10. pmc Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder
    Divya Mehta
    Max Planck Institute of Psychiatry, 80804 Munich, Germany
    Proc Natl Acad Sci U S A 110:8302-7. 2013
    ..These results contribute to a better understanding of the extent of influence of differences in trauma exposure on pathophysiological processes in stress-related psychiatric disorders and may have implications for personalized medicine...
  11. pmc Regional brain hypometabolism is unrelated to regional amyloid plaque burden
    Andre Altmann
    1 FIND Lab, Department of Neurology and Neurological Sciences, Stanford University, Stanford California, USA
    Brain 138:3734-46. 2015
    ..Instead, cortical hypometabolism appears to be linked to global amyloid burden. Thus we conclude that regional fibrillar amyloid deposition has little to no association with regional hypometabolism...
  12. pmc Sex modifies the APOE-related risk of developing Alzheimer disease
    Andre Altmann
    Stanford Center for Memory Disorders, Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA
    Ann Neurol 75:563-73. 2014
    ..We examined the APOE4-by-sex interaction in conversion risk (from healthy aging to mild cognitive impairment (MCI)/AD or from MCI to AD) and cerebrospinal fluid (CSF) biomarker levels...