Affiliation: New York Blood Center
- Cloning of a cysteine protease required for the molting of Onchocerca volvulus third stage larvaeS Lustigman
Laboratory of Virology and Parasitology, The Lindsley F Kimball Research Institute, New York Blood Center, New York, New York 10021, USA
J Biol Chem 271:30181-9. 1996..These studies suggest that molting and successful development of L4 depends on the expression and release of a cysteine protease...
- Identification of larval-stage-specific antigens of Onchocerca volvulus uniquely recognized by putative immune sera from humans and vaccination sera from animal modelsM Irvine
Lindsley F Kimball Research Institute, New York Blood Center, NY 10021, USA
Ann Trop Med Parasitol 91:67-77. 1997..The results support the validity of the assumption that a unique status of immunity develops in certain individuals living in areas where onchocerciasis is endemic...
- Caenorhabditis elegans and the study of gene function in parasitesS Hashmi
Laboratory of Molecular Parasitology, Lindsley F. Kimball Research Institute, New York Blood Center, 310 East 67th Street, New York, NY 10021, USA
Trends Parasitol 17:387-93. 2001..elegans genome. Studying such genes using the C. elegans model should yield new insights into key molecules and their possible implications in parasite survival, leading to the discovery of new drug targets and vaccine candidates...
- Ov-ASP-1, the Onchocerca volvulus homologue of the activation associated secreted protein family is immunostimulatory and can induce protective anti-larval immunityA J MacDonald
Laboratory of Molecular Parasitology, Lindsley F Kimball Research Institute, New York Blood Center, New York, NY 10021, USA
Parasite Immunol 26:53-62. 2004..Ov-ASP-1 is potentially secreted based on its localization in the secretory granules of L3...