Affiliation: New York University School of Medicine
- Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signalingYuliya Pylayeva
Cell Biology Program, Memorial Sloan Kettering Cancer Center MSKCC, New York, New York, USA
J Clin Invest 119:252-66. 2009....
- Analysis of integrin signaling in genetically engineered mouse models of mammary tumor progressionYuliya Pylayeva
Cell Biology Program, Memorial Sloan Kettering Cancer Center, and Sloan Kettering Division, Weill Graduate School of Medical Sciences, Cornell University, New York, New York, USA
Methods Enzymol 426:439-61. 2007..In this chapter, we describe a collection of cell biological and genetic methods that may aid in characterizing the roles of integrin signals in mammary tumorigenesis...
- Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesisWenjun Guo
Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10021 USA
Cell 126:489-502. 2006..These results indicate that beta 4 integrin promotes tumor progression by amplifying ErbB2 signaling and identify beta 4 as a potential target for molecular therapy of breast cancer...