Ali Banan

Summary

Affiliation: Rush University Medical Center
Country: USA

Publications

  1. ncbi Key role of PKC and Ca2+ in EGF protection of microtubules and intestinal barrier against oxidants
    A Banan
    Department of Internal Medicine Division of Digestive Diseases, Rush University Medical Center, 1725 W Harrison, Suite 206, Chicago, IL 60612, USA
    Am J Physiol Gastrointest Liver Physiol 280:G828-43. 2001
  2. ncbi theta Isoform of protein kinase C alters barrier function in intestinal epithelium through modulation of distinct claudin isotypes: a novel mechanism for regulation of permeability
    A Banan
    Department of Internal Medicine, Rush University Medical Center, Chicago, IL 60612, USA
    J Pharmacol Exp Ther 313:962-82. 2005
  3. ncbi PKC-zeta prevents oxidant-induced iNOS upregulation and protects the microtubules and gut barrier integrity
    A Banan
    Department of Internal Medicine, Section of Gastroenterology and Nutrition, Rush University Medical Center, Chicago, Illinois 60612, USA
    Am J Physiol Gastrointest Liver Physiol 283:G909-22. 2002
  4. ncbi Activation of delta-isoform of protein kinase C is required for oxidant-induced disruption of both the microtubule cytoskeleton and permeability barrier of intestinal epithelia
    A Banan
    Department of Internal Medicine Section of Gastroenterology and Nutrition, Rush University Medical Center, Chicago, Illinois, USA
    J Pharmacol Exp Ther 303:17-28. 2002
  5. ncbi Novel effect of NF-kappaB activation: carbonylation and nitration injury to cytoskeleton and disruption of monolayer barrier in intestinal epithelium
    A Banan
    Rush University Medical Center, Department of Internal Medicine, Section of Gastroenterology and Nutrition, 1725 W Harrison, Suite 206, Chicago, IL 60612, USA
    Am J Physiol Cell Physiol 287:C1139-51. 2004
  6. ncbi The delta-isoform of protein kinase C causes inducible nitric-oxide synthase and nitric oxide up-regulation: key mechanism for oxidant-induced carbonylation, nitration, and disassembly of the microtubule cytoskeleton and hyperpermeability of barrier of in
    A Banan
    Department of Internal Medicine, Section of Gastroenterology and Nutrition, Pharmacology, and Molecular Physiology, Rush University of Chicago, 1725 W Harrison, Suite 206, Chicago, IL 60612, USA
    J Pharmacol Exp Ther 305:482-94. 2003
  7. ncbi Critical role of the atypical {lambda} isoform of protein kinase C (PKC-{lambda}) in oxidant-induced disruption of the microtubule cytoskeleton and barrier function of intestinal epithelium
    A Banan
    Section of Gastroenterology and Nutrition, Rush University of Chicago, College of Medicine, Division of Digestive Diseases, 1725 W Harrison, Suite 206, Chicago, IL 60612, USA
    J Pharmacol Exp Ther 312:458-71. 2005
  8. ncbi Theta-isoform of PKC is required for alterations in cytoskeletal dynamics and barrier permeability in intestinal epithelium: a novel function for PKC-theta
    A Banan
    Department of Internal Medicine, Rush University Medical Center, Chicago, IL 60612, USA
    Am J Physiol Cell Physiol 287:C218-34. 2004
  9. ncbi Key role of PLC-gamma in EGF protection of epithelial barrier against iNOS upregulation and F-actin nitration and disassembly
    A Banan
    Department of Internal Medicine, Section of Gastroenterology and Nutrition, Rush University School of Medicine, 1725 W Harrison, Suite 206, Chicago, IL 60612, USA
    Am J Physiol Cell Physiol 285:C977-93. 2003
  10. ncbi Inhibition of oxidant-induced nuclear factor-kappaB activation and inhibitory-kappaBalpha degradation and instability of F-actin cytoskeletal dynamics and barrier function by epidermal growth factor: key role of phospholipase-gamma isoform
    A Banan
    Division of Digestive Diseases, Department of Internal Medicine, Section of Gastroenterology and Nutrition, Rush University of Chicago School of Medicine, 1725 W Harrison, Suite 206, Chicago, IL 60612, USA
    J Pharmacol Exp Ther 309:356-68. 2004

Research Grants

Collaborators

Detail Information

Publications44

  1. ncbi Key role of PKC and Ca2+ in EGF protection of microtubules and intestinal barrier against oxidants
    A Banan
    Department of Internal Medicine Division of Digestive Diseases, Rush University Medical Center, 1725 W Harrison, Suite 206, Chicago, IL 60612, USA
    Am J Physiol Gastrointest Liver Physiol 280:G828-43. 2001
    ..In conclusion, EGF protection of microtubules and the intestinal epithelial barrier requires activation of PKC signal transduction and normalization of ([Ca2+](i))...
  2. ncbi theta Isoform of protein kinase C alters barrier function in intestinal epithelium through modulation of distinct claudin isotypes: a novel mechanism for regulation of permeability
    A Banan
    Department of Internal Medicine, Rush University Medical Center, Chicago, IL 60612, USA
    J Pharmacol Exp Ther 313:962-82. 2005
    ..The ability of PKC- to alter the dynamics of permeability protein claudins is a new function not previously ascribed to the novel subfamily of PKC isoforms...
  3. ncbi PKC-zeta prevents oxidant-induced iNOS upregulation and protects the microtubules and gut barrier integrity
    A Banan
    Department of Internal Medicine, Section of Gastroenterology and Nutrition, Rush University Medical Center, Chicago, Illinois 60612, USA
    Am J Physiol Gastrointest Liver Physiol 283:G909-22. 2002
    ..We have thus discovered novel biologic functions, suppression of the iNOS-driven reactions and cytoskeletal oxidation, among the atypical PKC isoforms...
  4. ncbi Activation of delta-isoform of protein kinase C is required for oxidant-induced disruption of both the microtubule cytoskeleton and permeability barrier of intestinal epithelia
    A Banan
    Department of Internal Medicine Section of Gastroenterology and Nutrition, Rush University Medical Center, Chicago, Illinois, USA
    J Pharmacol Exp Ther 303:17-28. 2002
    ..Thus, PKC-delta activation may play a key role in intestinal dysfunction in oxidant-induced diseases such as inflammatory bowel disease...
  5. ncbi Novel effect of NF-kappaB activation: carbonylation and nitration injury to cytoskeleton and disruption of monolayer barrier in intestinal epithelium
    A Banan
    Rush University Medical Center, Department of Internal Medicine, Section of Gastroenterology and Nutrition, 1725 W Harrison, Suite 206, Chicago, IL 60612, USA
    Am J Physiol Cell Physiol 287:C1139-51. 2004
    ..The ability to promote NO overproduction and cytoskeletal nitration/oxidation is a novel mechanism not previously attributed to NF-kappaB in cells...
  6. ncbi The delta-isoform of protein kinase C causes inducible nitric-oxide synthase and nitric oxide up-regulation: key mechanism for oxidant-induced carbonylation, nitration, and disassembly of the microtubule cytoskeleton and hyperpermeability of barrier of in
    A Banan
    Department of Internal Medicine, Section of Gastroenterology and Nutrition, Pharmacology, and Molecular Physiology, Rush University of Chicago, 1725 W Harrison, Suite 206, Chicago, IL 60612, USA
    J Pharmacol Exp Ther 305:482-94. 2003
    ..3) We thus report a pathophysiological mechanism, activation of iNOS pathway and its injurious consequences to the cytoskeleton, including oxidation and nitration, among the "novel" subfamily of PKC isoforms...
  7. ncbi Critical role of the atypical {lambda} isoform of protein kinase C (PKC-{lambda}) in oxidant-induced disruption of the microtubule cytoskeleton and barrier function of intestinal epithelium
    A Banan
    Section of Gastroenterology and Nutrition, Rush University of Chicago, College of Medicine, Division of Digestive Diseases, 1725 W Harrison, Suite 206, Chicago, IL 60612, USA
    J Pharmacol Exp Ther 312:458-71. 2005
    ..The unique ability to mediate an oxidant-like injury and cytoskeletal depolymerization and instability is a novel mechanism not previously attributed to the atypical subfamily of PKC isoforms...
  8. ncbi Theta-isoform of PKC is required for alterations in cytoskeletal dynamics and barrier permeability in intestinal epithelium: a novel function for PKC-theta
    A Banan
    Department of Internal Medicine, Rush University Medical Center, Chicago, IL 60612, USA
    Am J Physiol Cell Physiol 287:C218-34. 2004
    ..The ability to alter the cytoskeletal and barrier dynamics is a unique function not previously attributed to PKC-theta...
  9. ncbi Key role of PLC-gamma in EGF protection of epithelial barrier against iNOS upregulation and F-actin nitration and disassembly
    A Banan
    Department of Internal Medicine, Section of Gastroenterology and Nutrition, Rush University School of Medicine, 1725 W Harrison, Suite 206, Chicago, IL 60612, USA
    Am J Physiol Cell Physiol 285:C977-93. 2003
    ....
  10. ncbi Inhibition of oxidant-induced nuclear factor-kappaB activation and inhibitory-kappaBalpha degradation and instability of F-actin cytoskeletal dynamics and barrier function by epidermal growth factor: key role of phospholipase-gamma isoform
    A Banan
    Division of Digestive Diseases, Department of Internal Medicine, Section of Gastroenterology and Nutrition, Rush University of Chicago School of Medicine, 1725 W Harrison, Suite 206, Chicago, IL 60612, USA
    J Pharmacol Exp Ther 309:356-68. 2004
    ....
  11. ncbi Zeta isoform of protein kinase C prevents oxidant-induced nuclear factor-kappaB activation and I-kappaBalpha degradation: a fundamental mechanism for epidermal growth factor protection of the microtubule cytoskeleton and intestinal barrier integrity
    A Banan
    Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA
    J Pharmacol Exp Ther 307:53-66. 2003
    ..To our knowledge, this is the first report that PKC-zeta can inhibit the dynamics of NF-kappaB and cytoskeletal disassembly in cells...
  12. ncbi The beta 1 isoform of protein kinase C mediates the protective effects of epidermal growth factor on the dynamic assembly of F-actin cytoskeleton and normalization of calcium homeostasis in human colonic cells
    Ali Banan
    Department of Internal Medicine, Section of Gastroenterology and Nutrition, Rush University Medical Center, 1725 West Harrison, Chicago, IL 60612, USA
    J Pharmacol Exp Ther 301:852-66. 2002
    ..EGF normalizes Ca(2+) by enhancing Ca(2+) efflux through PKC-beta1. We have identified novel biologic functions, protection of actin and Ca(2+) homeostasis, among the classical isoforms of PKC...
  13. ncbi PKC-zeta is required in EGF protection of microtubules and intestinal barrier integrity against oxidant injury
    A Banan
    Department of Internal Medicine, Division of Digestive Diseases, Rush University Medical Center, Chicago, Illinois 60612, USA
    Am J Physiol Gastrointest Liver Physiol 282:G794-808. 2002
    ....
  14. ncbi PKC-beta1 isoform activation is required for EGF-induced NF-kappaB inactivation and IkappaBalpha stabilization and protection of F-actin assembly and barrier function in enterocyte monolayers
    A Banan
    Division of Digestive Diseases, Department of Internal Medicine, Department of Pharmacology, and Department of Molecular Physiology, Rush University Medical Center, Chicago, Illinois 60612, USA
    Am J Physiol Cell Physiol 286:C723-38. 2004
    ..The ability to inhibit the dynamics of NF-kappaB/IkappaBalpha and F-actin disassembly is a novel mechanism not previously attributed to the classic subfamily of PKC isoforms...
  15. pmc Carbonylation and disassembly of the F-actin cytoskeleton in oxidant induced barrier dysfunction and its prevention by epidermal growth factor and transforming growth factor alpha in a human colonic cell line
    A Banan
    Division of Digestive Disease, Rush University Medical Center, Department of Internal Medicine, Chicago, Illinois, USA
    Gut 46:830-7. 2000
    ..However, the underlying mechanisms of oxidant induced disruption and growth factor mediated protection remain elusive...
  16. ncbi Nitric oxide and its metabolites mediate ethanol-induced microtubule disruption and intestinal barrier dysfunction
    A Banan
    Department of Internal Medicine Division of Digestive Diseases, Pharmacology, and Molecular Biophysics and Physiology, Rush University Medical Center, Chicago, IL 60612, USA
    J Pharmacol Exp Ther 294:997-1008. 2000
    ..These findings provide a rationale for the development of novel therapeutic agents for alcohol-induced GI disorders that inhibit this mechanism...
  17. ncbi OPC-compounds prevent oxidant-induced carbonylation and depolymerization of the F-actin cytoskeleton and intestinal barrier hyperpermeability
    A Banan
    Departments of Internal Medicine Division of Digestive Diseases, Pharmacology, and Molecular Biophysics and Physiology, Rush University Medical Center, 1725 W Harrison, Chicago, IL 60612, USA
    Free Radic Biol Med 30:287-98. 2001
    ..Accordingly, these compounds may be used as novel therapeutic agents for the treatment of a variety of oxidative inflammatory intestinal disorders with an abnormal mucosal barrier such as inflammatory bowel disease...
  18. ncbi Evidence that nuclear factor-kappa B activation is critical in oxidant-induced disruption of the microtubule cytoskeleton and barrier integrity and that its inactivation is essential in epidermal growth factor-mediated protection of the monolayers of inte
    A Banan
    Department of Internal Medicine, Section of Gastroenterology and Nutrition, Rush University Medical Center, Chicago, IL 60612, USA
    J Pharmacol Exp Ther 306:13-28. 2003
    ..To our knowledge, this is the first report that NF-kappaB can affect the dynamics of cytoskeletal assembly and intestinal barrier integrity...
  19. ncbi iNOS upregulation mediates oxidant-induced disruption of F-actin and barrier of intestinal monolayers
    A Banan
    Division of Digestive Diseases, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois 60612, USA
    Am J Physiol Gastrointest Liver Physiol 280:G1234-46. 2001
    ..Confirming these mechanisms in vivo would provide a rationale for developing novel anti-RNM therapies for IBD...
  20. ncbi Phospholipase C-gamma inhibition prevents EGF protection of intestinal cytoskeleton and barrier against oxidants
    A Banan
    Division of Digestive Diseases, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois 60612, USA
    Am J Physiol Gastrointest Liver Physiol 281:G412-23. 2001
    ..Transfected cells also lost EGF protection and showed reduced PLC-gamma phosphorylation and activity. We conclude that EGF protection requires PLC-gamma signaling and that PLC-gamma may be a useful therapeutic target...
  21. ncbi PKC-beta1 mediates EGF protection of microtubules and barrier of intestinal monolayers against oxidants
    A Banan
    Division of Digestive Diseases, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois 60612, USA
    Am J Physiol Gastrointest Liver Physiol 281:G833-47. 2001
    ..This mechanism may be useful for development of novel therapies for the treatment of inflammatory gastrointestinal disorders including inflammatory bowel disease...
  22. ncbi NF-kappaB activation as a key mechanism in ethanol-induced disruption of the F-actin cytoskeleton and monolayer barrier integrity in intestinal epithelium
    A Banan
    Department of Internal Medicine, Section of Gastroenterology and Nutrition, Rush University Medical Center, Chicago, IL 60612, USA
    Alcohol 41:447-60. 2007
    ....
  23. pmc Oats supplementation prevents alcohol-induced gut leakiness in rats by preventing alcohol-induced oxidative tissue damage
    Yueming Tang
    Division of Digestive Disease and Nutrition, Department of Internal Medicine, Rush University, Chicago, IL, USA
    J Pharmacol Exp Ther 329:952-8. 2009
    ..This study suggests that oats may be a useful therapeutic agent--a nutraceutical--for the prevention of alcohol-induced oxidative stress and organ dysfunction...
  24. ncbi Evidence for non-chemical, non-electrical intercellular signaling in intestinal epithelial cells
    Ashkan Farhadi
    Section of Gastroenterology and Nutrition, Rush University Medical Center, Chicago, IL 60612, USA
    Bioelectrochemistry 71:142-8. 2007
    ..This signaling system possibly plays a role in synchronous, stimulus-appropriate cell responses to noxious stimuli and may explain a number of cellular behaviors that are hard to explain based only on conventional cell signaling systems...
  25. pmc Nitric oxide-mediated intestinal injury is required for alcohol-induced gut leakiness and liver damage
    Yueming Tang
    Department of Internal Medicine, Division of Digestive Diseases and Nutrition, Rush University, Chicago, Illinois, USA
    Alcohol Clin Exp Res 33:1220-30. 2009
    ..We hypothesized that iNOS inhibitors [NG-nitro-l-arginine methyl ester (l-NAME), l-N(6)-(1-iminoethyl)-lysine (l-NIL)] in vivo will inhibit the above cascade and liver injury in an animal model of alcoholic steatohepatitis (ASH)...
  26. ncbi Ethanol-induced barrier dysfunction and its prevention by growth factors in human intestinal monolayers: evidence for oxidative and cytoskeletal mechanisms
    A Banan
    Division of Digestive Disease, Rush University Medical Center, Department of Internal Medicine, Chicago, Illinois 60612, USA
    J Pharmacol Exp Ther 291:1075-85. 1999
    ..Protection by EGF and TGF-alpha involves the prevention of these EtOH-induced alterations in microtubules...
  27. pmc Evidence that chronic alcohol exposure promotes intestinal oxidative stress, intestinal hyperpermeability and endotoxemia prior to development of alcoholic steatohepatitis in rats
    Ali Keshavarzian
    Department of Internal Medicine, Division of Digestive Disease and Nutrition, Rush University Medical Center, Chicago, IL 60612, USA
    J Hepatol 50:538-47. 2009
    ..Accordingly, the aim of the current study was to determine whether endotoxemia occurs prior to development of ASH and whether gut leakiness is the primary cause of the endotoxemia in an animal model of ASH...
  28. ncbi Effect of alcohol on miR-212 expression in intestinal epithelial cells and its potential role in alcoholic liver disease
    Yueming Tang
    Division of Digestive Disease and Nutrition, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois 60612, USA
    Alcohol Clin Exp Res 32:355-64. 2008
    ..Zonula occludens 1 (ZO-1) protein is a major component of tight junctions that regulates intestinal permeability. microRNAs (miRNAs) are recently discovered regulatory molecules that inhibit expression of their target genes...
  29. ncbi Reduced immunostaining for c-kit receptors in mucosal mast cells in inflammatory bowel disease
    Ashkan Farhadi
    Section of Gastroenterology and Nutrition, and Department of Molecular Biophysics and Physiology, Rush University Medical Center, Chicago, Illinois 60612, USA
    J Gastroenterol Hepatol 22:2338-43. 2007
    ..This increased activation of MC in IBD could be due to (i) greater activation of the BGA or (ii) inherited or acquired abnormalities in mucosal MC. In the current study we investigated the latter possibility...
  30. ncbi Intestinal barrier: an interface between health and disease
    Ashkan Farhadi
    Department of Internal Medicine Section of Gastroenterology and Nutrition, Rush University Medical Center, Chicago, Illinois 60612, USA
    J Gastroenterol Hepatol 18:479-97. 2003
    ....
  31. ncbi Heightened responses to stressors in patients with inflammatory bowel disease
    Ashkan Farhadi
    Department of Internal Medicine, Section of Gastroenterology and Nutrition, Rush University Medical Center, Chicago, Illinois 60612, USA
    Am J Gastroenterol 100:1796-804. 2005
    ..To test this hypothesis, we determined whether stressor-induced activation of BGA is exaggerated in IBD patients...
  32. ncbi Gas chromatographic method for detection of urinary sucralose: application to the assessment of intestinal permeability
    Ashkan Farhadi
    Department of Internal Medicine, Division of Digestive Diseases, Rush University Medical Center, 60612, Chicago, IL, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 784:145-54. 2003
    ..Thus, the 24-h urinary concentrations of S and M, or the urinary S/M ratio following an oral dose of a sugar mixture, might be good markers for whole gut permeability...
  33. ncbi Resolution of common dietary sugars from probe sugars for test of intestinal permeability using capillary column gas chromatography
    Ashkan Farhadi
    Department of Internal Medicine, Section of Gastroenterology and Nutrition, Rush University Medical Center, Chicago, IL 60612, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 836:63-8. 2006
    ..The most-widely used sugar probes are sucrose, lactulose, mannitol and sucralose. Measuring these sugars using a sensitive gas chromatographic (GC) method, we noticed interference on the area of the lactulose and mannitol peaks...
  34. ncbi Use of herbal preparations in the treatment of oxidant-mediated inflammatory disorders
    Mitchell Kaplan
    Rush University Medical Center, Department of Internal Medicine, Section of Gastroenterology and Nutrition, 1725 West Harrison Street, Suite 206, Chicago, IL 60612 3824, United States
    Complement Ther Med 15:207-16. 2007
    ....
  35. ncbi Oxidant-induced intestinal barrier disruption and its prevention by growth factors in a human colonic cell line: role of the microtubule cytoskeleton
    A Banan
    Division of Digestive Disease, Rush University Medical Center, Department of Internal Medicine, Chicago, IL 60612, USA
    Free Radic Biol Med 28:727-38. 2000
    ..Therefore, microtubules may be useful targets for development of drugs for the treatment of IBD...
  36. ncbi Preventing gut leakiness by oats supplementation ameliorates alcohol-induced liver damage in rats
    A Keshavarzian
    Section of Gastroenterology and Nutrition, Division of Digestive Diseases, Department of Internal Medicine, Rush Presbyterian St Lukes Medical Center, Chicago, Illinois 60612, USA
    J Pharmacol Exp Ther 299:442-8. 2001
    ..Further studies are needed to determine whether ALD in humans can be prevented by preventing alcohol-induced gut leakiness, studies that should lead to the development of useful therapeutic agents for the prevention of ALD...
  37. ncbi Regulation of oxidant-induced intestinal permeability by metalloprotease-dependent epidermal growth factor receptor signaling
    C B Forsyth
    Department of Internal Medicine, Section of Gastroenterology, Rush University Medical Center, 1725 W Harrison, Suite 206, Chicago, IL 60612, USA
    J Pharmacol Exp Ther 321:84-97. 2007
    ..These data could have a significant effect on our view of IBD pathogenesis and provide new therapeutic targets for IBD treatment...
  38. ncbi The role of protein kinase C isoforms in modulating injury and repair of the intestinal barrier
    A Farhadi
    Section of Gastroenterology and Nutrition, Division of Digestive Diseases, Rush University Medical Center, 1725 W Harrison, Suite 206, Chicago, IL 60612, USA
    J Pharmacol Exp Ther 316:1-7. 2006
    ....
  39. ncbi Modulatory effects of plasma and colonic milieu of patients with ulcerative colitis on neutrophil reactive oxygen species production in presence of a novel antioxidant, rebamipide
    A Farhadi
    Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois 60612, USA
    Dig Dis Sci 47:1342-8. 2002
    ....
  40. pmc Increases in free radicals and cytoskeletal protein oxidation and nitration in the colon of patients with inflammatory bowel disease
    A Keshavarzian
    Department of Internal Medicine Division of Digestive Diseases, Pharmacology, and Molecular Physiology, Rush University Medical Center, Chicago, IL 60612, USA
    Gut 52:720-8. 2003
    ..Our recent findings using monolayers of intestinal cells suggest that the mechanism could be oxidant induced damage to cytoskeletal proteins. However, oxidants and oxidative damage have not been well characterised in IBD mucosa...
  41. ncbi Phosphodiesterase 4 inhibitors and inflammatory bowel disease: emerging therapies in inflammatory bowel disease
    Ali Keshavarzian
    Rush University Medical Center, Department of Internal Medicine Division of Digestive Disease, Pharmacology, Physiology and Molecular Biophysics, Chicago, IL 60612, USA
    Expert Opin Investig Drugs 16:1489-506. 2007
    ..The authors detail the clinical development of the compound and report and provide insight into some of the unpublished data from the recently completed multicenter Phase III trials in UC...
  42. ncbi Novel antioxidants zolimid and AEOL11201 ameliorate colitis in rats
    S Choudhary
    Department of Medicine Rush Presbyterian St Lukes Medical Center, Chicago, Illinois 60612, USA
    Dig Dis Sci 46:2222-30. 2001
    ..In conclusion, Zolimid and AEOL11201 are effective antiinflammatory agents in an animal model of colitis. Further studies are needed to evaluate their beneficial therapeutic effects in patients with UC...
  43. ncbi Reactive oxygen species: are they involved in the pathogenesis of GERD, Barrett's esophagus, and the latter's progression toward esophageal cancer?
    Ashkan Farhadi
    Department of Medicine, Rush University Medical Center, Chicago, Illinois 60612, USA
    Am J Gastroenterol 97:22-6. 2002
  44. ncbi Exposure to ethanol induces oxidative damage in the pituitary gland
    Jian Ching Ren
    The Neuroscience Program, Loyola University Medical Center, Maywood, IL 60153, USA
    Alcohol 35:91-101. 2005
    ..These results provide evidence for ethanol-induced oxidative damage at the pituitary level, which may contribute to pituitary dysfunction...

Research Grants2

  1. EGF, Oxidants & Intestinal Barrier Integrity
    Ali Banan; Fiscal Year: 2006
    ..abstract_text> ..
  2. Protective Mechanism of an Anti-Inflammatory Herbal Mix
    Ali Banan; Fiscal Year: 2006
    ..abstract_text> ..