Stanislav V Sosnovtsev

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Identification of Human Junctional Adhesion Molecule 1 as a Functional Receptor for the Hom-1 Calicivirus on Human Cells.
    Stanislav V Sosnovtsev
    MBio 8:. 2017
  2. pmc Processing map and essential cleavage sites of the nonstructural polyprotein encoded by ORF1 of the feline calicivirus genome
    Stanislav V Sosnovtsev
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892 8007, USA
    J Virol 76:7060-72. 2002
  3. pmc Cleavage map and proteolytic processing of the murine norovirus nonstructural polyprotein in infected cells
    Stanislav V Sosnovtsev
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 8007, USA
    J Virol 80:7816-31. 2006
  4. pmc Feline calicivirus VP2 is essential for the production of infectious virions
    Stanislav V Sosnovtsev
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 50 South Drive MSC8007, Building 50, Room 6316, Bethesda, MD 20892 8007, USA
    J Virol 79:4012-24. 2005
  5. ncbi request reprint Identification and genomic mapping of the ORF3 and VPg proteins in feline calicivirus virions
    S V Sosnovtsev
    Laboratory of Infectious Diseases, National Institute of Allergies and Infectious Diseases, Bethesda, Maryland, 20892, USA
    Virology 277:193-203. 2000
  6. ncbi request reprint Feline calicivirus replication induces apoptosis in cultured cells
    Stanislav V Sosnovtsev
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 50 South Drive MSC8007, Building 50, Room 6316, Bethesda, MD 20892 8007, USA
    Virus Res 94:1-10. 2003
  7. pmc Reverse genetics system for porcine enteric calicivirus, a prototype sapovirus in the Caliciviridae
    Kyeong Ok Chang
    Laboratory of Infectious Diseases, National Institutes of Health DHHS, NIAID LID, Bldg 50, Room 6316, 9000 Rockville Pike, Bethesda, MD 20892 8026, USA
    J Virol 79:1409-16. 2005
  8. doi request reprint Mapping and modeling of a strain-specific epitope in the Norwalk virus capsid inner shell
    Gabriel I Parra
    Caliciviruses Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    Virology 492:232-41. 2016
  9. pmc The feline calicivirus leader of the capsid protein is associated with cytopathic effect
    Eugenio J Abente
    Laboratory of Infectious Diseases, NIAID, NIH, Bethesda, MD, USA
    J Virol 87:3003-17. 2013
  10. pmc Diversity of murine norovirus strains isolated from asymptomatic mice of different genetic backgrounds within a single U.S. research institute
    Elyssa L Barron
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America
    PLoS ONE 6:e21435. 2011

Collaborators

Detail Information

Publications31

  1. pmc Identification of Human Junctional Adhesion Molecule 1 as a Functional Receptor for the Hom-1 Calicivirus on Human Cells.
    Stanislav V Sosnovtsev
    MBio 8:. 2017
    ..The Hom-1 virus presents a new system for the study of calicivirus biology and species specificity...
  2. pmc Processing map and essential cleavage sites of the nonstructural polyprotein encoded by ORF1 of the feline calicivirus genome
    Stanislav V Sosnovtsev
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892 8007, USA
    J Virol 76:7060-72. 2002
    ..Mutagenesis of two cleavage sites (E(1345)/T(1346) and E(1419)/G(1420)) within the 75.7-kDa Pro-Pol protein previously mapped in bacterial expression studies was not lethal...
  3. pmc Cleavage map and proteolytic processing of the murine norovirus nonstructural polyprotein in infected cells
    Stanislav V Sosnovtsev
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 8007, USA
    J Virol 80:7816-31. 2006
    ..The availability of the MNV nonstructural polyprotein cleavage map in concert with a permissive cell culture system should facilitate studies of norovirus replication...
  4. pmc Feline calicivirus VP2 is essential for the production of infectious virions
    Stanislav V Sosnovtsev
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 50 South Drive MSC8007, Building 50, Room 6316, Bethesda, MD 20892 8007, USA
    J Virol 79:4012-24. 2005
    ....
  5. ncbi request reprint Identification and genomic mapping of the ORF3 and VPg proteins in feline calicivirus virions
    S V Sosnovtsev
    Laboratory of Infectious Diseases, National Institute of Allergies and Infectious Diseases, Bethesda, Maryland, 20892, USA
    Virology 277:193-203. 2000
    ....
  6. ncbi request reprint Feline calicivirus replication induces apoptosis in cultured cells
    Stanislav V Sosnovtsev
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 50 South Drive MSC8007, Building 50, Room 6316, Bethesda, MD 20892 8007, USA
    Virus Res 94:1-10. 2003
    ....
  7. pmc Reverse genetics system for porcine enteric calicivirus, a prototype sapovirus in the Caliciviridae
    Kyeong Ok Chang
    Laboratory of Infectious Diseases, National Institutes of Health DHHS, NIAID LID, Bldg 50, Room 6316, 9000 Rockville Pike, Bethesda, MD 20892 8026, USA
    J Virol 79:1409-16. 2005
    ..This reverse genetics system for PEC provides a new tool to study the molecular basis of replication and pathogenesis for caliciviruses associated with diarrheal disease...
  8. doi request reprint Mapping and modeling of a strain-specific epitope in the Norwalk virus capsid inner shell
    Gabriel I Parra
    Caliciviruses Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    Virology 492:232-41. 2016
    ..The S domain, like the P domain, contains strain-specific epitopes that contribute to the antigenic diversity among the noroviruses. ..
  9. pmc The feline calicivirus leader of the capsid protein is associated with cytopathic effect
    Eugenio J Abente
    Laboratory of Infectious Diseases, NIAID, NIH, Bethesda, MD, USA
    J Virol 87:3003-17. 2013
    ..The host cellular protein annexin A2 was identified as a binding partner of the LC protein, consistent with a role for the LC in mediating host cell interactions that alter the integrity of the cell and enable virus spread...
  10. pmc Diversity of murine norovirus strains isolated from asymptomatic mice of different genetic backgrounds within a single U.S. research institute
    Elyssa L Barron
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America
    PLoS ONE 6:e21435. 2011
    ..Our study indicates that the murine noroviruses are widespread in these animal facilities, despite rigorous guidelines for animal care and maintenance...
  11. pmc Development of Norwalk virus-specific monoclonal antibodies with therapeutic potential for the treatment of Norwalk virus gastroenteritis
    Zhaochun Chen
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    J Virol 87:9547-57. 2013
    ..Because chimpanzee immunoglobulins are virtually identical to human immunoglobulins, these chimpanzee anticapsid MAbs may have a clinical application. ..
  12. pmc Multiple antigenic sites are involved in blocking the interaction of GII.4 norovirus capsid with ABH histo-blood group antigens
    Gabriel I Parra
    Caliciviruses Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, DHHS, Bethesda, Maryland, USA
    J Virol 86:7414-26. 2012
    ....
  13. pmc Nucleotidylylation of the VPg protein of a human norovirus by its proteinase-polymerase precursor protein
    Gaël Belliot
    National Institutes of Health DHHS, NIAID LID, Building 50, Room 6316, 9000 Rockville Pike, Bethesda, MD 20892 8007, USA
    Virology 374:33-49. 2008
    ..Furthermore, evidence was found for the presence of an RNA element near the 3'-end of the polyadenylated genome that enhanced the efficiency of nucleotidylylation in the presence of Mg2+...
  14. pmc Evolutionary dynamics of GII.4 noroviruses over a 34-year period
    Karin Bok
    Norovirus Gastroenteritis Unit, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    J Virol 83:11890-901. 2009
    ..Our analysis of archival GII.4 norovirus strains suggests that this genotype has been circulating for more than three decades and provides new ancestral strain sequences for the analysis of GII.4 evolution...
  15. pmc Genetic characterization of a reptilian calicivirus (Cro1)
    Carlos Sandoval-Jaime
    Caliciviruses Section LID NIAID NIH, Bethesda, MD 20892, USA
    Virol J 9:297. 2012
    ..The goal of this study was to characterize the Cro1 strain 780032I that was isolated in cell culture from a rock rattlesnake (Crotalus lepidus) in the original outbreak...
  16. pmc Bile acids are essential for porcine enteric calicivirus replication in association with down-regulation of signal transducer and activator of transcription 1
    Kyeong Ok Chang
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, 50 South Drive, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 101:8733-8. 2004
    ....
  17. pmc Mutagenesis of tyrosine 24 in the VPg protein is lethal for feline calicivirus
    Tanaji Mitra
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    J Virol 78:4931-5. 2004
    ....
  18. pmc Visualization of feline calicivirus replication in real-time with recombinant viruses engineered to express fluorescent reporter proteins
    Eugenio J Abente
    Laboratory of Infectious Diseases, NIAID, NIH, Bethesda, MD 20892, USA
    Virology 400:18-31. 2010
    ....
  19. ncbi request reprint Pathology of immunodeficient mice with naturally occurring murine norovirus infection
    Jerrold M Ward
    Infectious Disease Pathogenesis Section, Comparative Medicine Branch, Division of Intramural Research, NIAID, NIH, Twinbrook III, Bethesda, Maryland 20892 8135, USA
    Toxicol Pathol 34:708-15. 2006
    ..Further studies are needed to determine whether MNV presents a confounding variable in immunological, toxicological and pathological studies in mice naturally infected with MNV...
  20. pmc In vitro proteolytic processing of the MD145 norovirus ORF1 nonstructural polyprotein yields stable precursors and products similar to those detected in calicivirus-infected cells
    Gaël Belliot
    Laboratory of Infectious Diseases Research Technologies Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892 8026, USA
    J Virol 77:10957-74. 2003
    ..Taken together, our data establish a model for proteolytic processing in the noroviruses that is consistent with nonstructural precursors and products identified in studies of caliciviruses that replicate in cell culture systems...
  21. pmc Isolation of enzymatically active replication complexes from feline calicivirus-infected cells
    Kim Y Green
    National Institutes of Health, Bethesda, Maryland 20892, USA
    J Virol 76:8582-95. 2002
    ..The isolation of enzymatically active RCs containing both viral and cellular proteins should facilitate efforts to dissect the contributions of the virus and the host to FCV RNA replication...
  22. doi request reprint Genetic characterization of feline calicivirus strains associated with varying disease manifestations during an outbreak season in Missouri (1995-1996)
    Victor G Prikhodko
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 50 South Drive MSC8007, Building 50, Room 6316, Bethesda, MD, 20892 8007, USA
    Virus Genes 48:96-110. 2014
    ..We show that genetically distinct FCV strains were cocirculating in the area, and no apparent correlation could be made between overall sequence and observed disease...
  23. ncbi request reprint Naturally occurring murine norovirus infection in a large research institution
    Kathy A Perdue
    Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    J Am Assoc Lab Anim Sci 46:39-45. 2007
    ..Histopathologic lesions consisted only of a few hepatic inflammatory foci in each liver section, some of which were immunoreactive with antibodies to MNV. MNV viral antigens also were present in the mesenteric lymph nodes...
  24. pmc Norovirus proteinase-polymerase and polymerase are both active forms of RNA-dependent RNA polymerase
    Gaël Belliot
    National Institutes of Health DHHS, NIAID LID, Building 50, Room 6316, 9000 Rockville Pike, Bethesda, MD 20892 8007, USA
    J Virol 79:2393-403. 2005
    ..The availability of this recombinant ProPol enzyme might prove useful in the development of antiviral drugs for control of the noroviruses associated with acute gastroenteritis...
  25. pmc Norwalk virus N-terminal nonstructural protein is associated with disassembly of the Golgi complex in transfected cells
    Virneliz Fernandez-Vega
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Virol 78:4827-37. 2004
    ....
  26. pmc Immunogenicity and specificity of norovirus Consensus GII.4 virus-like particles in monovalent and bivalent vaccine formulations
    Gabriel I Parra
    Caliciviruses Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, DHHS, Bethesda, MD 20892, USA
    Vaccine 30:3580-6. 2012
    ....
  27. pmc Chimpanzees as an animal model for human norovirus infection and vaccine development
    Karin Bok
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 108:325-30. 2011
    ..This study establishes the chimpanzee as a viable animal model for the study of norovirus replication and immunity, and shows that NV VLP vaccines could induce protective homologous immunity even after extended periods of time...
  28. pmc Apoptosis in murine norovirus-infected RAW264.7 cells is associated with downregulation of survivin
    Karin Bok
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 50 South Drive, Bldg 50, Room 6316, Bethesda, MD 20892, USA
    J Virol 83:3647-56. 2009
    ..We observed that MNV-1 replication in RAW264.7 cells activated caspases, resulting in apoptosis through the mitochondrial pathway, possibly as a result of downregulation of survivin...
  29. pmc Static and Evolving Norovirus Genotypes: Implications for Epidemiology and Immunity
    Gabriel I Parra
    Caliciviruses Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America
    PLoS Pathog 13:e1006136. 2017
    ..We propose that "immunotypes" and their evolutionary patterns influence the prevalence of a particular norovirus genotype in the human population...
  30. pmc Recovery of murine norovirus and feline calicivirus from plasmids encoding EMCV IRES in stable cell lines expressing T7 polymerase
    Carlos Sandoval-Jaime
    Caliciviruses Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, DHHS, Bethesda, MD, USA
    J Virol Methods 217:1-7. 2015
    ..The strategy worked also for the efficient recovery of feline calicivirus in these normally nonpermissive cell types. This simplified reverse genetics approach may be broadly applicable to other caliciviruses. ..