Alistair P McGregor

Summary

Affiliation: Princeton University
Country: USA

Publications

  1. ncbi Morphological evolution through multiple cis-regulatory mutations at a single gene
    Alistair P McGregor
    Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey 08544, USA
    Nature 448:587-90. 2007
  2. doi Cupiennius salei and Achaearanea tepidariorum: Spider models for investigating evolution and development
    Alistair P McGregor
    Institute for Genetics, Evolutionary Genetics, University of Cologne, Koln, Germany
    Bioessays 30:487-98. 2008
  3. ncbi How to get ahead: the origin, evolution and function of bicoid
    Alistair P McGregor
    Department of Ecology and Evolutionary Biology, Princeton University, New Jersey 08540, USA
    Bioessays 27:904-13. 2005
  4. ncbi Wasps, beetles and the beginning of the ends
    Alistair P McGregor
    Department of Ecology and Evolutionary Biology, Guyot Hall, Princeton University, Princeton, New Jersey 08540, USA
    Bioessays 28:683-6. 2006
  5. pmc Shape and function of the Bicoid morphogen gradient in dipteran species with different sized embryos
    Thomas Gregor
    Howard Hughes Medical Institute, Princeton University, Princeton, NJ 08544, USA
    Dev Biol 316:350-8. 2008
  6. pmc Morphological evolution caused by many subtle-effect substitutions in regulatory DNA
    Nicolas Frankel
    Howard Hughes Medical Institute and Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey 08544, USA
    Nature 474:598-603. 2011
  7. pmc Stability and nuclear dynamics of the bicoid morphogen gradient
    Thomas Gregor
    Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey 08544, USA
    Cell 130:141-52. 2007
  8. ncbi Evolutionary and functional analysis of the tailless enhancer in Musca domestica and Drosophila melanogaster
    Naomi S Wratten
    Department of Genetics, University of Leicester, Leicester LE1 7RH, UK
    Evol Dev 8:6-15. 2006

Collaborators

Detail Information

Publications8

  1. ncbi Morphological evolution through multiple cis-regulatory mutations at a single gene
    Alistair P McGregor
    Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey 08544, USA
    Nature 448:587-90. 2007
    ..These data support the view that alleles of large effect that distinguish species may sometimes reflect the accumulation of multiple mutations of small effect at select genes...
  2. doi Cupiennius salei and Achaearanea tepidariorum: Spider models for investigating evolution and development
    Alistair P McGregor
    Institute for Genetics, Evolutionary Genetics, University of Cologne, Koln, Germany
    Bioessays 30:487-98. 2008
    ..We suggest that further comparisons between these two spiders and other chelicerates will prove useful for understanding the evolution of development in metazoans...
  3. ncbi How to get ahead: the origin, evolution and function of bicoid
    Alistair P McGregor
    Department of Ecology and Evolutionary Biology, Princeton University, New Jersey 08540, USA
    Bioessays 27:904-13. 2005
    ..I suggest further comparative studies may allow us to identify the intermediate steps in bcd evolution. This will make bcd a paradigm for the origin and evolution of genes and regulatory networks...
  4. ncbi Wasps, beetles and the beginning of the ends
    Alistair P McGregor
    Department of Ecology and Evolutionary Biology, Guyot Hall, Princeton University, Princeton, New Jersey 08540, USA
    Bioessays 28:683-6. 2006
    ....
  5. pmc Shape and function of the Bicoid morphogen gradient in dipteran species with different sized embryos
    Thomas Gregor
    Howard Hughes Medical Institute, Princeton University, Princeton, NJ 08544, USA
    Dev Biol 316:350-8. 2008
    ..However, a shallow gradient was observed using eGFP-NLS, suggesting nuclear localization may be necessary but not sufficient for gradient formation...
  6. pmc Morphological evolution caused by many subtle-effect substitutions in regulatory DNA
    Nicolas Frankel
    Howard Hughes Medical Institute and Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey 08544, USA
    Nature 474:598-603. 2011
    ..These data provide unprecedented resolution of the phenotypic effects of substitutions and show how individual nucleotide changes in a transcriptional enhancer have caused morphological evolution...
  7. pmc Stability and nuclear dynamics of the bicoid morphogen gradient
    Thomas Gregor
    Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey 08544, USA
    Cell 130:141-52. 2007
    ..A new model is presented emphasizing the possible role of nuclear dynamics in shaping and scaling the gradient...
  8. ncbi Evolutionary and functional analysis of the tailless enhancer in Musca domestica and Drosophila melanogaster
    Naomi S Wratten
    Department of Genetics, University of Leicester, Leicester LE1 7RH, UK
    Evol Dev 8:6-15. 2006
    ..Therefore, during the rapid evolution of enhancer sequences individual binding sites are continually lost and gained, but the transcriptional output is maintained by compensatory mutations in cis and in trans...