Affiliation: Rutgers University
- Phosphatidylinositol 4-kinases: hostages harnessed to build panviral replication platformsNihal Altan-Bonnet
Host Pathogen Dynamics Group, Federated Department of Biological Sciences, Rutgers University, Newark, NJ, USA
Trends Biochem Sci 37:293-302. 2012..It explores the potential mechanisms by which PtdIns4P lipids can contribute to viral replication and discusses the therapeutic potential of developing antiviral molecules that target host PI4Ks as a form of panviral therapy...
- Enteroviruses harness the cellular endocytic machinery to remodel the host cell cholesterol landscape for effective viral replicationOlha Ilnytska
Laboratory of Host Pathogen Dynamics, Rutgers University, Newark, NJ 07102, USA
Cell Host Microbe 14:281-93. 2013..Our findings indicate cholesterol as a critical determinant for enteroviral replication and outline roles for the endocytic machinery in both the enteroviral life cycle and host cell cholesterol homeostasis...
- Phosphatidylserine vesicles enable efficient en bloc transmission of enterovirusesYing Han Chen
Laboratory of Host Pathogen Dynamics, National Heart Lung and Blood Institute, NIH, Bethesda, MD 20892, USA Federated Department of Biological Sciences, Rutgers University, Newark, NJ 07102, USA
Cell 160:619-30. 2015..This has implications for facilitating genetic cooperativity among viral quasispecies as well as enhancing viral replication...
- Viral reorganization of the secretory pathway generates distinct organelles for RNA replicationNai Yun Hsu
Department of Biological Sciences, Rutgers University, Newark, NJ 07102, USA
Cell 141:799-811. 2010..These findings reveal how RNA viruses can selectively exploit specific elements of the host to form specialized organelles where cellular phosphoinositide lipids are key to regulating viral RNA replication...