John P Hanrahan

Summary

Affiliation: Sepracor Inc
Country: USA

Publications

  1. doi request reprint Effect of nebulized arformoterol on airway function in COPD: results from two randomized trials
    John P Hanrahan
    Sepracor Inc, Marlborough, MA 01752, USA
    COPD 5:25-34. 2008
  2. ncbi request reprint Nebulized arformoterol in patients with COPD: a 12-week, multicenter, randomized, double-blind, double-dummy, placebo- and active-controlled trial
    Rudolf A Baumgartner
    Sepracor Inc, Marlborough, Massachusetts 01752, USA
    Clin Ther 29:261-78. 2007
  3. doi request reprint A cumulative dose study of levalbuterol and racemic albuterol administered by hydrofluoroalkane-134a metered-dose inhaler in asthmatic subjects
    Kenneth Tripp
    Sepracor, Inc, Marlborough, MA 01752, USA
    J Allergy Clin Immunol 122:544-9. 2008
  4. doi request reprint Arrhythmias in patients with chronic obstructive pulmonary disease (COPD): occurrence frequency and the effect of treatment with the inhaled long-acting beta2-agonists arformoterol and salmeterol
    John P Hanrahan
    Sepracor Inc, Marlborough, Massachusetts 01752, USA
    Medicine (Baltimore) 87:319-28. 2008
  5. ncbi request reprint The influence of breathing pattern during nebulization on the delivery of arformoterol using a breath simulator
    Andrea Bauer
    Aerosol Development, Sepracor, 84 Waterford Drive, Marlborough MA 01752, USA
    Respir Care 54:1488-92. 2009
  6. ncbi request reprint Output and aerosol properties of 5 nebulizer/compressor systems with arformoterol inhalation solution
    Andrea Bauer
    Aerosol Development, Sepracor, 84 Waterford Drive, Marlborough, MA 01752, USA
    Respir Care 54:1342-7. 2009
  7. ncbi request reprint A comparison of levalbuterol with racemic albuterol in the treatment of acute severe asthma exacerbations in adults
    Richard Nowak
    Department of Emergency Medicine, Henry Ford Hospital, Detroit, MI, USA
    Am J Emerg Med 24:259-67. 2006
  8. pmc ARG1 is a novel bronchodilator response gene: screening and replication in four asthma cohorts
    Augusto A Litonjua
    Channing Laboratory, Pulmonary Division, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Am J Respir Crit Care Med 178:688-94. 2008
  9. pmc Association of corticotropin-releasing hormone receptor-2 genetic variants with acute bronchodilator response in asthma
    Audrey H Poon
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Pharmacogenet Genomics 18:373-82. 2008
  10. ncbi request reprint A comparison of 5-day courses of dirithromycin and azithromycin in the treatment of acute exacerbations of chronic obstructive pulmonary disease
    Richard S Castaldo
    SUNY Buffalo School of Medicine, Buffalo, New York, USA
    Clin Ther 25:542-57. 2003

Collaborators

Detail Information

Publications10

  1. doi request reprint Effect of nebulized arformoterol on airway function in COPD: results from two randomized trials
    John P Hanrahan
    Sepracor Inc, Marlborough, MA 01752, USA
    COPD 5:25-34. 2008
    ..Arformoterol, a single isomer long-acting beta(2)-agonist, was developed as an inhalation solution for the maintenance treatment of bronchoconstriction in COPD...
  2. ncbi request reprint Nebulized arformoterol in patients with COPD: a 12-week, multicenter, randomized, double-blind, double-dummy, placebo- and active-controlled trial
    Rudolf A Baumgartner
    Sepracor Inc, Marlborough, Massachusetts 01752, USA
    Clin Ther 29:261-78. 2007
    ....
  3. doi request reprint A cumulative dose study of levalbuterol and racemic albuterol administered by hydrofluoroalkane-134a metered-dose inhaler in asthmatic subjects
    Kenneth Tripp
    Sepracor, Inc, Marlborough, MA 01752, USA
    J Allergy Clin Immunol 122:544-9. 2008
    ..The short-acting beta(2)-agonists levalbuterol and racemic albuterol are available for administration through a hydrofluoroalkane-134a (HFA) metered-dose inhaler (MDI)...
  4. doi request reprint Arrhythmias in patients with chronic obstructive pulmonary disease (COPD): occurrence frequency and the effect of treatment with the inhaled long-acting beta2-agonists arformoterol and salmeterol
    John P Hanrahan
    Sepracor Inc, Marlborough, Massachusetts 01752, USA
    Medicine (Baltimore) 87:319-28. 2008
    ..More serious arrhythmias were infrequent and did not increase with inhaled LABA therapy. LABA administration did not increase mean heart rate...
  5. ncbi request reprint The influence of breathing pattern during nebulization on the delivery of arformoterol using a breath simulator
    Andrea Bauer
    Aerosol Development, Sepracor, 84 Waterford Drive, Marlborough MA 01752, USA
    Respir Care 54:1488-92. 2009
    ..This in vitro study evaluated whether different tidal breathing patterns that encompass a range that could be observed in COPD patients influence the emitted amount of nebulized arformoterol...
  6. ncbi request reprint Output and aerosol properties of 5 nebulizer/compressor systems with arformoterol inhalation solution
    Andrea Bauer
    Aerosol Development, Sepracor, 84 Waterford Drive, Marlborough, MA 01752, USA
    Respir Care 54:1342-7. 2009
    ..This study compared the aerosol properties of arformoterol delivered via 5 commonly used nebulizer systems for the home-care market...
  7. ncbi request reprint A comparison of levalbuterol with racemic albuterol in the treatment of acute severe asthma exacerbations in adults
    Richard Nowak
    Department of Emergency Medicine, Henry Ford Hospital, Detroit, MI, USA
    Am J Emerg Med 24:259-67. 2006
    ..This multicenter, randomized, double-blind trial compared nebulized levalbuterol (Lev) and racemic albuterol (Rac) in the treatment of acute asthma...
  8. pmc ARG1 is a novel bronchodilator response gene: screening and replication in four asthma cohorts
    Augusto A Litonjua
    Channing Laboratory, Pulmonary Division, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Am J Respir Crit Care Med 178:688-94. 2008
    ..However, a substantial proportion of patients with asthma do not have a favorable response to these drugs, and identifying genetic determinants of drug response may aid in tailoring treatment for individual patients...
  9. pmc Association of corticotropin-releasing hormone receptor-2 genetic variants with acute bronchodilator response in asthma
    Audrey H Poon
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Pharmacogenet Genomics 18:373-82. 2008
    ..We aim to assess associations between genetic variants of CRHR2 and acute bronchodilator response in asthma...
  10. ncbi request reprint A comparison of 5-day courses of dirithromycin and azithromycin in the treatment of acute exacerbations of chronic obstructive pulmonary disease
    Richard S Castaldo
    SUNY Buffalo School of Medicine, Buffalo, New York, USA
    Clin Ther 25:542-57. 2003
    ..The macrolide antibiotics, particularly second-generation agents such as dirithromycin and azithromycin, are among the antibiotic classes frequently recommended and used to treat upper and lower respiratory infections, including AECB...