Affiliation: National Institutes of Health
- Epigenetic drugs can stimulate metastasis through enhanced expression of the pro-metastatic Ezrin geneYanlin Yu
Laboratory of Cancer Biology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
PLoS ONE 5:e12710. 2010....
- The homeoprotein six1 transcriptionally activates multiple protumorigenic genes but requires ezrin to promote metastasisYanlin Yu
Laboratory of Cell Regulation and Carcinogenesis, National Cancer Institute, NIH, Bethesda, Maryland 20892 4264, USA
Cancer Res 66:1982-9. 2006..Our data indicate that Ezrin represents a promising therapeutic target for patients with advanced-stage rhabdomyosarcoma and perhaps other malignancies...
- Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulatorsYanlin Yu
Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
Nat Med 10:175-81. 2004..The identification of ezrin and Six-1 as critical regulators of metastasis in RMS provides new mechanistic and therapeutic insights into this pediatric cancer...