Song Yao

Summary

Affiliation: Roswell Park Cancer Institute
Country: USA

Publications

  1. pmc Bone remodeling and regulating biomarkers in women at the time of breast cancer diagnosis
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY, 14263, USA
    Breast Cancer Res Treat . 2016
  2. pmc Combined effects of circulating levels of 25-hydroxyvitamin d and Th1 and th2 cytokines on breast cancer estrogen receptor status
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Cancers (Basel) 6:211-25. 2014
  3. pmc Genetic variants in microRNAs and breast cancer risk in African American and European American women
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY, USA
    Breast Cancer Res Treat 141:447-59. 2013
  4. pmc Variants in the vitamin D pathway, serum levels of vitamin D, and estrogen receptor negative breast cancer among African-American women: a case-control study
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    Breast Cancer Res 14:R58. 2012
  5. pmc Manganese superoxide dismutase polymorphism, treatment-related toxicity and disease-free survival in SWOG 8897 clinical trial for breast cancer
    Song Yao
    Department of Cancer and Prevention and Control, Roswell Park Cancer Institute, Elm and Carlton Sts, Buffalo, NY 14263, USA
    Breast Cancer Res Treat 124:433-9. 2010
  6. pmc Gene polymorphisms in cyclophosphamide metabolism pathway,treatment-related toxicity, and disease-free survival in SWOG 8897 clinical trial for breast cancer
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Clin Cancer Res 16:6169-76. 2010
  7. pmc Pretreatment serum concentrations of 25-hydroxyvitamin D and breast cancer prognostic characteristics: a case-control and a case-series study
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York, United States of America
    PLoS ONE 6:e17251. 2011
  8. pmc Cytokine and cytokine receptor genes of the adaptive immune response are differentially associated with breast cancer risk in American women of African and European ancestry
    Lei Quan
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY
    Int J Cancer 134:1408-21. 2014
  9. pmc Common genetic variants are associated with accelerated bone mineral density loss after hematopoietic cell transplantation
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York, United States of America
    PLoS ONE 6:e25940. 2011
  10. pmc Genetic variations in vitamin D-related pathways and breast cancer risk in African American women in the AMBER consortium
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY
    Int J Cancer 138:2118-26. 2016

Detail Information

Publications35

  1. pmc Bone remodeling and regulating biomarkers in women at the time of breast cancer diagnosis
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY, 14263, USA
    Breast Cancer Res Treat . 2016
    ..Bone-related biomarkers at the time of breast cancer diagnosis may predict future risk of osteoporosis and fracture after endocrine therapy...
  2. pmc Combined effects of circulating levels of 25-hydroxyvitamin d and Th1 and th2 cytokines on breast cancer estrogen receptor status
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Cancers (Basel) 6:211-25. 2014
    ....
  3. pmc Genetic variants in microRNAs and breast cancer risk in African American and European American women
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY, USA
    Breast Cancer Res Treat 141:447-59. 2013
    ..Future studies are needed to validate our findings and to explore the underlying mechanisms. ..
  4. pmc Variants in the vitamin D pathway, serum levels of vitamin D, and estrogen receptor negative breast cancer among African-American women: a case-control study
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    Breast Cancer Res 14:R58. 2012
    ..We hypothesized that racial differences in 25OHD levels, as well as in inherited genetic variations, may contribute, in part, to the differences in tumor characteristics...
  5. pmc Manganese superoxide dismutase polymorphism, treatment-related toxicity and disease-free survival in SWOG 8897 clinical trial for breast cancer
    Song Yao
    Department of Cancer and Prevention and Control, Roswell Park Cancer Institute, Elm and Carlton Sts, Buffalo, NY 14263, USA
    Breast Cancer Res Treat 124:433-9. 2010
    ....
  6. pmc Gene polymorphisms in cyclophosphamide metabolism pathway,treatment-related toxicity, and disease-free survival in SWOG 8897 clinical trial for breast cancer
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Clin Cancer Res 16:6169-76. 2010
    ..In an ancillary study to a SWOG (Southwest Oncology Group) trial (S8897), we investigated functional polymorphisms in 4 genes in CP pharmacokinetic pathways in relation to hematologic toxicity and disease-free survival (DFS)...
  7. pmc Pretreatment serum concentrations of 25-hydroxyvitamin D and breast cancer prognostic characteristics: a case-control and a case-series study
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York, United States of America
    PLoS ONE 6:e17251. 2011
    ..Results from epidemiologic studies on the relationship between vitamin D and breast cancer risk are inconclusive. It is possible that vitamin D may be effective in reducing risk only of specific subtypes due to disease heterogeneity...
  8. pmc Cytokine and cytokine receptor genes of the adaptive immune response are differentially associated with breast cancer risk in American women of African and European ancestry
    Lei Quan
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY
    Int J Cancer 134:1408-21. 2014
    ..Our study systematically identified genetic variants in the adaptive immune response pathway associated with breast cancer risk, which appears to differ by ancestry groups, menopausal status and ER status...
  9. pmc Common genetic variants are associated with accelerated bone mineral density loss after hematopoietic cell transplantation
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York, United States of America
    PLoS ONE 6:e25940. 2011
    ..Hypothesizing that genetic variants may influence post-HCT BMD loss, we conducted a prospective study to examine the associations of single nucleotide polymorphisms (SNP) in bone metabolism pathways and acute BMD loss after HCT...
  10. pmc Genetic variations in vitamin D-related pathways and breast cancer risk in African American women in the AMBER consortium
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY
    Int J Cancer 138:2118-26. 2016
    ..In summary, several variants in vitamin D pathways were associated with breast cancer risk in AA women. In addition, CASR may be related to tumor ER status, supporting a role of vitamin D or calcium in modifying breast cancer phenotypes...
  11. pmc Innate immunity pathways and breast cancer Risk in African American and European-American women in the Women's Circle of Health Study (WCHS)
    Zhihong Gong
    Roswell Park Cancer Institute, Buffalo, New York, USA
    PLoS ONE 8:e72619. 2013
    ..These results suggest that immune adaptations suited to ancestral environments may differentially influence breast cancer risk among EA and AA women. ..
  12. pmc Repeat polymorphisms in estrogen metabolism genes and prostate cancer risk: results from the Prostate Cancer Prevention Trial
    Li Tang
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Carcinogenesis 32:1500-6. 2011
    ....
  13. doi request reprint Association of Serum Level of Vitamin D at Diagnosis With Breast Cancer Survival: A Case-Cohort Analysis in the Pathways Study
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York
    JAMA Oncol . 2016
    ..There are long-standing interests in the potential benefits of vitamin D for preventing breast cancer recurrence and mortality, yet data from prospective cohort studies are limited...
  14. pmc Important Role of Menarche in Development of Estrogen Receptor-Negative Breast Cancer in African American Women
    Christine B Ambrosone
    Roswell Park Cancer Institute, Buffalo, NY CBA, GZ, CCH, SY, DC University of North Carolina Lineberger Cancer Center, Chapel Hill, NC MAT, AFO Rutgers Cancer Institute of New Jersey, New Brunswick, NJ EVB Oregon Health and Science University, Portland, OR PS Slone Epidemiology Center at Boston University, Boston, MA TNB, LR, JRP University of Colorado Denver School of Medicine, Denver, CO VB University of Hawaii Cancer Center, Honolulu, HI SYP, LNK
    J Natl Cancer Inst 107:. 2015
    ..Menarche is a critical time point for diverging fates of mammary cells of origin. African American women have young age at menarche, which could be associated with their high rates of estrogen receptor-negative (ER-) breast cancer...
  15. pmc Genetic variants in one-carbon metabolism genes and breast cancer risk in European American and African American women
    Zhihong Gong
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY
    Int J Cancer 137:666-77. 2015
    ..0005) in EAs or AAs. In summary, our data suggest that one-carbon metabolizing gene polymorphisms could play a role in breast cancer and that may differ between EA and AA women. ..
  16. pmc Variants of estrogen-related genes and breast cancer risk in European and African American women
    Lei Quan
    Roswell Park Cancer InstituteElm and Carlton Streets, Buffalo, New York 14263, USAUniversity of Pittsburgh Cancer InstitutePittsburgh, Pennsylvania, USAIcahn School of Medicine at Mount SinaiNew York, New York, USANew Jersey Department of HealthTrenton, New Jersey, USARutgers Cancer Institute of New JerseyNew Brunswick, New Jersey, USA Roswell Park Cancer InstituteElm and Carlton Streets, Buffalo, New York 14263, USAUniversity of Pittsburgh Cancer InstitutePittsburgh, Pennsylvania, USAIcahn School of Medicine at Mount SinaiNew York, New York, USANew Jersey Department of HealthTrenton, New Jersey, USARutgers Cancer Institute of New JerseyNew Brunswick, New Jersey, USA
    Endocr Relat Cancer 21:853-64. 2014
    ..Future studies with a larger sample size may determine the full contribution of estrogen-related genes to racial/ethnic differences in breast cancer. ..
  17. pmc Genetic variants in the mTOR pathway and interaction with body size and weight gain on breast cancer risk in African-American and European American women
    Ting Yuan David Cheng
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Elm and Carlton Sts, Buffalo, NY, 14263, USA
    Cancer Causes Control 27:965-76. 2016
    ..As the obesity-breast cancer associations differ between European American (EA) and African-American (AA) women, we investigated genetic variants in the mTOR pathway and breast cancer risk in these two racial groups...
  18. pmc Trans-ethnic follow-up of breast cancer GWAS hits using the preferential linkage disequilibrium approach
    Qianqian Zhu
    Department of Biostatistics and Bioinformatics, Roswell Park Cancer Institute, Buffalo, NY, USA
    Oncotarget 7:83160-83176. 2016
    ..The results support trans-ethnic application of the preferential LD approach in search for candidate causal variants, and may have implications for future genetic research of breast cancer in AA women...
  19. pmc Genetic predictors of taxane-induced neurotoxicity in a SWOG phase III intergroup adjuvant breast cancer treatment trial (S0221)
    Lara E Sucheston
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Breast Cancer Res Treat 130:993-1002. 2011
    ..If replicated, women with these genotypes should be closely monitored for toxicities and could be targeted for preventive measures or alternative therapeutic approaches...
  20. pmc Genetic variations in the Hippo signaling pathway and breast cancer risk in African American women in the AMBER Consortium
    Jianmin Zhang
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Carcinogenesis 37:951-6. 2016
    ..05). In conclusion, common genetic variations in the Hippo signaling pathway may contribute to both ER-negative and ER+ breast cancer risk in AA women. ..
  21. pmc Associations between estrogen receptor-negative breast cancer and timing of reproductive events differ between African American and European American women
    Christine B Ambrosone
    Authors Affiliations Departments of Cancer Prevention and Control and Pathology, Roswell Park Cancer Institute, Buffalo Icahn School of Medicine at Mount Sinai, New York, New York University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania J Craig Venter Institute, Rockville, Maryland New Jersey State Cancer Registry, New Jersey Department of Health, Trenton Rutgers Cancer Institute of New Jersey, New Brunswick and Rutgers School of Public Health, Piscataway, New Jersey
    Cancer Epidemiol Biomarkers Prev 23:1115-20. 2014
    ..Cancer Epidemiol Biomarkers Prev; 23(6); 1115-20. ©2014 AACR. ..
  22. pmc Parity and breastfeeding among African-American women: differential effects on breast cancer risk by estrogen receptor status in the Women's Circle of Health Study
    Christine B Ambrosone
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Elm and Carlton Sts, Buffalo, NY, 14263, USA
    Cancer Causes Control 25:259-65. 2014
    ..We evaluated these associations in a case-control study among African-American women in New York City and New Jersey...
  23. doi request reprint Associations between vitamin D deficiency and risk of aggressive breast cancer in African-American women
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, United States
    J Steroid Biochem Mol Biol 136:337-41. 2013
    ..The relationship of vitamin D with breast cancer risk may be subtype-specific, with emerging evidence of stronger effects of vitamin D for more aggressive breast cancer, particularly in women of African ancestry...
  24. pmc Pretreatment levels of circulating Th1 and Th2 cytokines, and their ratios, are associated with ER-negative and triple negative breast cancers
    Chi Chen Hong
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Breast Cancer Res Treat 139:477-88. 2013
    ..19, 95 % CI 0.07-0.56). These findings indicate that immune function is associated with ER(-) and TNBC and may be most relevant among younger women, who are likely to be diagnosed with these aggressive phenotypes...
  25. doi request reprint Unrelated donor allogeneic hematopoietic cell transplantation is underused as a curative therapy in eligible patients from the United States
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York
    Biol Blood Marrow Transplant 19:1459-64. 2013
    ..Understanding the reasons for low use of alloHCT may lead to strategies to expand the use of this curative therapy for more patients with hematologic disorders. ..
  26. pmc Differences in somatic mutation landscape of hepatocellular carcinoma in Asian American and European American populations
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY, USA
    Oncotarget 7:40491-40499. 2016
    ..In conclusion, we demonstrated here mutational differences in important cancer genes and pathways between Asian and European ancestries. These differences may have implications for the prevention and treatment of HCC...
  27. doi request reprint Accelerated bone mineral density loss occurs with similar incidence and severity, but with different risk factors, after autologous versus allogeneic hematopoietic cell transplantation
    Song Yao
    Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Biol Blood Marrow Transplant 16:1130-7. 2010
    ..Evaluation of clinical strategies to prevent and reverse HCT-related BMD loss is necessary in both autologous and allogeneic HCT patients...
  28. ncbi request reprint Vegetable-derived isothiocyanates: anti-proliferative activity and mechanism of action
    Yuesheng Zhang
    Department of Chemoprevention, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Proc Nutr Soc 65:68-75. 2006
    ..Taken together, dietary ITC are highly-promising anti-cancer agents, capable of targetting multiple cellular components that are important for tumour cell survival and proliferation...
  29. pmc Case-only analyses of the associations between polymorphisms in the metastasis-modifying genes BRMS1 and SIPA1 and breast tumor characteristics, lymph node metastasis, and survival
    Michelle R Roberts
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    Breast Cancer Res Treat 139:873-85. 2013
    ..Future evaluation of metastasis-modifying gene variants is necessary to better understand the biology of metastasis. ..
  30. pmc Conducting Molecular Epidemiological Research in the Age of HIPAA: A Multi-Institutional Case-Control Study of Breast Cancer in African-American and European-American Women
    Christine B Ambrosone
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    J Oncol 2009:871250. 2009
    ....
  31. doi request reprint Cigarette smoking, N-acetyltransferase 2 genotypes, and breast cancer risk: pooled analysis and meta-analysis
    Christine B Ambrosone
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    Cancer Epidemiol Biomarkers Prev 17:15-26. 2008
    ..Because slow NAT2 genotypes are present in 50% to 60% of Caucasian populations, smoking is likely to play an important role in breast cancer etiology...
  32. doi request reprint A comparison of measured creatinine clearance versus calculated glomerular filtration rate for assessment of renal function before autologous and allogeneic BMT
    Theresa Hahn
    Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Biol Blood Marrow Transplant 15:574-9. 2009
    ..Larger analyses and transplantation of patients with GFR <50 mL/min may better define subgroups at risk for renal RRT...
  33. pmc The impact of DNA input amount and DNA source on the performance of whole-exome sequencing in cancer epidemiology
    Qianqian Zhu
    Department of Biostatistics and Bioinformatics, Roswell Park Cancer Institute, Buffalo, New York
    Cancer Epidemiol Biomarkers Prev 24:1207-13. 2015
    ..We evaluated the performance of WES with low input amount and saliva DNA as an alternative source material...
  34. pmc Serum estrogen levels and prostate cancer risk in the prostate cancer prevention trial: a nested case-control study
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY, USA
    Cancer Causes Control 22:1121-31. 2011
    ..Finasteride reduces prostate cancer risk by blocking the conversion of testosterone to dihydrotestosterone. However, whether finasteride affects estrogens levels or change in estrogens affects prostate cancer risk is unknown...
  35. ncbi request reprint c-jun/AP-1 activation does not affect the antiproliferative activity of phenethyl isothiocyanate, a cruciferous vegetable-derived cancer chemopreventive agent
    Song Yao
    Department of Chemoprevention, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Mol Carcinog 45:605-12. 2006
    ....