Hongkyun Kim

Summary

Affiliation: Rosalind Franklin University of Medicine and Science
Country: USA

Publications

  1. doi request reprint Protein Network Interacting with BK Channels
    H Kim
    Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL, United States Electronic address
    Int Rev Neurobiol 128:127-61. 2016
  2. pmc The dystrophin complex controls bk channel localization and muscle activity in Caenorhabditis elegans
    Hongkyun Kim
    Department of Cell Biology and Anatomy, The Chicago Medical School, Rosalind Franklin University of Science and Medicine, North Chicago, Illinois, United States of America
    PLoS Genet 5:e1000780. 2009
  3. pmc An alpha-catulin homologue controls neuromuscular function through localization of the dystrophin complex and BK channels in Caenorhabditis elegans
    Linu S Abraham
    Department of Cell Biology and Anatomy, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois, United States of America
    PLoS Genet 6:. 2010
  4. pmc Presynaptic BK channel localization is dependent on the hierarchical organization of alpha-catulin and dystrobrevin and fine-tuned by CaV2 calcium channels
    Kelly H Oh
    Department of Cell Biology and Anatomy, Chicago Medical School, Rosalind Franklin University, 60064, North Chicago, IL, USA
    BMC Neurosci 16:26. 2015
  5. pmc Reduced IGF signaling prevents muscle cell death in a Caenorhabditis elegans model of muscular dystrophy
    Kelly Hyunju Oh
    Department of Cell Biology and Anatomy, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064
    Proc Natl Acad Sci U S A 110:19024-9. 2013
  6. pmc An SLC6 transporter of the novel B(0,)- system aids in absorption and detection of nutrient amino acids in Caenorhabditis elegans
    Ryan Metzler
    The Department of Physiology and Biophysics of the Rosalind Franklin University of Medicine and Science, Chicago Medical School, North Chicago, IL 60064, USA
    J Exp Biol 216:2843-57. 2013
  7. pmc Computational Methods for Tracking, Quantitative Assessment, and Visualization of C. elegans Locomotory Behavior
    Kyle Moy
    School of Computing, College of Computing and Digital Media, DePaul University, Chicago, Illinois, United States of America
    PLoS ONE 10:e0145870. 2015
  8. pmc Interaction of α-catulin with dystrobrevin contributes to integrity of dystrophin complex in muscle
    Hyun J Oh
    Department of Cell Biology and Anatomy, Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064, USA
    J Biol Chem 287:21717-28. 2012

Collaborators

  • Kris Gevaert
  • MIRIAM GOODMAN
  • Linu S Abraham
  • Hyun J Oh
  • Jacob Furst
  • Daniela Raicu
  • Kyle Moy
  • Kelly H Oh
  • Kelly Hyunju Oh
  • Ryan Metzler
  • Evan Story
  • Yung Chi Huang
  • CHRISTOPHER BRANDON
  • Valerie Simonis
  • Christian Silvestri
  • Chandler Gegg
  • Weiyu Li
  • Mark J Alkema
  • Huu Phuoc Tran
  • JEFFREY FOX
  • Dmitri Y Boudko
  • Ella A Meleshkevitch
  • Christophe Stove
  • Joshua R Sanes
  • Frans van Roy
  • Joseph X DiMario
  • Jolanda van Hengel
  • Tomasz J Proszynski
  • Janet E Richmond
  • Feyza Sancar

Detail Information

Publications8

  1. doi request reprint Protein Network Interacting with BK Channels
    H Kim
    Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL, United States Electronic address
    Int Rev Neurobiol 128:127-61. 2016
    ..In this chapter, we review some of the relevant studies investigating the protein interaction network of BK channels with a focus on the biological roles of the interaction. ..
  2. pmc The dystrophin complex controls bk channel localization and muscle activity in Caenorhabditis elegans
    Hongkyun Kim
    Department of Cell Biology and Anatomy, The Chicago Medical School, Rosalind Franklin University of Science and Medicine, North Chicago, Illinois, United States of America
    PLoS Genet 5:e1000780. 2009
    ..Our results indicate that the DAPC modulates muscle excitability by localizing the SLO-1 channel to calcium-rich regions of C. elegans muscle...
  3. pmc An alpha-catulin homologue controls neuromuscular function through localization of the dystrophin complex and BK channels in Caenorhabditis elegans
    Linu S Abraham
    Department of Cell Biology and Anatomy, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois, United States of America
    PLoS Genet 6:. 2010
    ..Our results demonstrate that CTN-1 ensures the localization of SLO-1 within calcium nanodomains, thereby playing a crucial role in muscles and neurons...
  4. pmc Presynaptic BK channel localization is dependent on the hierarchical organization of alpha-catulin and dystrobrevin and fine-tuned by CaV2 calcium channels
    Kelly H Oh
    Department of Cell Biology and Anatomy, Chicago Medical School, Rosalind Franklin University, 60064, North Chicago, IL, USA
    BMC Neurosci 16:26. 2015
    ..However, the mechanism underlying BK channel localization near calcium channels is not fully understood...
  5. pmc Reduced IGF signaling prevents muscle cell death in a Caenorhabditis elegans model of muscular dystrophy
    Kelly Hyunju Oh
    Department of Cell Biology and Anatomy, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064
    Proc Natl Acad Sci U S A 110:19024-9. 2013
    ..Our study suggests that manipulation of the IGF signaling pathways in muscle cells could be a potent intervention for muscular dystrophy. ..
  6. pmc An SLC6 transporter of the novel B(0,)- system aids in absorption and detection of nutrient amino acids in Caenorhabditis elegans
    Ryan Metzler
    The Department of Physiology and Biophysics of the Rosalind Franklin University of Medicine and Science, Chicago Medical School, North Chicago, IL 60064, USA
    J Exp Biol 216:2843-57. 2013
    ..In addition to the predictable role in alimentary amino acid absorption, our results indicate possible neuronal roles of SNF-5 as an amino acid provider to specific neuronal functions, including sensing of amino acid availability. ..
  7. pmc Computational Methods for Tracking, Quantitative Assessment, and Visualization of C. elegans Locomotory Behavior
    Kyle Moy
    School of Computing, College of Computing and Digital Media, DePaul University, Chicago, Illinois, United States of America
    PLoS ONE 10:e0145870. 2015
    ..elegans can use Lévy flights for efficient food search. In summary, our tracker and analysis software will help analyze the neural basis of the alteration and transition of C. elegans locomotory behavior in a food-deprived condition. ..
  8. pmc Interaction of α-catulin with dystrobrevin contributes to integrity of dystrophin complex in muscle
    Hyun J Oh
    Department of Cell Biology and Anatomy, Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064, USA
    J Biol Chem 287:21717-28. 2012
    ..elegans and mammalian muscles and strongly suggests that this interaction contributes to the integrity of the dystrophin complex...

Research Grants1

  1. Identification of Novel Components of the Dystrophin Complex Using C. Elegans
    Hongkyun Kim; Fiscal Year: 2010
    ..We will also identify and study the functional mammalian homologues. These findings will improve our understanding of the pathogenesis mechanism of muscular dystrophy in humans and may help to devise new therapeutic strategies. ..