Carl F Schaefer
Affiliation: National Institutes of Health
- The cancer genome anatomy project: online resources to reveal the molecular signatures of cancerRobert L Strausberg
National Cancer Institute, Bethesda, MD 20892, USA
Cancer Invest 20:1038-50. 2002
- Pathway databasesCarl F Schaefer
Center for Bioinformatics, National Cancer Institute, National Institutes of Health, 6116 Executive Boulevard, Suite 403, Rockville, MD 20852, USA
Ann N Y Acad Sci 1020:77-91. 2004..Computable representations of pathways provide a basis for various analyses, including detection of broad network patterns, comparison with mRNA or protein abundance, and simulation...
- Identification of microbial DNA in human cancerChristopher G Duncan
Preston Robert Tisch Brain Tumor Center, Pediatric Brain Tumor Foundation Institute, Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA
BMC Med Genomics 2:22. 2009..CONCLUSION: DK-MICROBE can identify previously unknown infectious agents in human tumors, and is now available for further applications for the identification of pathogen DNA in human cancer and other diseases...
- PID: the Pathway Interaction DatabaseCarl F Schaefer
National Cancer Institute, Center for Biomedical Informatics and Information Technology, Rockville MD, USA
Nucleic Acids Res 37:D674-9. 2009..The database is updated with new pathway content every month and supplemented by specially commissioned articles on the practical uses of other relevant online tools...
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequencesRobert L Strausberg
National Cancer Institute, Bethessda, MD 20892 2580, USA
Proc Natl Acad Sci U S A 99:16899-903. 2002..All MGC sequences and clones are available without restriction through public databases and clone distribution networks (see http:mgc.nci.nih.gov)...
- Cancers as wounds that do not heal: differences and similarities between renal regeneration/repair and renal cell carcinomaJoseph Riss
Laboratory of Biosystems and Cancer, Comparative Oncology Program, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
Cancer Res 66:7216-24. 2006..The observations reported here provide a conceptual framework for further efforts to understand the biology and to develop more effective diagnostic biomarkers and therapeutic strategies for renal tumors and renal ischemia...
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)Daniela S Gerhard
Genome Res 14:2121-7. 2004..Recently, a rat cDNA component was added to the project, and ongoing frog (Xenopus) and zebrafish (Danio) cDNA projects were expanded to take advantage of the high-throughput MGC pipeline...
- An anatomy of normal and malignant gene expressionKathy Boon
Duke University Medical Center, Durham, NC 27710, USA
Proc Natl Acad Sci U S A 99:11287-92. 2002..We report here an easily accessible view of nearly any gene's expression in a wide variety of malignant and normal tissues...