Timothy W Rhoads

Summary

Affiliation: Oregon State University
Country: USA

Publications

  1. pmc Measuring copper and zinc superoxide dismutase from spinal cord tissue using electrospray mass spectrometry
    Timothy W Rhoads
    Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331, USA
    Anal Biochem 415:52-8. 2011
  2. pmc Using theoretical protein isotopic distributions to parse small-mass-difference post-translational modifications via mass spectrometry
    Timothy W Rhoads
    Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331, USA
    J Am Soc Mass Spectrom 24:115-24. 2013
  3. pmc Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SOD(G93A) mice co-expressing the Copper-Chaperone-for-SOD
    Jared R Williams
    Linus Pauling Institute, Department of Biochemistry and Biophysics, Oregon State University, United States
    Neurobiol Dis 89:1-9. 2016

Collaborators

  • Peter J Crouch
  • Blaine R Roberts
  • Jared R Williams
  • Nathan I Lopez
  • Cliff Pereira
  • Jeffrey L Elliott
  • Pamela R Beilby
  • Maria Clara Franco
  • Marjatta Son
  • Luis Barbeito
  • Joseph S Beckman
  • Erin J McAllum
  • Edwin M Labut
  • ALVARO G ESTEVEZ
  • Emiliano Trias
  • C Samuel Bradford

Detail Information

Publications3

  1. pmc Measuring copper and zinc superoxide dismutase from spinal cord tissue using electrospray mass spectrometry
    Timothy W Rhoads
    Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331, USA
    Anal Biochem 415:52-8. 2011
    ..SOD1 could be measured in subpicomole amounts and resolved to within 2 Da of the predicted parent mass. The methods can be adapted to quantify modifications to other proteins in vivo that can be resolved by mass spectrometry...
  2. pmc Using theoretical protein isotopic distributions to parse small-mass-difference post-translational modifications via mass spectrometry
    Timothy W Rhoads
    Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331, USA
    J Am Soc Mass Spectrom 24:115-24. 2013
    ..Although techniques like ICP-MS can measure total metal in solution, this is the first method able to assess the metal-binding and sulfhydryl reduction of SOD1 at the individual subunit level and is applicable to many other proteins...
  3. pmc Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SOD(G93A) mice co-expressing the Copper-Chaperone-for-SOD
    Jared R Williams
    Linus Pauling Institute, Department of Biochemistry and Biophysics, Oregon State University, United States
    Neurobiol Dis 89:1-9. 2016
    ..All ALS patients also express human CCS, raising the hope that familial SOD ALS patients could respond to CuATSM treatment similarly to the CCSxSOD mice. ..