Hong Ma

Summary

Affiliation: Pennsylvania State University
Country: USA

Publications

  1. pmc Moderate drought causes dramatic floral transcriptomic reprogramming to ensure successful reproductive development in Arabidopsis
    Xuan Ma
    Department of Biology and the Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, State College, PA 16802, USA
    BMC Plant Biol 14:164. 2014
  2. pmc Reevaluation of the evolutionary events within recA/RAD51 phylogeny
    Sree V Chintapalli
    Department of Physiology and Membrane Biology, School of Medicine, University of California Davis, CA, USA
    BMC Genomics 14:240. 2013
  3. pmc A molecular portrait of Arabidopsis meiosis
    Hong Ma
    Department of Biology, The Huck Institutes of the Life Sciences, and the Institute of Molecular Evolutionary Genetics, The Pennsylvania State University, University Park, PA 16802
    Arabidopsis Book 4:e0095. 2006
  4. pmc A physical map for the Amborella trichopoda genome sheds light on the evolution of angiosperm genome structure
    Andrea Zuccolo
    Arizona Genomics Institute, School of Plant Sciences and BIO5 Institute for Collaborative Research, University of Arizona, 1657 East Helen Street, Tucson, AZ 85721, USA
    Genome Biol 12:R48. 2011
  5. pmc Floral gene resources from basal angiosperms for comparative genomics research
    Victor A Albert
    Natural History Museum, University of Oslo, NO 0318 Oslo, Norway
    BMC Plant Biol 5:5. 2005
  6. ncbi request reprint Plant reproduction: GABA gradient, guidance and growth
    Hong Ma
    Department of Biology and the Huck Institute for Life Sciences, The Pennsylvania State University, University Park 16802, USA
    Curr Biol 13:R834-6. 2003
  7. ncbi request reprint Plant G proteins: the different faces of GPA1
    H Ma
    Department of Biology and the Life Sciences Consortium, 504 Wartik Laboratory, Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Curr Biol 11:R869-71. 2001
  8. ncbi request reprint Molecular genetic analyses of microsporogenesis and microgametogenesis in flowering plants
    Hong Ma
    Department of Biology and the Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Annu Rev Plant Biol 56:393-434. 2005
  9. ncbi request reprint Gene regulation: better late than never?
    H Ma
    Department of Biology, 504 Wartik Laboratory, Life Sciences Consortium, Pennsylvania State University, Pennsylvania 16802, USA
    Curr Biol 10:R365-8. 2000
  10. ncbi request reprint Seed development: with or without sex?
    H Ma
    Department of Biology and the Life Sciences Consortium 504 Wartik Laboratory, Pennsylvania State University Pennsylvania, 16802, USA
    Curr Biol 9:R636-9. 1999

Collaborators

Detail Information

Publications99

  1. pmc Moderate drought causes dramatic floral transcriptomic reprogramming to ensure successful reproductive development in Arabidopsis
    Xuan Ma
    Department of Biology and the Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, State College, PA 16802, USA
    BMC Plant Biol 14:164. 2014
    ..This study describes the morphological changes of reproductive development and the comparison of transcriptomes under various drought conditions...
  2. pmc Reevaluation of the evolutionary events within recA/RAD51 phylogeny
    Sree V Chintapalli
    Department of Physiology and Membrane Biology, School of Medicine, University of California Davis, CA, USA
    BMC Genomics 14:240. 2013
    ..To date, efforts to resolve the deep evolutionary origins of this ancient protein family have been hindered by the high sequence divergence between paralogous groups (i.e. ~30% average pairwise identity)...
  3. pmc A molecular portrait of Arabidopsis meiosis
    Hong Ma
    Department of Biology, The Huck Institutes of the Life Sciences, and the Institute of Molecular Evolutionary Genetics, The Pennsylvania State University, University Park, PA 16802
    Arabidopsis Book 4:e0095. 2006
    ..Abbreviations: DAPI, 4',6-diamidino-2-phenylindole; DSB, double strand break; DSBR, double strand break repair; SC, synaptonemal complex; TEM, transmission electron microscopy...
  4. pmc A physical map for the Amborella trichopoda genome sheds light on the evolution of angiosperm genome structure
    Andrea Zuccolo
    Arizona Genomics Institute, School of Plant Sciences and BIO5 Institute for Collaborative Research, University of Arizona, 1657 East Helen Street, Tucson, AZ 85721, USA
    Genome Biol 12:R48. 2011
    ..A physical map, BAC end sequences and sample shotgun sequences provide a first view of the 870 Mbp Amborella genome...
  5. pmc Floral gene resources from basal angiosperms for comparative genomics research
    Victor A Albert
    Natural History Museum, University of Oslo, NO 0318 Oslo, Norway
    BMC Plant Biol 5:5. 2005
    ....
  6. ncbi request reprint Plant reproduction: GABA gradient, guidance and growth
    Hong Ma
    Department of Biology and the Huck Institute for Life Sciences, The Pennsylvania State University, University Park 16802, USA
    Curr Biol 13:R834-6. 2003
    ..A new analysis of an Arabidopsis mutant has provided the strongest evidence yet that a GABA gradient may be a critical signal for correct targeting of the pollen tube...
  7. ncbi request reprint Plant G proteins: the different faces of GPA1
    H Ma
    Department of Biology and the Life Sciences Consortium, 504 Wartik Laboratory, Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Curr Biol 11:R869-71. 2001
    ..Recent studies indicate that the GPA1 protein is involved in a number of very different cellular processes...
  8. ncbi request reprint Molecular genetic analyses of microsporogenesis and microgametogenesis in flowering plants
    Hong Ma
    Department of Biology and the Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Annu Rev Plant Biol 56:393-434. 2005
    ....
  9. ncbi request reprint Gene regulation: better late than never?
    H Ma
    Department of Biology, 504 Wartik Laboratory, Life Sciences Consortium, Pennsylvania State University, Pennsylvania 16802, USA
    Curr Biol 10:R365-8. 2000
    ..The distribution of the genes and nature of their products suggest that this delayed expression of paternal alleles may be a global phenomenon...
  10. ncbi request reprint Seed development: with or without sex?
    H Ma
    Department of Biology and the Life Sciences Consortium 504 Wartik Laboratory, Pennsylvania State University Pennsylvania, 16802, USA
    Curr Biol 9:R636-9. 1999
    ..The products of these genes are similar to Polycomb group proteins, suggesting possible mechanisms for determining whether seeds can be produced sexually or asexually...
  11. ncbi request reprint Functional divergence of the duplicated AtKIN14a and AtKIN14b genes: critical roles in Arabidopsis meiosis and gametophyte development
    Li Quan
    Department of Biology, The Pennsylvania State University, University Park, PA 16802, USA
    Plant J 53:1013-26. 2008
    ....
  12. pmc The evolution of the SEPALLATA subfamily of MADS-box genes: a preangiosperm origin with multiple duplications throughout angiosperm history
    Laura M Zahn
    Department of Biology, Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, 16802, USA
    Genetics 169:2209-23. 2005
    ..Regardless of the mechanism of gene duplication, these pairs of duplicate transcription factors provided new possibilities of genetic interactions that may have been important in the origin of the flower...
  13. pmc The Arabidopsis thaliana PARTING DANCERS gene encoding a novel protein is required for normal meiotic homologous recombination
    Asela J Wijeratne
    Intercollege Graduate Program in Plant Physiology, The Pennsylvania State University, University Park, PA 16802, USA
    Mol Biol Cell 17:1331-43. 2006
    ..Comparison to other genes with limited sequence similarity raises the possibility that PTD may present a previously unknown function conserved in divergent eukaryotic organisms...
  14. ncbi request reprint Regulation of Arabidopsis tapetum development and function by DYSFUNCTIONAL TAPETUM1 (DYT1) encoding a putative bHLH transcription factor
    Wei Zhang
    Department of Biology and the Huck Institutes of Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA
    Development 133:3085-95. 2006
    ..Our results support the hypothesis that DYT1 is a crucial component of a genetic network that controls anther development and function...
  15. pmc Comparative transcriptomics among floral organs of the basal eudicot Eschscholzia californica as reference for floral evolutionary developmental studies
    Laura M Zahn
    Department of Biology, The Pennsylvania State University, University Park, PA 16802, USA
    Genome Biol 11:R101. 2010
    ..However, our understanding of floral developmental processes among the basal eudicots remains limited...
  16. pmc Regulation of flower development in Arabidopsis by SCF complexes
    Weimin Ni
    Department of Biology and the Huck Institutes of Life Sciences, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Plant Physiol 134:1574-85. 2004
    ..These results suggest that SCF complexes regulate several aspects of floral development in Arabidopsis...
  17. doi request reprint Regulation of the Arabidopsis anther transcriptome by DYT1 for pollen development
    Baomin Feng
    Department of Biology, Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802, USA
    Plant J 72:612-24. 2012
    ..Our results demonstrate the important role of DYT1 in regulating anther transcriptome and function, and supporting normal pollen development...
  18. pmc Comparison of next generation sequencing technologies for transcriptome characterization
    P Kerr Wall
    Department of Biology, Institute of Molecular Evolutionary Genetics, and The Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA
    BMC Genomics 10:347. 2009
    ..19). We also generated 454-GS20 sequences and de novo assemblies for the basal eudicot California poppy (Eschscholzia californica) and the magnoliid avocado (Persea americana) using a variety of methods for cDNA synthesis...
  19. pmc Identification of shared single copy nuclear genes in Arabidopsis, Populus, Vitis and Oryza and their phylogenetic utility across various taxonomic levels
    Jill M Duarte
    Department of Biology and the Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA
    BMC Evol Biol 10:61. 2010
    ....
  20. ncbi request reprint EST database for early flower development in California poppy (Eschscholzia californica Cham., Papaveraceae) tags over 6,000 genes from a basal eudicot
    John E Carlson
    The School of Forest Resources and Huck Institutes for Life Sciences, Pennsylvania State University, 323 Forest Resources Building, University Park, 16802, USA
    Plant Mol Biol 62:351-69. 2006
    ....
  21. doi request reprint Phylogenetic analysis of the plant-specific zinc finger-homeobox and mini zinc finger gene families
    Wei Hu
    Department of Biology and the Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802, USA
    J Integr Plant Biol 50:1031-45. 2008
    ..Finally, genome duplication might have contributed substantially to the expansion of family size in angiosperms and caused a high level of functional redundancy/overlap in these genes...
  22. doi request reprint Ectopic expression of the Arabidopsis MINI ZINC FINGER1 and MIF3 genes induces shoot meristems on leaf margins
    Wei Hu
    Department of Biology, Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802, USA
    Plant Mol Biol 76:57-68. 2011
    ....
  23. ncbi request reprint Genome-wide expression profiling and identification of gene activities during early flower development in Arabidopsis
    Xiaohong Zhang
    Department of Biology and the Huck Institutes of the Life Sciences, The Pennsylvania State University, 405D Life Sciences Building, University Park, PA 16802, USA
    Plant Mol Biol 58:401-19. 2005
    ..RT-PCR results of selected genes are consistent with the results from these microarrays and suggest that the relative signal intensities detected with the Affymetrix microarray are reliable estimates of gene expression...
  24. pmc Members of the Arabidopsis-SKP1-like gene family exhibit a variety of expression patterns and may play diverse roles in Arabidopsis
    Dazhong Zhao
    Department of Biology and Huck Institute for Life Sciences, 313 Wartik Laboratory, The Pennsylvania State University, University Park, PA 16802, USA
    Plant Physiol 133:203-17. 2003
    ..The diverse expression patterns and distinct defects observed in RNAi plants suggest that the ASK gene family may collectively perform a range of functions and may regulate different developmental and physiological processes...
  25. ncbi request reprint Conservation and divergence in the AGAMOUS subfamily of MADS-box genes: evidence of independent sub- and neofunctionalization events
    Laura M Zahn
    Department of Biology, The Huck Institutes of the Life Sciences, and the Institute for Molecular Genetics and Evolution, The Pennsylvania State University, University Park, PA 16802, USA
    Evol Dev 8:30-45. 2006
    ....
  26. ncbi request reprint Conservation and divergence of ASK1 and ASK2 gene functions during male meiosis in Arabidopsis thaliana
    Dazhong Zhao
    Department of Biology, Huck Institute for Life Sciences, 315 Wartik Laboratory, Pennsylvania State University, University Park, PA 16802, USA
    Plant Mol Biol 53:163-73. 2003
    ..Our results suggest that ASK2 partially substitutes for ASK1 if expressed at higher than normal levels...
  27. pmc Genome-wide analysis of the cyclin family in Arabidopsis and comparative phylogenetic analysis of plant cyclin-like proteins
    Guanfang Wang
    Department of Biology and the Huck Institutes of Life Sciences, Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Plant Physiol 135:1084-99. 2004
    ..Our study provides an opportunity to rapidly assess the position of plant cyclin genes in terms of evolution and classification, serving as a guide for further functional study of plant cyclins...
  28. pmc Widespread genome duplications throughout the history of flowering plants
    Liying Cui
    Department of Biology, The Pennsylvania State University, University Park 16802, USA
    Genome Res 16:738-49. 2006
    ..We hypothesize that evidence of an ancient duplication observed in the Nuphar data may represent a genome duplication in the common ancestor of all or most extant angiosperms, except Amborella...
  29. pmc The BAM1/BAM2 receptor-like kinases are important regulators of Arabidopsis early anther development
    Carey L H Hord
    Department of Biology and the Huck Institutes for the Life Sciences, Pensylvania State University, University Park, Pensylvania 16802, USA
    Plant Cell 18:1667-80. 2006
    ..This finding may have implications for the evolution of multiple signaling pathways in specifying cell types for microsporogenesis...
  30. doi request reprint Regulation of Arabidopsis early anther development by the mitogen-activated protein kinases, MPK3 and MPK6, and the ERECTA and related receptor-like kinases
    Carey L H Hord
    Department of Biology, Pennsylvania State University, University Park, PA 16802, USA
    Mol Plant 1:645-58. 2008
    ....
  31. ncbi request reprint Differential gene expression in Arabidopsis wild-type and mutant anthers: insights into anther cell differentiation and regulatory networks
    Asela J Wijeratne
    Intercollege Graduate Program in Plant Biology, Pennsylvania State University, University Park, PA 16802, USA
    Plant J 52:14-29. 2007
    ..This model includes hypotheses that can be tested experimentally to gain further understanding of the mechanisms controlling anther development...
  32. ncbi request reprint Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis
    Jill M Duarte
    Department of Biology, Institute of Molecular Evolutionary Genetics, and Huck Institutes of the Life Sciences, The Pennsylvania State University, USA
    Mol Biol Evol 23:469-78. 2006
    ....
  33. pmc Characterization of meiotic crossovers and gene conversion by whole-genome sequencing in Saccharomyces cerevisiae
    Ji Qi
    Center for Comparative Genomics and Bioinformatics, Pennsylvania State University, University Park, PA 16802, USA
    BMC Genomics 10:475. 2009
    ..Differences at the nucleotide level associated with COs and NCOs enable us to detect these recombination events and their distributions...
  34. pmc The Arabidopsis AtRAD51 gene is dispensable for vegetative development but required for meiosis
    Wuxing Li
    Department of Biology and the Huck Institutes of Life Sciences, Pennsylvania State University, University Park, PA 16802, USA
    Proc Natl Acad Sci U S A 101:10596-601. 2004
    ..Furthermore, major aspects of meiotic recombination seem to be conserved between yeast and plants, especially the fact that chromosome pairing and synapsis depend on the function of SPO11 and RAD51...
  35. doi request reprint Ancestral polyploidy in seed plants and angiosperms
    Yuannian Jiao
    Intercollege Graduate Degree Program in Plant Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Nature 473:97-100. 2011
    ....
  36. ncbi request reprint ASK1, a SKP1 homolog, is required for nuclear reorganization, presynaptic homolog juxtaposition and the proper distribution of cohesin during meiosis in Arabidopsis
    Dazhong Zhao
    Department of Biology and the Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA
    Plant Mol Biol 62:99-110. 2006
    ....
  37. pmc Type I MADS-box genes have experienced faster birth-and-death evolution than type II MADS-box genes in angiosperms
    Jongmin Nam
    Institute of Molecular Evolutionary Genetics and Department of Biology, Pennsylvania State University, University Park, PA 16802, USA
    Proc Natl Acad Sci U S A 101:1910-5. 2004
    ..Furthermore, the higher rate of birth-and-death evolution in type I genes appeared partly due to a higher frequency of segmental gene duplication and weaker purifying selection in type I than in type II genes...
  38. pmc The origins and early evolution of DNA mismatch repair genes--multiple horizontal gene transfers and co-evolution
    Zhenguo Lin
    Department of Biology and Institute of Molecular Evolutionary Genetics, Pennsylvania State University, University Park, PA 16802, USA
    Nucleic Acids Res 35:7591-603. 2007
    ..Our work presents an overall portrait of the evolution of these important genes in DNA metabolism and also provides further understanding about the early evolution of cellular organisms...
  39. pmc Ultraconserved coding regions outside the homeobox of mammalian Hox genes
    Zhenguo Lin
    Department of Biology and Institute of Molecular Evolutionary Genetics, Pennsylvania State University, University Park, PA 16802, USA
    BMC Evol Biol 8:260. 2008
    ..In this study, we used comparative genomic methods to infer possible functional elements in the coding regions of mammalian Hox genes...
  40. pmc Homolog interaction during meiotic prophase I in Arabidopsis requires the SOLO DANCERS gene encoding a novel cyclin-like protein
    Yoshitaka Azumi
    Department of Biology, Life Sciences Consortium, The Pennsylvania State University, University Park, PA 16802, USA
    EMBO J 21:3081-95. 2002
    ..These results argue strongly that homolog interactions during meiotic prophase I require a novel meiosis-specific cyclin in Arabidopsis...
  41. ncbi request reprint Double-stranded DNA breaks and gene functions in recombination and meiosis
    Wuxing Li
    The Department of Biology, The Intercollege Graduate Degree Program in Plant Physiology, The Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA
    Cell Res 16:402-12. 2006
    ..Recent discoveries on the functions of these RecA homologs have improved the understanding of the mechanisms underlying meiotic homologous recombination...
  42. ncbi request reprint The Arabidopsis ROCK-N-ROLLERS gene encodes a homolog of the yeast ATP-dependent DNA helicase MER3 and is required for normal meiotic crossover formation
    Changbin Chen
    Department of Biology and the Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA
    Plant J 43:321-34. 2005
    ....
  43. pmc The excess microsporocytes1 gene encodes a putative leucine-rich repeat receptor protein kinase that controls somatic and reproductive cell fates in the Arabidopsis anther
    Da Zhong Zhao
    Department of Biology and the Life Sciences Consortium, Pennsylvania State University, Pennsylvania 16802, USA
    Genes Dev 16:2021-31. 2002
    ....
  44. doi request reprint Arabidopsis PTD is required for type I crossover formation and affects recombination frequency in two different chromosomal regions
    Pingli Lu
    Institute of Plant Biology, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai 200433, China Department of Biology and the Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802, USA Electronic address
    J Genet Genomics 41:165-75. 2014
    ..63% and 22.26% in wild-type to 1.14% and 6.36%, respectively, in the ptd-2 mutant. These results revealed new aspects of PTD function in meiotic crossover formation. ..
  45. pmc Analysis of Arabidopsis genome-wide variations before and after meiosis and meiotic recombination by resequencing Landsberg erecta and all four products of a single meiosis
    Pingli Lu
    Department of Biology and the Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA
    Genome Res 22:508-18. 2012
    ..In particular, meiosis provides a rapid mechanism to generate copy-number variation (CNV) of sequences that have different chromosomal positions in Col and Ler...
  46. ncbi request reprint Isolation, sequence analysis, and expression studies of florally expressed cDNAs in Arabidopsis
    Wei Hu
    Department of Biology, and the Huck Institute of Life Sciences, Pennsylvania State University, University Park, PA 16802, USA
    Plant Mol Biol 53:545-63. 2003
    ..We suggest that the genes encoding putative regulatory proteins and at least some proteins with currently unknown functions might play important roles during flowering...
  47. pmc Evolutionary history of histone demethylase families: distinct evolutionary patterns suggest functional divergence
    Xiaofan Zhou
    The Intercollege Graduate Program in Cell and Developmental Biology, Huck Institutes of Life Sciences, Pennsylvania State University, 415 Life Science Building, University Park, Pennsylvania 16802, USA
    BMC Evol Biol 8:294. 2008
    ..Although more and more KDM1 and JmjC proteins have been shown to have histone demethylase activity, our knowledge about their evolution history is limited...
  48. ncbi request reprint Characterization of a novel putative zinc finger gene MIF1: involvement in multiple hormonal regulation of Arabidopsis development
    Wei Hu
    Department of Biology, and The Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802, USA
    Plant J 45:399-422. 2006
    ..We propose that MIF1, or the protein(s) with which MIF1 interacts, is involved in mediating the control of plant development by multiple hormones...
  49. doi request reprint Analysis of the Arabidopsis floral proteome: detection of over 2 000 proteins and evidence for posttranslational modifications
    Baomin Feng
    Department of Biology, The Pennsylvania State University, University Park, PA 16802, USA
    J Integr Plant Biol 51:207-23. 2009
    ..Our results allow the formulation of hypotheses regarding post-translational regulation of proteins in the flower, providing new understanding about Arabidopsis flower development and physiology...
  50. pmc Origins and evolution of the recA/RAD51 gene family: evidence for ancient gene duplication and endosymbiotic gene transfer
    Zhenguo Lin
    Department of Biology and the Institute of Molecular Evolutionary Genetics, Pennsylvania State University, University Park, PA 16802, USA
    Proc Natl Acad Sci U S A 103:10328-33. 2006
    ..These results suggest that endosymbiotic transfer of recA genes occurred from mitochondria and chloroplasts to nuclear genomes of ancestral eukaryotes...
  51. pmc The AtRAD51C gene is required for normal meiotic chromosome synapsis and double-stranded break repair in Arabidopsis
    Wuxing Li
    Department of Biology and the Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Plant Physiol 138:965-76. 2005
    ..These results demonstrate that AtRAD51C is essential for normal meiosis and is probably required for homologous synapsis...
  52. pmc Characterization of the basal angiosperm Aristolochia fimbriata: a potential experimental system for genetic studies
    Barbara J Bliss
    Department of Biology, Institute of Molecular Evolutionary Genetics, and The Huck Institutes of the Life Sciences, 201 Life Sciences Building, Pennsylvania State University, University Park, PA 16802, USA
    BMC Plant Biol 13:13. 2013
    ..It would be desirable to identify a basal angiosperm experimental system that possesses many of the features found in existing plant model systems (e.g., Arabidopsis and Oryza)...
  53. pmc AMS-dependent and independent regulation of anther transcriptome and comparison with those affected by other Arabidopsis anther genes
    Xuan Ma
    Department of Biology and the Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA
    BMC Plant Biol 12:23. 2012
    ..Despite the increasing knowledge of genes that contribute to anther development, the regulatory mechanisms controlling this process are still unclear...
  54. pmc Phylogenetic detection of numerous gene duplications shared by animals, fungi and plants
    Xiaofan Zhou
    Department of Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Genome Biol 11:R38. 2010
    ..Although gene duplications in each lineage have been studied extensively in various contexts, the extent of gene duplication prior to the split of plants and animals/fungi is not clear...
  55. pmc Comparative analysis of neural transcriptomes and functional implication of unannotated intronic expression
    Yazhou Sun
    Department of Biology, Pennsylvania State University, University Park, PA 16802, USA
    BMC Genomics 12:494. 2011
    ....
  56. pmc A minus-end-directed kinesin with plus-end tracking protein activity is involved in spindle morphogenesis
    J Christian Ambrose
    Department of Biology, The Pennsylvania State University, University Park, 16802, USA
    Mol Biol Cell 16:1584-92. 2005
    ..Based on these data, we propose a model in which ATK5 uses plus-end tracking to reach spindle midzones, where it then organizes microtubules via minus-end-directed motor activity...
  57. ncbi request reprint The ASK1 gene regulates B function gene expression in cooperation with UFO and LEAFY in Arabidopsis
    D Zhao
    Department of Biology and the Life Sciences Consortium, 504 Wartik Laboratory, Pennsylvania State University, University Park, PA 16802, USA
    Development 128:2735-46. 2001
    ..Our genetic studies also indicate that ASK1 and UFO play a role in regulating the number of floral organ primordia, and we discuss possible mechanisms for such a regulation...
  58. pmc Stable and dynamic nucleosome states during a meiotic developmental process
    Liye Zhang
    Center for Eukaryotic Gene Regulation, Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Genome Res 21:875-84. 2011
    ..Our findings suggest that, during meiosis, the basic features of genomic chromatin organization are essentially a fixed property of chromosomes, but tweaked in a restricted and program-specific manner...
  59. ncbi request reprint Flowering time: from photoperiodism to florigen
    H Ma
    Department of Biology, Pennsylvania State University, Wartik Laboratory, University Park 16802 5301, USA
    Curr Biol 8:R690-2. 1998
    ....
  60. pmc A kinesin mutant with an atypical bipolar spindle undergoes normal mitosis
    A I Marcus
    The Pennsylvania State University, Department of Biology, 208 Mueller Laboratory, University Park, Pennsylvania 16801, USA
    Mol Biol Cell 14:1717-26. 2003
    ..Moreover, ATK1 function seems to be dosage-dependent, because cells containing one wild-type allele take significantly longer to proceed to anaphase as compared with cells containing two wild-type alleles...
  61. ncbi request reprint Antiquity and evolution of the MADS-box gene family controlling flower development in plants
    Jongmin Nam
    Institute of Molecular Evolutionary Genetics and Department of Biology, Pennsylvania State University, USA
    Mol Biol Evol 20:1435-47. 2003
    ..Our study supports the idea that there are two main evolutionary lineages (type I and type II) of MADS-box genes in plants and animals...
  62. pmc Transcriptome of embryonic and neonatal mouse cortex by high-throughput RNA sequencing
    Xinwei Han
    Department of Biology, Pennsylvania State University, University Park, PA 16802, USA
    Proc Natl Acad Sci U S A 106:12741-6. 2009
    ..Our transcriptome analysis may serve as a blueprint for gene expression pattern and provide functional clues of previously unknown genes and disease-related genes during early brain development...
  63. ncbi request reprint To B or Not to B a flower: the role of DEFICIENS and GLOBOSA orthologs in the evolution of the angiosperms
    L M Zahn
    Department of Biology, Institute of Molecular Evolutionary Genetics, Pennsylvania State University, University Park, PA 16802, USA
    J Hered 96:225-40. 2005
    ..Our analyses demonstrate that although the primary role of the DEF/GLO subfamily appears to be in specifying the stamens and inner perianth, several examples of potential sub- and neofunctionalization are observed...
  64. pmc Plant Signaling 2000. Cross talk among geneticists, physiologists, and ecologists
    D J Cosgrove
    Department of Biology, Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Plant Physiol 124:499-506. 2000
    ....
  65. pmc Flower development under drought stress: morphological and transcriptomic analyses reveal acute responses and long-term acclimation in Arabidopsis
    Zhao Su
    Department of Biology and the Huck Institutes of the Life Sciences, Pensylvania State University, University Park, Pensylvania 16802
    Plant Cell 25:3785-807. 2013
    ..Our study reveals a regulatory cascade in reproductive responses and acclimation under drought...
  66. ncbi request reprint The Arabidopsis ATK1 gene is required for spindle morphogenesis in male meiosis
    Changbin Chen
    Department of Biology, The Pennsylvania State University, University Park, PA 16802 USA
    Development 129:2401-9. 2002
    ..Therefore, the ATK1 gene plays a crucial role in spindle morphogenesis in male Arabidopsis meiosis...
  67. pmc The Arabidopsis SKP1-LIKE1 gene is essential for male meiosis and may control homologue separation
    M Yang
    Department of Biology, Pennsylvania State University, University Park, PA 16802, USA
    Proc Natl Acad Sci U S A 96:11416-21. 1999
    ....
  68. pmc Identification of an SCF ubiquitin-ligase complex required for auxin response in Arabidopsis thaliana
    W M Gray
    Department of Biology, Indiana University, Bloomington, Indiana 47405, USA
    Genes Dev 13:1678-91. 1999
    ..Further, overexpression of TIR1 promotes auxin response suggesting that SCFTIR1 is limiting for the response. These results provide new support for a model in which auxin action depends on the regulated proteolysis of repressor proteins...
  69. pmc Proteomics and transcriptomics analyses of Arabidopsis floral buds uncover important functions of ARABIDOPSIS SKP1-LIKE1
    Dihong Lu
    Intercollege Graduate Degree Program in Plant Biology, The Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA, 16802, USA
    BMC Plant Biol 16:61. 2016
    ..However, the molecular impact of ASK1-containing SCF E3 ubiquitin ligases (ASK1-E3s) on the floral proteome and transcriptome is unknown...
  70. pmc Male meiotic spindle lengths in normal and mutant arabidopsis cells
    M Yang
    Department of Biology and the Life Sciences Consortium, Pennsylvania State University, 519 Wartik Lab, University Park, Pennsylvania 16802, USA
    Plant Physiol 126:622-30. 2001
    ..7 microm. These findings strongly suggest that the spindle elongates in response to status of chromosome separation, and perhaps there are conserved mechanisms controlling the extent of spindle elongation...
  71. pmc Cohesin interaction with centromeric minichromosomes shows a multi-complex rod-shaped structure
    Alexandra Surcel
    The Intercollege Graduate Program in Cell and Developmental Biology, The Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, Pennsylvania, United States of America
    PLoS ONE 3:e2453. 2008
    ..These molecules seem to be packed into a single thick rod, suggesting that the Smc1p and Smc3p subunits may interact extensively...
  72. ncbi request reprint Gametophyte development
    Wuxing Li
    Department of Biology and the Life Sciences Consortium, the Intercollege Graduate Program in Plant Physiology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Curr Biol 12:R718-21. 2002
  73. pmc Isolation and characterization of kinase interacting protein 1, a pollen protein that interacts with the kinase domain of PRK1, a receptor-like kinase of petunia
    A L Skirpan
    Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Plant Physiol 126:1480-92. 2001
    ..In situ hybridization showed that PRK1 and KIP1 transcripts were localized in the cytoplasm of pollen. PRK1-K phosphorylated KIP1-NT (amino acids 1--716), whereas PRK1-K462R only weakly phosphorylated KIP1-NT in vitro...
  74. ncbi request reprint Highly heterogeneous rates of evolution in the SKP1 gene family in plants and animals: functional and evolutionary implications
    Hongzhi Kong
    Laboratory of Systematic and Evolutionary Botany, Institute of Botany, The Chinese Academy of Sciences, Beijing, China
    Mol Biol Evol 21:117-28. 2004
    ....
  75. ncbi request reprint Proteomic identification of potential target proteins regulated by an ASK1-mediated proteolysis pathway
    Xiaofeng Wang
    1State Key Laboratory of Genetic Engineering, Department of Biochemistry and Molecular Biology, School of Life Sciences, Fudan University, Shanghai, 200433, China
    Cell Res 16:489-98. 2006
    ..These results help to elucidate the pleiotropic functions of ASK1 in Arabidopsis developmental processes and also demonstrate the importance and necessity of studying protein levels with respect to gene functions...
  76. ncbi request reprint Plant fertility defects induced by the enhanced expression of microRNA167
    Peng Ru
    National Laboratory of Plant Molecular Genetics, Shanghai Institute of Plant Physiology and Ecology, Shanghai Institute for Biological Sciences, 300 Fenglin Road, Shanghai 200032, China
    Cell Res 16:457-65. 2006
    ..Our results provide an important link between the miRNA-mediated regulatory pathway of gene expression and the auxin signaling network promoting plant reproductive development...
  77. pmc Arabidopsis MALE STERILITY1 encodes a PHD-type transcription factor and regulates pollen and tapetum development
    Takuya Ito
    Antibiotics Laboratory, RIKEN, Tsukuba 305 0074, Japan
    Plant Cell 19:3549-62. 2007
    ..From these results, we discuss a role of MS1 in pollen and tapetum development and the conservation of MS1 function in flowering plants...
  78. pmc The Arabidopsis MALE MEIOCYTE DEATH1 gene encodes a PHD-finger protein that is required for male meiosis
    Xiaohui Yang
    Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio 45056, USA
    Plant Cell 15:1281-95. 2003
    ..MMD1 is expressed preferentially during male meiosis. Our results suggest that MMD1 may be involved in the regulation of gene expression during meiosis and that the mmd1 mutation triggers cell death in male meiocytes...
  79. ncbi request reprint Towards a comprehensive integration of morphological and genetic studies of floral development
    Matyas Buzgo
    Department of Botany and the Florida Museum of Natural History, University of Florida, Gainesville, FL 32611 8526, USA
    Trends Plant Sci 9:164-73. 2004
    ..Taxa occupying key phylogenetic positions offer great potential for generating hypotheses about the regulation of floral development...
  80. ncbi request reprint Expression of floral MADS-box genes in basal angiosperms: implications for the evolution of floral regulators
    Sangtae Kim
    Department of Botany, University of Florida, Gainesville, FL 32611, USA
    Plant J 43:724-44. 2005
    ....
  81. ncbi request reprint The GAOLAOZHUANGREN1 gene encodes a putative glycosyltransferase that is critical for normal development and carbohydrate metabolism
    Minghai Shao
    National Laboratory of Molecular Genetics, Shanghai Institute of Plant Physiology and Ecology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, 300 Fenglin Road, Shanghai 200032, China
    Plant Cell Physiol 45:1453-60. 2004
    ..These, together with the GLZ1 expression pattern, suggest a requirement for the GLZ1 function in normal sink-source transition during plant development...
  82. pmc Genome-wide analysis of basic/helix-loop-helix transcription factor family in rice and Arabidopsis
    Xiaoxing Li
    Shanghai Jiao Tong University Shanghai Institutes for Biological Sciences Pennsylvania State University Joint Center for Life Sciences, Shanghai Jiao Tong University, Shanghai, People s Republic of China, 200240
    Plant Physiol 141:1167-84. 2006
    ..In addition, similar expression patterns suggest functional conservation between some rice bHLH genes and their close Arabidopsis homologs...
  83. ncbi request reprint Missing links: the genetic architecture of flowers [correction of flower] and floral diversification
    Douglas E Soltis
    Dept Botany and Genetics Institute, University of Florida, Gainesville, FL 32611, USA
    Trends Plant Sci 7:22-31; dicussion 31-4. 2002
    ....
  84. ncbi request reprint GC-GAP, a Rho family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2
    Chunmei Zhao
    Burnham Institute, La Jolla, California 92037, USA
    J Biol Chem 278:34641-53. 2003
    ....
  85. pmc Arabidopsis genes AS1, AS2, and JAG negatively regulate boundary-specifying genes to promote sepal and petal development
    Ben Xu
    National Laboratory of Plant Molecular Genetics, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 200032, China
    Plant Physiol 146:566-75. 2008
    ..Together, our data reveal a previously unrecognized fundamental regulation by which AS1, AS2, and JAG act to define sepal and petal from their boundaries...
  86. ncbi request reprint The floral genome: an evolutionary history of gene duplication and shifting patterns of gene expression
    Douglas E Soltis
    Department of Botany and the Genetics Institute, University of Florida, Gainesville, FL 32611, USA
    Trends Plant Sci 12:358-67. 2007
    ..g. Amborella) result from a gradient in the level of expression of floral organ identity genes across the developing floral meristem...
  87. ncbi request reprint Patterns of gene duplication in the plant SKP1 gene family in angiosperms: evidence for multiple mechanisms of rapid gene birth
    Hongzhi Kong
    State Key Laboratory of Systematic and Evolutionary Botany, Institute of Botany, The Chinese Academy of Sciences, Beijing 100093, China
    Plant J 50:873-85. 2007
    ..Our study represents a thorough investigation showing that retroposition can play an important role in the evolution of a plant gene family whose members do not encode mobile elements...
  88. pmc The rice tapetum degeneration retardation gene is required for tapetum degradation and anther development
    Na Li
    Shanghai Jiao Tong University Shanghai Institutes for Biological Sciences Pensylvania State University Joint Center for Life Sciences, Shanghai 200240, China
    Plant Cell 18:2999-3014. 2006
    ..These results indicate that TDR is a key component of the molecular network regulating rice tapetum development and degeneration...
  89. pmc The floral organ number4 gene encoding a putative ortholog of Arabidopsis CLAVATA3 regulates apical meristem size in rice
    Huangwei Chu
    Shanghai Jiaotong University, Shanghai Institutes for Biological Sciences, Shanghai, China
    Plant Physiol 142:1039-52. 2006
    ..However, exogenous FON4p did not have an obvious effect on limiting both rice and Arabidopsis root meristems, suggesting that the CLE motifs of Arabidopsis CLV3 and FON4 are potentially functionally divergent...
  90. ncbi request reprint The Arabidopsis SKP1 homolog ASK1 controls meiotic chromosome remodeling and release of chromatin from the nuclear membrane and nucleolus
    Xiaohui Yang
    Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056, USA
    J Cell Sci 119:3754-63. 2006
    ..These results raise the interesting possibility that ASK1 controls chromatin structure by targeting of either an early regulator of meiotic progression or possibly matrix attachment proteins for destruction...
  91. ncbi request reprint The effects of epidermal growth factor on gene expression in human fibroblasts
    Hong Ma
    Department of Biochemistry and Molecular Biology, Health Science Center, Peking University, Beijing, People s Republic of China
    In Vitro Cell Dev Biol Anim 38:481-6. 2002
    ....
  92. ncbi request reprint Peroxisome proliferator-activated receptor delta expression and regulation in mouse uterus during embryo implantation and decidualization
    Nai Zheng Ding
    College of Life Sciences, Northeast Agricultural University, Harbin, China
    Mol Reprod Dev 66:218-24. 2003
    ..These data suggest that PPARdelta expression at implantation sites require the presence of an active blastocyst and may play an essential role for blastocyst implantation...
  93. ncbi request reprint Engineering the response to vascular injury: divergent effects of deregulated E2F1 expression on vascular smooth muscle cells and endothelial cells result in endothelial recovery and inhibition of neointimal growth
    David A Goukassian
    Department of Medicine, Division of Cardiovascular Research, St Elizabeth s Medical Center, Boston, Mass, USA
    Circ Res 93:162-9. 2003
    ....
  94. ncbi request reprint mRNA level of alpha-2-macroglobulin as an aging biomarker of human fibroblasts in culture
    Hong Ma
    Department of Biochemistry and Molecular Biology, Peking University Health Science Center, 38 Xueyuan Road, Beijing 100083, China
    Exp Gerontol 39:415-21. 2004
    ..mRNA level of alpha(2)M showed significant difference between newborn and old human leucocytes, which suggest that the mRNA level of alpha(2)M may be used as a biomarker of aging in vivo...
  95. ncbi request reprint Genetics of meiotic prophase I in plants
    Olivier Hamant
    Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA
    Annu Rev Plant Biol 57:267-302. 2006
    ..Based on these recent data, essentially from maize and Arabidopsis, we discuss the conserved and plant-specific aspects of meiosis commitment and meiotic prophase I features...
  96. ncbi request reprint Resources for targeted insertional and deletional mutagenesis in Arabidopsis
    Sen Zhang
    National Laboratory of Plant Molecular Genetics, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, 300 Fenglin Road, Shanghai 200032, China
    Plant Mol Biol 53:133-50. 2003
    ..To facilitate the use of this targeted mutagenesis system. we have constructed a searchable database of the mapped Ds T-DNA integration sites...
  97. pmc The SCF(COI1) ubiquitin-ligase complexes are required for jasmonate response in Arabidopsis
    Linghui Xu
    Institute of Biotechnology Research, Chinese Academy of Agricultural Sciences, Beijing 100081, China
    Plant Cell 14:1919-35. 2002
    ..These results suggest that the COI1-mediated JA response is dependent on the SCF(COI1) complexes in Arabidopsis and that the AXR1-dependent modification of the AtCUL1 subunit of SCF(COI1) complexes is important for JA signaling...
  98. pmc The ASK1 and ASK2 genes are essential for Arabidopsis early development
    Fuquan Liu
    Laboratory of Plant Signal Transduction, Institute of Molecular and Cell Biology, 117609 Republic of Singapore
    Plant Cell 16:5-20. 2004
    ..We propose that mutations in ASK1 and ASK2 abolish all of the ASK1- and ASK2-based SCF and non-SCF complexes, resulting in alteration of gene expression and leading to defects in growth and development...
  99. ncbi request reprint Characterization of an unusual Ds transposable element in Arabidopsis thaliana: insertion of an abortive circular transposition intermediate
    Xiaohui Yang
    The Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056, USA
    Plant Mol Biol 55:905-17. 2004
    ..In addition, a revertant analysis on mmd1 plants demonstrated that Ds-mmd1 can be eliminated from the genome in an Ac -dependent process...

Research Grants2

  1. Control of Meiotic Homolog Segregation in Arabidopsis
    Hong Ma; Fiscal Year: 2004
    ..Furthermore, molecular and cell biological experiments will be done to characterize the expression pattern and protein localization of SDS, and to isolate a putative SDS-like gene. ..
  2. RAD51 gene functions in mitosis and meiosis of zebrafish
    Hong Ma; Fiscal Year: 2004
    ..We will test this hypothesis using morpholino knockdowns of these genes. These experiments will pave the way for more extensive studies in the near future. ..