New York Medical College

Summary

Organization: New York Medical College
Country: USA

Top Publications

  1. doi Mechanisms of oxidant generation by catalase
    Diane E Heck
    Department of Environmental Health Science, School of Health Sciences and Practice, New York Medical College, Valhalla, New York, USA
    Ann N Y Acad Sci 1203:120-5. 2010
  2. ncbi The telomere-telomerase axis and the heart
    Jan Kajstura
    Cardiovascular Research Institute, Department of Medicine, New York Medical College, Valhalla, New York 10595, USA
    Antioxid Redox Signal 8:2125-41. 2006
  3. ncbi In Vivo beta-adrenergic activation of atrial natriuretic factor (ANF) reporter expression
    J G Edwards
    Department of Physiology, New York Medical College, Valhalla, New York, USA
    Mol Cell Biochem 292:119-29. 2006
  4. ncbi Heavy use of prophylactic antibiotics in aquaculture: a growing problem for human and animal health and for the environment
    Felipe C Cabello
    Department of Microbiology and Immunology, New York Medical College, Valhalla, NY 10595, USA
    Environ Microbiol 8:1137-44. 2006
  5. ncbi Estrogen-triggered activation of GTP cyclohydrolase 1 gene expression: role of estrogen receptor subtypes and interaction with cyclic AMP
    L I Serova
    Department of Biochemistry and Molecular Biology, New York Medical College, Valhalla, NY 10595, USA
    Neuroscience 140:1253-63. 2006
  6. ncbi Beta2-adrenoreceptor agonist-enhanced recovery of locomotor function after spinal cord injury is glutathione dependent
    Richard J Zeman
    Department of Cell Biology and Anatomy, New York Medical College, Valhalla, New York 10595, USA
    J Neurotrauma 23:170-80. 2006
  7. ncbi The genetic basis for bronchopulmonary dysplasia
    Lance A Parton
    Division of Neonatology, Department of Pediatrics, New York Medical College, Maria Fareri Children s Hospital, Westchester Medical Center, Valhalla, NY 10595, USA
    Front Biosci 11:1854-60. 2006
  8. ncbi Cerebrovascular events associated with infusion through arterially malpositioned triple-lumen catheter: report of three cases and review of literature
    Pravin M Shah
    Department of Surgery, New York Medical College, Valhalla, NY, USA
    Cardiol Rev 13:304-8. 2005
  9. ncbi Persistent splanchnic hyperemia during upright tilt in postural tachycardia syndrome
    Julian M Stewart
    Department of Pediatrics, New York Medical College, Valhalla, NY, USA
    Am J Physiol Heart Circ Physiol 290:H665-73. 2006
  10. ncbi Risk factors for pancreatic cancer
    Albert B Lowenfels
    Department of Surgery, New York Medical College, Valhalla, New York 10595, USA
    J Cell Biochem 95:649-56. 2005

Research Grants

  1. Circulatory Dysfunction in Chronic Fatigue Syndrome
    Julian Stewart; Fiscal Year: 2004
  2. Detecting Endothelial Dysfunction in Renal Failure
    Julian Stewart; Fiscal Year: 2007
  3. Vascular Dysfunction in CFS
    Julian M Stewart; Fiscal Year: 2010
  4. Local Vasoconstriction in Postural Tachycardia Syndrome
    Julian M Stewart; Fiscal Year: 2010
  5. Local Vasoconstriction in Postural Tachycardia Syndrome
    Julian Stewart; Fiscal Year: 2007
  6. Topical Antibiotics to Prevent Lyme Disease
    Gary Wormser; Fiscal Year: 2007
  7. Subjective Symptoms after Treatment of Lyme Disease
    Gary P Wormser; Fiscal Year: 2010
  8. Oxidative Stress and Vascular HO in Diabetes
    Nader Abraham; Fiscal Year: 2007
  9. PROBES FOR CYTOMETRY
    Zbigniew Darzynkiewicz; Fiscal Year: 2010
  10. PROBES FOR CYTOMETRY
    Zbigniew Darzynkiewicz; Fiscal Year: 2009

Detail Information

Publications62

  1. doi Mechanisms of oxidant generation by catalase
    Diane E Heck
    Department of Environmental Health Science, School of Health Sciences and Practice, New York Medical College, Valhalla, New York, USA
    Ann N Y Acad Sci 1203:120-5. 2010
    ..Conformational changes following absorption of UVB light by catalase NADPH have the potential to facilitate ROS production by the enzyme...
  2. ncbi The telomere-telomerase axis and the heart
    Jan Kajstura
    Cardiovascular Research Institute, Department of Medicine, New York Medical College, Valhalla, New York 10595, USA
    Antioxid Redox Signal 8:2125-41. 2006
    ....
  3. ncbi In Vivo beta-adrenergic activation of atrial natriuretic factor (ANF) reporter expression
    J G Edwards
    Department of Physiology, New York Medical College, Valhalla, New York, USA
    Mol Cell Biochem 292:119-29. 2006
    ....
  4. ncbi Heavy use of prophylactic antibiotics in aquaculture: a growing problem for human and animal health and for the environment
    Felipe C Cabello
    Department of Microbiology and Immunology, New York Medical College, Valhalla, NY 10595, USA
    Environ Microbiol 8:1137-44. 2006
    ....
  5. ncbi Estrogen-triggered activation of GTP cyclohydrolase 1 gene expression: role of estrogen receptor subtypes and interaction with cyclic AMP
    L I Serova
    Department of Biochemistry and Molecular Biology, New York Medical College, Valhalla, NY 10595, USA
    Neuroscience 140:1253-63. 2006
    ....
  6. ncbi Beta2-adrenoreceptor agonist-enhanced recovery of locomotor function after spinal cord injury is glutathione dependent
    Richard J Zeman
    Department of Cell Biology and Anatomy, New York Medical College, Valhalla, New York 10595, USA
    J Neurotrauma 23:170-80. 2006
    ....
  7. ncbi The genetic basis for bronchopulmonary dysplasia
    Lance A Parton
    Division of Neonatology, Department of Pediatrics, New York Medical College, Maria Fareri Children s Hospital, Westchester Medical Center, Valhalla, NY 10595, USA
    Front Biosci 11:1854-60. 2006
    ....
  8. ncbi Cerebrovascular events associated with infusion through arterially malpositioned triple-lumen catheter: report of three cases and review of literature
    Pravin M Shah
    Department of Surgery, New York Medical College, Valhalla, NY, USA
    Cardiol Rev 13:304-8. 2005
    ..Infusion by volumetric pump precludes backflow of blood in the intravenous tubing as an indicator. Neurologic symptoms concurrent with the infusion of fluids and medication should raise suspicion of accidental arterial infusion...
  9. ncbi Persistent splanchnic hyperemia during upright tilt in postural tachycardia syndrome
    Julian M Stewart
    Department of Pediatrics, New York Medical College, Valhalla, NY, USA
    Am J Physiol Heart Circ Physiol 290:H665-73. 2006
    ..Lower body vasoconstriction in high-flow POTS was abnormal, and vasoconstriction in low-flow POTS was sustained at initially elevated supine levels...
  10. ncbi Risk factors for pancreatic cancer
    Albert B Lowenfels
    Department of Surgery, New York Medical College, Valhalla, New York 10595, USA
    J Cell Biochem 95:649-56. 2005
    ..Major challenges presented by this cancer are: 1) determination of the molecular pathways that make this cancer so aggressive; 2) development of new modalities, perhaps based on proteomics, to enhance early detection...
  11. pmc Microbiologic evaluation of patients from Missouri with erythema migrans
    Gary P Wormser
    Division of Infectious Diseases, Department of Medicine, New York Medical College, Valhalla, NY 10595, USA
    Clin Infect Dis 40:423-8. 2005
    ..Therefore, B. lonestari is considered to be a leading candidate for the etiologic agent of EM in this region...
  12. ncbi Thresholds for the effects of 2-acetylaminofluorene in rat liver
    Gary M Williams
    New York Medical College, Department of Pathology, Valhalla, New York 10595, USA
    Toxicol Pathol 32:85-91. 2004
    ..Thus, mechanisms of carcinogenesis can differ between low and high doses...
  13. ncbi Overexpression of human heme oxygenase-1 attenuates endothelial cell sloughing in experimental diabetes
    Nader G Abraham
    Department of Pharmacology, New York Medical College, Valhalla, NY 10595, USA
    Am J Physiol Heart Circ Physiol 287:H2468-77. 2004
    ..Upregulation of HO-1 decreases oxidant production and endothelial cell damage and shedding and may attenuate vascular complications in diabetes...
  14. ncbi Dietary K intake regulates the response of apical K channels to adenosine in the thick ascending limb
    Dimin Li
    Dept of Pharmacology, BSB Rm 537, New York Medical College, Valhalla, NY 10595, USA
    Am J Physiol Renal Physiol 287:F954-9. 2004
    ..Moreover, the diminished response to adenosine is the result of increase in 20-HETE formation, which inhibits the cAMP-dependent pathway in the TAL from rats on a KD diet...
  15. ncbi Promethean medicine: spirituality, stem cells, and cloning
    Daniel P Sulmasy
    John J Conley Department of Ethics, St Vincent s Hospital, Manhattan, NY 10011, USA
    South Med J 99:1419-23. 2006
    ..The illusory quest for immortality through the practice of regenerative medicine using stem cells is a gross violation of that virtue...
  16. ncbi Exploring DNA topoisomerases as targets of novel therapeutic agents in the treatment of infectious diseases
    Y C Tse-Dinh
    Department of Biochemistry and Molecular Biology, New York Medical College, Valhalla, NY 10595, USA
    Infect Disord Drug Targets 7:3-9. 2007
    ..These new developments of DNA topoisomerases as targets of novel therapeutic agents being reviewed here represent excellent opportunities for drug discovery in the treatment of infectious diseases...
  17. ncbi Diagnostic potential of urine proteome: a broken mirror of renal diseases
    Michael S Goligorsky
    Department of Medicine, New York Medical College, Valhalla, NY 10595, USA
    J Am Soc Nephrol 18:2233-9. 2007
    ..The future chance that the centuries-old technique of uroscopy will reveal its secrets using modern proteomic approaches makes gradual improvement...
  18. doi Inflammation and pulmonary hypertension
    Rajamma Mathew
    Section of Pediatric Cardiology, Maria Fareri Children s Hospital, New York Medical College, Valhalla, NY 10595, USA
    Cardiol Rev 18:67-72. 2010
    ..This article summarizes the roles of inflammation and endothelial caveolin-1 and their possible interrelationship in PH...
  19. doi An evaluation of colonoscopy use: implications for health education
    Chia Ching Chen
    Department of Epidemiology and Community Health, School of Health Sciences and Practice, New York Medical College, 95 Grasslands Road, Valhalla, NY 10595, USA
    J Cancer Educ 25:160-5. 2010
    ..The findings indicate a continuous effort to increase awareness and risk perception, and reduce psychological barriers through health education...
  20. pmc Identification of the putative tumor suppressor Nit2 as omega-amidase, an enzyme metabolically linked to glutamine and asparagine transamination
    Boris F Krasnikov
    Department of Biochemistry and Molecular Biology, New York Medical College, Valhalla, NY 10595, USA
    Biochimie 91:1072-80. 2009
    ....
  21. pmc Phase 1 trial of 4 thyroid hormone regimens for transient hypothyroxinemia in neonates of <28 weeks' gestation
    Edmund F La Gamma
    Department of Neonatal Perinatal Medicine, Regional Neonatal Center, Maria Fareri Children s Hospital at Westchester Medical Center, New York Medical College, Valhalla, New York 10595, USA
    Pediatrics 124:e258-68. 2009
    ..Raising hormone levels shows promise for improving neurodevelopmental outcome...
  22. doi Patterns, art, and context: Donald Floyd Gleason and the development of the Gleason grading system
    John L Phillips
    Department of Urology, New York Medical College, Hawthorne, NY 10595, USA
    Urology 74:497-503. 2009
    ..Donald F. Gleason recognized trends in histologic patterns which had eluded earlier, more sophisticated pathologic approaches and which lie as the basis for the sophisticated neural networks and nomograms in use today...
  23. pmc Defects in cutaneous angiotensin-converting enzyme 2 and angiotensin-(1-7) production in postural tachycardia syndrome
    Julian M Stewart
    The Center for Pediatric Hypotension, Suite 1600 S, 19 Bradhurst Ave, New York Medical College, Hawthorne, NY 10532, USA
    Hypertension 53:767-74. 2009
    ..Data imply impaired catabolism of Ang II through the ACE2 pathway. Vasoconstriction in POTS may result from a reduction in Ang-(1-7) and an increase in Ang II...
  24. pmc Bacterial topoisomerase I as a target for discovery of antibacterial compounds
    Yuk Ching Tse-Dinh
    Department of Biochemistry and Molecular Biology, New York Medical College, Valhalla, NY 10595, USA
    Nucleic Acids Res 37:731-7. 2009
    ..Topoisomerase I targeting poisons may be particularly effective when the bacterial pathogen is responding to host defense, or in the presence of other antibiotics that induce the bacterial stress response...
  25. doi Stereotactic radiosurgery improves locomotor recovery after spinal cord injury in rats
    Richard J Zeman
    Department of Cell Biology and Anatomy, New York Medical College, Valhalla, New York 10595, USA
    Neurosurgery 63:981-7; discussion 987-8. 2008
    ....
  26. ncbi Biliary dyskinesia in the pediatric patient
    Michael S Halata
    Department of Pediatric Gastroenterology, Maria Fareri Children s Hospital, New York Medical College, Munger Pavilion, Room 101, Valhalla, NY 10595, USA
    Curr Gastroenterol Rep 10:332-8. 2008
    ..GBD and SOD are uncommon in children. Based on adult experience, this review discusses the diagnosis and treatment of GBD and SOD in the pediatric population...
  27. doi Bone marrow stem cell transplant into intra-bone cavity prevents type 2 diabetes: role of heme oxygenase-adiponectin
    Nader G Abraham
    Department of Pharmacology, New York Medical College, Valhalla, NY 10595, USA
    J Autoimmun 30:128-35. 2008
    ..Thus, transplantation of BMSC using the IBM-BMT strategy in conjunction with HO-1 induction offers a novel approach for the treatment of type 2 diabetes...
  28. ncbi Pathophysiology, diagnosis, and treatment of orthostatic hypotension and vasovagal syncope
    Marvin S Medow
    Department of Pediatrics, New York Medical College, Valhalla, New York 10595, USA
    Cardiol Rev 16:4-20. 2008
    ..Treatment for recurrent vasovagal syncope includes increased salt and water intake and various drug treatments, most of which are still under investigation...
  29. ncbi Spinal Kaposi sarcoma presenting without cutaneous manifestations. Case report
    Ibrahim Omeis
    Department of Neurosurgery, New York Medical College and St Vincent s Medical Center, Valhalla 10595, USA
    J Neurosurg Spine 7:558-61. 2007
    ..The authors suggest that in HIV-positive patients who present with spinal lesions, KS should be included in the differential diagnosis...
  30. ncbi Reinfection in patients with Lyme disease
    Robert B Nadelman
    Division of Infectious Diseases, Department of Medicine, New York Medical College, Valhalla, NY 10595, USA
    Clin Infect Dis 45:1032-8. 2007
    ..Because patients with early Lyme disease continue to remain at high risk for reinfection, this population should be targeted for education about prevention of Lyme disease...
  31. ncbi Gemcitabine and vinorelbine as a salvage regimen for relapse in Hodgkin lymphoma after autologous hematopoietic stem cell transplantation
    M Fevzi Ozkaynak
    New York Medical College, Department of Pediatrics, Section of Hematology Oncology, Valhalla, NY 10595, USA
    Pediatr Hematol Oncol 21:107-13. 2004
    ..This novel and promising combination needs to be studied in a larger number of relapsed Hodgkin disease patients...
  32. ncbi Nitric oxide synthesis inhibition promotes renal production of carbon monoxide
    Francisca Rodriguez
    Department of Pharmacology, New York Medical College, Valhalla, NY 10595, USA
    Hypertension 43:347-51. 2004
    ..Our findings imply that endogenous NO is an inhibitory regulator of renal CO generation by HO...
  33. ncbi Can simvastatin promote tumor growth by inducing angiogenesis similar to VEGF?
    Z Ungvari
    Department of Pathophysiology, Semmelweis University, Budapest, Hungary
    Med Hypotheses 58:85-6. 2002
    ..Thus, it can be hypothesized that chronic systemic treatment of elderly patients with a drug that induces angiogenesis by a VEGF-like manner will also promote tumor growth...
  34. ncbi Myocyte growth and cardiac repair
    Piero Anversa
    Cardiovascular Research Institute, Department of Medicine, Valhalla, New York 10595, USA
    J Mol Cell Cardiol 34:91-105. 2002
    ..Methodologies are currently available to recognize and measure quantitatively the contribution of myocyte size, number and death to the adaptation of the overloaded heart and its progression to cardiac failure...
  35. ncbi Use of flow and laser scanning cytometry to study mechanisms regulating cell cycle and controlling cell death
    Z Darzynkiewicz
    Brander Cancer Research Institute, New York Medical College, Valhalla, New York, USA
    Clin Lab Med 21:857-73. 2001
    ..One of the dominating motors for this progress will be further development of cytometry instrumentation and the applicability of this instrumentation, methods, and probes...
  36. ncbi Increased vascular compliance/decreased cardiovascular risk: what the studies tell us
    W H Frishman
    Department of Medicine, Munger Pavilion, Room 263, New York Medical College and Westchester Medical Center, Valhalla, NY 10595, USA
    Heart Dis 2:384-8. 2000
    ..ACE inhibitors restore endothelial cell balance to improve arterial compliance, thus they can provide benefits beyond lowering blood pressure...
  37. ncbi Giant petrous carotid aneurysm treated by submandibular carotid-saphenous vein bypass. Case report
    W T Couldwell
    Department of Neurological Surgery, New York Medical College, Valhalla 10595, USA
    J Neurosurg 94:806-10. 2001
    ..The presentation and technical aspects of the bypass graft in this unique case are discussed...
  38. ncbi Effect of intact and isoflavone-depleted soy protein on NMU-induced rat mammary tumorigenesis
    L A Cohen
    American Health Foundation, 1 Dana Road, Valhalla, NY 20595 and Kraft Foods Inc, Glenview, IL 60025, USA
    Carcinogenesis 21:929-35. 2000
    ..The results of this model study do not support the hypothesis that the isoflavone components of soy protein, or soy protein itself, inhibit chemically induced mammary tumor development...
  39. ncbi Clenbuterol reduces degeneration of exercised or aged dystrophic (mdx) muscle
    R J Zeman
    Department of Cell Biology and Anatomy, New York Medical College, Valhalla, New York 10595, USA
    Muscle Nerve 23:521-8. 2000
    ..Optimization of beta(2)-agonist treatment of muscular dystrophy in mdx mice may lead to a useful therapeutic modality for human forms of the disease...
  40. ncbi Carcinogenicity and mutagenicity testing, then and now
    J H Weisburger
    American Health Foundation, 1 Dana Road, Valhalla, NY, USA
    Mutat Res 437:105-12. 1999
    ..Thus, batteries of tests are now available to detect effectively human cancer risks, and provide novel approaches to determine the underlying mechanisms, as a sound basis for cancer prevention...
  41. pmc Renal cytochrome P450 omega-hydroxylase and epoxygenase activity are differentially modified by nitric oxide and sodium chloride
    A O Oyekan
    Department of Pharmacology, New York Medical College, Valhalla, New York 10595, USA
    J Clin Invest 104:1131-7. 1999
    ..Thus, inhibition of NOS increased omega-hydroxylase activity, CYP4A expression, and renal efflux of 20-HETE, whereas 2% NaCl stimulated epoxygenase activity...
  42. ncbi Pancreatico-biliary malignancy: prevalence and risk factors
    A B Lowenfels
    Department of Surgery, New York Medical College, Valhalla, USA
    Ann Oncol 10:1-3. 1999
    ..For pancreatic cancer, public health efforts to reduce smoking offers the best chance for prevention...
  43. ncbi Expression of actin mRNA in embryos of the leech Helobdella triserialis
    C J Wedeen
    Department of Cell Biology and Anatomy, New York Medical College, Valhalla 10595, USA
    Int J Dev Biol 42:581-90. 1998
    ..The Htr-actin transcript was undetectable in the segmental nervous system. These studies lay the groundwork for any future ectopic gene expression studies using the Htr-actin promoter in the leech embryo...
  44. ncbi Tea, or tea and milk, inhibit mammary gland and colon carcinogenesis in rats
    J H Weisburger
    American Health Foundation, Valhalla, NY 10595 1599, USA
    Cancer Lett 114:323-7. 1997
    ..Thus, tea decreases mammary tumor induction, and the production of foci of aberrant crypts in the colon. Milk potentiates these inhibiting effects...
  45. ncbi Sticky fingers: Hox genes and cell adhesion in vertebrate limb development
    S A Newman
    Department of Cell Biology and Anatomy, New York Medical College, Valhalla 10595, USA
    Bioessays 18:171-4. 1996
    ..They misexpressed the product of the Hoxa-13 gene in chick limb buds and demonstrated both skeletal pattern perturbations and changes in cell-cell adhesivity in mesenchyme aberrantly expressing this protein...
  46. ncbi Metformin and carbohydrate-modified diet: a novel obesity treatment protocol: preliminary findings from a case series of nondiabetic women with midlife weight gain and hyperinsulinemia
    H R Mogul
    Division of Endocrinology, New York Medical College, Valhalla, New York, USA
    Heart Dis 3:285-92. 2001
    ..The authors concluded that metformin and carbohydrate-modified hypocaloric diet could be an effective novel treatment for long-term weight management in nondiabetic, hyperinsulinemic women...
  47. ncbi Subthalamic nucleus stimulation in patients with a prior pallidotomy
    Alon Y Mogilner
    Department of Neurosurgery, New York University School of Medicine, New York, USA
    J Neurosurg 96:660-5. 2002
    ..Potential alterations in physiological features of the STN after pallidotomy may complicate localization of this structure in this group of patients...
  48. ncbi Impaired regulation of renal oxygen consumption in spontaneously hypertensive rats
    Stephen Adler
    Department of Medicine, Division of Nephrology, New York Medical College, 19 Bradhurst Avenue, Suite 0100, Hawthorne, NY 10532, USA
    J Am Soc Nephrol 13:1788-94. 2002
    ..By lowering intrarenal oxygen levels, reduced NO may contribute to susceptibility to injury and renal fibrosis. Increasing NO production, decreasing oxidant stress, or both might prevent these changes by improving renal oxygenation...
  49. ncbi Oxidant stress leads to impaired regulation of renal cortical oxygen consumption by nitric oxide in the aging kidney
    Stephen Adler
    Division of Nephrology, Department of Medicine, New York Medical College, Valhalla, New York, USA
    J Am Soc Nephrol 15:52-60. 2004
    ..Oxidant stress, by depleting NO, may contribute to the structural and hemodynamic changes characteristic of the aging kidney...
  50. ncbi Sources of exposure to and public health implications of organophosphate pesticides
    Kushik Jaga
    VA Hudson Valley Healthcare System, Montrose Research Corporation, Montrose, New York 10523, USA
    Rev Panam Salud Publica 14:171-85. 2003
    ..Looking at the situation in the United States would serve to further emphasize the seriousness of organophosphate pesticide-related health issues in developing countries...
  51. ncbi Abusive head injury as a cause of apparent life-threatening events in infancy
    Robin L Altman
    Department of Pediatrics, Westchester Medical Center, Valhalla, USA
    Arch Pediatr Adolesc Med 157:1011-5. 2003
    ..Several patients with ALTEs admitted to our institution were found to have sustained abusive head injuries...
  52. pmc Tissue-selective therapy of cancer
    M V Blagosklonny
    Department of Medicine, New York Medical College, Valhalla, NY 10595, USA
    Br J Cancer 89:1147-51. 2003
    ..Despite inherent limitations, such as fostering resistance and dedifferentiation, tissue-selective therapy have enormous potentials to control cancer...
  53. pmc Helicases as antiviral drug targets
    David N Frick
    Biochemistry and Molecular Biology, New York Medical College, Valhalla, NY 10595, USA
    Drug News Perspect 16:355-62. 2003
    ..These new developments should eventually lead to new antiviral medications...
  54. ncbi Local vascular responses affecting blood flow in postural tachycardia syndrome
    Julian M Stewart
    Department of Pediatrics, Center for Pediatric Hypotension and Division of Pediatric Cardiology, Suite 618, Munger Pavilion, New York Medical College, Valhalla, NY 10595, USA
    Am J Physiol Heart Circ Physiol 285:H2749-56. 2003
    ..29 +/- 4 and 28 +/- 4 s; cutaneous time constant = 60 +/- 25 vs. 149 +/- 53 s in controls). Local blood flow regulation in low-flow POTS is impaired...
  55. ncbi Targeting cancer cells by exploiting their resistance
    Mikhail V Blagosklonny
    Brander Cancer Research Institute, New York Medical College, 19 Bradhurst Ave, Hawthorne, NY 10532, USA
    Trends Mol Med 9:307-12. 2003
    ..By abolishing several dose-limiting side effects of chemotherapy, this strategy provides a means to treat selectively most deranged, aggressive and resistant cancers...
  56. ncbi Laboratory aspects of tick-borne diseases: lyme, human granulocytic ehrlichiosis and babesiosis
    Marie E Aguero-Rosenfeld
    Clinical Laboratories, Room 1J 11a, Westchester Medical Center, Valhalla, NY 10595, USA
    Mt Sinai J Med 70:197-206. 2003
    ..Co-infections with these agents exist, but they should be documented by detection of the organisms rather than by serology, since seroprevalence rates are high in endemic areas...
  57. ncbi Use of vincristine and cyclosporine in childhood thrombotic thrombocytopenic purpura
    Somasundaram Jayabose
    New York Medical College, Valhalla 10595, USA
    J Pediatr Hematol Oncol 25:421-5. 2003
    ..The authors' experience in this case study of three patients suggests that vincristine and cyclosporine are effective agents in the management of patients with TTP who do not achieve complete remission with plasmapheresis alone...
  58. ncbi The eicosanoid factor: a determinant of individuality of nephron segments
    J C McGiff
    Dept Pharmacology, New York Medical College, Valhalla, NY 10595, USA
    J Physiol Pharmacol 53:525-32. 2002
    ..The overriding importance of the mTAL to regulation of ECFV is evident in the diuretic-natriuretic potency of furosemide-like agents which target the mTAL...
  59. ncbi Are antihypertensive agents protective against dementia? A review of clinical and preclinical data
    William H Frishman
    Department of Medicine, New York Medical College, Westchester Medical Center, Valhalla, New York 10595, USA
    Heart Dis 4:380-6. 2002
    ..In animal models, these newer agents also have been shown to prevent the progression of hypertensive microvascular damage. Their neuroprotective effects offer possible unique advantages in the management of hypertension...
  60. ncbi Visual spatial perception and surgical competence
    Donald A Risucci
    Department of Surgery, New York Medical College, Munger Pavilion, Valhalla, NY 10595, USA
    Am J Surg 184:291-5. 2002
    ..Proficiency in visual spatial perception (VSP) is a hypothetical component of surgical competence...
  61. ncbi Beyond the role of glutamate as a neurotransmitter
    Maiken Nedergaard
    Department of Cell Biology and Anatomy, New York Medical College, Valhalla, New York 10595, USA
    Nat Rev Neurosci 3:748-55. 2002
    ..Here, we review the current knowledge on glutamatergic signalling in non-neuronal cells, with a special emphasis on astrocytes...
  62. ncbi Blood glutathione concentrations in a large-scale human study
    J P Richie
    Division of Nutrional Carcinogenesis, American Health Foundation, Valhalla, NY 10595, USA
    Clin Chem 42:64-70. 1996
    ..05). The results presented here validate the use of this method for large-scale human studies and provide information on the variation and normal values of blood GSH in adults...

Research Grants62

  1. Circulatory Dysfunction in Chronic Fatigue Syndrome
    Julian Stewart; Fiscal Year: 2004
    ....
  2. Detecting Endothelial Dysfunction in Renal Failure
    Julian Stewart; Fiscal Year: 2007
    ..These data will form the basis of future noninvasive prognostic testing and treatment of patients at risk for ECD and can provide a means to follow treatment modalities. ..
  3. Vascular Dysfunction in CFS
    Julian M Stewart; Fiscal Year: 2010
    ..These may be due to defects in a fundamental signaling molecule called nitric oxide (NO). In the current application we will determine how NO produces POTS in CFS patients and whether drugs that alter NO can improve patient health. ..
  4. Local Vasoconstriction in Postural Tachycardia Syndrome
    Julian M Stewart; Fiscal Year: 2010
    ..In the current proposal we will perform sophisticated tests of the circulation and nervous systems to study the causes and mechanisms in these patients and we will test drug treatments. ..
  5. Local Vasoconstriction in Postural Tachycardia Syndrome
    Julian Stewart; Fiscal Year: 2007
    ..Verifying these hypotheses will improve our ability to diagnose and treat an important cause of vascular pathophysiology in man. ..
  6. Topical Antibiotics to Prevent Lyme Disease
    Gary Wormser; Fiscal Year: 2007
    ....
  7. Subjective Symptoms after Treatment of Lyme Disease
    Gary P Wormser; Fiscal Year: 2010
    ..In a different group of patients, we will describe for the first time the outcome of patients with early Lyme disease more than 10 years after diagnosis and treatment. ..
  8. Oxidative Stress and Vascular HO in Diabetes
    Nader Abraham; Fiscal Year: 2007
    ..It will allow for the first time, an in-depth analysis of the function of HO-1 in vascular protection and for the development of innovative gene-targeting therapies for the treatment of type I diabetes. ..
  9. PROBES FOR CYTOMETRY
    Zbigniew Darzynkiewicz; Fiscal Year: 2010
    ....
  10. PROBES FOR CYTOMETRY
    Zbigniew Darzynkiewicz; Fiscal Year: 2009
    ..abstract_text> ..
  11. Oxidative Stress and Vascular HO in Diabetes
    Nader Abraham; Fiscal Year: 2009
    ..It will allow for the first time, an in-depth analysis of the function of HO-1 in vascular protection and for the development of innovative gene-targeting therapies for the treatment of type I diabetes. ..
  12. PROBES FOR FLOW CYTOMETRY
    Zbigniew Darzynkiewicz; Fiscal Year: 1993
    ..This in turn will help assess the cellular features predicting susceptibility to particular drugs and aid in new drug design...
  13. PROBES FOR FLOW CYTOMETRY
    Zbigniew Darzynkiewicz; Fiscal Year: 1999
    ..it is expected that such a combined analysis, especially involving estimates of the G1 and G2 cyclins, will be of high prognostic value, and will be used during treatment, to monitor tumor response. ..
  14. Weibel - Palade Bodies - Sentinels of Acute Ischemia
    MICHAEL GOLIGORSKY; Fiscal Year: 2009
    ....
  15. Weibel - Palade Bodies - Sentinels of Acute Ischemia
    Michael S Goligorsky; Fiscal Year: 2010
    ....
  16. ENDOTHELIAL DYSFUNCTION, NITRIC OXIDE AND RENAL FAILURE
    MICHAEL GOLIGORSKY; Fiscal Year: 2007
    ....
  17. Endothelial dysfunction in acute renal ischemia
    MICHAEL GOLIGORSKY; Fiscal Year: 2007
    ..Number of publicationsand manuscriptsacceptedfor publication (not to exceed 10) 10 Other items (list): 1. Color illustrations from the grant application 2. Movies - intravital videomicroscopy supplement ..
  18. Endothelial dysfunction in acute renal ischemia
    MICHAEL GOLIGORSKY; Fiscal Year: 2006
    ..It is anticipated that novel therapeutic strategies should be disclosed, which could be applicable to prevention of acute renal failure. ..