R Vermeulen

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Biological monitoring of carbon disulphide and phthalate exposure in the contemporary rubber industry
    Roel Vermeulen
    Division of Cancer Epidemiology and Genetics, Occupational and Environmental Epidemiology Branch, National Cancer Institute, NIH, DHHS, 6120 Executive Boulevard, Rockville, MD 20852, USA
    Int Arch Occup Environ Health 78:663-9. 2005
  2. ncbi request reprint A study on immunological responses to exposures encountered in corn farming
    R Vermeulen
    Division of Cancer Epidemiology and Genetics, NCI, Rockville, MD 20892, USA
    J Biochem Mol Toxicol 19:172. 2005
  3. pmc Historical limitations of determinant based exposure groupings in the rubber manufacturing industry
    R Vermeulen
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20892, USA
    Occup Environ Med 62:793-9. 2005
  4. ncbi request reprint Urothelial cell DNA adducts in rubber workers
    Roel Vermeulen
    Environmental and Occupational Health Group, Institute of Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Environ Mol Mutagen 39:306-13. 2002
  5. pmc Decreased levels of CXC-chemokines in serum of benzene-exposed workers identified by array-based proteomics
    Roel Vermeulen
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Boulevard, Rockville, MD 20852, USA
    Proc Natl Acad Sci U S A 102:17041-6. 2005
  6. pmc Respiratory symptoms and occupation: a cross-sectional study of the general population
    Roel Vermeulen
    Environmental and Occupational Health Division, Institute for Risk Assessment Sciences, University Utrecht, Utrecht, PO Box 80176, 3503 TD Utrecht, The Netherlands
    Environ Health 1:5. 2002
  7. ncbi request reprint Dermal exposure assessment in occupational epidemiologic research
    Roel Vermeulen
    Occupational Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville, MD 20892, USA
    Scand J Work Environ Health 28:371-85. 2002
  8. ncbi request reprint Detailed exposure assessment for a molecular epidemiology study of benzene in two shoe factories in China
    Roel Vermeulen
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Boulevard, Rockville, MD 20892, USA
    Ann Occup Hyg 48:105-16. 2004
  9. ncbi request reprint Exposure to inhalable dust and its cyclohexane soluble fraction since the 1970s in the rubber manufacturing industry in the European Union
    F de Vocht
    Environmental Epidemiology Division, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Occup Environ Med 65:384-91. 2008
  10. ncbi request reprint Mutagenic exposure in the rubber manufacturing industry: an industry wide survey
    R Vermeulen
    Environmental and Occupational Health Group, Institute of Risk Assessment Sciences, Utrecht University, P.O. Box 238, 6700 AE, Wageningen, The Netherlands
    Mutat Res 490:27-34. 2001

Collaborators

Detail Information

Publications60

  1. ncbi request reprint Biological monitoring of carbon disulphide and phthalate exposure in the contemporary rubber industry
    Roel Vermeulen
    Division of Cancer Epidemiology and Genetics, Occupational and Environmental Epidemiology Branch, National Cancer Institute, NIH, DHHS, 6120 Executive Boulevard, Rockville, MD 20852, USA
    Int Arch Occup Environ Health 78:663-9. 2005
    ....
  2. ncbi request reprint A study on immunological responses to exposures encountered in corn farming
    R Vermeulen
    Division of Cancer Epidemiology and Genetics, NCI, Rockville, MD 20892, USA
    J Biochem Mol Toxicol 19:172. 2005
  3. pmc Historical limitations of determinant based exposure groupings in the rubber manufacturing industry
    R Vermeulen
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20892, USA
    Occup Environ Med 62:793-9. 2005
    ..To study the validity of using a cross-sectional industry-wide exposure survey to develop exposure groupings for epidemiological purposes that extend beyond the time period in which the exposure data were collected...
  4. ncbi request reprint Urothelial cell DNA adducts in rubber workers
    Roel Vermeulen
    Environmental and Occupational Health Group, Institute of Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Environ Mol Mutagen 39:306-13. 2002
    ..Larger studies among rubber workers should be conducted to study in more detail the potential carcinogenicity of exposures encountered in these work areas...
  5. pmc Decreased levels of CXC-chemokines in serum of benzene-exposed workers identified by array-based proteomics
    Roel Vermeulen
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Boulevard, Rockville, MD 20852, USA
    Proc Natl Acad Sci U S A 102:17041-6. 2005
    ....
  6. pmc Respiratory symptoms and occupation: a cross-sectional study of the general population
    Roel Vermeulen
    Environmental and Occupational Health Division, Institute for Risk Assessment Sciences, University Utrecht, Utrecht, PO Box 80176, 3503 TD Utrecht, The Netherlands
    Environ Health 1:5. 2002
    ..Subjects were from the Dutch Monitoring Project on Risk Factors for Chronic Diseases (MORGEN). The composition of this population enabled estimation of respiratory risks due to occupation from the recent past for both men and women...
  7. ncbi request reprint Dermal exposure assessment in occupational epidemiologic research
    Roel Vermeulen
    Occupational Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville, MD 20892, USA
    Scand J Work Environ Health 28:371-85. 2002
    ....
  8. ncbi request reprint Detailed exposure assessment for a molecular epidemiology study of benzene in two shoe factories in China
    Roel Vermeulen
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Boulevard, Rockville, MD 20892, USA
    Ann Occup Hyg 48:105-16. 2004
    ..Our goal was to identify workers with a broad range of benzene exposures, for an epidemiologic study relating exposure to early biologic effects...
  9. ncbi request reprint Exposure to inhalable dust and its cyclohexane soluble fraction since the 1970s in the rubber manufacturing industry in the European Union
    F de Vocht
    Environmental Epidemiology Division, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Occup Environ Med 65:384-91. 2008
    ....
  10. ncbi request reprint Mutagenic exposure in the rubber manufacturing industry: an industry wide survey
    R Vermeulen
    Environmental and Occupational Health Group, Institute of Risk Assessment Sciences, Utrecht University, P.O. Box 238, 6700 AE, Wageningen, The Netherlands
    Mutat Res 490:27-34. 2001
    ..Detection of substantial mutagenic activity on possible contact surfaces supports furthermore the potential importance of the dermal route in the uptake of genotoxic compounds of workers in the rubber manufacturing industry...
  11. doi request reprint Modelling indoor electromagnetic fields (EMF) from mobile phone base stations for epidemiological studies
    J Beekhuizen
    Institute for Risk Assessment Sciences IRAS, Division Environmental Epidemiology, Utrecht University, Yalelaan 2, 3584 CM, Utrecht, The Netherlands
    Environ Int 67:22-6. 2014
    ..Although there is exposure misclassification, we conclude that it is feasible to reliably rank indoor RF-EMF from mobile phone base stations for epidemiological studies. ..
  12. pmc Exposure related mutagens in urine of rubber workers associated with inhalable particulate and dermal exposure
    R Vermeulen
    Environmental and Occupational Health Division, Institute of Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Occup Environ Med 60:97-103. 2003
    ..To determine the relation of the inhalation and dermal exposure routes and mutagenic activity in the urine of rubber workers (n = 105)...
  13. pmc Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity
    H D Hosgood
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 7240, USA
    Occup Environ Med 66:848-53. 2009
    ..Benzene is an established human haematotoxin, with substantial interindividual variation in benzene-induced toxicity...
  14. ncbi request reprint Occupational exposure to NDMA and NMor in the European rubber industry
    F de Vocht
    Environmental Epidemiology Division, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    J Environ Monit 9:253-9. 2007
    ..Although average levels are well below the current limits exposure has not been eliminated, and incidental high exposures do still occur...
  15. doi request reprint Indoor concentrations of nitrogen dioxide and sulfur dioxide from burning solid fuels for cooking and heating in Yunnan Province, China
    W J Seow
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA
    Indoor Air 26:776-83. 2016
    ..Model construction indicated that the measurements of both pollutants were influenced by stove design. This exposure assessment study has identified high levels of NO2 and SO2 as a result of burning solid fuels for cooking and heating. ..
  16. ncbi request reprint Postulating a dermal pathway for exposure to anti-neoplastic drugs among hospital workers. Applying a conceptual model to the results of three workplace surveys
    H Kromhout
    Environmental and Occupational Health Group, Utrecht University, P O Box 238, 6700 AE, Wageningen, The Netherlands
    Ann Occup Hyg 44:551-60. 2000
    ..Estimation of all relevant mass transport rates will be a challenge for the near future...
  17. ncbi request reprint Temporal, personal and spatial variability in dermal exposure
    H Kromhout
    Institute of Risk Assessment Sciences, Environmental and Occupational Health Group, Utrecht University, Utrecht, The Netherlands
    Ann Occup Hyg 45:257-73. 2001
    ..Day-to-day variability in dermal exposure levels appeared to be significant for specific locations, but not for the average of several body-location. Underlying exposure scenarios (transfer and deposition) also played an important role...
  18. pmc Application of OMICS technologies in occupational and environmental health research; current status and projections
    J Vlaanderen
    Institute for Risk Assessment Sciences, Division of Environmental Epidemiology, University Utrecht, PO Box 80178, 3508 TD, Utrecht, The Netherlands
    Occup Environ Med 67:136-43. 2010
    ..To illustrate the current status of the application of OMICS in OEH research, we will provide examples of studies that used OMICS technologies to investigate human health effects of two well-known toxicants, benzene and arsenic...
  19. ncbi request reprint Dermal exposure, handwashing, and hand dermatitis in the rubber manufacturing industry
    R Vermeulen
    Environmental and Occupational Health Group, Institute for Risk Assessment Sciences, Utrecht University, P.O. Box 238, 6700 AE Wageningen, The Netherlands
    Epidemiology 12:350-4. 2001
    ..27 (95% confidence interval = 0.90-20.27) and odds ratio = 6.38 (95% confidence interval = 1.33-30.17, respectively)]...
  20. doi request reprint Cause-specific mortality of Dutch chlorophenoxy herbicide manufacturing workers
    D Boers
    Utrecht University, Institute for Risk Assessment Sciences, Department of Environmental Epidemiology, PO Box 80178, 3508 TD, Utrecht, The Netherlands
    Occup Environ Med 67:24-31. 2010
    ..Previously, we have shown elevated risks for mortality and cancer mortality in this cohort. The purpose of the current, third follow-up, is to provide an updated assessment of cause-specific mortality for both factories...
  21. doi request reprint Geospatial modelling of electromagnetic fields from mobile phone base stations
    J Beekhuizen
    Institute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, Jenalaan 18d, 3584 CK, Utrecht, The Netherlands
    Sci Total Environ 445:202-9. 2013
    ..07 V/m, and slightly overestimated the UMTS field strengths by 0.01 V/m. NISMap provides a reliable way of assessing environmental RF-EMF exposure for epidemiological studies of RF-EMF and health in urban areas...
  22. ncbi request reprint Coal combustion and lung cancer risk in XuanWei: a possible role of silica?
    R Vermeulen
    Division of Environmental Epidemiology, Institute for Risk Assessment Sciences, Utrecht University, The Netherlands
    Med Lav 102:362-7. 2011
    ..Research to date has suggested that exposure to polycyclic aromatic hydrocarbons (PAHs) is one of the main contributors to the observed risk. More recently exposure to crystalline silica has been suggested as another contributing factor...
  23. pmc Non-Hodgkin lymphoma and occupational exposures: multiple exposures not = multiple papers
    H Kromhout
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, Netherlands
    Occup Environ Med 64:4-5. 2007
  24. pmc Outdoor, indoor, and personal black carbon exposure from cookstoves burning solid fuels
    G S Downward
    Institute for Risk Assessment Sciences, Division of Environmental Epidemiology, Utrecht University, Utrecht, The Netherlands
    Indoor Air 26:784-95. 2016
    ..This provides valuable insight into potential morbidity, mortality, and climate change contributions of domestic usage of solid fuels. ..
  25. ncbi request reprint A database of exposures in the rubber manufacturing industry: design and quality control
    Frank de Vocht
    Environmental and Occupational Health Division, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Ann Occup Hyg 49:691-701. 2005
    ....
  26. ncbi request reprint Carcinogen biomonitoring in human exposures and laboratory research: validation and application to human occupational exposures
    Glenn Talaska
    The Department of Environmental Health, The University of Cincinnati College of Medicine, Cincinnati, OH 45267 0056, USA
    Toxicol Lett 134:39-49. 2002
    ..These data reinforce the notion that carcinogen biomarkers are useful to monitor exposure, but that a complementary approaches involving effect and perhaps susceptibility biomarkers is necessary to obtain the necessary information...
  27. ncbi request reprint Multiple biomarkers study in painters in a shipyard in Korea
    Kyoung Ho Lee
    Department of Preventive Medicine, Institute of Environmental Medicine, Seoul National University College of Medicine, SNUMRC, 28 Yongon Dong, Chongno Gu, Seoul 110 799, South Korea
    Mutat Res 540:89-98. 2003
    ..These results suggest that painters in the shipyard were exposed to significant amounts of PAHs and possibly to other genotoxic aromatic compounds, and that urinary 1-OHPG may be a potential biomarker of PAH exposure in this population...
  28. ncbi request reprint Variability of task-based dermal exposure measurements from a variety of workplaces
    Hans Kromhout
    Environmental and Occupational Health Division, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Ann Occup Hyg 48:187-96. 2004
    ....
  29. ncbi request reprint Dermal exposure assessment to benzene and toluene using charcoal cloth pads
    Berna van Wendel de Joode
    Department of Chemical Exposure Assessment, TNO Chemistry, Zeist, The Netherlands
    J Expo Anal Environ Epidemiol 15:47-50. 2005
    ..This design would most likely result in a better ability to correct for airborne concentrations at a given body location...
  30. pmc Hematotoxicity in workers exposed to low levels of benzene
    Qing Lan
    Division of Cancer Epidemiology and Genetics, National Cancer Institute NCI, National Institutes of Health NIH, Department of Health and Human Services DHHS, Bethesda, MD 20892, USA
    Science 306:1774-6. 2004
    ..Thus, hematotoxicity from exposure to benzene occurred at air levels of 1 ppm or less and may be particularly evident among genetically susceptible subpopulations...
  31. doi request reprint Polycyclic aromatic hydrocarbon exposure, urinary mutagenicity, and DNA adducts in rubber manufacturing workers
    Susan Peters
    Environmental Epidemiology Division, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Cancer Epidemiol Biomarkers Prev 17:1452-9. 2008
    ..Presently, we investigated whether DNA adducts in peripheral blood mononuclear cells (PBMC) and/or urothelial cells may be caused by polycyclic aromatic hydrocarbons or other genotoxic compounds...
  32. pmc Association between mitochondrial DNA copy number, blood cell counts, and occupational benzene exposure
    Min Shen
    Division of Cancer Epidemiology and Genetics, NCI, NIH, DHHS, Bethesda, Maryland 20892 7240, USA
    Environ Mol Mutagen 49:453-7. 2008
    ..Benzene exposure may induce mtDNA amplification, possibly in response to oxidative stress caused by benzene. The finding needs to be replicated by other studies...
  33. pmc Occupation and chronic bronchitis among Chinese women
    Srmena Krstev
    Occupational and Environmental Epidemiology Branch, National Cancer Institute, National Institutes of Health DHHS, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    J Occup Environ Med 50:64-71. 2008
    ..To examine the association between occupation and chronic bronchitis among a cross section of Chinese women who participated in the Shanghai Women's Health Study...
  34. ncbi request reprint Bulky DNA adduct formation and risk of bladder cancer
    Gemma Castano-Vinyals
    Centre for Research in Environmental Epidemiology, Institut Municipal d Investigacio Medica, Doctor Aiguader, 88, 08003 Barcelona, Spain
    Cancer Epidemiol Biomarkers Prev 16:2155-9. 2007
    ..Results do not support an association of bladder cancer risk with low-level exposure to PAHs as measured through the formation of bulky DNA adducts in peripheral mononuclear cells...
  35. ncbi request reprint Chromosome damage and cancer risk in the workplace: the example of cytogenetic surveillance in Croatia
    Aleksandra Fucic
    Institute for Medical Research and Occupational Health, Ksaverska c 2, Zagreb, Croatia
    Toxicol Lett 172:4-11. 2007
    ..61-4.72). Recommendations for future strategies comprise the inclusion of predictive biomarkers in surveillance programs, the definition of a regulatory framework, and their possible use for the identification of individual risk profiles...
  36. ncbi request reprint Evaluation of two self-administered questionnaires to ascertain dermatitis among metal workers and its relation with exposure to metal working fluids
    Berna van Wendel de Joode
    Risk Assessment in the Work Environment, a collaborative centre between TNO Quality of Life and IRAS Utrecht University, Utrecht, The Netherlands
    Contact Dermatitis 57:14-20. 2007
    ..Alternatively, it would be preferable to apply the symptom-based questionnaire; workers with symptoms should be seen by a dermatologist to identify false positives...
  37. pmc Albumin adducts of electrophilic benzene metabolites in benzene-exposed and control workers
    Yu Sheng Lin
    Department of Environmental Sciences and Engineering, School of Public Health, University of North Carolina, Chapel Hill, North Carolina 27599 7431, USA
    Environ Health Perspect 115:28-34. 2007
    ..Metabolism of benzene produces reactive electrophiles, including benzene oxide (BO), 1,4-benzoquinone (1,4-BQ), and 1,2-benzoquinone (1,2-BQ), that are capable of reacting with blood proteins to produce adducts...
  38. ncbi request reprint Occupation and adult-onset asthma among Chinese women in a population-based cohort
    Srmena Krstev
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland 20892, USA
    Am J Ind Med 50:265-73. 2007
    ..We examined the associations between occupation and asthma among women in a case-control study nested in the population-based Shanghai Women's Health Study cohort in China...
  39. ncbi request reprint Use of 'Omic' technologies to study humans exposed to benzene
    Martyn T Smith
    School of Public Health, 140 Warren Hall, University of California, Berkeley, CA 94720 7360, USA
    Chem Biol Interact 153:123-7. 2005
    ..Omic technologies therefore have significant potential in generating novel biomarkers of exposure, susceptibility and response to benzene...
  40. pmc Discovery of novel biomarkers by microarray analysis of peripheral blood mononuclear cell gene expression in benzene-exposed workers
    Matthew S Forrest
    School of Public Health, University of California, Berkeley, California 94720 7360, USA
    Environ Health Perspect 113:801-7. 2005
    ..Thus, microarray analysis along with real-time PCR confirmation reveals that altered expressions of CXCL16, ZNF331, JUN, and PF4 are potential biomarkers of benzene exposure...
  41. ncbi request reprint Modeling human metabolism of benzene following occupational and environmental exposures
    Sungkyoon Kim
    School of Public Health, University of North Carolina, CB 7431, Chapel Hill, NC 27599
    Cancer Epidemiol Biomarkers Prev 15:2246-52. 2006
    ..Our results also suggest that GLM + NS models are ideal for evaluating nonlinear relationships between environmental exposures and levels of human biomarkers...
  42. ncbi request reprint Polymorphisms in cytokine and cellular adhesion molecule genes and susceptibility to hematotoxicity among workers exposed to benzene
    Qing Lan
    Division of Cancer Epidemiology, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, MD 20892 7240, USA
    Cancer Res 65:9574-81. 2005
    ..041) and increased (P = 0.076) CFU-GEMM progenitor cell colony formation in 29 benzene-exposed workers. This is the first report to provide evidence that SNPs in genes that regulate hematopoiesis influence benzene-induced hematotoxicity...
  43. ncbi request reprint Assessment of dermal exposure to benzene and toluene in shoe manufacturing by activated carbon cloth patches
    Roel Vermeulen
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20892, USA
    J Environ Monit 8:1143-8. 2006
    ..The aim of this investigation was to use activated carbon cloth (ACC) patches to study the probability and extent of dermal exposure to benzene and toluene in a shoe factory...
  44. ncbi request reprint Use of OctoChrome fluorescence in situ hybridization to detect specific aneuploidy among all 24 chromosomes in benzene-exposed workers
    Luoping Zhang
    School of Public Health, 140 Warren Hall, University of California, Berkeley, CA 94720 7360, USA
    Chem Biol Interact 153:117-22. 2005
    ..We are currently investigating potential mechanisms for this induction of selective aneuploidy...
  45. pmc Impaired lung function and lung cancer incidence in a cohort of Swedish construction workers
    Mark P Purdue
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, EPS 8121, 6120 Executive Blvd, Bethesda, MD 20892 7240, USA
    Thorax 62:51-6. 2007
    ..To deal with this question further, data from a large (n = 176 997) cohort of male Swedish construction workers, for whom spirometry measurements before follow-up were available, were analysed...
  46. ncbi request reprint Leukocyte polycyclic aromatic hydrocarbon-DNA adduct formation and colorectal adenoma
    Marc J Gunter
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Division of Health and Human Services, Bethesda, MD 20852, USA
    Carcinogenesis 28:1426-9. 2007
    ..8 (95% CI, 1.2-6.5; P(trend) = 0.048) for risk of colorectal adenoma. These data support a link between PAH exposure and colorectal adenoma...
  47. ncbi request reprint Polymorphisms in genes involved in DNA double-strand break repair pathway and susceptibility to benzene-induced hematotoxicity
    Min Shen
    Division of Cancer Epidemiology and Genetics, NCI, NIH, DHHS, Bethesda, MD 20892, USA
    Carcinogenesis 27:2083-9. 2006
    ..The effect of BRCA2 Ex11 +1487 A > G polymorphism was limited to granulocytes. These results suggest that genetic polymorphisms in WRN, TP53 and BRCA2 that maintain genomic stability impact benzene-induced hematotoxicity...
  48. ncbi request reprint Lymphocyte toxicity and T cell receptor excision circles in workers exposed to benzene
    Qing Lan
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Blvd, EPS 8109, Bethesda, MD 20892 7240, USA
    Chem Biol Interact 153:111-5. 2005
    ..Although our study does not rule out counterbalancing alterations of TREC levels in specific T cell subsets, benzene's lymphotoxicity does not appear to be mediated through diminished thymus function...
  49. pmc Chromosomal aberration frequency in lymphocytes predicts the risk of cancer: results from a pooled cohort study of 22 358 subjects in 11 countries
    Stefano Bonassi
    Unit of Molecular Epidemiology, National Cancer Research Institute, Genoa, Italy
    Carcinogenesis 29:1178-83. 2008
    ..These results reinforce the evidence of a link between CA frequency and cancer risk and provide novel information on the role of aberration subclass and cancer type...
  50. ncbi request reprint DREAM: a method for semi-quantitative dermal exposure assessment
    Berna van-Wendel-de-Joode
    TNO Chemistry, Department of Chemical Exposure Assessment, PO Box 360, 3700 AJ Zeist, The Netherlands
    Ann Occup Hyg 47:71-87. 2003
    ..DREAM could be a promising approach for structured, semi-quantitative, dermal exposure assessment...
  51. pmc Applying new biotechnologies to the study of occupational cancer--a workshop summary
    Mark Toraason
    National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Cincinnati, OH 45226, USA
    Environ Health Perspect 112:413-6. 2004
    ..The workshop focused on identifying and interpreting markers for early biologic effect and inherited modifiers of risk...
  52. ncbi request reprint Occupational dermal exposure to cyclophosphamide in Dutch hospitals: a pilot study
    Wouter Fransman
    Environmental and Occupational Health Group, Institute for Risk Assessment Sciences, Utrecht University, PO Box 80176, 3508 TD Utrecht, The Netherlands
    Ann Occup Hyg 48:237-44. 2004
    ..In this pilot study we assessed potential and actual dermal exposure for several common hospital tasks. Results were used to derive an optimal measurement strategy for a currently ongoing exposure survey...
  53. ncbi request reprint Using urinary biomarkers to elucidate dose-related patterns of human benzene metabolism
    Sungkyoon Kim
    School of Public Health, University of North Carolina, Chapel Hill, NC 27599, and National Cancer Institute NCI, National Institutes of Health NIH, Department of Health and Human Services DHHS, Bethesda, MD 20892, USA
    Carcinogenesis 27:772-81. 2006
    ..027 and 15.4 p.p.m. Reductions in metabolite production were most pronounced for CA and PH<1 p.p.m., indicating that metabolism favored production of the toxic metabolites, HQ and MA, at low exposures...
  54. ncbi request reprint NTP-CERHR Expert Panel Report on the reproductive and developmental toxicity of styrene
    Ulrike Luderer
    University of California Irvine, Irvine, CA, USA
    Birth Defects Res B Dev Reprod Toxicol 77:110-93. 2006
  55. ncbi request reprint Chromosomal aberrations and cancer risk: results of a cohort study from Central Europe
    Paolo Boffetta
    International Agency for Research on Cancer, Lyon, France
    Am J Epidemiol 165:36-43. 2007
    ....
  56. ncbi request reprint Human population studies with cytogenetic biomarkers: review of the literature and future prospectives
    Stefano Bonassi
    Unit of Environmental Epidemiology and Biostatistics, National Cancer Research Institute, Genoa, Italy
    Environ Mol Mutagen 45:258-70. 2005
    ..The role of susceptibility and its potential impact on genotoxic damage are discussed with special attention to the effect of major genetic polymorphisms on the baseline frequency of CAs and micronuclei...
  57. ncbi request reprint Genetic polymorphisms and benzene metabolism in humans exposed to a wide range of air concentrations
    Sungkyoon Kim
    School of Public Health, University of North Carolina, Chapel Hill, NC 27599, USA
    Pharmacogenet Genomics 17:789-801. 2007
    ....
  58. ncbi request reprint Air pollution and risk of urinary bladder cancer in a case-control study in Spain
    Gemma Castano-Vinyals
    Gemma CastaƱo Vinyals, Centre for Research in Environmental Epidemiology CREAL, Municipal Institute of Medical Research, C Doctor Aiguader, 88, Barcelona 08003, Spain
    Occup Environ Med 65:56-60. 2008
    ..Air pollution has been associated with an increased risk for lung cancer. We examined whether long-term air pollution is associated with bladder cancer risk...
  59. ncbi request reprint Evaluation of 2 self-administered questionnaires to ascertain dermatitis among metal workers and its relation with exposure to metalworking fluids
    Berna van Wendel de Joode
    Risk Assessment in the Work Environment, TNO Quality of Life and IRAS Utrecht University, 3508 TD Utrecht, The Netherlands
    Contact Dermatitis 56:311-7. 2007
    ..Alternatively, it would be preferable applying the symptom-based questionnaire; workers with symptoms should be seen by a dermatologist to identify false positives...
  60. ncbi request reprint Dermal exposure to cyclophosphamide in hospitals during preparation, nursing and cleaning activities
    Wouter Fransman
    Environmental and Occupational Health Division, Institute for Risk Assessment Sciences IRAS, Utrecht University, Utrecht, The Netherlands
    Int Arch Occup Environ Health 78:403-12. 2005
    ....