Ji Yi

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. pmc Can OCT be sensitive to nanoscale structural alterations in biological tissue?
    Ji Yi
    Department of Biomedical Engineering, Northwestern University, 2145 Sheridan Rd, Evanston, IL 60208, USA
    Opt Express 21:9043-59. 2013
  2. ncbi request reprint Analyzing absorption and scattering spectra of micro-scale structures with spectroscopic optical coherence tomography
    Ji Yi
    Biomedical Engineering Department, Northwestern University, 2145 Sheridan Rd, Evanston IL, 60208 USA
    Opt Express 17:13157-67. 2009
  3. doi request reprint Estimation of oxygen saturation from erythrocytes by high-resolution spectroscopic optical coherence tomography
    Ji Yi
    Biomedical Engineering Department, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, USA
    Opt Lett 35:2094-6. 2010
  4. pmc Ultrastructural alterations in field carcinogenesis measured by enhanced backscattering spectroscopy
    Andrew J Radosevich
    Northwestern University, Department of Biomedical Engineering, Tech E310, 2145 Sheridan Road, Evanston, Illinois 60208
    J Biomed Opt 18:097002. 2013
  5. pmc Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation
    Ji Yi
    Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA
    Light Sci Appl 4:. 2015
  6. pmc Spatially resolved optical and ultrastructural properties of colorectal and pancreatic field carcinogenesis observed by inverse spectroscopic optical coherence tomography
    Ji Yi
    Northwestern University, Department of Biomedical Engineering, 2145 Sheridan Road, Evanston, Illinois 60208
    J Biomed Opt 19:36013. 2014
  7. pmc Measurement of the spatial backscattering impulse-response at short length scales with polarized enhanced backscattering
    Andrew J Radosevich
    Biomedical Engineering, Northwestern University, Evanston, Illinois 60208, USA
    Opt Lett 36:4737-9. 2011
  8. pmc Visible-light optical coherence tomography for retinal oximetry
    Ji Yi
    Department of Biomedical Engineering, Northwestern University, Evanston, Illinois 60208, USA
    Opt Lett 38:1796-8. 2013
  9. pmc A combined method to quantify the retinal metabolic rate of oxygen using photoacoustic ophthalmoscopy and optical coherence tomography
    Wei Song
    1 Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA 2 Department of Physics, Harbin Institute of Technology, 92 West Da Zhi Street Nangang District, Harbin, Heilongjiang 150080, China 3
    Sci Rep 4:6525. 2014
  10. pmc Structural length-scale sensitivities of reflectance measurements in continuous random media under the Born approximation
    Andrew J Radosevich
    Biomedical Engineering, Northwestern University, Evanston, Illinois 60208, USA
    Opt Lett 37:5220-2. 2012

Collaborators

Detail Information

Publications24

  1. pmc Can OCT be sensitive to nanoscale structural alterations in biological tissue?
    Ji Yi
    Department of Biomedical Engineering, Northwestern University, 2145 Sheridan Rd, Evanston, IL 60208, USA
    Opt Express 21:9043-59. 2013
    ..Finally, the 3D imaging capability of ISOCT is demonstrated with ex vivo rat buccal and human colon samples...
  2. ncbi request reprint Analyzing absorption and scattering spectra of micro-scale structures with spectroscopic optical coherence tomography
    Ji Yi
    Biomedical Engineering Department, Northwestern University, 2145 Sheridan Rd, Evanston IL, 60208 USA
    Opt Express 17:13157-67. 2009
    ..Two different types of microspheres in gel phantom are discriminated based on their distinguished absorbent feature...
  3. doi request reprint Estimation of oxygen saturation from erythrocytes by high-resolution spectroscopic optical coherence tomography
    Ji Yi
    Biomedical Engineering Department, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, USA
    Opt Lett 35:2094-6. 2010
    ..The result shows a reliable linear association between the SaO(2) derived from SOCT and the DS measurement, indicating this methodology has potential on in vivo applications to evaluate blood oxygenation...
  4. pmc Ultrastructural alterations in field carcinogenesis measured by enhanced backscattering spectroscopy
    Andrew J Radosevich
    Northwestern University, Department of Biomedical Engineering, Tech E310, 2145 Sheridan Road, Evanston, Illinois 60208
    J Biomed Opt 18:097002. 2013
    ..Second, these changes are predominantly attributable to a reduction in the presence of subdiffractional structures. Third, similar trends are seen for both cancer types, suggesting a common progression of structural alterations in each...
  5. pmc Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation
    Ji Yi
    Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA
    Light Sci Appl 4:. 2015
    ..We believe that vis-OCT has the potential to reveal the fundamental role of oxygen metabolism in various retinal diseases...
  6. pmc Spatially resolved optical and ultrastructural properties of colorectal and pancreatic field carcinogenesis observed by inverse spectroscopic optical coherence tomography
    Ji Yi
    Northwestern University, Department of Biomedical Engineering, 2145 Sheridan Road, Evanston, Illinois 60208
    J Biomed Opt 19:36013. 2014
    ..We further verified that the chromatin clumping in epithelial cells and collagen cross-linking caused D to increase in vitro and could be among the mechanisms responsible for the observed changes in epithelium and stroma, respectively...
  7. pmc Measurement of the spatial backscattering impulse-response at short length scales with polarized enhanced backscattering
    Andrew J Radosevich
    Biomedical Engineering, Northwestern University, Evanston, Illinois 60208, USA
    Opt Lett 36:4737-9. 2011
    ..We conclude by demonstrating the extraordinary sensitivity of our technique to the shape of the scattering phase function, including higher order shape parameters than the anisotropy factor (or first moment)...
  8. pmc Visible-light optical coherence tomography for retinal oximetry
    Ji Yi
    Department of Biomedical Engineering, Northwestern University, Evanston, Illinois 60208, USA
    Opt Lett 38:1796-8. 2013
    ..We found that averaged sO(2) values in arterial and venous bloods were 95% and 72%, respectively...
  9. pmc A combined method to quantify the retinal metabolic rate of oxygen using photoacoustic ophthalmoscopy and optical coherence tomography
    Wei Song
    1 Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA 2 Department of Physics, Harbin Institute of Technology, 92 West Da Zhi Street Nangang District, Harbin, Heilongjiang 150080, China 3
    Sci Rep 4:6525. 2014
    ..86 ± 70.23 nl/minute. This quantitative method may shed new light on both fundamental research and clinical care in ophthalmology in the future...
  10. pmc Structural length-scale sensitivities of reflectance measurements in continuous random media under the Born approximation
    Andrew J Radosevich
    Biomedical Engineering, Northwestern University, Evanston, Illinois 60208, USA
    Opt Lett 37:5220-2. 2012
    ..9 nm to 2.07 μm (i.e., λ/13 to 3λ), μb is sensitive from 26.7 to 320 nm (i.e., λ/24 to λ/2), and the spatial reflectance profile is sensitive from 30.8 nm to 2.71 μm (i.e., λ/21 to 4λ)...
  11. pmc Optical Detection of Early Damage in Retinal Ganglion Cells in a Mouse Model of Partial Optic Nerve Crush Injury
    Ji Yi
    Department of Biomedical Engineering, Northwestern University, Evanston, Illinois, United States
    Invest Ophthalmol Vis Sci 57:5665-5671. 2016
    ..This study aims to test whether ELBS can detect early damage in retinal ganglion cells (RGCs)...
  12. pmc Measuring retinal blood flow in rats using Doppler optical coherence tomography without knowing eyeball axial length
    Wenzhong Liu
    Department of Biomedical Engineering, Northwestern University, Evanston, Illinois 60208
    Med Phys 42:5356-62. 2015
    ..The authors plan to develop a Doppler OCT method that can measure the total retinal blood flow rate without requiring the eyeball axial length...
  13. pmc Characterization of malignant brain tumor using elastic light scattering spectroscopy
    Jianmin Gong
    Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA
    Dis Markers 25:303-12. 2008
    ..We also demonstrate that all three classification methods discriminate between tumor and normal tissue and have the potential to identify and quantitatively characterize tumor-infiltrated brain tissues...
  14. pmc Using electron microscopy to calculate optical properties of biological samples
    Wenli Wu
    Applied Physics Program, Northwestern University, Evanston, Illinois 60208, USA
    Biomed Opt Express 7:4749-4762. 2016
    ..The results show strong agreement with an independent study. This method provides a new way to extract the true phase function of biological samples and provides an independent validation for optical property measurement techniques...
  15. pmc Super-resolution two-photon microscopy via scanning patterned illumination
    Ben E Urban
    Department of Biomedical Engineering, Northwestern University, Evanston, Illinois, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 91:042703. 2015
    ..9 over the corresponding diffraction limit. We further demonstrated super-resolution cellular imaging by 2P-SPIM to image actin cytoskeleton in mammalian cells and three-dimensional imaging in highly scattering retinal tissue. ..
  16. pmc Inner retinal oxygen metabolism in the 50/10 oxygen-induced retinopathy model
    Brian T Soetikno
    Functional Optical Imaging Laboratory, Department of Biomedical Engineering, Northwestern University, Evanston, IL
    Sci Rep 5:16752. 2015
    ..By exploring these biological and metabolic changes in great detail, our study provides an improved understanding of the pathophysiology of OIR model. ..
  17. pmc Fractal Characterization of Chromatin Decompaction in Live Cells
    Ji Yi
    Department of Biomedical Engineering, Northwestern University, Evanston, Illinois Boston Medical Center, Department of Medicine, Boston University, Boston, Massachusetts
    Biophys J 109:2218-26. 2015
    ..The results were confirmed by transmission electron microscopy and confocal fluorescence microscopy. ..
  18. doi request reprint Sustained release of stromal cell derived factor-1 from an antioxidant thermoresponsive hydrogel enhances dermal wound healing in diabetes
    Yunxiao Zhu
    Biomedical Engineering Department, McCormick School of Engineering and Applied Science, Northwestern University, Evanston, IL, United States
    J Control Release 238:114-22. 2016
    ..In conclusion, sustained release of SDF-1 from PPCN is a promising and easy to use therapeutic strategy to improve the treatment of chronic non-healing DFUs. ..
  19. pmc Automatic retinal vessel segmentation based on active contours method in Doppler spectral-domain optical coherence tomography
    Wenzhong Liu
    Northwestern University, Department of Biomedical Engineering, 2145 Sheridan Road, Evanston, Illinois 60208, USA
    J Biomed Opt 18:16002. 2013
    ..We tested the active contours method segmentation in both controlled phantom and in vivo rodent eye images...
  20. pmc Structured interference optical coherence tomography
    Ji Yi
    Department of Biomedical Engineering, Northwestern University, Evanston, Illinois 60208, USA
    Opt Lett 37:3048-50. 2012
    ..5 μm, surpassing the diffraction limit ~9.6 μm as in conventional Fourier-domain optical coherence tomography. SIOCT was demonstrated on phantoms and ex vivo adipose tissues...
  21. pmc Long-Term Protection of Retinal Ganglion Cells and Visual Function by Brain-Derived Neurotrophic Factor in Mice With Ocular Hypertension
    Liang Feng
    Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States 2Department of Neurobiology, Weinberg College of Arts and Sciences, Northwestern University, Evanston, Illinois, United States
    Invest Ophthalmol Vis Sci 57:3793-802. 2016
    ....
  22. pmc Detection of extracellular matrix modification in cancer models with inverse spectroscopic optical coherence tomography
    Graham L C Spicer
    Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA
    Phys Med Biol 61:6892-6904. 2016
    ..We present a facile technique for the non-invasive, quantitative study of the micro- and nano-scale structure of the extracellular matrix and its host cells...
  23. pmc Investigating femtosecond-laser-induced two-photon photoacoustic generation
    Ben E Urban
    Northwestern University, Department of Biomedical Engineering, Evanston, Illinois 60208, United States
    J Biomed Opt 19:085001. 2014
    ..Finally, we showed three-dimensional two-photon photoacoustic imaging...
  24. pmc Imaging a full set of optical scattering properties of biological tissue by inverse spectroscopic optical coherence tomography
    Ji Yi
    Department of Biomedical Engineering, Northwestern University, Evanston, Illinois 60208, USA
    Opt Lett 37:4443-5. 2012
    ....