C M Trepod

Summary

Affiliation: Pharmacia and Upjohn
Country: USA

Publications

  1. ncbi request reprint Modification of the carboxy-terminal amino acid sequence alters the Escherichia coli expression of a gene encoding multiple repeats of a bovine growth hormone releasing factor analog
    C M Trepod
    Biology I, 7263 209 713, Pharmacia, Kalamazoo, MI 49007, USA
    J Biotechnol 84:273-84. 2000
  2. ncbi request reprint A spontaneous runaway vector for production-scale expression of bovine somatotropin from Escherichia coi
    C M Trepod
    Pharmacia, Infectious Diseases Biology, Kalamazoo, MI 49007, USA
    Appl Microbiol Biotechnol 58:84-8. 2002
  3. pmc Structural characterizations of nonpeptidic thiadiazole inhibitors of matrix metalloproteinases reveal the basis for stromelysin selectivity
    B C Finzel
    Structural, Analytical and Medicinal Chemistry, Pharmacia and Upjohn, Kalamazoo, Michigan 49007, USA
    Protein Sci 7:2118-26. 1998

Detail Information

Publications3

  1. ncbi request reprint Modification of the carboxy-terminal amino acid sequence alters the Escherichia coli expression of a gene encoding multiple repeats of a bovine growth hormone releasing factor analog
    C M Trepod
    Biology I, 7263 209 713, Pharmacia, Kalamazoo, MI 49007, USA
    J Biotechnol 84:273-84. 2000
    ..Negative extensions exert their influence through a more complex mechanism, appearing to interfere with the ability of ribosomes to be efficiently released from their cognate mRNA...
  2. ncbi request reprint A spontaneous runaway vector for production-scale expression of bovine somatotropin from Escherichia coi
    C M Trepod
    Pharmacia, Infectious Diseases Biology, Kalamazoo, MI 49007, USA
    Appl Microbiol Biotechnol 58:84-8. 2002
    ..Copy number analysis also confirmed the stability of pURA-4 spontaneous runaway from the shake-flask scale through the production scale...
  3. pmc Structural characterizations of nonpeptidic thiadiazole inhibitors of matrix metalloproteinases reveal the basis for stromelysin selectivity
    B C Finzel
    Structural, Analytical and Medicinal Chemistry, Pharmacia and Upjohn, Kalamazoo, Michigan 49007, USA
    Protein Sci 7:2118-26. 1998
    ..A conformational rearrangement of the catalytic domain occurs that reveals an inherent flexibility of the substrate binding region leading to speculation about a possible mechanism for modulation of stromelysin activity and selectivity...