Affiliation: Pfizer Global Research and Development
- Methods to determine the minimum important difference for a sexual event diary used by postmenopausal women with hypoactive sexual desire disorderTara Symonds
Pfizer Ltd, Kent, UK
J Sex Med 4:1328-35. 2007..There are issues with calculating an MID using each method: Will the two approaches give the same estimate? If the estimates differ, how do you decide on one estimate? Would asking patients directly be more beneficial?..
- Psychometric validation of a sexual quality of life questionnaire for use in men with premature ejaculation or erectile dysfunctionLucy Abraham
Global Outcomes Research, Pfizer Ltd, Sandwich, UK
J Sex Med 5:595-601. 2008..An instrument that can systematically capture the impact of sexual dysfunction on quality of life (QoL) in men is needed...
- Sexual function questionnaire: further refinement and validationTara Symonds
PRO Centre of Excellence, PCBU, Pfizer Ltd, Walton Oaks, Surrey, UK
J Sex Med 9:2609-16. 2012..The Sexual Function Questionnaire (SFQ) is a self-report outcome measure of female sexual function. It has recently been refined to create a 28-item version (SFQ28) including the addition of a new arousal-cognitive domain...
- Psychometric validation of gender nonspecific sexual confidence and sexual relationship scales in men and womenLucy Abraham
Global Outcomes Research, Pfizer Ltd, Sandwich, Kent, UK
J Sex Med 6:2244-54. 2009..The SCS assesses how confident an individual feels as a sexual partner, while the SRS assesses feelings that an individual has about their sexual relationship with their partner...
- A review of condition-specific instruments to assess the impact of urinary incontinence on health-related quality of lifeTara Symonds
Outcomes Research, Pfizer Global Research and Development, Sandwich Laboratories, Sandwich, Kent CT13 9NJ, UK
Eur Urol 43:219-25. 2003..Ten instruments were identified: general use (five); urinary urge (OAB) incontinence (four); and stress incontinence (one). Several were identified as valid instruments for assessing HRQoL in urinary incontinence patients...
- Development of a questionnaire on sexual quality of life in womenTara Symonds
Pfizer Global Research and Development, Sandwich, United Kingdom
J Sex Marital Ther 31:385-97. 2005..The SQOL-F is a valid instrument for assessing the impact of FSD on quality of life and as an adjunct in evaluating FSD in clinical trials. The SQOL-F sensitivity to changes in sexual function needs confirmation...
- Development and validation of a premature ejaculation diagnostic toolTara Symonds
Pfizer Ltd, Sandwich, Kent, UK
Eur Urol 52:565-73. 2007..Therefore, the aim was to develop a brief, multidimensional, psychometrically validated instrument for diagnosing PE status...
- The clinical significance of quality-of-life results: practical considerations for specific audiencesTara Symonds
Outcomes Research Department, Pfizer Ltd, Sandwich, Kent, United Kingdom
Mayo Clin Proc 77:572-83. 2002..Collectively, this series attempts to provide methods and means for making such determinations...
- Evaluating the sexual experience in men: validation of the sexual experience questionnaireJohn P Mulhall
Department of Urology, Weill Medical College of Cornell University, New York, NY, USA
J Sex Med 5:365-76. 2008..The absence of a single brief measure that assesses function and health-related quality of life (HRQoL) hinders evaluation of the sexual experience in men with erectile dysfunction (ED)...
- Estimation of a preference-based index from a condition-specific measure: the King's Health QuestionnaireJohn Brazier
Section of Health Economics and Decision Science, School of Health and Related Research, University of Sheffield, Sheffield, UK
Med Decis Making 28:113-26. 2008..Generic preference-based measures of health may not adequately cover the impact of some conditions. There is therefore increasing interest in developing condition-specific preference-based measures...
- Development and validation of the quality of erection questionnaireHartmut Porst
Private Practice of Urology Andrology, Hamburg, Germany
J Sex Med 4:372-81. 2007..There are no psychometrically validated assessment tools designed to solely and specifically evaluate satisfaction with the quality of erections...
- Patient reported outcomes used in the assessment of premature ejaculationStanley E Althof
Case Western Reserve University School of Medicine, Cleveland, OH, USA
Urol Clin North Am 34:581-9, vii. 2007..The authors hope this helps clinicians and researchers to identify brief, reliable, and valid measures that document treatment effects or identify men with PE...
- Development and validation of a new questionnaire to assess sexual satisfaction, control, and distress associated with premature ejaculationStanley Althof
Sex and Marital Therapy South Florida, West Palm Beach, FL, USA
J Sex Med 3:465-75. 2006..The objective of this study was to develop and validate a new questionnaire to measure the overall experience of PE...
- A methodology study to develop and validate a screener for hypoactive sexual desire disorder in postmenopausal womenSandra Leiblum
Center for Sexual and Relationship Health, Department of Psychiatry UMDNJ Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA
J Sex Med 3:455-64. 2006..A previous study reported validity and reliability of a structured diagnostic method created for clinical trials that can be performed in approximately 1 hour...
- A methodology study to validate a structured diagnostic method used to diagnose female sexual dysfunction and its subtypes in postmenopausal womenWulf H Utian
Department of Reproductive Biology, Case University, Cleveland, Ohio, USA
J Sex Marital Ther 31:271-83. 2005..The results showed that the method had good convergent validity and excellent intrarater reliability. Thus, we conclude that the SDM can reliably diagnose FSD status and FSD subtypes in postmenopausal women...
- Outcome measurement in female sexual dysfunction clinical trials: review and recommendationsStanley E Althof
Department of Urology, Case Western Reserve University School of Medicine, USA
J Sex Marital Ther 31:153-66. 2005..g., sexual desire). Successful and satisfactory encounters represent an amalgam of subjective assessments that are too far removed from the essential FSD component...
- Evaluating minimal clinically important differences for the acne-specific quality of life questionnaireLori D McLeod
RTI Health Solutions, Research Triangle Institute, North Carolina 27709 2194, USA
Pharmacoeconomics 21:1069-79. 2003..However, the question remained if these statistically significant results were also clinically meaningful...
- The use of the sexual function questionnaire as a screening tool for women with sexual dysfunctionFrances Quirk
Schools of Psychology and Medicine, James Cook University, Townsville, Australia
J Sex Med 2:469-77. 2005..To determine if the validated Sexual Function Questionnaire (SFQ), developed to assess efficacy in female sexual dysfunction (FSD) clinical trials, may also have utility in identifying target populations for such studies...
- Estimating clinically significant differences in quality of life outcomesKathleen W Wyrwich
Saint Louis University, St Louis, MO 63103, USA
Qual Life Res 14:285-95. 2005..The original six articles were presented at the Symposium on Clinical Significance of Quality of Life Measures in Cancer Patients at the Mayo Clinic in April 2002 and subsequently were published in Mayo Clinic Proceedings...
- Assessing clinical significance in measuring oncology patient quality of life: introduction to the symposium, content overview, and definition of termsJeff A Sloan
Department of Health Sciences Research, Mayo Clinic, Rochester, Minn 55905, USA
Mayo Clin Proc 77:367-70. 2002..A secondary goal is to stimulate further discussion and research in the interpretation of QOL assessments...