Affiliation: New York University
- Bacterial biota in the human distal esophagusZhiheng Pei
Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
Proc Natl Acad Sci U S A 101:4250-5. 2004..These findings provide evidence for a complex but conserved bacterial population in the normal distal esophagus...
- Molecular analysis of human forearm superficial skin bacterial biotaZhan Gao
Department of Medicine, New York University School of Medicine, New York, NY 10016, USA
Proc Natl Acad Sci U S A 104:2927-32. 2007..4% of all clones. These results show that the bacterial biota in normal superficial skin is highly diverse, with few well conserved and well represented genera, but otherwise low-level interpersonal consensus...
- Bacterial biota in reflux esophagitis and Barrett's esophagusZhiheng Pei
Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
World J Gastroenterol 11:7277-83. 2005..To identify the bacterial flora in conditions such as Barrettos esophagus and reflux esophagitis to determine if they are similar to normal esophageal flora...
- Molecular pathways: pathogenesis and clinical implications of microbiome alteration in esophagitis and Barrett esophagusLiying Yang
Department of Medicine and Pathology, New York University School of Medicine, New York, New York 10010, USA
Clin Cancer Res 18:2138-44. 2012....
- Association between selected oral pathogens and gastric precancerous lesionsChristian R Salazar
Department of Epidemiology and Health Promotion, New York University College of Dentistry, New York, NY, USA
PLoS ONE 8:e51604. 2013..03-0.06). Among individuals with periodontal disease, high levels of colonization of periodontal pathogens are associated with an increased risk of gastric precancerous lesions...
- Substantial alterations of the cutaneous bacterial biota in psoriatic lesionsZhan Gao
Department of Medicine, New York University School of Medicine, New York, New York, United States of America
PLoS ONE 3:e2719. 2008..001), whereas normal skin from the psoriatic patients showed intermediate levels (12.3+/-21.6%). We conclude that psoriasis is associated with substantial alteration in the composition and representation of the cutaneous bacterial biota...
- The effect of H. pylori eradication on meal-associated changes in plasma ghrelin and leptinFritz Francois
New York University Langone Medical Center, New York, NY, USA
BMC Gastroenterol 11:37. 2011..pylori colonization. We prospectively evaluated the effect of H. pylori eradication on meal-associated changes in serum ghrelin and leptin levels, and body weight...
- Sex, body mass index, and dietary fiber intake influence the human gut microbiomeChristine Dominianni
Department of Population Health, New York University School of Medicine, New York, New York, United States of America
PLoS ONE 10:e0124599. 2015..Our findings suggest that sex, BMI, and dietary fiber contribute to shaping the gut microbiome in humans. Better understanding of these relationships may have significant implications for gastrointestinal health and disease prevention. ..
- Urethral adenocarcinoma associated with intestinal-type metaplasia, case report and literature reviewChristopher S Hale
Department of Pathology, New York Harbor Healthcare System, New York University School of Medicine, New York, NY, USA
Int J Clin Exp Pathol 6:1665-70. 2013..When intestinal-type mucosa is present within a urinary tract biopsy, associated malignancy may be present only focally. Thorough sampling and consideration of the differential diagnosis is imperative. ..
- Human gut microbiome and risk for colorectal cancerJiyoung Ahn
Affiliations of authors Division of Epidemiology, Department of Population Health JA, CD, JW, RBH, Department of Pathology ZP, and Department of Medicine ZP, ly, New York University School of Medicine, New York, NY New York University Cancer Institute, New York, NY JA, ZP, CD, JW, RBH Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD RS, JS, JJG Department of Pathology and Laboratory Medicine, New York Veterans Affairs Medical Center, New York, NY ZP
J Natl Cancer Inst 105:1907-11. 2013..17; 95% CI = 1.75 to 15.25) were found in case subjects compared with control subjects. Because of the potentially modifiable nature of the gut bacteria, our findings may have implications for CRC prevention. ..
- Diversity of 5S rRNA genes within individual prokaryotic genomesAnna Pei
New York University College of Arts and Science, New York, NY, USA
FEMS Microbiol Lett 335:11-8. 2012..In total, these findings indicated that there are tight ribosomal constraints on paralogous 5S rRNA genes in a genome despite of the high degree of diversity at the primary structure level...
- Human microbiome and HIV/AIDSDeepak Saxena
Department of Basic Science and Craniofacial Biology, New York University College of Dentistry, New York, NY, USA
Curr HIV/AIDS Rep 9:44-51. 2012....
- Association between oral health and gastric precancerous lesionsChristian R Salazar
Department of Epidemiology and Health Promotion, New York University College of Dentistry, New York, NY 10003, USA
Carcinogenesis 33:399-403. 2012..7%)], independent of potential confounders. Our findings demonstrate that specific oral health conditions and behaviors such as gingival bleeding and tooth flossing are associated with gastric precancerous lesions...
- Inflammation and intestinal metaplasia of the distal esophagus are associated with alterations in the microbiomeLiying Yang
Department of Pathology, New York University School of Medicine, New York, New York, USA
Gastroenterology 137:588-97. 2009..This is the first comprehensive reported correlation between a change in the esophageal microbiome and esophageal diseases...
- Design of 16S rRNA gene primers for 454 pyrosequencing of the human foregut microbiomeCarlos W Nossa
Department of Veterans Affairs New York Harbor Health System, 423 E 23rd Street, New York, NY 10010, USA
World J Gastroenterol 16:4135-44. 2010..To design and validate broad-range 16S rRNA primers for use in high throughput sequencing to classify bacteria isolated from the human foregut microbiome...
- Cigarette smoking and the oral microbiome in a large study of American adultsJing Wu
Division of Epidemiology, Department of Population Health, NYU School of Medicine, New York, NY, USA
ISME J 10:2435-46. 2016..Our findings demonstrate that smoking alters the oral microbiome, potentially leading to shifts in functional pathways with implications for smoking-related diseases. ..
- Diversity of 16S rRNA genes within individual prokaryotic genomesAnna Y Pei
New York University College of Arts and Science, New York, New York 10012, USA
Appl Environ Microbiol 76:3886-97. 2010..This phenomenon is especially seen in 7 bacterial species associated with the human microbiome or diseases...
- A comprehensive evaluation of multicategory classification methods for microbiomic dataAlexander Statnikov
Center for Health Informatics and Bioinformatics, New York University Langone Medical Center, 227 East 30th Street, New York, NY, USA
Microbiome 1:11. 2013..However, it is currently unknown which classifiers perform best among the many available alternatives for classification with microbiomic data...
- HIV-induced immunosuppression is associated with colonization of the proximal gut by environmental bacteriaLiying Yang
aDepartment of Medicine, New York University School of MedicinebThe Department of Veterans Affairs New York Harbor Healthcare SystemcNew York University School of DentistrydDepartment of Pathology, New York University School of Medicine, New York City, New YorkeGene By Gene, Ltd, Houston, Texas, USA
AIDS 30:19-29. 2016..To evaluate the impact of HIV infection on colonization resistance in the proximal gut...
- Microbiome, innate immunity, and esophageal adenocarcinomaJonathan Baghdadi
Department of Medicine, New York University School of Medicine, 550 1st Avenue, New York, NY 10016, USA
Clin Lab Med 34:721-32. 2014..Currently available data are cross-sectional and therefore cannot prove causal relationships. Prospectively, microbiome studies open a new avenue to the understanding of the etiology and pathogenesis of reflux disorders and EAC. ..
- Human papillomavirus community in healthy persons, defined by metagenomics analysis of human microbiome project shotgun sequencing data setsYingfei Ma
New York University, School of Medicine, New York, New York, USA
J Virol 88:4786-97. 2014..This first large-scale survey of HPV using a shotgun sequencing approach yielded a comprehensive map of HPV infections among different body sites of healthy human subjects...
- Leptin and ghrelin in relation to Helicobacter pylori status in adult malesJatin Roper
New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
J Clin Endocrinol Metab 93:2350-7. 2008..Leptin and ghrelin, hormones involved in human energy homeostasis, are both produced in the stomach...
- Oral microbiome profiles: 16S rRNA pyrosequencing and microarray assay comparisonJiyoung Ahn
Division of Epidemiology, Department of Environmental Medicine, New York University School of Medicine, New York, New York, United States of America
PLoS ONE 6:e22788. 2011..We compared two oral microbiome survey methods: broad-based microbiome identification by 16S rRNA gene sequencing and targeted characterization of microbes by custom DNA microarray...
- Case report: Paenibacillus thiaminolyticus: a new cause of human infection, inducing bacteremia in a patient on hemodialysisJie Ouyang
Department of Pathology, State University of New York, Downstate Medical Center, Brooklyn, NY 11209, USA
Ann Clin Lab Sci 38:393-400. 2008..This constitutes the first report of a human infection caused by this organism...
- Fast disease progression in simian HIV-infected female macaque is accompanied by a robust local inflammatory innate immune and microbial responseWuze Ren
aAaron Diamond AIDS Research Center, The Rockefeller University bDepartment of Pathology and Medicine, New York University School of Medicine, New York, New York cPublic Health Research Institute, Rutgers, The State University of New Jersey, New Jersey Medical School, Newark, New Jersey dTulane National Primate Research Center, Tulane University Medical Center, Covington, Louisiana eDepartment of Preventive Medicine and Community Health, Rutgers, The State University of New Jersey, New Jersey Medical School, Newark, New Jersey fDepartment of Veterans Affairs New York Harbour Healthcare System, New York, New York, USA
AIDS 29:F1-8. 2015..Here, we report a novel nonhuman primate model for investigation of sex disparity in HIV disease progression...
- Microbiome in reflux disorders and esophageal adenocarcinomaLiying Yang
From the Department of Medicine, New York University School of Medicine, New York, NY and Department of Veterans Affairs New York Harbor Healthcare System, New York, NY 10010 Departments of Medicine and Pathology, New York University School of Medicine, New York, NY
Cancer J 20:207-10. 2014..However, knowledge of the microbiome in esophageal adenocarcinoma itself is lacking. Microbiome studies open a new avenue to the understanding of the etiology and pathogenesis of reflux disorders. ..
- Radiographic determination of tissue thickness in paraffin blocks: application to the construction of tissue microarraysXiangtian Kong
Department of Pathology, New York University School of Medicine, New York, 10016 NY, USA
Appl Immunohistochem Mol Morphol 15:108-12. 2007..Prior knowledge of tissue thickness in TMA construction can prompt compensatory steps that can enhance the yield of valuable samples and assure sufficient numbers of adequate cores for statistical analysis in biomarker evaluations...
- Androgen receptor coactivator ARA70alpha and ARA70beta isoform-specific antibodies: new tools for studies of expression and immunohistochemical localizationYi Peng
Departments of Pathology, New York University School of Medicine, New York, NY 10010, USA
Appl Immunohistochem Mol Morphol 16:7-12. 2008..ARA70beta localized to the cytosol, whereas ARA70alpha was found in the nucleus, supporting the notion of their dissimilar functions...
- Bacterial community in the crop of the hoatzin, a neotropical folivorous flying birdFilipa Godoy-Vitorino
Department of Biology, University of Puerto Rico, San Juan, Puerto Rico 00931 3360
Appl Environ Microbiol 74:5905-12. 2008..1%). The novelty in this ecosystem is great; 94% of the phylotypes were unclassified at the "species" level and thus likely include novel cellulolytic lineages...
- Molecular analysis of sarcoidosis tissues for mycobacterium species DNAWonder Puryear Drake
Vanderbilt University School of Medicine and Veteran Affairs Medical Center, Nashville, Tennessee 37232, USA
Emerg Infect Dis 8:1334-41. 2002..tuberculosis were negative for IS6110. We provide evidence that one of a variety of Mycobacterium species, especially organisms resembling M. tuberculosis, is found in most patients with sarcoidosis...
- Etiology & pathogenesis of chronic tonsillar hypertrophyZhiheng Pei; Fiscal Year: 2009..Later, we will develop a simple ELISA capable of screening a large number of patients for tonsillar antibodies to the MC-species. Addressing the three aims will provide evidence to examine the hypothesis of a bacterial etiology of CTH. ..
- Bacterial flora in normal esophagus & reflux disordersZhiheng Pei; Fiscal Year: 2005..ii) While GERD initially results from chemical damage, bacterial overgrowth may promote intestinal metaplasia of the esophagus. The proposed study allows qualitative and quantitative examination of this hypothesis. ..