Ann Ragin

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. pmc Structural brain alterations can be detected early in HIV infection
    Ann B Ragin
    Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, USA
    Neurology 79:2328-34. 2012
  2. pmc Disease burden in HIV-associated cognitive impairment: a study of whole-brain imaging measures
    A B Ragin
    Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Neurology 63:2293-7. 2004
  3. pmc Platelet decline as a predictor of brain injury in HIV infection
    Ann B Ragin
    Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    J Neurovirol 17:487-95. 2011
  4. pmc Marked relationship between matrix metalloproteinase 7 and brain atrophy in HIV infection
    Ann B Ragin
    Department of Radiology, Northwestern University, 737 N Michigan Avenue, Suite 1600, Chicago, IL 60611 2927, USA
    J Neurovirol 17:153-8. 2011
  5. pmc Biomarkers of neurological status in HIV infection: a 3-year study
    Ann B Ragin
    Department of Radiology, Northwestern University, Chicago, IL 60611, USA
    Proteomics Clin Appl 4:295-303. 2010
  6. pmc Serum matrix metalloproteinase levels correlate with brain injury in human immunodeficiency virus infection
    Ann B Ragin
    Department of Radiology, Northwestern University, Chicago, Illinois 60611 2927, USA
    J Neurovirol 15:275-81. 2009
  7. pmc Monocyte chemoattractant protein-1 correlates with subcortical brain injury in HIV infection
    A B Ragin
    Department of Radiology, The Children s Memorial Research Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Neurology 66:1255-7. 2006
  8. pmc Diffusion tensor imaging of subcortical brain injury in patients infected with human immunodeficiency virus
    Ann B Ragin
    Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 2927, USA
    J Neurovirol 11:292-8. 2005
  9. pmc Prevalence of HIV-associated neurocognitive disorders in the Multicenter AIDS Cohort Study
    Ned Sacktor
    From the Department of Neurology, Johns Hopkins Bayview Medical Center N S, and the Departments of Orthopaedic Surgery R L S and Psychiatry C M, Johns Hopkins University School of Medicine, Baltimore the Department of Epidemiology E S, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD the Department of Psychiatry J T B, University of Pittsburgh, PA the Department of Psychiatry E M, Rush University School of Medicine, Chicago, IL the Department of Radiology A R, Northwestern University, Evanston, IL and the Department of Neurology, David Geffen School of Medicine A L, and the Department of Psychiatry E M, University of California, Los Angeles
    Neurology 86:334-40. 2016
  10. pmc Cohort Profile: Recruitment cohorts in the neuropsychological substudy of the Multicenter AIDS Cohort Study
    James T Becker
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA, Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA, Department of Psychology, Infectious Diseases and Microbiology, University of Pittsburgh, Pittsburgh, PA, USA
    Int J Epidemiol 44:1506-16. 2015

Research Grants

  1. MRI Study of Aggressive Individuals
    Ann Ragin; Fiscal Year: 2003
  2. A Diffusion Tensor Imaging Study of HIV-Dementia
    Ann Ragin; Fiscal Year: 2006

Collaborators

Detail Information

Publications17

  1. pmc Structural brain alterations can be detected early in HIV infection
    Ann B Ragin
    Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, USA
    Neurology 79:2328-34. 2012
    ..Brain changes occurring early in HIV infection are not well characterized. The Chicago Early HIV Infection Study aimed to evaluate the presence and extent of structural brain alterations using quantitative MRI...
  2. pmc Disease burden in HIV-associated cognitive impairment: a study of whole-brain imaging measures
    A B Ragin
    Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Neurology 63:2293-7. 2004
    ....
  3. pmc Platelet decline as a predictor of brain injury in HIV infection
    Ann B Ragin
    Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    J Neurovirol 17:487-95. 2011
    ..Findings from a structural brain imaging substudy of older participants, however, support a possible relationship between platelet decline and reduced gray matter...
  4. pmc Marked relationship between matrix metalloproteinase 7 and brain atrophy in HIV infection
    Ann B Ragin
    Department of Radiology, Northwestern University, 737 N Michigan Avenue, Suite 1600, Chicago, IL 60611 2927, USA
    J Neurovirol 17:153-8. 2011
    ..MMP-7 was also correlated with measures of virologic and cognitive status...
  5. pmc Biomarkers of neurological status in HIV infection: a 3-year study
    Ann B Ragin
    Department of Radiology, Northwestern University, Chicago, IL 60611, USA
    Proteomics Clin Appl 4:295-303. 2010
    ..To evaluate circulating cytokines and chemokines as correlates of the degree of brain injury in individuals with advanced human immunodeficiency virus (HIV) infection...
  6. pmc Serum matrix metalloproteinase levels correlate with brain injury in human immunodeficiency virus infection
    Ann B Ragin
    Department of Radiology, Northwestern University, Chicago, Illinois 60611 2927, USA
    J Neurovirol 15:275-81. 2009
    ..MMPs may influence neurological outcome through involvement in neuroimmune response, blood-brain barrier permeability, leukocyte migration, and MMP-mediated neurotoxicity...
  7. pmc Monocyte chemoattractant protein-1 correlates with subcortical brain injury in HIV infection
    A B Ragin
    Department of Radiology, The Children s Memorial Research Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Neurology 66:1255-7. 2006
    ..MCP-1 levels correlated with tissue status (mean diffusivity) in all examined regions. Plasma markers were also significantly correlated with anisotropy measurements in centrum semiovale (TNF-alpha) and putamen (hematocrit)...
  8. pmc Diffusion tensor imaging of subcortical brain injury in patients infected with human immunodeficiency virus
    Ann B Ragin
    Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 2927, USA
    J Neurovirol 11:292-8. 2005
    ..Findings from this investigation indicate that DTI is a sensitive tool for correlating neuroanatomic pathologic features with specific cognitive deficits in patients with HIV infection...
  9. pmc Prevalence of HIV-associated neurocognitive disorders in the Multicenter AIDS Cohort Study
    Ned Sacktor
    From the Department of Neurology, Johns Hopkins Bayview Medical Center N S, and the Departments of Orthopaedic Surgery R L S and Psychiatry C M, Johns Hopkins University School of Medicine, Baltimore the Department of Epidemiology E S, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD the Department of Psychiatry J T B, University of Pittsburgh, PA the Department of Psychiatry E M, Rush University School of Medicine, Chicago, IL the Department of Radiology A R, Northwestern University, Evanston, IL and the Department of Neurology, David Geffen School of Medicine A L, and the Department of Psychiatry E M, University of California, Los Angeles
    Neurology 86:334-40. 2016
    ..To evaluate the frequency of HIV-associated neurocognitive disorder (HAND) in HIV+ individuals and determine whether the frequency of HAND changed over 4 years of follow-up...
  10. pmc Cohort Profile: Recruitment cohorts in the neuropsychological substudy of the Multicenter AIDS Cohort Study
    James T Becker
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA, Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA, Department of Psychology, Infectious Diseases and Microbiology, University of Pittsburgh, Pittsburgh, PA, USA
    Int J Epidemiol 44:1506-16. 2015
    ..The MACS public data set (PDS) has been available since 1994 and includes baseline and 6-monthly follow-up data. Beginning in October 1995, the PDS has been released annually with new releases superseding previous versions. ..
  11. pmc Comprehensive brain analysis with automated high-resolution magnetization transfer measurements
    Ying Wu
    Radiology, NorthShore University Healthsystem, Evanston, Illinois 60201, USA
    J Magn Reson Imaging 35:309-17. 2012
    ..To enhance the reliability and spatial resolution of magnetization transfer ratio (MTR) measurements for interrogation of subcortical brain regions with an automated volume of interest (VOI) approach...
  12. doi request reprint Accelerated two- and three-dimensional cine MR imaging of the heart by using a 32-channel coil
    Amir H Davarpanah
    Department of Radiology, Northwestern University, Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611, USA
    Radiology 254:98-108. 2010
    ....
  13. pmc Transcriptome analyses identify key cellular factors associated with HIV-1 associated neuropathogenesis in infected men
    Narasimhan J Venkatachari
    aDepartment of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261 bComputer Science Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA, 15217, USA cMolecular Biology Information Service, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15261, USA dComputational Biology and Machine Learning Department, Carnegie Mellon University, Pittsburgh, PA eDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Suite 1600, 737 N Michigan Ave, Chicago, IL 60611, USA fDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21209, USA gDepartment of Neurology, David Geffen School of Medicine, University of California Los Angeles, CA 90095 hDepartment of Psychiatry, Rush University Medical Center, 1645 W Jackson Blvd, Chicago, IL, 60612, USA iDepartment of Neurology, Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, MD, 21209, USA
    AIDS . 2016
    ..We applied novel Systems Biology approaches to identify specific cellular and viral factors and their related pathways that are associated with different stages of HAND...
  14. pmc Whole brain diffusion tensor imaging in HIV-associated cognitive impairment
    Ann B Ragin
    Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    AJNR Am J Neuroradiol 25:195-200. 2004
    ..This investigation evaluated the prognostic significance of whole brain histogram-derived diffusion tensor imaging indices with respect to severity of cognitive impairment and measures of clinical status in cases of HIV...
  15. pmc Mixed membership trajectory models of cognitive impairment in the multicenter AIDS cohort study
    Samantha A Molsberry
    aDepartment of Psychiatry, University of Pittsburgh bDepartment of Statistics, Carnegie Mellon University, Pittsburgh cInfectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania dDepartment of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland eAIDS Healthcare Foundation, Los Angeles fDepartment of Neurology, University of California Los Angeles, California gDepartment of Psychiatry, Rush University School of Medicine, Chicago, Illinois hDepartment of Psychiatry, University of California Los Angeles, California iDepartment of Psychiatry jDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland kDepartment of Radiology Northwestern University, Evanston, Illinois lDepartment of Neurology mDepartment of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    AIDS 29:713-21. 2015
    ..We applied a novel statistical methodology to identify trajectories to cognitive impairment, and factors that affected the 'closeness' of an individual to one of the canonical trajectories...
  16. doi request reprint Rapid whole-brain magnetic resonance imaging with isotropic resolution at 3 Tesla
    Robert R Edelman
    Department of Radiology, Evanston Northwestern Healthcare, Evanston, IL 60201, USA
    Invest Radiol 44:54-9. 2009
    ..Although further clinical study is needed in a larger patient cohort, these initial results suggest substantial clinical promise for the technique...
  17. pmc Single voxel magnetic resonance spectroscopy at 3 Tesla in a memory disorders clinic: early right hippocampal NAA/Cr loss in mildly impaired subjects
    MARIA T CASERTA
    Department of Psychiatry, University of Chicago, Chicago, IL 60637, USA
    Psychiatry Res 164:154-9. 2008
    ..These findings suggest that RH NAA/Cr ratios measured at 3 Tesla may be a sensitive marker of future progression to dementia in a clinically defined population with isolated memory complaints...

Research Grants2

  1. MRI Study of Aggressive Individuals
    Ann Ragin; Fiscal Year: 2003
    ..Data obtained in this study will yield findings regarding brain structures potentially involved in impulsive aggression and provide insights concerning etiological factors in Intermittent Explosive Disorder. ..
  2. A Diffusion Tensor Imaging Study of HIV-Dementia
    Ann Ragin; Fiscal Year: 2006
    ..Experience gained during the proposed award will lay the foundation for further independent investigations of neurobiological factors in HIV-D. ..