Lifang Hou

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. pmc Public Health Impact and Economic Costs of Volkswagen's Lack of Compliance with the United States' Emission Standards
    Lifang Hou
    Department of Preventive Medicine and The Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Int J Environ Res Public Health 13:. 2016
  2. pmc Mitochondrial haplogroups modify the effect of black carbon on age-related cognitive impairment
    Elena Colicino
    Department of Environmental Health, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Environ Health 13:42. 2014
  3. pmc Influence of multiple APOE genetic variants on cognitive function in a cohort of older men - results from the Normative Aging Study
    Diddier Prada
    Department of Environmental Health, Harvard School of Public Health, 665 Huntington Ave, Boston 02115, MA, USA
    BMC Psychiatry 14:223. 2014
  4. doi request reprint White blood cell count in young adulthood and coronary artery calcification in early middle age: coronary artery risk development in young adults (CARDIA) study
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N Lake Shore Dr suite 1400, Chicago, IL, 60611, USA
    Eur J Epidemiol 28:735-42. 2013
  5. pmc Evolutionary age of repetitive element subfamilies and sensitivity of DNA methylation to airborne pollutants
    Hyang Min Byun
    Laboratory of Environmental Epigenetics, Exposure Epidemiology and Risk Program, Harvard School of Public Health, Boston, MA, USA
    Part Fibre Toxicol 10:28. 2013
  6. pmc Effects of airborne pollutants on mitochondrial DNA methylation
    Hyang Min Byun
    Laboratory of Environmental Epigenetics, Exposure Epidemiology and Risk Program, Harvard School of Public Health, Boston, MA 02115, USA
    Part Fibre Toxicol 10:18. 2013
  7. pmc Inhalable particulate matter and mitochondrial DNA copy number in highly exposed individuals in Beijing, China: a repeated-measure study
    Lifang Hou
    Department of Preventive Medicine Feinberg, School of Medicine Northwestern University, Chicago, IL 60611, USA
    Part Fibre Toxicol 10:17. 2013
  8. doi request reprint Surrogate tissue telomere length and cancer risk: shorter or longer?
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N Lake Shore Drive, Chicago, IL 60611, USA
    Cancer Lett 319:130-5. 2012
  9. pmc Air pollution exposure and telomere length in highly exposed subjects in Beijing, China: a repeated-measure study
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N Lake Shore Drive, Chicago, IL 60611, USA
    Environ Int 48:71-7. 2012
  10. pmc Effects of particulate air pollution on blood pressure in a highly exposed population in Beijing, China: a repeated-measure study
    Andrea Baccarelli
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
    Environ Health 10:108. 2011

Collaborators

Detail Information

Publications52

  1. pmc Public Health Impact and Economic Costs of Volkswagen's Lack of Compliance with the United States' Emission Standards
    Lifang Hou
    Department of Preventive Medicine and The Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Int J Environ Res Public Health 13:. 2016
    ..This study highlights the potential impacts of VW vehicles' lack of compliance on the health and well-being of the U.S. ..
  2. pmc Mitochondrial haplogroups modify the effect of black carbon on age-related cognitive impairment
    Elena Colicino
    Department of Environmental Health, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Environ Health 13:42. 2014
    ..The aim of this study was to investigate whether mtDNA haplogroups determined differential susceptibility to cognitive effects of long-term exposure to black carbon (BC), a marker of traffic-related air pollution...
  3. pmc Influence of multiple APOE genetic variants on cognitive function in a cohort of older men - results from the Normative Aging Study
    Diddier Prada
    Department of Environmental Health, Harvard School of Public Health, 665 Huntington Ave, Boston 02115, MA, USA
    BMC Psychiatry 14:223. 2014
    ..APOE is the biomarker with the greatest known influence on cognitive function; however, the effect of complex haplotypes involving polymorphisms rs449647, rs405509, rs440446, rs429358 and rs7412 has never been studied in older populations...
  4. doi request reprint White blood cell count in young adulthood and coronary artery calcification in early middle age: coronary artery risk development in young adults (CARDIA) study
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N Lake Shore Dr suite 1400, Chicago, IL, 60611, USA
    Eur J Epidemiol 28:735-42. 2013
    ..Results are attenuated when other risk factors are accounted for. Our results suggest the possible early involvement of WBC, particularly eosinophils, in the early stages of atherosclerosis...
  5. pmc Evolutionary age of repetitive element subfamilies and sensitivity of DNA methylation to airborne pollutants
    Hyang Min Byun
    Laboratory of Environmental Epigenetics, Exposure Epidemiology and Risk Program, Harvard School of Public Health, Boston, MA, USA
    Part Fibre Toxicol 10:28. 2013
    ..The purpose of the study is to evaluate sensitivity of DNA methylation in differentially‒evolved LINE, Alu, and HERV subfamilies to different types of airborne pollutants...
  6. pmc Effects of airborne pollutants on mitochondrial DNA methylation
    Hyang Min Byun
    Laboratory of Environmental Epigenetics, Exposure Epidemiology and Risk Program, Harvard School of Public Health, Boston, MA 02115, USA
    Part Fibre Toxicol 10:18. 2013
    ..However, no study has yet investigated whether mitochondrial DNA methylation is sensitive to pro-oxidant environmental exposures...
  7. pmc Inhalable particulate matter and mitochondrial DNA copy number in highly exposed individuals in Beijing, China: a repeated-measure study
    Lifang Hou
    Department of Preventive Medicine Feinberg, School of Medicine Northwestern University, Chicago, IL 60611, USA
    Part Fibre Toxicol 10:17. 2013
    ..Mitochondrial DNA copy number (MtDNAcn) is a marker of mitochondrial damage and malfunctioning. We evaluated whether ambient PM exposure affects MtDNAcn in a highly-exposed population in Beijing, China...
  8. doi request reprint Surrogate tissue telomere length and cancer risk: shorter or longer?
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N Lake Shore Drive, Chicago, IL 60611, USA
    Cancer Lett 319:130-5. 2012
    ..In this article, we reviewed the published data on surrogate tissue TL in relation to cancer risks, discussed the possible reasons for the differences in the results and future directions and challenges for this line of research...
  9. pmc Air pollution exposure and telomere length in highly exposed subjects in Beijing, China: a repeated-measure study
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N Lake Shore Drive, Chicago, IL 60611, USA
    Environ Int 48:71-7. 2012
    ..Telomere length (TL) is a biomarker of CVD risk that is modified by inflammation and oxidative stress, two key pathways for PM effects. Whether PM exposure modifies TL is largely unexplored...
  10. pmc Effects of particulate air pollution on blood pressure in a highly exposed population in Beijing, China: a repeated-measure study
    Andrea Baccarelli
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
    Environ Health 10:108. 2011
    ..PM effects on blood pressure (BP) have been investigated as a mechanism mediating cardiovascular risks, but results are still inconsistent. The purpose of our study is to determine the effects of ambient and personal PM exposure on BP...
  11. pmc Environmental chemical exposures and human epigenetics
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Int J Epidemiol 41:79-105. 2012
    ..To complete our discussion, we also briefly summarize the diseases that have been linked to environmental chemicals-related epigenetic changes...
  12. pmc Ambient PM exposure and DNA methylation in tumor suppressor genes: a cross-sectional study
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N, Lakeshore Drive, Chicago, 60611, USA
    Part Fibre Toxicol 8:25. 2011
    ....
  13. pmc Environmental chemicals and microRNAs
    Lifang Hou
    Department of Preventive Medicine, Northwestern University, Chicago, IL, USA
    Mutat Res 714:105-12. 2011
    ....
  14. pmc Anthropometric measurements, physical activity, and the risk of symptomatic gallstone disease in Chinese women
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Ann Epidemiol 19:344-50. 2009
    ....
  15. pmc Airborne particulate matter and mitochondrial damage: a cross-sectional study
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Environ Health 9:48. 2010
    ..Although mitochondria are both the major intracellular source and target of oxidative stress, the effect of PM on mitochondria has never been evaluated in exposed individuals...
  16. pmc Blood leukocyte DNA hypomethylation and gastric cancer risk in a high-risk Polish population
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Int J Cancer 127:1866-74. 2010
    ..Our results indicate that interactions between blood leukocyte DNA hypomethylation and host characteristics may determine gastric cancer risk...
  17. pmc Telomere length in peripheral leukocyte DNA and gastric cancer risk
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, and the Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois 60611, USA
    Cancer Epidemiol Biomarkers Prev 18:3103-9. 2009
    ..pylori positivity, cigarette smoking, and dietary fruit intake. Shortened telomeres increased gastric cancer risk in this high-risk Polish population...
  18. ncbi request reprint COX1 and COX2 polymorphisms and gastric cancer risk in a Polish population
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N Lake Shore Drive, Chicago, IL 60611, USA
    Anticancer Res 27:4243-7. 2007
    ..Although a number of studies on the polymorphisms in COX1 and COX2 genes in association with risks for a number of cancers have been conducted, their relation to gastric cancer has not been well studied...
  19. pmc Altered methylation in tandem repeat element and elemental component levels in inhalable air particles
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois The Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois
    Environ Mol Mutagen 55:256-65. 2014
    ..115, 95% CI: 0.034; 0.196, FDR = 0.042). PM-associated differences in blood tandem-repeat methylation may help detect biological effects of the exposure and identify individuals who may eventually experience higher lung cancer risk...
  20. pmc Genome-wide study of DNA methylation alterations in response to diazinon exposure in vitro
    Xiao Zhang
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Environ Toxicol Pharmacol 34:959-68. 2012
    ..2-fold, q-value=0.002), and some remain functionally unknown. Our results provided direct experimental evidence that diazinon may modify gene promoter DNA methylation levels, which may play a pathological role in cancer development...
  21. pmc DNA methylation of oxidative stress genes and cancer risk in the Normative Aging Study
    Tao Gao
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University Chicago, IL, USA 60611
    Am J Cancer Res 6:553-61. 2016
    ..These results can potentially facilitate the development of early detection biomarkers and new treatments for a variety of cancers. ..
  22. pmc Lifetime risk for cancer death by sex and smoking status: the lifetime risk pooling project
    Andrew Gawron
    Division of Gastroenterology and Hepatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, 680 N Lake Shore Dr, Suite 1400, Chicago, IL 60611, USA
    Cancer Causes Control 23:1729-37. 2012
    ..Understanding how sex and tobacco exposure may modify lifetime risks for cancer mortality is important for effective communication of risk in targeted public health messages...
  23. pmc Genetic variation in sodium-dependent ascorbic acid transporters and risk of gastric cancer in Poland
    Margaret E Wright
    Department of Pathology, University of Illinois at Chicago, Chicago, IL 60612, USA
    Eur J Cancer 45:1824-30. 2009
    ..These findings suggest that genetic variation in SLC23A2 impacts gastric cancer risk, although confirmation in other studies is required...
  24. pmc Blood Epigenetic Age may Predict Cancer Incidence and Mortality
    Yinan Zheng
    Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    EBioMedicine 5:68-73. 2016
    ..We conclude that blood epigenetic age may mirror epigenetic abnormalities related to cancer development, potentially serving as a minimally invasive biomarker for cancer early detection...
  25. pmc Particulate Air Pollution Exposure and Expression of Viral and Human MicroRNAs in Blood: The Beijing Truck Driver Air Pollution Study
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Environ Health Perspect 124:344-50. 2016
    ..MicroRNAs (miRNAs) are post-transcriptional gene suppressors and potential mediators of environmental effects. In addition to human miRNAs, viral miRNAs expressed from latent viral sequences are detectable in human cells...
  26. pmc Lifetime pesticide use and telomere shortening among male pesticide applicators in the Agricultural Health Study
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Environ Health Perspect 121:919-24. 2013
    ..Telomere length (TL) in surrogate tissues may be influenced by environmental exposures...
  27. pmc Polymorphisms in chemokine and receptor genes and gastric cancer risk and survival in a high risk Polish population
    Andrew J Gawron
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N Lake Shore Drive, Chicago, IL 60611, USA
    Scand J Gastroenterol 46:333-40. 2011
    ..To examine if genetic variations in chemokine receptor and ligand genes are associated with gastric cancer risk and survival...
  28. pmc DNA methylation alterations in response to pesticide exposure in vitro
    Xiao Zhang
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    Environ Mol Mutagen 53:542-9. 2012
    ..Further studies in other cell types and human samples are required, as well as determining the impact of these methylation changes on gene expression...
  29. pmc Prospective changes in global DNA methylation and cancer incidence and mortality
    Brian T Joyce
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N Lake Shore Drive, Suite 1400, Chicago, IL 60611, USA
    Br J Cancer 115:465-72. 2016
    ..Methylation of repetitive elements Alu and LINE-1 in humans is considered a surrogate for global DNA methylation. Previous studies of blood-measured Alu/LINE-1 and cancer risk are inconsistent...
  30. pmc A-clustering: a novel method for the detection of co-regulated methylation regions, and regions associated with exposure
    Tamar Sofer
    Department of Biostatistics, Harvard School of Public Health, 677 Huntington Avenue, SPH2, 4th Floor, Boston, MA 02115, USA, Department of Statistics, University of Connecticut, 215 Glenbrook Road, Storrs, CT 06269, USA, NIEHS, Epidemiology Branch, MD A3 05, PO Box 12233, Research Triangle Park, NC 27709, USA, Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N Lake Shore Drive, Suite 1400 Chicago, IL 60611, USA, Department of Environmental Health and Department of Epidemiology, Harvard School of Public Health, 401 Park Drive, Landmark Ctr Room 415E, Boston, MA 02215, USA
    Bioinformatics 29:2884-91. 2013
    ..It is evident that neighboring CpG sites are often highly correlated with each other, and current literature suggests that clusters of adjacent CpG sites are co-regulated...
  31. pmc Blood methylomics in response to arsenic exposure in a low-exposed US population
    Xin Liu
    1 Mary Ann and J Milburn Smith Child Health Research Program, Ann and Robert H Lurie Children s Hospital of Chicago Research Center, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA 2 Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    J Expo Sci Environ Epidemiol 24:145-9. 2014
    ..Some genes annotated by these 22 CpG sites are known to be involved in As-associated diseases. Replication in larger samples of individuals with low levels of As exposure will be required. ..
  32. doi request reprint Environmental and occupational exposure to chemicals and telomere length in human studies
    Xiao Zhang
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Occup Environ Med 70:743-9. 2013
    ....
  33. doi request reprint Traffic-derived particulate matter exposure and histone H3 modification: A repeated measures study
    Yinan Zheng
    Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA Health Sciences Integrated PhD Program, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Environ Res 153:112-119. 2016
    ..We evaluated whether traffic-derived PM exposure is associated with four types of environmentally inducible global histone H3 modifications...
  34. pmc Linking short tandem repeat polymorphisms with cytosine modifications in human lymphoblastoid cell lines
    Zhou Zhang
    Driskill Graduate Program in Life Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA
    Hum Genet 135:223-32. 2016
    ..Therefore, elucidating these STRP-based mQTL in addition to SNP-based mQTL can provide novel insights into the genetic architectures of complex traits...
  35. pmc Longitudinal Study of DNA Methylation of Inflammatory Genes and Cancer Risk
    Brian Thomas Joyce
    Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois Division of Epidemiology Biostatistics, School of Public Health, University of Illinois Chicago, Chicago, Illinois
    Cancer Epidemiol Biomarkers Prev 24:1531-8. 2015
    ..Our objective was to prospectively and longitudinally examine associations between methylation of four inflammatory genes and cancer risk...
  36. pmc Gene expression variation between African Americans and whites is associated with coronary artery calcification: the multiethnic study of atherosclerosis
    Chiang Ching Huang
    Department of Preventive Medicine, Northwestern University, Chicago, Illinois, USA
    Physiol Genomics 43:836-43. 2011
    ..Our data suggest a connection between immune response and vascular calcification and the result provides a potential mechanistic explanation for the lower prevalence and severity of CAC in African Americans compared with whites...
  37. pmc PGS: a tool for association study of high-dimensional microRNA expression data with repeated measures
    Yinan Zheng
    Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, Institute of Human Genetics, University of Illinois at Chicago, Chicago, IL 60612, Division of Health and Biomedical Informatics, Departments of Preventive Medicine and Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115 and The Robert H Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Bioinformatics 30:2802-7. 2014
    ..However, the commonly used univariate association testing or the site-by-site (SBS) testing may underutilize the longitudinal feature of the data, leading to underpowered results and less biologically meaningful results...
  38. doi request reprint Environmental and occupational exposure to chemicals and telomere length in human studies
    Xiao Zhang
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Postgrad Med J 89:722-8. 2013
    ....
  39. pmc Improved Statistical Analysis for Array CGH-Based DNA Copy Number Aberrations
    Hongmei Jiang
    Department of Statistics, Northwestern University, 2006 Sheridan Road, Evanston, IL 60208, USA
    Cancer Inform 10:249-58. 2011
    ..The relative strengths and weaknesses of the proposed method were demonstrated using both simulation studies and real data analysis of a liver cancer study...
  40. doi request reprint Dietary factors and risk of t(14;18)-defined subgroups of non-Hodgkin lymphoma
    Brian C H Chiu
    Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, 680 North Lake Shore Drive, Suite 1102, Chicago, IL 60611 4402, USA
    Cancer Causes Control 19:859-67. 2008
    ....
  41. doi request reprint Status of cardiovascular health in US children up to 11 years of age: the National Health and Nutrition Examination Surveys 2003-2010
    Hongyan Ning
    From the Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL H N, D R L, L H, L v H, D M L J Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill C M S and Department of Pediatrics, University of Colorado School of Medicine Aurora S R D
    Circ Cardiovasc Qual Outcomes 8:164-71. 2015
    ..Nationally representative prevalence estimates for children under 12 years according to sex and race/ethnicity have not been reported...
  42. pmc Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis
    Pan Du
    Northwestern University Biomedical Informatics Center NUBIC, NUCATS, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    BMC Bioinformatics 11:587. 2010
    ..Both Beta-value and M-value statistics have been used as metrics to measure methylation levels. However, there are no detailed studies of their relations and their strengths and limitations...
  43. ncbi request reprint Sun exposure and non-Hodgkin lymphoma: a population-based, case-control study
    Lori K Soni
    Department of Preventive Medicine, Northwestern University Medical School, Chicago, IL, United States
    Eur J Cancer 43:2388-95. 2007
    ..In conclusion, our data suggest that total hours of sun exposure is associated with a lower risk of NHL, and the inverse association is not modified by vitamin D intake, is stronger among farmer, and may vary by subtypes...
  44. pmc Association between sleep quality and C-reactive protein: results from national health and nutrition examination survey, 2005-2008
    Rong Liu
    Beijing An Zhen Hospital, Capital Medical University, The Key Laboratory of Remodeling related Cardiovascular Diseases, Ministry of Education, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, China Mary Ann and J Milburn Smith Child Health Research Program, Department of Pediatrics, Northwestern University Feinberg School of Medicine and Ann and Robert H Lurie Children s Hospital of Chicago and Children s Hospital of Chicago Research Center, Chicago, Illinois, United States of America
    PLoS ONE 9:e92607. 2014
    ..Our objective was to explore the association between poor sleep quality and hs_CRP in an adult U.S. population...
  45. ncbi request reprint Interleukin-8 polymorphisms are not associated with gastric cancer risk in a Polish population
    Sharon A Savage
    Section of Genomic Variation, Pediatric Oncology Branch, National Cancer Institute, Advanced Technology Center, 8717 Grovemont Circle, Bethesda, MD 20892 4605, USA
    Cancer Epidemiol Biomarkers Prev 15:589-91. 2006
  46. ncbi request reprint Genetic polymorphisms in folate metabolism and the risk of stomach cancer
    Fang Fang Zhang
    Division of Cancer Epidemiology and Genetics, Advanced Technology Center, National Cancer Institute, Gaithersburg, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 16:115-21. 2007
    ..Our study did not identify strong genetic determinants in the folate metabolism pathway for stomach cancer risk...
  47. ncbi request reprint Genetic polymorphisms in alcohol metabolism, alcohol intake and the risk of stomach cancer in Warsaw, Poland
    Fang Fang Zhang
    Department of Epidemiology, School of Public Health, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    Int J Cancer 121:2060-4. 2007
    ..Furthermore, heavy drinkers of alcohol who were genetically prone to accumulate acetaldehyde may face an increased risk of stomach cancer...
  48. pmc Genetic variants in T helper cell type 1, 2 and 3 pathways and gastric cancer risk in a Polish population
    Rajeev Mahajan
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
    Jpn J Clin Oncol 38:626-33. 2008
    ..7-1.3) for C/T and 0.6 (95% CI, 0.3-1.0) T/T carriers compared with C/C carriers (P = 0.03). These results suggest that IL5 rs2069812 and IL7R rs1389832, rs1494556 and rs1494555 polymorphisms may contribute to gastric cancer etiology...
  49. ncbi request reprint Mannose-binding lectin-2 genetic variation and stomach cancer risk
    Andrea Baccarelli
    EPOCA Epidemiology Research Centre, Maggiore Hospital IRCCS Foundation, University of Milan, Milan, Italy
    Int J Cancer 119:1970-5. 2006
    ..6-7.6; p = 0.001). Our findings suggest that the codon 52 D MBL2 variant causing a cysteine > arginine replacement, but not B and C variants producing glycine substitutions, is specifically associated with gastric cancer risk...
  50. ncbi request reprint Commuting physical activity and risk of colon cancer in Shanghai, China
    Lifang Hou
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7240, USA
    Am J Epidemiol 160:860-7. 2004
    ..54 for men; OR = 7.42, 95% CI: 2.84, 10.01 for women). Our results suggest that regular and frequent physical activity over a long period of time protects from colon cancer and significantly modifies the body mass index-associated risk...
  51. ncbi request reprint CYP17 MspA1 polymorphism and risk of biliary tract cancers and gallstones: a population-based study in Shanghai, China
    Lifang Hou
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Rockville MD 20852 7236, USA
    Int J Cancer 118:2847-53. 2006
    ....
  52. ncbi request reprint CYP1A1 Val462 and NQO1 Ser187 polymorphisms, cigarette use, and risk for colorectal adenoma
    Lifang Hou
    Department of Human and Health Services, Division of Cancer Epidemiology and Genetics, Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7240, USA
    Carcinogenesis 26:1122-8. 2005
    ..002). In summary, joint carriage of CYP1A1 Val(462) and NQO1 Ser(187) alleles, particularly in smokers, was related to colorectal adenoma risk, with a propensity for formation of multiple lesions...