Alistair Harrison

Summary

Affiliation: Nationwide Children's Hospital
Country: USA

Publications

  1. pmc Overlapping and complementary oxidative stress defense mechanisms in nontypeable Haemophilus influenzae
    Alistair Harrison
    The Center for Microbial Pathogenesis at the Research Institute at Nationwide Children s Hospital and the Center for Microbial Interface Biology and Department of Pediatrics, The Ohio State University, Ohio, USA
    J Bacteriol 197:277-85. 2015
  2. pmc Ferric uptake regulator and its role in the pathogenesis of nontypeable Haemophilus influenzae
    Alistair Harrison
    The Center for Microbial Pathogenesis, The Research Institute at Nationwide Children s Hospital, The Center for Microbial Interface Biology, and Department of Pediatrics, The Ohio State University, Columbus, Ohio, USA
    Infect Immun 81:1221-33. 2013
  3. pmc The OxyR regulon in nontypeable Haemophilus influenzae
    Alistair Harrison
    Columbus Children s Research Institute, Center for Microbial Pathogenesis, The Ohio State University College of Medicine and Public Health, 700 Children s Drive, Columbus, OH 43205 2696, USA
    J Bacteriol 189:1004-12. 2007
  4. pmc Genomic sequence of an otitis media isolate of nontypeable Haemophilus influenzae: comparative study with H. influenzae serotype d, strain KW20
    Alistair Harrison
    Center for Microbial Pathogenesis, Columbus Children s Research Institute, Ohio State University College of Medicine and Public Health, Columbus, Ohio 43205, USA
    J Bacteriol 187:4627-36. 2005
  5. pmc Demonstration of Type IV pilus expression and a twitching phenotype by Haemophilus influenzae
    Lauren O Bakaletz
    Department of Pediatrics, Columbus Children s Research Institute, Center for Microbial Pathogenesis, The Ohio State University College of Medicine and Public Health, 700 Children s Dr, Columbus, OH 43205 2696, USA
    Infect Immun 73:1635-43. 2005
  6. pmc Comprehensive Proteomic and Metabolomic Signatures of Nontypeable Haemophilus influenzae-Induced Acute Otitis Media Reveal Bacterial Aerobic Respiration in an Immunosuppressed Environment
    Alistair Harrison
    From the The Center for Microbial Pathogenesis, The Research Institute at Nationwide Children s Hospital, Columbus, Ohio 43205
    Mol Cell Proteomics 15:1117-38. 2016
  7. pmc Haemophilus influenzae and oxidative stress
    Alistair Harrison
    The Center for Microbial Pathogenesis, The Research Institute at Nationwide Children s Hospital, Columbus OH, USA alistair harrison nationwidechildrens org
    Front Cell Infect Microbiol 2:40. 2012
  8. pmc HrrF is the Fur-regulated small RNA in nontypeable Haemophilus influenzae
    Estevan A Santana
    The Center for Microbial Pathogenesis, The Research Institute at Nationwide Children s Hospital, Columbus, Ohio, United States of America The Center for Microbial Interface Biology, The Ohio State University, Columbus, Ohio, United States of America Department of Pediatrics, The Ohio State University, Columbus, Ohio, United States of America
    PLoS ONE 9:e105644. 2014
  9. pmc Partial analysis of the genomes of two nontypeable Haemophilus influenzae otitis media isolates
    Robert S Munson
    Center for Microbial Pathogenesis, Columbus Children s Research Institute and The Department of Pediatrics, The Ohio State University, Columbus, Ohio 43205, USA
    Infect Immun 72:3002-10. 2004
  10. pmc Silver nanoparticles embedded in zeolite membranes: release of silver ions and mechanism of antibacterial action
    Amber Nagy
    Department of Pathology, The Ohio State University, Columbus, OH, USA
    Int J Nanomedicine 6:1833-52. 2011

Collaborators

Detail Information

Publications12

  1. pmc Overlapping and complementary oxidative stress defense mechanisms in nontypeable Haemophilus influenzae
    Alistair Harrison
    The Center for Microbial Pathogenesis at the Research Institute at Nationwide Children s Hospital and the Center for Microbial Interface Biology and Department of Pediatrics, The Ohio State University, Ohio, USA
    J Bacteriol 197:277-85. 2015
    ..These mechanisms will be important for successful colonization and infection by this opportunistic human pathogen. ..
  2. pmc Ferric uptake regulator and its role in the pathogenesis of nontypeable Haemophilus influenzae
    Alistair Harrison
    The Center for Microbial Pathogenesis, The Research Institute at Nationwide Children s Hospital, The Center for Microbial Interface Biology, and Department of Pediatrics, The Ohio State University, Columbus, Ohio, USA
    Infect Immun 81:1221-33. 2013
    ..Identification of such pathways will increase our understanding of how this pathogen can persist within host microenvironments, as a common commensal and, importantly, as a pathogen with significant clinical impact...
  3. pmc The OxyR regulon in nontypeable Haemophilus influenzae
    Alistair Harrison
    Columbus Children s Research Institute, Center for Microbial Pathogenesis, The Ohio State University College of Medicine and Public Health, 700 Children s Drive, Columbus, OH 43205 2696, USA
    J Bacteriol 189:1004-12. 2007
    ....
  4. pmc Genomic sequence of an otitis media isolate of nontypeable Haemophilus influenzae: comparative study with H. influenzae serotype d, strain KW20
    Alistair Harrison
    Center for Microbial Pathogenesis, Columbus Children s Research Institute, Ohio State University College of Medicine and Public Health, Columbus, Ohio 43205, USA
    J Bacteriol 187:4627-36. 2005
    ..These data provide new insight that complements and extends the ongoing analysis of nontypeable H. influenzae virulence determinants...
  5. pmc Demonstration of Type IV pilus expression and a twitching phenotype by Haemophilus influenzae
    Lauren O Bakaletz
    Department of Pediatrics, Columbus Children s Research Institute, Center for Microbial Pathogenesis, The Ohio State University College of Medicine and Public Health, 700 Children s Dr, Columbus, OH 43205 2696, USA
    Infect Immun 73:1635-43. 2005
    ..The recognition that H. influenzae possesses a mechanism for twitching motility will likely profoundly influence our understanding of H. influenzae-induced diseases of the respiratory tract and their sequelae...
  6. pmc Comprehensive Proteomic and Metabolomic Signatures of Nontypeable Haemophilus influenzae-Induced Acute Otitis Media Reveal Bacterial Aerobic Respiration in an Immunosuppressed Environment
    Alistair Harrison
    From the The Center for Microbial Pathogenesis, The Research Institute at Nationwide Children s Hospital, Columbus, Ohio 43205
    Mol Cell Proteomics 15:1117-38. 2016
    ..Identification of novel protein targets and metabolic biomarkers will advance development of therapeutic and diagnostic options for treatment of disease. ..
  7. pmc Haemophilus influenzae and oxidative stress
    Alistair Harrison
    The Center for Microbial Pathogenesis, The Research Institute at Nationwide Children s Hospital, Columbus OH, USA alistair harrison nationwidechildrens org
    Front Cell Infect Microbiol 2:40. 2012
    ..Moreover, we will compare how H. influenzae combats the effect of oxidative stress as a necessary phenotype for its roles as both a successful commensal and pathogen...
  8. pmc HrrF is the Fur-regulated small RNA in nontypeable Haemophilus influenzae
    Estevan A Santana
    The Center for Microbial Pathogenesis, The Research Institute at Nationwide Children s Hospital, Columbus, Ohio, United States of America The Center for Microbial Interface Biology, The Ohio State University, Columbus, Ohio, United States of America Department of Pediatrics, The Ohio State University, Columbus, Ohio, United States of America
    PLoS ONE 9:e105644. 2014
    ..The stability of HrrF is not dependent on the RNA chaperone Hfq. This study is the first step in an effort to investigate the role small RNAs play in altering gene expression in response to iron limitation in NTHi. ..
  9. pmc Partial analysis of the genomes of two nontypeable Haemophilus influenzae otitis media isolates
    Robert S Munson
    Center for Microbial Pathogenesis, Columbus Children s Research Institute and The Department of Pediatrics, The Ohio State University, Columbus, Ohio 43205, USA
    Infect Immun 72:3002-10. 2004
    ..We also identified a number of putative restriction-modification systems, bacteriophage genes and transposon-related genes. These data provide new insight that complements and extends our ongoing analysis of NTHI virulence determinants...
  10. pmc Silver nanoparticles embedded in zeolite membranes: release of silver ions and mechanism of antibacterial action
    Amber Nagy
    Department of Pathology, The Ohio State University, Columbus, OH, USA
    Int J Nanomedicine 6:1833-52. 2011
    ..The focus of this study is on the antibacterial properties of silver nanoparticles embedded within a zeolite membrane (AgNP-ZM)...
  11. pmc KatG and KatE confer Acinetobacter resistance to hydrogen peroxide but sensitize bacteria to killing by phagocytic respiratory burst
    Daqing Sun
    Center for Perinatal Research, The Research Institute at Nationwide Children s Hospital, Columbus, OH, USA Department of Surgery, the Second Hospital of Shandong University, Jinan, Shandong, China
    Life Sci 148:31-40. 2016
    ..The aims of the present study seek to determine which catalase(s) plays a predominant role in determining the resistance to H2O2, and to assess the role of catalase in Acinetobacter virulence...
  12. pmc Bacterial differentiation, development, and disease: mechanisms for survival
    Sheryl S Justice
    Center for Microbial Pathogenesis, The Research Institute at Nationwide Children s Hospital, Columbus, OH, USA The Ohio State University School of Medicine, Columbus, OH, USA
    FEMS Microbiol Lett 360:1-8. 2014
    ..We will also offer insight into the mechanism underlying the morphological changes and how these morphotypes aid in persistence. Additional examples of morphological changes associated with survival will be presented. ..