Genomes and Genes
Affiliation: St. Jude Children's Research Hospital
- CIPP, a novel multivalent PDZ domain protein, selectively interacts with Kir4.0 family members, NMDA receptor subunits, neurexins, and neuroliginsC Kurschner
Department of Developmental Neurobiology, Saint Jude Children s Research Hospital, Memphis, Tennessee, 38105, USA
Mol Cell Neurosci 11:161-72. 1998..The functional consequences of CIPP expression on Kir4.1 channels were studied using whole-cell voltage clamp techniques in Kir4.1 transfected COS-7 cells. On average, Kir4.1 current densities were doubled by cotransfection with CIPP...
- c-Maf interacts with c-Myb to regulate transcription of an early myeloid gene during differentiationS P Hedge
Department of Experimental Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
Mol Cell Biol 18:2729-37. 1998..This pattern matched that of CD13/APN reporter gene expression, indicating that Maf modulation of c-Myb activity may be an important mechanism for the control of gene transcription during hematopoietic cell development...
- The Lnx family proteins function as molecular scaffolds for Numb family proteinsD S Rice
Department of Developmental Neurobiology, Saint Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
Mol Cell Neurosci 18:525-40. 2001..Therefore, our findings suggest that Lnx proteins may serve as molecular scaffolds that localize unrelated, interacting proteins, such as Numb, to specific subcellular sites...
- USF2/FIP associates with the b-Zip transcription factor, c-Maf, via its bHLH domain and inhibits c-Maf DNA binding activityC Kurschner
Department of Developmental Neurobiology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
Biochem Biophys Res Commun 231:333-9. 1997..These data suggest a tetrameric configuration for Maf-USF2 complexes. In the presence of USF2, the DNA binding activity of c-Maf was markedly reduced. Therefore, USF2 and c-Maf may interact to regulate gene expression...