Donn M Stewart

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint A case of X-linked agammaglobulinemia diagnosed in adulthood
    D M Stewart
    Metabolism Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Clin Immunol 99:94-9. 2001
  2. ncbi request reprint The clinical spectrum of Bruton's agammaglobulinemia
    D M Stewart
    Metabolism Branch, National Cancer Institute, National Institutes of Health, 10 Center Drive, MSC 1374, Bethesda, MD 20892 1374, USA
    Curr Allergy Asthma Rep 1:558-65. 2001
  3. ncbi request reprint B lymphocytes from individuals with common variable immunodeficiency respond to B lymphocyte stimulator (BLyS protein) in vitro
    Donn M Stewart
    Metabolism Branch, NCI, NIH, 10 Center Drive MSC 1374, Bethesda, MD 20892, USA
    Clin Immunol 109:137-43. 2003
  4. ncbi request reprint The phenomenon of spontaneous genetic reversions in the Wiskott-Aldrich syndrome: a report of the workshop of the ESID Genetics Working Party at the XIIth Meeting of the European Society for Immunodeficiencies (ESID). Budapest, Hungary October 4-7, 2006
    Donn M Stewart
    Immunophysiology Section, Metabolism Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Clin Immunol 27:634-9. 2007
  5. doi request reprint X-linked hypogammaglobulinemia and isolated growth hormone deficiency: an update
    Donn M Stewart
    Immunophysiology Section, Metabolism Branch, CCR, NCI, National Institute of Health, Bldg 10, Bethesda, MD 20892, USA
    Immunol Res 40:262-70. 2008
  6. ncbi request reprint X-linked hypogammaglobulinemia and isolated growth hormone deficiency: an update
    Donn M Stewart
    Immunophysiology Section, Metabolism Branch, NCI, NIH, National Institutes of Health, Bldg 10, Rm 4N115, MSC 1374, Bethesda, MD 20892, USA
    Immunol Res 38:391-9. 2007
  7. ncbi request reprint Update on X-linked hypogammaglobulinemia with isolated growth hormone deficiency
    Donn M Stewart
    Metabolism Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA, and Department of Pediatrics, University of Brescia, Italy
    Curr Opin Allergy Clin Immunol 5:510-2. 2005
  8. pmc Safety, efficacy, and pharmacokinetics/pharmacodynamics of daclizumab (anti-CD25) in patients with adult T-cell leukemia/lymphoma
    Jonathan L Berkowitz
    Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Clin Immunol 155:176-87. 2014
  9. pmc 90Y-daclizumab, an anti-CD25 monoclonal antibody, provided responses in 50% of patients with relapsed Hodgkin's lymphoma
    John E Janik
    Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892
    Proc Natl Acad Sci U S A 112:13045-50. 2015
  10. pmc Phase 1 trial of IL-15 trans presentation blockade using humanized Mikβ1 mAb in patients with T-cell large granular lymphocytic leukemia
    Thomas A Waldmann
    Metabolism Branch, Center for Cancer Research, National Cancer Institute NCI, National Institutes of Health NIH, Bethesda, MD 20892, USA
    Blood 121:476-84. 2013

Collaborators

Detail Information

Publications13

  1. ncbi request reprint A case of X-linked agammaglobulinemia diagnosed in adulthood
    D M Stewart
    Metabolism Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Clin Immunol 99:94-9. 2001
    ..In vitro kinase assay of this product showed weak kinase activity, perhaps resulting in milder than usual disease. XLA can present in adult males, and sporadic cases may be misdiagnosed as CVID...
  2. ncbi request reprint The clinical spectrum of Bruton's agammaglobulinemia
    D M Stewart
    Metabolism Branch, National Cancer Institute, National Institutes of Health, 10 Center Drive, MSC 1374, Bethesda, MD 20892 1374, USA
    Curr Allergy Asthma Rep 1:558-65. 2001
    ..We conclude that any male with hypogammaglobulinemia, regardless of age of presentation, might have XLA. Males with low B-cell numbers are particularly likely to have XLA and should have Bruton's tyrosine kinase levels assessed...
  3. ncbi request reprint B lymphocytes from individuals with common variable immunodeficiency respond to B lymphocyte stimulator (BLyS protein) in vitro
    Donn M Stewart
    Metabolism Branch, NCI, NIH, 10 Center Drive MSC 1374, Bethesda, MD 20892, USA
    Clin Immunol 109:137-43. 2003
    ..These results suggest that BLyS induces proliferative and Ig-secretory responses in B lymphocytes isolated from some CVID patients and lend support to its potential use in therapy of this disorder...
  4. ncbi request reprint The phenomenon of spontaneous genetic reversions in the Wiskott-Aldrich syndrome: a report of the workshop of the ESID Genetics Working Party at the XIIth Meeting of the European Society for Immunodeficiencies (ESID). Budapest, Hungary October 4-7, 2006
    Donn M Stewart
    Immunophysiology Section, Metabolism Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Clin Immunol 27:634-9. 2007
    ..Many different cell lineages showed reversions. These data form the foundation for further investigation into this phenomenon, which has implications for therapy of this disease...
  5. doi request reprint X-linked hypogammaglobulinemia and isolated growth hormone deficiency: an update
    Donn M Stewart
    Immunophysiology Section, Metabolism Branch, CCR, NCI, National Institute of Health, Bldg 10, Bethesda, MD 20892, USA
    Immunol Res 40:262-70. 2008
    ..The current review summarizes the clinical, laboratory, and genetic features of the disease as they have unfolded over the past quarter-century since its description...
  6. ncbi request reprint X-linked hypogammaglobulinemia and isolated growth hormone deficiency: an update
    Donn M Stewart
    Immunophysiology Section, Metabolism Branch, NCI, NIH, National Institutes of Health, Bldg 10, Rm 4N115, MSC 1374, Bethesda, MD 20892, USA
    Immunol Res 38:391-9. 2007
    ..The current review summarizes the clinical, laboratory and genetic features of the disease as they have unfolded over the past quarter century since its description...
  7. ncbi request reprint Update on X-linked hypogammaglobulinemia with isolated growth hormone deficiency
    Donn M Stewart
    Metabolism Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA, and Department of Pediatrics, University of Brescia, Italy
    Curr Opin Allergy Clin Immunol 5:510-2. 2005
    ..To provide an update on the syndrome X-linked hypogammaglobulinemia with isolated growth hormone deficiency, focusing on the pedigree described originally...
  8. pmc Safety, efficacy, and pharmacokinetics/pharmacodynamics of daclizumab (anti-CD25) in patients with adult T-cell leukemia/lymphoma
    Jonathan L Berkowitz
    Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Clin Immunol 155:176-87. 2014
    ..g., multiple sclerosis) since high-dose daclizumab is required to saturate IL-2R alpha in extravascular sites...
  9. pmc 90Y-daclizumab, an anti-CD25 monoclonal antibody, provided responses in 50% of patients with relapsed Hodgkin's lymphoma
    John E Janik
    Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892
    Proc Natl Acad Sci U S A 112:13045-50. 2015
    ..In conclusion, repeated (90)Y-daclizumab infusions directed predominantly toward nonmalignant T cells rosetting around Reed-Sternberg cells provided meaningful therapy for select HL patients. ..
  10. pmc Phase 1 trial of IL-15 trans presentation blockade using humanized Mikβ1 mAb in patients with T-cell large granular lymphocytic leukemia
    Thomas A Waldmann
    Metabolism Branch, Center for Cancer Research, National Cancer Institute NCI, National Institutes of Health NIH, Bethesda, MD 20892, USA
    Blood 121:476-84. 2013
    ....
  11. pmc High-Throughput GoMiner, an 'industrial-strength' integrative gene ontology tool for interpretation of multiple-microarray experiments, with application to studies of Common Variable Immune Deficiency (CVID)
    Barry R Zeeberg
    Genomics and Bioinformatics Group, Laboratory of Molecular Pharmacology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    BMC Bioinformatics 6:168. 2005
    ..We wanted to provide a computational resource that automates the analysis of multiple microarrays and then integrates the results across all of them in useful exportable output files and visualizations...
  12. ncbi request reprint Tracking gene expression in primary immunodeficiencies
    Haiying Qin
    National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Curr Opin Allergy Clin Immunol 3:437-42. 2003
    ..The application of this technology has been found to accelerate the discovery rate of gene expression disturbances in primary immunodeficiency diseases and provide potential molecular diagnostic tools...
  13. ncbi request reprint Myofibroblastic tumor of the lower lip in a patient with X-linked hypogammaglobulinemia and isolated growth hormone deficiency: a case report
    Matin M Imanguli
    Clinical Research Cores, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA
    J Oral Maxillofac Surg 65:1219-22. 2007