R Rico-Hesse

Summary

Affiliation: Southwest Foundation for Biomedical Research
Country: USA

Publications

  1. pmc Microevolution and virulence of dengue viruses
    Rebeca Rico-Hesse
    Southwest Foundation for Biomedical Research, San Antonio, Texas 78227, USA
    Adv Virus Res 59:315-41. 2003
  2. pmc Dengue virus tropism in humanized mice recapitulates human dengue fever
    Javier Mota
    Department of Virology and Immunology, Southwest Foundation for Biomedical Research, San Antonio, Texas, United States of America
    PLoS ONE 6:e20762. 2011
  3. pmc Variation in vector competence for dengue viruses does not depend on mosquito midgut binding affinity
    Jonathan Cox
    Virology and Immunology, Southwest Foundation for Biomedical Research, San Antonio, Texas, United States of America
    PLoS Negl Trop Dis 5:e1172. 2011
  4. pmc Dengue virus virulence and transmission determinants
    R Rico-Hesse
    Southwest Foundation for Biomedical Research, San Antonio, TX 78227, USA
    Curr Top Microbiol Immunol 338:45-55. 2010
  5. pmc Dengue virus evolution and virulence models
    Rebeca Rico-Hesse
    Department of Virology and Immunology, Southwest Foundation for Biomedical Research, San Antonio, TX 78245 0549, USA
    Clin Infect Dis 44:1462-6. 2007
  6. pmc Isolation of a hepadnavirus from the woolly monkey, a New World primate
    R E Lanford
    Departments of Virology and Immunology, Southwest Foundation for Biomedical Research, 7620 Northwest Loop 410, San Antonio, TX 78227, USA
    Proc Natl Acad Sci U S A 95:5757-61. 1998
  7. pmc Efficiency of dengue serotype 2 virus strains to infect and disseminate in Aedes aegypti
    Philip M Armstrong
    Department of Virology and Immunology, Southwest Foundation for Biomedical Research, San Antonio, Texas 78245 0549, USA
    Am J Trop Med Hyg 68:539-44. 2003
  8. pmc Humanized mice show clinical signs of dengue fever according to infecting virus genotype
    Javier Mota
    Department of Virology and Immunology, Southwest Foundation for Biomedical Research, San Antonio, TX 78227, USA
    J Virol 83:8638-45. 2009
  9. pmc Differential susceptibility of Aedes aegypti to infection by the American and Southeast Asian genotypes of dengue type 2 virus
    P M Armstrong
    Department of Virology and Immunology, Southwest Foundation for Biomedical Research, San Antonio, TX 78245 0549, USA
    Vector Borne Zoonotic Dis 1:159-68. 2001
  10. pmc Dengue virus structural differences that correlate with pathogenesis
    K C Leitmeyer
    Department of Virology and Immunology, Southwest Foundation for Biomedical Research, San Antonio, Texas 78227 5301, USA
    J Virol 73:4738-47. 1999

Research Grants

Collaborators

Detail Information

Publications17

  1. pmc Microevolution and virulence of dengue viruses
    Rebeca Rico-Hesse
    Southwest Foundation for Biomedical Research, San Antonio, Texas 78227, USA
    Adv Virus Res 59:315-41. 2003
    ....
  2. pmc Dengue virus tropism in humanized mice recapitulates human dengue fever
    Javier Mota
    Department of Virology and Immunology, Southwest Foundation for Biomedical Research, San Antonio, Texas, United States of America
    PLoS ONE 6:e20762. 2011
    ..We demonstrated that the pathology of dengue virus infection in these mice follows that reported in human patients, making this the first valid and relevant model for studying dengue fever pathogenesis in humans...
  3. pmc Variation in vector competence for dengue viruses does not depend on mosquito midgut binding affinity
    Jonathan Cox
    Virology and Immunology, Southwest Foundation for Biomedical Research, San Antonio, Texas, United States of America
    PLoS Negl Trop Dis 5:e1172. 2011
    ..We tested the hypothesis that genetic differences in dengue viruses may result in differential binding to the midgut of the primary vector, Aedes aegypti, resulting in increased transmission or vectorial capacity...
  4. pmc Dengue virus virulence and transmission determinants
    R Rico-Hesse
    Southwest Foundation for Biomedical Research, San Antonio, TX 78227, USA
    Curr Top Microbiol Immunol 338:45-55. 2010
    ..Controversy regarding viral determinants of DENV pathogenesis and epidemiology will continue until virulence and transmissibility can be measured under various conditions...
  5. pmc Dengue virus evolution and virulence models
    Rebeca Rico-Hesse
    Department of Virology and Immunology, Southwest Foundation for Biomedical Research, San Antonio, TX 78245 0549, USA
    Clin Infect Dis 44:1462-6. 2007
    ..Therefore, new technologies are allowing us to better understand how specific virus variants cause more disease than others, and these virus variants should be targeted for detection, control, and treatment...
  6. pmc Isolation of a hepadnavirus from the woolly monkey, a New World primate
    R E Lanford
    Departments of Virology and Immunology, Southwest Foundation for Biomedical Research, 7620 Northwest Loop 410, San Antonio, TX 78227, USA
    Proc Natl Acad Sci U S A 95:5757-61. 1998
    ..Thus, we have isolated a hepadnavirus with a host intermediate between humans and rodents and establishes a new animal model for evaluation of antiviral therapies for treating HBV chronic infections...
  7. pmc Efficiency of dengue serotype 2 virus strains to infect and disseminate in Aedes aegypti
    Philip M Armstrong
    Department of Virology and Immunology, Southwest Foundation for Biomedical Research, San Antonio, Texas 78245 0549, USA
    Am J Trop Med Hyg 68:539-44. 2003
    ..Together, these findings suggest that Ae. aegypti tends to be more susceptible to infection by DEN-2 viruses of the SE Asian genotype than to those of the American genotype, and this may have epidemiologic implications...
  8. pmc Humanized mice show clinical signs of dengue fever according to infecting virus genotype
    Javier Mota
    Department of Virology and Immunology, Southwest Foundation for Biomedical Research, San Antonio, TX 78227, USA
    J Virol 83:8638-45. 2009
    ..These characteristics make this mouse model ideal for the study of dengue pathogenesis and the evaluation of vaccine attenuation and antivirals...
  9. pmc Differential susceptibility of Aedes aegypti to infection by the American and Southeast Asian genotypes of dengue type 2 virus
    P M Armstrong
    Department of Virology and Immunology, Southwest Foundation for Biomedical Research, San Antonio, TX 78245 0549, USA
    Vector Borne Zoonotic Dis 1:159-68. 2001
    ..Such an understanding of functional differences between viral strains and genotypes may ultimately improve surveillance and intervention strategies...
  10. pmc Dengue virus structural differences that correlate with pathogenesis
    K C Leitmeyer
    Department of Virology and Immunology, Southwest Foundation for Biomedical Research, San Antonio, Texas 78227 5301, USA
    J Virol 73:4738-47. 1999
    ..This new approach to the study of dengue virus genome differences should better reflect the true composition of viral RNA populations in the natural host and permit their association with pathogenesis...
  11. pmc Hepadnavirus infection in captive gibbons
    R E Lanford
    Department of Virology and Immunology, Southwest Regional Primate Research Center, Southwest Foundation for Biomedical Research, San Antonio, Texas 78227, USA
    J Virol 74:2955-9. 2000
    ..Phylogenetic analysis indicated that the gibbon isolates lie within the human HBV family, indicating that these HBV isolates most likely stem from infection of gibbons from a human source...
  12. pmc American genotype structures decrease dengue virus output from human monocytes and dendritic cells
    Raymond Cologna
    Department of Virology and Immunology, Southwest Foundation for Biomedical Research, San Antonio, Texas 78227, USA
    J Virol 77:3929-38. 2003
    ..The data suggest that these changes may be responsible for decreased dengue virus replication in human target cells and for virulence characteristics during infection...
  13. pmc Aedes aegypti vectorial capacity is determined by the infecting genotype of dengue virus
    Justin R Anderson
    Department of Virology and Immunology, Southwest Foundation for Biomedical Research, San Antonio, Texas 78245 0549, USA
    Am J Trop Med Hyg 75:886-92. 2006
    ..This may be one of the mechanisms through which more virulent flaviviruses spread and displace others globally...
  14. pmc Dengue fever in humanized NOD/SCID mice
    Dennis A Bente
    Department of Virology and Immunology, Southwest Foundation for Biomedical Research, 7620 NW Loop 410, San Antonio, TX 78227, USA
    J Virol 79:13797-9. 2005
    ..These results suggest this is a valuable model with which to study pathogenesis and test antidengue products...
  15. pmc Selection for virulent dengue viruses occurs in humans and mosquitoes
    Raymond Cologna
    Department of Virology and Immunology, Southwest Foundation for Biomedical Research, 7620 NW Loop 410, San Antonio, TX 78227, USA
    J Virol 79:853-9. 2005
    ..This fact implies that Southeast Asian genotype viruses will continue to displace other viruses, causing more hemorrhagic dengue epidemics...
  16. pmc Phylogenetic analysis of the envelope protein (domain III) of dengue 4 viruses
    Javier Mota
    Departamento de Arbovirus, Centro De Investigacion sobre Enfermedades Infecciosas, Instituto Nacional de Salud Publica, Cuernavaca, Morelos, Mexico
    Salud Publica Mex 44:228-36. 2002
    ..To evaluate the genetic variability of domain III of envelope (E) protein and to estimate phylogenetic relationships of dengue 4 (Den-4) viruses isolated in Mexico and from other endemic areas of the world...
  17. pmc High genetic divergence and recombination in Arenaviruses from the Americas
    Angela M Archer
    Department of Microbiology, University of Texas Health Science Center, San Antonio 78284, USA
    Virology 304:274-81. 2002
    ..The results imply that arenaviruses have been evolving independently for a very long time, leading to very diverse groupings that do not correlate with geography, rodent host, or human epidemic potential...

Research Grants1

  1. Dengue Virus Determinants of Virulence and Transmission
    Rebeca Rico Hesse; Fiscal Year: 2009
    ..Hypothesis: Aedes aegypti saliva facilitates and/or potentiates dengue virus infection of initial target (dendritic) cells. ..