L W Yuan
Affiliation: Rainier Associates
- Phosphorylation of p300 at serine 89 by protein kinase CL W Yuan
Oregon Health Sciences University, Portland, Oregon 97201 and the Protein Structure Facility, Shriners Hospital for Children, Portland, Oregon 97201, USA
J Biol Chem 275:40946-51. 2000..This phosphorylation-mediated regulation of p300 function represents a previously unrecognized signal transduction pathway for protein kinase C to regulate cell growth and differentiation...
- Histone acetylation by p300 is involved in CREB-mediated transcription on chromatinL W Yuan
Oregon Health Sciences University, Portland 97298, USA
Biochim Biophys Acta 1541:161-9. 2001..Serine 133-phosphorylated CREB recruits p300 onto chromatin for efficient acetylation of nucleosomes. This targeted acetylation by p300 is essential to CREB-dependent transcription pathway...
- Inhibition of histone acetyltransferase function of p300 by PKCdeltaL W Yuan
Department of Physiology and Biophysics, School of Medicine, Boston University, 715 Albany St, MA 02118, USA
Biochim Biophys Acta 1592:205-11. 2002..These findings identify a new signal transduction pathway by which PKCdelta may inhibit cell growth and promote cellular differentiation...