Joseph Wang

Summary

Affiliation: New Mexico State University
Country: USA

Publications

  1. ncbi request reprint Nonaqueous electrophoresis microchip separations: conductivity detection in UV-absorbing solvents
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003, USA
    Anal Chem 75:341-5. 2003
  2. ncbi request reprint Capillary electrophoresis microchip with a carbon nanotube-modified electrochemical detector
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003, USA
    Anal Chem 76:298-302. 2004
  3. ncbi request reprint Bulk modification of polymeric microfluidic devices
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA
    Lab Chip 5:226-30. 2005
  4. ncbi request reprint Movable contactless-conductivity detector for microchip capillary electrophoresis
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003, USA
    Anal Chem 75:4475-9. 2003
  5. ncbi request reprint Encoded beads for electrochemical identification
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003, USA
    Anal Chem 75:4667-71. 2003
  6. ncbi request reprint Hot-wire amperometric monitoring of flowing streams
    J Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA
    Talanta 50:1205-10. 2000
  7. doi request reprint Microchip capillary electrophoresis with electrochemical detector for fast measurements of aromatic amino acids
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA
    Talanta 60:1239-44. 2003
  8. ncbi request reprint Measurements of chemical warfare agent degradation products using an electrophoresis microchip with contactless conductivity detector
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003, USA
    Anal Chem 74:6121-5. 2002
  9. ncbi request reprint Dual conductivity/amperometric detection system for microchip capillary electrophoresis
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003, USA
    Anal Chem 74:5919-23. 2002
  10. ncbi request reprint Flow injection amperometric detection of OP nerve agents based on an organophosphorus-hydrolase biosensor detector
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA
    Biosens Bioelectron 18:255-60. 2003

Collaborators

Detail Information

Publications113 found, 100 shown here

  1. ncbi request reprint Nonaqueous electrophoresis microchip separations: conductivity detection in UV-absorbing solvents
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003, USA
    Anal Chem 75:341-5. 2003
    ..Calibration and precision experiments indicate a linear and reproducible response. Such use of organic solvents can benefit microchip separations through extended scope (toward nonpolar solutes) and tunable selectivity...
  2. ncbi request reprint Capillary electrophoresis microchip with a carbon nanotube-modified electrochemical detector
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003, USA
    Anal Chem 76:298-302. 2004
    ..The broad and significant catalytic activity exhibited by CNT-based CE detectors indicates great promise for a wide range of bioanalytical and environmental applications...
  3. ncbi request reprint Bulk modification of polymeric microfluidic devices
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA
    Lab Chip 5:226-30. 2005
    ..The bulk-modified devices exhibit reproducible and stable EOF behavior. The one step fabrication/modification protocol should further facilitate the widespread production of high-performance plastic microchip devices...
  4. ncbi request reprint Movable contactless-conductivity detector for microchip capillary electrophoresis
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003, USA
    Anal Chem 75:4475-9. 2003
    ..These and other improvements in the analytical performance and insights into the separation process are illustrated in connection with the detection of low-energy ionic explosives and nerve agent degradation products...
  5. ncbi request reprint Encoded beads for electrochemical identification
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003, USA
    Anal Chem 75:4667-71. 2003
    ..Factors affecting the preparation of such identification layers were optimized...
  6. ncbi request reprint Hot-wire amperometric monitoring of flowing streams
    J Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA
    Talanta 50:1205-10. 2000
    ..The minimal flow rate dependence observed with the heated electrode should benefit the on-line monitoring of streams with fluctuated natural convection, as well as various in-situ remote sensing applications...
  7. doi request reprint Microchip capillary electrophoresis with electrochemical detector for fast measurements of aromatic amino acids
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA
    Talanta 60:1239-44. 2003
    ..D. of less than 5% for both migration times and peak currents (n=8). It should be useful for the analysis of aromatic amino acids, as desired for life sciences...
  8. ncbi request reprint Measurements of chemical warfare agent degradation products using an electrophoresis microchip with contactless conductivity detector
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003, USA
    Anal Chem 74:6121-5. 2002
    ....
  9. ncbi request reprint Dual conductivity/amperometric detection system for microchip capillary electrophoresis
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003, USA
    Anal Chem 74:5919-23. 2002
    ..The behavior of the dual detector is comparable with those of the individual detectors. Such a dual electrochemical detection system is easy to implement and requires inherently portable low-cost instrumentation...
  10. ncbi request reprint Flow injection amperometric detection of OP nerve agents based on an organophosphorus-hydrolase biosensor detector
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA
    Biosens Bioelectron 18:255-60. 2003
    ..S.D. of 3.6% for 20 successive injections of a 1.0 microM paraoxon solution). The OPH-biosensor flow detector offers great promise for rapid field screening of OP pesticides and nerve agents...
  11. ncbi request reprint Microchip-based amperometric immunoassays using redox tracers
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA
    Electrophoresis 23:3744-9. 2002
    ..5 x 10(-12) and 1 x1 0(-6) g/mL, respectively. Such use of redox labels for chip-based amperometric immunoassay protocols offers considerable promise for decentralized clinical or environmental testing...
  12. ncbi request reprint A chip-based capillary electrophoresis-contactless conductivity microsystem for fast measurements of low-explosive ionic components
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces 88003, USA
    Analyst 127:719-23. 2002
    ..The new microsystem offers great promise for monitoring explosive-related ions at the sample source, with significant advantages of speed/warning, efficiency, cost, or sample size...
  13. ncbi request reprint Dual enzyme electrochemical coding for detecting DNA hybridization
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces 88000, USA
    Analyst 127:1279-82. 2002
    ..Prospects for electrochemical coding of multiple DNA targets are discussed...
  14. ncbi request reprint Microchip capillary electrophoresis with amperometric detection for rapid separation and detection of seleno amino acids
    Joseph Wang
    Departments of Chemical and Materials Engineering and Chemistry and Biochemistry, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA
    J Chromatogr A 1091:177-82. 2005
    ..The new microchip protocol offers great promise for a wide range of food applications requiring fast measurements and negligible sample consumption...
  15. ncbi request reprint Oxygen-independent poly(dimethylsiloxane)-based carbon-paste glucose biosensors
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA
    Biosens Bioelectron 17:999-1003. 2002
    ..On-line continuous testing indicates favorable dynamic properties with no carry-over effects over the physiological and pathophysiological range (3-12 mM glucose)...
  16. ncbi request reprint Microchip capillary electrophoresis with electrochemical detection of thiol-containing degradation products of V-type nerve agents
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003, USA
    Anal Chem 76:4721-6. 2004
    ..The favorable analytical performance makes the new microfluidic device attractive for addressing the needs of various security scenarios...
  17. ncbi request reprint Microfabricated electrophoresis chip for bioassay of renal markers
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003, USA
    Anal Chem 75:525-9. 2003
    ..Applicability to urine samples is demonstrated. Such a multianalyte microchip detection device would allow renal function testing to be performed more rapidly, easily, and economically in the point-of-care setting...
  18. ncbi request reprint Carbon-nanotube-modified electrodes for amplified enzyme-based electrical detection of DNA hybridization
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA
    Biosens Bioelectron 20:995-1000. 2004
    ..The attractive performance characteristics of the new multi-amplification electrochemical detection of DNA hybridization are reported in connection to the detection of nucleic acid sequences related to the breast cancer BRCA1 gene...
  19. ncbi request reprint Microchip capillary electrophoresis with a boron-doped diamond electrode for rapid separation and detection of purines
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Box 30001 Dept 3C, Las Cruces, NM 88003, USA
    J Chromatogr A 1022:207-12. 2004
    ..The new microchip protocol offers great promise for a wide range of bioanalytical applications involving assays of purines and purine-containing compounds...
  20. ncbi request reprint On-chip integration of enzyme and immunoassays: simultaneous measurements of insulin and glucose
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003
    J Am Chem Soc 125:8444-5. 2003
    ..36%) for the insulin/glucose ratio. The resulting biochip allows simultaneous testing for insulin and glucose to be performed more rapidly, easily, and economically, and hence it holds great promise for improved management of diabetes...
  21. ncbi request reprint Electrophoretic microchip with dual-opposite injection for simultaneous measurements of anions and cations
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA
    Electrophoresis 24:3728-34. 2003
    ..The attractive behavior of the dual-opposite injection microchip offers great promise for a wide range of applications, including "total ion analysis" of various samples...
  22. ncbi request reprint Carbon nanotube/teflon composite electrochemical sensors and biosensors
    Joseph Wang
    Department of Chemistry, New Mexico State University, Las Cruces 88003, USA
    Anal Chem 75:2075-9. 2003
    ..The preparation of CNT/Teflon composites overcomes a major obstacle for creating CNT-based biosensing devices and expands the scope of CNT-based electrochemical devices...
  23. ncbi request reprint Electrochemical coding technology for simultaneous detection of multiple DNA targets
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003 8001, USA
    J Am Chem Soc 125:3214-5. 2003
    ..The new electrochemical coding is expected to bring new capabilities for DNA diagnostics, and for bioanalysis, in general...
  24. ncbi request reprint Microchip capillary electrophoresis coupled with a boron-doped diamond electrode-based electrochemical detector
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003, USA
    Anal Chem 75:935-9. 2003
    ..The attractive properties of BDD make it very promising material for electrochemical detection in CE microchip systems and other micromachined flow analyzers...
  25. ncbi request reprint Solubilization of carbon nanotubes by Nafion toward the preparation of amperometric biosensors
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA
    J Am Chem Soc 125:2408-9. 2003
    ..05 V vs Ag/AgCl) biosensing of glucose. These findings open the door for using CNT in a wide range of chemical sensors and nanoscale electronic devices...
  26. ncbi request reprint Capillary electrophoresis-electrochemistry microfluidic system for the determination of organic peroxides
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces 88003, USA
    J Chromatogr A 952:249-54. 2002
    ..35-3.12%; n = 12) reflects the negligible electrode passivation. Such a "lab-on-a-chip" device should be attractive for on-site analysis of organic peroxides, as desired for environmental screening and industrial monitoring...
  27. ncbi request reprint Amperometric biosensors for clinical and therapeutic drug monitoring: a review
    J Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces 88003, USA
    J Pharm Biomed Anal 19:47-53. 1999
    ..This review focuses on the current state of amperometric enzyme electrodes for biomedicine, with emphasis on recent advances, challenges and trends...
  28. ncbi request reprint Real-time monitoring of enzymatic cleavage of nucleic acids using a quartz crystal microbalance
    J Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces 88003, USA
    Bioelectrochem Bioenerg 48:477-80. 1999
    ..These observations indicate great promise for using QCM for elucidating the interactions of nucleic acids with enzymes, and for enhancing the power of hybridization biosensors...
  29. ncbi request reprint On-demand electrochemical release of DNA from gold surfaces
    J Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces 88003, USA
    Bioelectrochemistry 52:111-4. 2000
    ..5-microm radius) is demonstrated in connection with voltammetric blocking experiments. We expect that such on-demand electrochemical release would be a useful addition to the arsenal of nonviral gene delivery routes...
  30. ncbi request reprint Stripping analysis of nucleic acids at a heated carbon paste electrode
    J Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces 88003, USA
    Anal Chem 72:3752-6. 2000
    ..5 mg/L. Such electrode heating technology offers great promise for various applications involving thermal manipulations of nucleic acids...
  31. ncbi request reprint Magnetic bead-based label-free electrochemical detection of DNA hybridization
    J Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces 88003, USA
    Analyst 126:2020-4. 2001
    ..The characterization, optimization and advantages of the genomagnetic label-free electrical protocol are illustrated below for assays of DNA sequences related to the breast-cancer BRCA1 gene...
  32. ncbi request reprint Towards disposable lab-on-a-chip: poly(methylmethacrylate) microchip electrophoresis device with electrochemical detection
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA
    Electrophoresis 23:596-601. 2002
    ..Such coupling of low-cost PMMA-based microchips with thick-film electrochemical detectors holds great promise for mass production of single-use micrototal analytical systems...
  33. ncbi request reprint Processible polyaniline as an advanced potentiometric pH transducer. Application to biosensors
    A A Karyakin
    Faculty of Chemistry of M V Lomonosov Moscow State University, Russia
    Anal Chem 71:2534-40. 1999
    ..The attractive performance characteristics are advantageous over those of existing pH sensors and offer great promise for sensing and biosensing applications...
  34. ncbi request reprint DNA-based amplified bioelectronic detection and coding of proteins
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA
    Angew Chem Int Ed Engl 43:2158-61. 2004
  35. pmc From DNA biosensors to gene chips
    J Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA
    Nucleic Acids Res 28:3011-6. 2000
    ..While the use of DNA biosensors and gene chips is at an early stage, such devices are expected to have an enormous effect on future DNA diagnostics...
  36. ncbi request reprint Magnetically-induced solid-state electrochemical detection of DNA hybridization
    Joseph Wang
    New Mexico State University, Department of Chemistry and Biochemistry, Las Cruces, New Mexico 88003, USA
    J Am Chem Soc 124:4208-9. 2002
    ..Such direct electrical detection of DNA/metal-particle assemblies can bring new capabilities to the detection of DNA hybridization, and could be applied to other bioaffinity assays...
  37. ncbi request reprint Single-channel microchip for fast screening and detailed identification of nitroaromatic explosives or organophosphate nerve agents
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces 88003, USA
    Anal Chem 74:1187-91. 2002
    ..Ultimately, such development will lead to the creation of a field-deployable microanalyzer and will enable transporting the forensic laboratory to the sample source...
  38. ncbi request reprint Needle-type dual microsensor for the simultaneous monitoring of glucose and insulin
    J Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces 88003, USA
    Anal Chem 73:844-7. 2001
    ..6-4.1%). The combination microsensor holds great promise for real-time measurements of the insulin/glucose ratio and for improved management of diabetes...
  39. pmc Aptamer-based potentiometric measurements of proteins using ion-selective microelectrodes
    Apon Numnuam
    Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA
    Anal Chem 80:707-12. 2008
    ..14 nM corresponding to 28 fmol of analyte. The results show great promise for the potentiometric determination of proteins at very low concentrations in microliter samples...
  40. ncbi request reprint Biocatalytically induced formation of cupric ferrocyanide nanoparticles and their application for electrochemical and optical biosensing of glucose
    Joseph Wang
    Department of Chemical and Materials Engineering, Center for Bioelectronics and Biosensors, Biodesign Institute, Arizona State University, Tempe, Arizona 85287 5801, USA
    Small 2:129-34. 2006
    ..This concept can readily be expanded for monitoring a wide range of biocatalytic processes involving the ferricyanide electron acceptor...
  41. ncbi request reprint Metal/Conducting-polymer composite nanowires
    Samantha A Meenach
    Department of Chemical Engineering and Chemistry and Biochemistry, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA
    Small 3:239-43. 2007
  42. ncbi request reprint Contactless conductivity detector for microchip capillary electrophoresis
    Martin Pumera
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces 88003, USA
    Anal Chem 74:1968-71. 2002
    ..The advantages associated with the contactless conductivity detection, along with the low cost of the integrated PMMA chip/detection system, should enhance the power and scope of microfluidic analytical devices...
  43. pmc Potentiometric detection of DNA hybridization
    Apon Numnuam
    Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA
    J Am Chem Soc 130:410-1. 2008
  44. ncbi request reprint "One-step" simplified electrochemical sensing of TATP based on its acid treatment
    Rodrigo A A Munoz
    Departments of Chemical Engineering and Chemistry and Biochemistry, Biodesign Institute, Arizona State University, Tempe, AZ 85287 5801, USA
    Analyst 132:560-5. 2007
    ....
  45. ncbi request reprint Adaptive orientation of multifunctional nanowires for magnetic control of bioelectrocatalytic processes
    Oscar A Loaiza
    Department of Chemical Engineering and Chemistry and Biochemistry, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA
    Angew Chem Int Ed Engl 46:1508-11. 2007
  46. ncbi request reprint Nanocrystal-based bioelectronic coding of single nucleotide polymorphisms
    Guodong Liu
    Department of Chemical Engineering, Biodesign Institute, Arizona State University, Tempe, Arizona 85287 6006, USA
    J Am Chem Soc 127:38-9. 2005
    ..The protocol presented should facilitate the rapid, simple, low-cost, and high throughput screening for SNPs...
  47. doi request reprint Carbon-nanotube-induced acceleration of catalytic nanomotors
    Rawiwan Laocharoensuk
    Biodesign Institute, Department of Chemical Engineering, Arizona State University, Tempe, Arizona 85287, USA
    ACS Nano 2:1069-75. 2008
    ..Such development of highly efficient and controllable nanomotors offers great promise for self-powered nanoscale transport and delivery systems...
  48. ncbi request reprint Electrochemical coding for multiplexed immunoassays of proteins
    Guodong Liu
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003, USA
    Anal Chem 76:7126-30. 2004
    ....
  49. doi request reprint Investigation of the enzyme hydrolysis products of the substrates of alkaline phosphatase in electrochemical immunosensing
    Anchana Preechaworapun
    Department of Chemical and Material Engineering, Chemistry and Biochemistry, Biodesign Institute, Arizona State University, Tempe, AZ 85287 5801, USA
    Talanta 76:424-31. 2008
    ..D.<2; n=3), and very low non-specific adsorption...
  50. ncbi request reprint Simultaneous microchip enzymatic measurements of blood lactate and glucose
    Joseph Wang
    Departments of Chemical Engineering and Chemistry and Biochemistry, Biodesign Institute, Arizona State University, Tempe, AZ 85287 5001, USA
    Anal Chim Acta 585:11-6. 2007
    ..Such ability to rapidly separate and quantitate lactate and glucose on a small microchip platform should find important clinical and biotechnological applications...
  51. ncbi request reprint Carbon-nanotube-modified glassy carbon electrodes for amplified label-free electrochemical detection of DNA hybridization
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003, USA
    Analyst 128:912-6. 2003
    ..The performance characteristics of the amplified label-free electrochemical detection of DNA hybridization are reported in connection to measurements of nucleic-acid segments related to the breast-cancer BRCA1 gene...
  52. ncbi request reprint Nanomaterial-based amplified transduction of biomolecular interactions
    Joseph Wang
    Departments of Chemical and Materials Engineering and Chemistry and Biochemistry, Biodesign Institute, Arizona State University, Tempe, Arizona 85287, USA
    Small 1:1036-43. 2005
    ..The implications of such nanoscale materials on amplified biodetection protocols and on the development of modern biosensors are discussed...
  53. ncbi request reprint Quantum-dot/aptamer-based ultrasensitive multi-analyte electrochemical biosensor
    Jacob A Hansen
    Department of Chemical and Material Engineering, Biodesign Institute, Arizona State University, Tempe, AZ 85287 5801, USA
    J Am Chem Soc 128:2228-9. 2006
    ..The new device offers great promise for measuring a large panel of disease markers present at ultralow levels during early stages of the disease progress...
  54. ncbi request reprint Templated one-step synthesis of compositionally encoded nanowire tags
    Joseph Wang
    The Biodesign Institute, Department of Chemical and Materials Engineering, Arizona State University, Tempe, Arizona 85287 5801, USA
    Anal Chem 78:2461-4. 2006
    ..Factors influencing the identification accuracy are evaluated using three-metal (In, Pb, Bi) alloy nanowires, and the relative advantages and disadvantages of the new route are discussed...
  55. doi request reprint Enzymatic nanolithography of polyaniline nanopatterns by using peroxidase-modified atomic force microscopy tips
    Xiliang Luo
    Biodesign Institute, Department of Chemical Engineering, Arizona State University, Tempe, AZ 85287, USA
    Chemistry 15:5191-4. 2009
    ..Scanning of the modified tip in the presence of aniline and hydrogen peroxide is used for biocatalytic patterning of different polyaniline nanostructures (see figure)...
  56. ncbi request reprint Ultrasensitive electrical biosensing of proteins and DNA: carbon-nanotube derived amplification of the recognition and transduction events
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003, USA
    J Am Chem Soc 126:3010-1. 2004
    ..The DNA-linking of CNTs and particles holds promise also for assembling hybrid nanostructures relevant to molecular electronic devices...
  57. ncbi request reprint Microchip capillary electrophoresis with amperometric detection for rapid separation and detection of phenolic acids
    Matteo Scampicchio
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA
    J Chromatogr A 1049:189-94. 2004
    ..An application on a commercial red wine was performed with minimal sample preparation and promising results...
  58. ncbi request reprint Shape-tailored porous gold nanowires: from nano barbells to nano step-cones
    Rawiwan Laocharoensuk
    Biodesign Insititute, Department of Chemical Engineering, Arizona State University, Tempe, Arizona 85287, USA
    ACS Nano 1:403-8. 2007
    ..The new "nanomachining" concept is versatile and could be extended to nanowires of diverse shapes with a variety of properties, generating an attractive assortment of nano-hardware...
  59. ncbi request reprint Biocatalytic carbon paste sensors based on a mediator pasting liquid
    Nathan S Lawrence
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA
    Anal Chem 76:3735-9. 2004
    ..Such use of the electron acceptor as a binder as well as the mediator offers considerable promise for the biosensing of numerous analytes of clinical and environmental significance...
  60. ncbi request reprint Indium microrod tags for electrochemical detection of DNA hybridization
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico, 88003, USA
    Anal Chem 75:6218-22. 2003
    ..The resulting protocol offers great promise for other affinity bioassays, as well as for electrical coding and identification (through the plating of different metal markers and of multimetal redox-encoded tags)...
  61. pmc Amperometric sensing of hydrogen peroxide vapor for security screening
    John Benedet
    The Biodesign Institute and Department of Chemical Engineering, Arizona State University, Tempe, AZ 85287 5801, USA
    Anal Bioanal Chem 395:371-6. 2009
    ..The attractive performance of the new microfabricated PB-based amperometric peroxide vapor sensor indicates great potential for addressing a wide range of security screening and surveillance applications...
  62. pmc Potentiometric biosensing of proteins with ultrasensitive ion-selective microelectrodes and nanoparticle labels
    Karin Y Chumbimuni-Torres
    Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA
    J Am Chem Soc 128:13676-7. 2006
    ..Since potentiometry is expected to largely maintain its analytical characteristics upon reducing the sample volume, it is anticipated that this approach may form the basis for bioassays with attractive detection limits...
  63. ncbi request reprint Nanoparticle-based assays of antioxidant activity
    Matteo Scampicchio
    Biodesign Institute, Arizona State University, Tempe, Arizona 85287 5001, USA
    Anal Chem 78:2060-3. 2006
    ..The highest capacity of reducing gold(III) to gold nanoparticles corresponds to the highest antioxidant activity, consistent with the tendency of phenolic acids to donate electrons...
  64. ncbi request reprint Adaptive nanowires for switchable microchip devices
    Evandro Piccin
    Departments of Chemical Engineering and Chemistry and Biochemistry, Biodesign Institute, Arizona State University, Tempe, Arizona 85287 5801, USA
    Anal Chem 79:4720-3. 2007
    ..The concept can be extended to other microchip functions and stimuli-responsive materials and holds great promise for regulating the operation of microfluidic devices in reaction to specific needs or unforeseen scenarios...
  65. ncbi request reprint Multiple enzyme layers on carbon nanotubes for electrochemical detection down to 80 DNA copies
    Bernard Munge
    Department of Chemical and Materials Engineering, Biodesign Institute, Arizona State University, Tempe, Arizona 85287 5001, USA
    Anal Chem 77:4662-6. 2005
    ..4 aM) and 2000 protein molecules (67 aM), respectively. Given the enormous amplification afforded by the new CNT-LBL biolabel, such route offers great promise for ultrasensitive detection of infectious agents and disease markers...
  66. ncbi request reprint A cytokine immunosensor for multiple sclerosis detection based upon label-free electrochemical impedance spectroscopy
    Jeffrey T La Belle
    Biodesign Institute at Arizona State University, Tempe, AZ 85287 6001, USA
    Biosens Bioelectron 23:428-31. 2007
    ..The cost-effective approach described here can be used for diagnosis of diseases (like MS) with known biomarkers in body fluids and for monitoring physiological levels of biomolecules with healthcare, food, and environmental relevance...
  67. ncbi request reprint Electrocatalytic detection of insulin at RuOx/carbon nanotube-modified carbon electrodes
    Joseph Wang
    Departments of Chemical and Material Engineering, Chemistry and Biochemistry, The Biodesign Institute, Arizona State University, Tempe, AZ 85287 5801, USA
    Anal Chim Acta 581:1-6. 2007
    ..The results suggest great promise for miniaturized sensors and detectors for monitoring insulin...
  68. ncbi request reprint Sensitive and rapid electrochemical bioassay of glycosidase activity
    Tanin Tangkuaram
    The Biodesign Institute and Fulton School of Engineering, Arizona State University, Tempe, AZ 85287 5801, USA
    Analyst 131:889-91. 2006
    ..The attractive characteristics of the new bioassay should facilitate advanced glycomic research and routine clinical diagnostics since glycosidases are associated with various diseases...
  69. ncbi request reprint Carbon-nanotube/copper composite electrodes for capillary electrophoresis microchip detection of carbohydrates
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA
    Analyst 129:512-5. 2004
    ..While the present work has focused on the enhanced CE microchip detection of carbohydrates and amino acids, the CNT/metal-composite electrode route should benefit the detection of other important groups of analytes...
  70. pmc Electrochemical sample matrix elimination for trace-level potentiometric detection with polymeric membrane ion-selective electrodes
    Karin Y Chumbimuni-Torres
    Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA
    Anal Chem 80:6114-8. 2008
    ..This concept is successfully evaluated with cadmium as a model trace element and offers potentiometric detection down to low parts per billion levels in samples containing 0.5 M NaCl background electrolyte...
  71. ncbi request reprint Nucleic-acid immobilization, recognition and detection at chronopotentiometric DNA chips
    J Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces 88003, USA
    Biosens Bioelectron 12:587-99. 1997
    ..Applicability for the detection of sequences from M. tuberculosis and HIV-1 DNAs is illustrated. Such activity in the author's laboratory, aimed at developing DNA-coated screen-printed electrodes, is reviewed...
  72. ncbi request reprint Acid stability of carbon paste enzyme electrodes
    Joseph Wang
    The Biodesign Institute, Department of Chemical and Materials Engineering, Arizona State University, Tempe, Arizona 85287 5801, USA
    Anal Chem 78:7044-7. 2006
    ....
  73. doi request reprint Synthetic nanomotors in microchannel networks: directional microchip motion and controlled manipulation of cargo
    Jared Burdick
    Department of Mechanical and Aerospace Engineering, Arizona State University, Tempe, Arizona 85287 5801, USA
    J Am Chem Soc 130:8164-5. 2008
    ..Such use of synthetic nanomachines can lead to chemically powered versatile laboratory-on-a-chip devices performing a series of tasks simultaneously or sequentially...
  74. ncbi request reprint Enzyme-dispersed carbon-nanotube electrodes: a needle microsensor for monitoring glucose
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA
    Analyst 128:1382-5. 2003
    ..The attractive performance of the new needle electrode offers great promise for continuous monitoring of glucose in connection to the management of diabetes, and for the biosensing of other metabolites...
  75. ncbi request reprint Fast and simple sample introduction for capillary electrophoresis microsystems
    Gang Chen
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA
    Analyst 129:507-11. 2004
    ..Such ability to continuously introduce discrete samples into micrometer channels indicates great promise for high-speed microchip analysis...
  76. ncbi request reprint On-chip enzymatic assays
    Joseph Wang
    Department of Chemistry, New Mexico State University, Las Cruces, NM 88003, USA
    Electrophoresis 23:713-8. 2002
    ..The versatility of such on-chip enzymatic assays offers great promise for decentralized testing of clinically or environmentally important substrates...
  77. ncbi request reprint Highly sensitive electrochemical detection of trace liquid peroxide explosives at a Prussian-blue 'artificial-peroxidase' modified electrode
    Donglai Lu
    The Biodesign Institute and Departments of Chemical Engineering and Chemistry, Arizona State University, Tempe, AZ 85287 5801, USA
    Analyst 131:1279-81. 2006
    ..The electrochemical sensing protocol should facilitate rapid field screening of peroxide explosives...
  78. ncbi request reprint Amplified label-free electrical detection of DNA hybridization
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces 88003, USA
    Analyst 127:383-6. 2002
    ..The copper enhancement holds great promise not only for the detection of DNA hybridization, but also for trace measurement of nucleic acids...
  79. ncbi request reprint Carbon nanotube screen-printed electrochemical sensors
    Joseph Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA
    Analyst 129:1-2. 2004
    ..Such thick-film CNT sensors have a well-defined appearance, are mechanically stable, and exhibit high electrochemical reactivity...
  80. ncbi request reprint Amplified transduction of biomolecular interactions based on the use of nanomaterials
    Joseph Wang
    Biodesign Institute, Department of Chemical Engineering, Arizona State University, Tempe 85287 5801, USA
    Adv Biochem Eng Biotechnol 109:239-54. 2008
    ..The remarkable sensitivity of the new nanomaterial-based sensing protocols opens up the possibility of detecting disease markers, biothreat agents, or infectious agents that cannot be measured by conventional methods...
  81. ncbi request reprint Nanomaterial-based electrochemical biosensors
    Joseph Wang
    Department of Chemical and Materials Engineering, Biodesign Institute, Arizona State University, Tempe, AZ 85287 5001, USA
    Analyst 130:421-6. 2005
    ....
  82. ncbi request reprint Electrochemical detection of amino acids at carbon nanotube and nickel-carbon nanotube modified electrodes
    Randhir P Deo
    Department of Chemistry, New Mexico State University, New Mexico 88003, USA
    Analyst 129:1076-81. 2004
    ..Once again an improved signal was observed at the Ni-CNT electrode compared to nickel deposited upon a bare glassy carbon electrode (Ni-GC)...
  83. ncbi request reprint Electrochemical sensors for environmental monitoring: design, development and applications
    Grady Hanrahan
    Department of Chemistry and Biochemistry, California State University at Los Angeles, Los Angeles, CA 90032, USA
    J Environ Monit 6:657-64. 2004
    ..g. detection limits), microfabrication and remote communication are presented. In addition, modern environmental applications will be discussed and future perspectives considered...
  84. ncbi request reprint Magnetically induced carbon nanotube-mediated control of electrochemical reactivity
    Mustafa Musameh
    Department of Chemical and Materials Engineering, The Biodesign Institute, Arizona State University, Tempe, Arizona 85287, USA
    Langmuir 21:8565-8. 2005
  85. ncbi request reprint Discrete microfluidics with electrochemical detection
    Solitaire Lindsay
    Harrington Department of Bioengineering, Arizona State University, Tempe, AZ 85287, USA
    Analyst 132:412-6. 2007
    ..The new droplet-based electrochemical microfluidic system offers a promising platform for automated clinical diagnostics and drug discovery...
  86. doi request reprint Reliable, rapid and simple voltammetric detection of urea nitrate explosive
    Avi Cagan
    The Biodesign Institute and Departments of Chemical Engineering and Chemistry, Arizona State University, Tempe, AZ 85287 5801, USA
    Analyst 133:585-7. 2008
    ..The new protocol offers great promise for a reliable field detection of UN, with significant advantages of speed, sensitivity, portability, simplicity, and cost...
  87. ncbi request reprint Electrochemical glucose biosensors
    Joseph Wang
    Biodesign Institute, Center for Bioelectronics and Biosensors, Department of Chemical Engineering, Arizona State University, Tempe, AZ 85287 5801, USA
    Chem Rev 108:814-25. 2008
  88. ncbi request reprint Real-time electrochemical monitoring: toward green analytical chemistry
    Joseph Wang
    Department of Chemistry, New Mexico State University, Las Cruces, New Mexico 88003, USA
    Acc Chem Res 35:811-6. 2002
    ..These developments allow the instrument to be taken to the sample (rather than the traditional way of bringing the sample to the laboratory) and hence to ensure effective process or pollution control...
  89. ncbi request reprint Measurement of trace elements in proteins extracted from liver by size exclusion chromatography-inductively coupled plasma-mass spectrometry with a magnetic sector mass spectrometer
    J Wang
    Department of Chemistry, Iowa State University, Ames, Iowa, 50011, USA
    Anal Biochem 288:89-96. 2001
    ..Other elements like Mo, Ca, and Mg are present only in low-molecular-weight proteins or other small molecules...
  90. ncbi request reprint DNA biosensors based on peptide nucleic acid (PNA) recognition layers. A review
    J Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces 88003, USA
    Biosens Bioelectron 13:757-62. 1998
    ..The present review discusses the unique structural, hybridization, and recognition features of PNA probes, along with the opportunities accrued from the use of PNA recognition layers in DNA diagnostics...
  91. ncbi request reprint Monitoring DNA immobilization and hybridization on surfaces by atomic force microscopy force measurements
    J Wang
    Department of Chemistry and Biochemistry, The University of Texas at Austin, 78712, USA
    Anal Chem 73:2207-12. 2001
    ..For ds-DNA, there is a strong interaction which is believed to be due to the association or intercalation of Ru(phen)3(2+) with ds-DNA...
  92. ncbi request reprint Tyrosinase-based ruthenium dispersed carbon paste biosensor for phenols
    J Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces 88003
    Biosens Bioelectron 9:9-15. 1994
    ..The influence of various experimental variables is explored. Fast, sensitive and reproducible flow injection detection of phenolic compounds is illustrated. Analogous improvements are reported for tyrosinase-rich plant tissue electrodes...
  93. ncbi request reprint Metal nanoparticle-based electrochemical stripping potentiometric detection of DNA hybridization
    J Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces 88003, USA
    Anal Chem 73:5576-81. 2001
    ....
  94. ncbi request reprint Organic-phase biosensing of secondary alcohols with a Ta. brockii alcohol dehydrogenase electrode
    J Wang
    Department of Chemistry, New Mexico State University, Las Cruces 88003
    Biosens Bioelectron 9:225-30. 1994
    ..The solvent-induced changes in the enzymatic activity result in an extended linear range. The work expands the scope of organic-phase biosensors towards additional substrates of analytical significance...
  95. ncbi request reprint Combined polymerized chiral micelle and gamma-cyclodextrin for chiral separation in capillary electrophoresis
    J Wang
    Department of Chemistry, Louisiana State University, Baton Rouge 70803, USA
    J Chromatogr A 711:297-304. 1995
    ..In addition, the effects of the antipode (L-SUV), gamma-CD concentration, buffer concentration, organic solvents, and urea concentration on the resolution are also examined...
  96. ncbi request reprint Microseparation chips for performing multienzymatic dehydrogenase/oxidase assays: simultaneous electrochemical measurement of ethanol and glucose
    J Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces 88003, USA
    Anal Chem 73:1296-300. 2001
    ..Factors influencing the reaction, separation, and detection processes are examined and optimized. The applicability of the new multienzyme assay to wine samples is illustrated...
  97. ncbi request reprint Consequences of a modified putative substrate-activation site on catalysis by yeast pyruvate decarboxylase
    J Wang
    Department of Chemistry, Rutgers, The State University of New Jersey, Newark, NJ 07102, USA
    Biochemistry 40:1755-63. 2001
    ..The solvent kinetic isotope effects are compared to those on two related enzymes not subject to substrate activation, Zymomonas mobilis pyruvate decarboxylase and benzoylformate decarboxylase...
  98. ncbi request reprint Synthesis of L-4,4-difluoroglutamic acid via nucleophilic addition to a chiral aldehyde
    Y Ding
    Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA
    J Org Chem 66:6381-8. 2001
    ..Conversion of the difluorinated adducts to L-4,4-difluoroglutamic acid can be accomplished in three steps by Barton-McCombie dehydroxylation and acid hydrolysis...
  99. ncbi request reprint A lysine dehydrogenase-based electrode for biosensing of L-lysine
    E Dempsey
    Department of Chemistry, New Mexico State University, Las Cruces 88003
    Biosens Bioelectron 7:323-7. 1992
    ..9%) and high sample throughout (40 samples per hour). The high specificity offered by this new enzyme is indicated by the lack of interference by other L-amino acids, alcohols or carbohydrates...
  100. ncbi request reprint Glucose biochip: dual analyte response in connection to two pre-column enzymatic reactions
    J Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces 88003, USA
    Analyst 126:1203-6. 2001
    ..The concept can be extended to different target analytes based on the coupling of two pre-column reactions with electrophoretic separation of the reaction products...
  101. ncbi request reprint Electrochemical enzyme immunoassays on microchip platforms
    J Wang
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces 88003, USA
    Anal Chem 73:5323-7. 2001
    ....