Srinivasa R Nagalla

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. pmc Genotoxicants target distinct molecular networks in neonatal neurons
    Glen E Kisby
    Center for Research on Occupational and Environmental Toxicology CROET, Oregon Health and Science University, Portland, Oregon 97239, USA
    Environ Health Perspect 114:1703-12. 2006
  2. ncbi request reprint Proteomic analysis of maternal serum in down syndrome: identification of novel protein biomarkers
    Srinivasa R Nagalla
    Department of Pediatrics, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Proteome Res 6:1245-57. 2007
  3. ncbi request reprint Identification of novel protein biomarkers of preterm birth in human cervical-vaginal fluid
    Leonardo Pereira
    Department of Pediatrics and Obstetrics and Gynecology, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Proteome Res 6:1269-76. 2007
  4. ncbi request reprint Comprehensive proteomic analysis of the human amniotic fluid proteome: gestational age-dependent changes
    John Edward A Michaels
    ProteoGenix, Inc, Portland, Oregon 97213, USA
    J Proteome Res 6:1277-85. 2007
  5. doi request reprint Insights into the multifactorial nature of preterm birth: proteomic profiling of the maternal serum glycoproteome and maternal serum peptidome among women in preterm labor
    Leonardo Pereira
    Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, OR, USA
    Am J Obstet Gynecol 202:555.e1-10. 2010
  6. doi request reprint Comprehensive maternal serum proteomic profiles of preclinical and clinical preeclampsia
    Juha Rasanen
    Departments of Obstetrics and Gynecology, Pediatrics, Public Health and Preventive Medicine, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Proteome Res 9:4274-81. 2010
  7. ncbi request reprint Identification of protein modifications using MS/MS de novo sequencing and the OpenSea alignment algorithm
    Brian C Searle
    Department of Pediatrics and School of Dentistry, Oregon Health and Sciences University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239 3098, USA
    J Proteome Res 4:546-54. 2005
  8. ncbi request reprint Comprehensive proteomic analysis of human cervical-vaginal fluid
    Surendra Dasari
    Department of Pediatrics, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Proteome Res 6:1258-68. 2007
  9. pmc Quantification of isotopically overlapping deamidated and 18o-labeled peptides using isotopic envelope mixture modeling
    Surendra Dasari
    Department of Pediatrics, and Department of Biochemistry and Molecular Biology, School of Medicine, Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, Portland, Oregon 97239, USA
    J Proteome Res 8:1263-70. 2009
  10. ncbi request reprint Reliable detection of deamidated peptides from lens crystallin proteins using changes in reversed-phase elution times and parent ion masses
    Surendra Dasari
    Department of Pediatrics, School of Medicine, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239, USA
    J Proteome Res 6:3819-26. 2007

Collaborators

Detail Information

Publications21

  1. pmc Genotoxicants target distinct molecular networks in neonatal neurons
    Glen E Kisby
    Center for Research on Occupational and Environmental Toxicology CROET, Oregon Health and Science University, Portland, Oregon 97239, USA
    Environ Health Perspect 114:1703-12. 2006
    ..Exposure of the brain to environmental agents during critical periods of neuronal development is considered a key factor underlying many neurologic disorders...
  2. ncbi request reprint Proteomic analysis of maternal serum in down syndrome: identification of novel protein biomarkers
    Srinivasa R Nagalla
    Department of Pediatrics, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Proteome Res 6:1245-57. 2007
    ..Further characterization and quantification of these markers in a larger cohort of subjects may provide the basis for new tests for improved DS screening...
  3. ncbi request reprint Identification of novel protein biomarkers of preterm birth in human cervical-vaginal fluid
    Leonardo Pereira
    Department of Pediatrics and Obstetrics and Gynecology, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Proteome Res 6:1269-76. 2007
    ..Further characterization and quantification of these markers in a larger cohort of subjects may provide the basis for new tests for the early, noninvasive positive prediction of SPTB...
  4. ncbi request reprint Comprehensive proteomic analysis of the human amniotic fluid proteome: gestational age-dependent changes
    John Edward A Michaels
    ProteoGenix, Inc, Portland, Oregon 97213, USA
    J Proteome Res 6:1277-85. 2007
    ..A systematic analysis of proteins present both in AF and maternal serum could lead to the development of new noninvasive diagnostic procedures to monitor fetal status...
  5. doi request reprint Insights into the multifactorial nature of preterm birth: proteomic profiling of the maternal serum glycoproteome and maternal serum peptidome among women in preterm labor
    Leonardo Pereira
    Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, OR, USA
    Am J Obstet Gynecol 202:555.e1-10. 2010
    ..The purpose of this study was to identify peptide classifiers that predict spontaneous preterm birth (SPTB) among women in preterm labor (PTL) and to demonstrate specific protein pathways that are activated in PTL...
  6. doi request reprint Comprehensive maternal serum proteomic profiles of preclinical and clinical preeclampsia
    Juha Rasanen
    Departments of Obstetrics and Gynecology, Pediatrics, Public Health and Preventive Medicine, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Proteome Res 9:4274-81. 2010
    ..Angiogenic and antiangiogenic proteins were not significant. We conclude that placental and antiangiogenic proteins are abundant in clinical PE. In preclinical PE, proteomic profile is distinct and different from that in clinical PE...
  7. ncbi request reprint Identification of protein modifications using MS/MS de novo sequencing and the OpenSea alignment algorithm
    Brian C Searle
    Department of Pediatrics and School of Dentistry, Oregon Health and Sciences University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239 3098, USA
    J Proteome Res 4:546-54. 2005
    ..This demonstrates the potential to identify large numbers of known and previously unknown protein modifications in a given tissue using automated data processing algorithms such as OpenSea...
  8. ncbi request reprint Comprehensive proteomic analysis of human cervical-vaginal fluid
    Surendra Dasari
    Department of Pediatrics, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Proteome Res 6:1258-68. 2007
    ..This data set provides a foundation for evaluation of these proteins as potential CVF biomarkers for noninvasive diagnosis of pregnancy-related disorders...
  9. pmc Quantification of isotopically overlapping deamidated and 18o-labeled peptides using isotopic envelope mixture modeling
    Surendra Dasari
    Department of Pediatrics, and Department of Biochemistry and Molecular Biology, School of Medicine, Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, Portland, Oregon 97239, USA
    J Proteome Res 8:1263-70. 2009
    ..The methodology allowed for accurate measurements of ratios of (16)O/(18)O peptides over the wide range of relative abundances...
  10. ncbi request reprint Reliable detection of deamidated peptides from lens crystallin proteins using changes in reversed-phase elution times and parent ion masses
    Surendra Dasari
    Department of Pediatrics, School of Medicine, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239, USA
    J Proteome Res 6:3819-26. 2007
    ..An algorithm was developed to automate this method, and 72 Crystallin deamidation sites, 18 of which were not previously reported in human lens tissue, were detected...
  11. ncbi request reprint Suppression subtractive hybridization and microarray identification of estrogen-regulated hypothalamic genes
    Anna Malyala
    Department of Physiology and Pharmacology, Oregon Health and Science University, Portland, Oregon 97239, USA
    Neurochem Res 29:1189-200. 2004
    ..g., receptors and channels), but also by altering expression of downstream signaling molecules and proteins involved in neurosecretory pathways...
  12. ncbi request reprint High-throughput identification of proteins and unanticipated sequence modifications using a mass-based alignment algorithm for MS/MS de novo sequencing results
    Brian C Searle
    Department of Pediatrics, School of Dentistry, Oregon Health and Sciences University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239 3098, USA
    Anal Chem 76:2220-30. 2004
    ....
  13. doi request reprint Maternal serum glycosylated fibronectin as a point-of-care biomarker for assessment of preeclampsia
    Juha Rasanen
    Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, OR Department of Obstetrics and Gynecology, Oulu University Hospital, Oulu, and Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland
    Am J Obstet Gynecol 212:82.e1-9. 2015
    ..We assessed the association of glycosylated fibronectin (GlyFn) with preeclampsia and its performance in a point-of-care (POC) test...
  14. doi request reprint Glycosylated fibronectin as a first-trimester biomarker for prediction of gestational diabetes
    Juha P Rasanen
    Department of Obstetrics, Oregon Health and Science University, Portland, Oregon, USA
    Obstet Gynecol 122:586-94. 2013
    ..To evaluate the potential clinical utility of serum biomarkers for first-trimester prediction of gestational diabetes mellitus (GDM)...
  15. ncbi request reprint Cloning and characterization of Xen-dorphin prohormone from Xenopus laevis: a new opioid-like prohormone distinct from proenkephalin and prodynorphin
    Patrick Pattee
    Center for Biomarker Discovery, Department of Pediatrics, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Biol Chem 278:53098-104. 2003
    ..Cloning of the Xen-dorphin prohormone provides new evidence for the potential presence of other members in the opioid peptide superfamily...
  16. ncbi request reprint Genetic basis for chamber-specific ventricular phenotypes in the rat infarct model
    Sumeet S Chugh
    Division of Cardiology, Department of Medicine, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    Cardiovasc Res 57:477-85. 2003
    ..The existence of this and other such distinct electrophysiologic phenotypes in right (RV) vs. left ventricles (LV) could be explained by chamber-specific patterns of gene expression...
  17. ncbi request reprint GABAergic system gene expression predicts clinical outcome in patients with neuroblastoma
    Stephen S Roberts
    Department of Pediatrics, NRC 5, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA
    J Clin Oncol 22:4127-34. 2004
    ..Neuroblastoma (NB) is a common childhood malignancy characterized by heterogeneous clinical behavior. The purpose of this study was to identify potential NB biomarkers that may improve outcome prediction...
  18. pmc Proteomic analysis of cervical-vaginal fluid: identification of novel biomarkers for detection of intra-amniotic infection
    Michael G Gravett
    Division of Reproductive Sciences, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA
    J Proteome Res 6:89-96. 2007
    ..Protein expression signatures and immunodetection of specific biomarkers identified can be employed for noninvasive detection of IAI...
  19. ncbi request reprint Standardizing global gene expression analysis between laboratories and across platforms
    Theodore Bammler
    Nat Methods 2:351-6. 2005
    ..These findings indicate that microarray results can be comparable across multiple laboratories, especially when a common platform and set of procedures are used...
  20. ncbi request reprint Diagnosis of intra-amniotic infection by proteomic profiling and identification of novel biomarkers
    Michael G Gravett
    Division of Reproductive Sciences, Oregon National Primate Research Center, Beaverton, Ore, USA
    JAMA 292:462-9. 2004
    ..Intra-amniotic infection (IAI) is commonly associated with preterm birth and adverse neonatal sequelae. Early diagnosis of IAI, however, has been hindered by insensitive or nonspecific tests...
  21. ncbi request reprint Proteomic identification of urinary biomarkers of diabetic nephropathy
    Paturi V Rao
    Department of Endocrinology and Metabolism, Nizam s Institute of Medical Sciences University, Hyderabad, India
    Diabetes Care 30:629-37. 2007
    ..Current diagnosis consists of urine assays of microalbuminuria, which have inadequate specificity and sensitivity...