Mitchell M Holland

Summary

Affiliation: Pennsylvania State University
Country: USA

Publications

  1. doi request reprint MPS analysis of the mtDNA hypervariable regions on the MiSeq with improved enrichment
    Mitchell M Holland
    Forensic Science Program, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, 339 Whitmore Laboratory, University Park, PA, 16802, USA
    Int J Legal Med . 2017
  2. doi request reprint Evaluation of the RapidHIT™ 200, an automated human identification system for STR analysis of single source samples
    Mitchell Holland
    Forensic Science Program, The Pennsylvania State University, 107 Whitmore Laboratory, University Park, PA 16802, USA Electronic address
    Forensic Sci Int Genet 14:76-85. 2015
  3. doi request reprint GeneMarker® HID: A reliable software tool for the analysis of forensic STR data
    Mitchell M Holland
    The Pennsylvania State University, 107 Whitmore Laboratory, University Park, PA 16802, USA
    J Forensic Sci 56:29-35. 2011
  4. pmc Second generation sequencing allows for mtDNA mixture deconvolution and high resolution detection of heteroplasmy
    Mitchell M Holland
    Forensic Science Program, The Pennsylvania State University, University Park, PA 16870, USA
    Croat Med J 52:299-313. 2011
  5. doi request reprint Considering DNA damage when interpreting mtDNA heteroplasmy in deep sequencing data
    Molly M Rathbun
    Forensic Science Program, Biochemistry and Molecular Biology Department, The Pennsylvania State University, 014 Thomas Building, University Park, PA 16802, United States
    Forensic Sci Int Genet 26:1-11. 2017
  6. pmc Development and assessment of an optimized next-generation DNA sequencing approach for the mtgenome using the Illumina MiSeq
    Jennifer A McElhoe
    Forensic Science Program, The Pennsylvania State University, University Park, PA 16802, USA Electronic address
    Forensic Sci Int Genet 13:20-9. 2014
  7. doi request reprint Molecular analysis of the human mitochondrial DNA control region for forensic identity testing
    Mitchell M Holland
    Pennsylvania State University, University Park, Pennsylvania, USA
    Curr Protoc Hum Genet . 2012

Collaborators

  • Walther Parson
  • Jennifer A McElhoe
  • Molly M Rathbun
  • Kateryna D Makova
  • Ian M Paul
  • Christine H Baker
  • Marcia Shu Wei Su
  • Seth A Faith
  • Brian Young

Detail Information

Publications7

  1. doi request reprint MPS analysis of the mtDNA hypervariable regions on the MiSeq with improved enrichment
    Mitchell M Holland
    Forensic Science Program, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, 339 Whitmore Laboratory, University Park, PA, 16802, USA
    Int J Legal Med . 2017
    ..Given that Ex Taq® HS is a proofreading enzyme, using this approach should allow for improved analysis of low-level mtDNA heteroplasmy...
  2. doi request reprint Evaluation of the RapidHIT™ 200, an automated human identification system for STR analysis of single source samples
    Mitchell Holland
    Forensic Science Program, The Pennsylvania State University, 107 Whitmore Laboratory, University Park, PA 16802, USA Electronic address
    Forensic Sci Int Genet 14:76-85. 2015
    ....
  3. doi request reprint GeneMarker® HID: A reliable software tool for the analysis of forensic STR data
    Mitchell M Holland
    The Pennsylvania State University, 107 Whitmore Laboratory, University Park, PA 16802, USA
    J Forensic Sci 56:29-35. 2011
    ..The results suggest that laboratories can reduce the time required for data analysis by at least 25% when using GeneMarker HID...
  4. pmc Second generation sequencing allows for mtDNA mixture deconvolution and high resolution detection of heteroplasmy
    Mitchell M Holland
    Forensic Science Program, The Pennsylvania State University, University Park, PA 16870, USA
    Croat Med J 52:299-313. 2011
    ..To use parallel array pyrosequencing to deconvolute mixtures of mitochondrial DNA (mtDNA) sequence and provide high resolution analysis of mtDNA heteroplasmy...
  5. doi request reprint Considering DNA damage when interpreting mtDNA heteroplasmy in deep sequencing data
    Molly M Rathbun
    Forensic Science Program, Biochemistry and Molecular Biology Department, The Pennsylvania State University, 014 Thomas Building, University Park, PA 16802, United States
    Forensic Sci Int Genet 26:1-11. 2017
    ..These findings are particularly relevant to clinical and forensic investigations...
  6. pmc Development and assessment of an optimized next-generation DNA sequencing approach for the mtgenome using the Illumina MiSeq
    Jennifer A McElhoe
    Forensic Science Program, The Pennsylvania State University, University Park, PA 16802, USA Electronic address
    Forensic Sci Int Genet 13:20-9. 2014
    ....
  7. doi request reprint Molecular analysis of the human mitochondrial DNA control region for forensic identity testing
    Mitchell M Holland
    Pennsylvania State University, University Park, Pennsylvania, USA
    Curr Protoc Hum Genet . 2012
    ..The focus is on applications to forensic casework, and a number of case examples are provided. Any laboratory working with DNA from old or "ancient" samples will benefit from this information...