Meggan Mackay

Summary

Affiliation: North Shore University Hospital
Country: USA

Publications

  1. doi request reprint Lupus brain fog: a biologic perspective on cognitive impairment, depression, and fatigue in systemic lupus erythematosus
    Meggan Mackay
    Center for Autoimmune and Musculoskeletal Diseases, The Feinstein Institute for Medical Research, 350 Community Drive, Manhasset, NY, 11030, USA
    Immunol Res 63:26-37. 2015
  2. pmc Differences in regional brain activation patterns assessed by functional magnetic resonance imaging in patients with systemic lupus erythematosus stratified by disease duration
    Meggan Mackay
    Center for Autoimmune and Musculoskeletal Disease, The Feinstein Institute for Medical Research, Manhasset, New York, United States of America
    Mol Med 17:1349-56. 2011
  3. pmc Urinary TWEAK as a biomarker of lupus nephritis: a multicenter cohort study
    Noa Schwartz
    Division of Rheumatology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Arthritis Res Ther 11:R143. 2009
  4. pmc Effect of long-term belimumab treatment on B cells in systemic lupus erythematosus: extension of a phase II, double-blind, placebo-controlled, dose-ranging study
    Annett M Jacobi
    Feinstein Institute for Medical Research, Manhasset, New York 11030, USA
    Arthritis Rheum 62:201-10. 2010
  5. pmc Phenotypic characterization of autoreactive B cells--checkpoints of B cell tolerance in patients with systemic lupus erythematosus
    Annett M Jacobi
    The Center for Autoimmune and Musculoskeletal Diseases, Feinstein Institute for Medical Research, North Shore Long Island Jewish Health System, Manhasset, New York, USA
    PLoS ONE 4:e5776. 2009
  6. pmc The impact of vitamin D on dendritic cell function in patients with systemic lupus erythematosus
    Ilan Ben-Zvi
    Division of Autoimmune and Musculoskeletal Disease, Feinstein Institute for Medical Research, Manhasset, New York, United States of America
    PLoS ONE 5:e9193. 2010
  7. pmc Identification of DNA-reactive B cells in patients with systemic lupus erythematosus
    Jie Zhang
    Feinstein Institute for Medical Research, North Shore Long Island Jewish Health System, Manhasset, New York 11030, USA
    J Immunol Methods 338:79-84. 2008
  8. doi request reprint Checkpoints for Autoreactive B Cells in the Peripheral Blood of Lupus Patients Assessed by Flow Cytometry
    Susan Malkiel
    Feinstein Institute for Medical Research, Northwell Health, Manhasset, New York
    Arthritis Rheumatol 68:2210-20. 2016
  9. ncbi request reprint The effect of moderate-dose corticosteroids in preventing severe flares in patients with serologically active, but clinically stable, systemic lupus erythematosus: findings of a prospective, randomized, double-blind, placebo-controlled trial
    Chung E Tseng
    New York University School of Medicine, Hospital for Joint Diseases, New York, New York 10003, USA
    Arthritis Rheum 54:3623-32. 2006
  10. pmc Glutamate receptor biology and its clinical significance in neuropsychiatric systemic lupus erythematosus
    Cynthia Aranow
    Feinstein Institute for Medical Research, 350 Community Drive, Manhasset, NY 11030, USA
    Rheum Dis Clin North Am 36:187-201, x-xi. 2010

Collaborators

Detail Information

Publications12

  1. doi request reprint Lupus brain fog: a biologic perspective on cognitive impairment, depression, and fatigue in systemic lupus erythematosus
    Meggan Mackay
    Center for Autoimmune and Musculoskeletal Diseases, The Feinstein Institute for Medical Research, 350 Community Drive, Manhasset, NY, 11030, USA
    Immunol Res 63:26-37. 2015
    ..This review will focus on the biology of cognition and neuroinflammation in normal circumstances and potential biologic mechanisms for cognitive impairment, depression and fatigue attributable to SLE. ..
  2. pmc Differences in regional brain activation patterns assessed by functional magnetic resonance imaging in patients with systemic lupus erythematosus stratified by disease duration
    Meggan Mackay
    Center for Autoimmune and Musculoskeletal Disease, The Feinstein Institute for Medical Research, Manhasset, New York, United States of America
    Mol Med 17:1349-56. 2011
    ..Our hypothesis is further supported by the lack of correlation between regional brain abnormalities on fMRI and the Systemic Lupus International Collaborating Clinics (SLICC) damage index...
  3. pmc Urinary TWEAK as a biomarker of lupus nephritis: a multicenter cohort study
    Noa Schwartz
    Division of Rheumatology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Arthritis Res Ther 11:R143. 2009
    ..Evidence for the importance of TWEAK in the pathogenesis of lupus nephritis (LN) has been recently introduced. Thus, TWEAK levels may serve as an indication of LN presence and activity...
  4. pmc Effect of long-term belimumab treatment on B cells in systemic lupus erythematosus: extension of a phase II, double-blind, placebo-controlled, dose-ranging study
    Annett M Jacobi
    Feinstein Institute for Medical Research, Manhasset, New York 11030, USA
    Arthritis Rheum 62:201-10. 2010
    ..To understand the effects of long-term BLyS inhibition in human systemic lupus erythematosus (SLE)...
  5. pmc Phenotypic characterization of autoreactive B cells--checkpoints of B cell tolerance in patients with systemic lupus erythematosus
    Annett M Jacobi
    The Center for Autoimmune and Musculoskeletal Diseases, Feinstein Institute for Medical Research, North Shore Long Island Jewish Health System, Manhasset, New York, USA
    PLoS ONE 4:e5776. 2009
    ..This methodology enables us to gain insight into the development and fate of DNA-reactive B cells in individual patients with SLE and paves the way ultimately to permit better and more customized therapies...
  6. pmc The impact of vitamin D on dendritic cell function in patients with systemic lupus erythematosus
    Ilan Ben-Zvi
    Division of Autoimmune and Musculoskeletal Disease, Feinstein Institute for Medical Research, Manhasset, New York, United States of America
    PLoS ONE 5:e9193. 2010
    ..Our goals were to investigate the relationship between vitamin D levels and disease activity in SLE patients and to investigate the effects of vitamin D on DC activation and expression of IFNalpha-regulated genes in vitro...
  7. pmc Identification of DNA-reactive B cells in patients with systemic lupus erythematosus
    Jie Zhang
    Feinstein Institute for Medical Research, North Shore Long Island Jewish Health System, Manhasset, New York 11030, USA
    J Immunol Methods 338:79-84. 2008
    ..This methodology enables us to track the development of autoreactive B cells, which recognize peptide and dsDNA, in individual patients with SLE and permits the isolation of autoreactive B cells for further characterization...
  8. doi request reprint Checkpoints for Autoreactive B Cells in the Peripheral Blood of Lupus Patients Assessed by Flow Cytometry
    Susan Malkiel
    Feinstein Institute for Medical Research, Northwell Health, Manhasset, New York
    Arthritis Rheumatol 68:2210-20. 2016
    ..The aim of this study was to generate an assay to easily identify these B cells and to examine its utility in a study of autoreactive B cells in systemic lupus erythematosus (SLE)...
  9. ncbi request reprint The effect of moderate-dose corticosteroids in preventing severe flares in patients with serologically active, but clinically stable, systemic lupus erythematosus: findings of a prospective, randomized, double-blind, placebo-controlled trial
    Chung E Tseng
    New York University School of Medicine, Hospital for Joint Diseases, New York, New York 10003, USA
    Arthritis Rheum 54:3623-32. 2006
    ..We hypothesized that concomitant elevation of anti-dsDNA and C3a can predict SLE activity in patients with stable or inactive disease and that short-term treatment with corticosteroids can avert flares...
  10. pmc Glutamate receptor biology and its clinical significance in neuropsychiatric systemic lupus erythematosus
    Cynthia Aranow
    Feinstein Institute for Medical Research, 350 Community Drive, Manhasset, NY 11030, USA
    Rheum Dis Clin North Am 36:187-201, x-xi. 2010
    ..These studies suggest that an anatomic classification scheme for neuropsychiatric SLE may facilitate research on etiopathogenesis and the design of clinical trials...
  11. pmc Selective dysregulation of the FcgammaIIB receptor on memory B cells in SLE
    Meggan Mackay
    Department of Medicine, Columbia University Medical Center, New York, NY 10032, USA
    J Exp Med 203:2157-64. 2006
    ....
  12. doi request reprint Cognitive and emotional abnormalities in systemic lupus erythematosus: evidence for amygdala dysfunction
    Philip Watson
    The Graduate Center and Queens College, City University of New York, Flushing, NY, USA
    Neuropsychol Rev 22:252-70. 2012
    ....