Alan Lap Yin Pang

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Expression of human NAA11 (ARD1B) gene is tissue-specific and is regulated by DNA methylation
    Alan L Y Pang
    Section on Clinical and Developmental Genomics, Eunice Kennedy Shriver National Institute of Child Health and Human Development National Institutes of Health, Bethesda, MD, USA
    Epigenetics 6:1391-9. 2011
  2. pmc Cloning, characterization, and expression analysis of the novel acetyltransferase retrogene Ard1b in the mouse
    Alan Lap Yin Pang
    Laboratory of Clinical Genomics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    Biol Reprod 81:302-9. 2009
  3. doi request reprint Biochemical characterization of a testis-predominant isoform of N-alpha acetyltransferase
    Alan Lap Yin Pang
    Section on Clinical Genomics, Laboratory of Clinical and Developmental Genomics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
    Methods Mol Biol 825:93-104. 2012
  4. ncbi request reprint Expression profiling of purified male germ cells: stage-specific expression patterns related to meiosis and postmeiotic development
    Alan L Y Pang
    Laboratory of Clinical Genomics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 4429, USA
    Physiol Genomics 24:75-85. 2006
  5. ncbi request reprint Analysis of mouse germ-cell transcriptome at different stages of spermatogenesis by SAGE: biological significance
    Shao Ming Wu
    Laboratory of Clinical Genomics, NICHD, National Institutes of Health, Bethesda, MD 20892, USA
    Genomics 84:971-81. 2004
  6. pmc Genomic landscape of developing male germ cells
    Tin Lap Lee
    Section on Developmental Genomics, Laboratory of Clinical Genomics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 4429, USA
    Birth Defects Res C Embryo Today 87:43-63. 2009
  7. ncbi request reprint Identification of differentially expressed genes in mouse spermatogenesis
    Alan L Y Pang
    Section on Developmental Genomics, Laboratory of Clinical Genomics, National Institute of Child Health and Human Development, NIH, USA
    J Androl 24:899-911. 2003
  8. pmc Up-regulation of proliferative and migratory genes in regulatory T cells from patients with metastatic castration-resistant prostate cancer
    Ngar Yee Huen
    Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Int J Cancer 133:373-82. 2013
  9. pmc Idiopathic Autism: Cellular and Molecular Phenotypes in Pluripotent Stem Cell-Derived Neurons
    Xiaozhuo Liu
    Laboratory of Clinical and Developmental Genomics, National Institute of Child Health and Human Development NICHD, National Institutes of Health NIH, 10 Center Drive, MSC 1255, Building 10, Room 1C 250, Bethesda, MD, 20892 1255, USA
    Mol Neurobiol . 2016
  10. ncbi request reprint Metastasis-associated gene expression profile of liver and subcutaneous lesions derived from mouse pheochromocytoma cells
    Shoichiro Ohta
    Reproductive Biology and Medicine Branch, National Institute of Child Health and Human Development, Bethesda, Maryland 20892 1109, USA
    Mol Carcinog 47:245-51. 2008

Collaborators

  • Wai Yee Chan
  • Tin Lap Lee
  • Hoi Hung Cheung
  • Mark N Ziats
  • Ravi A Madan
  • Graeme Eisenhofer
  • Yan A Su
  • Arthur Tischler
  • J F Powers
  • Owen M Rennert
  • Shoichiro Ohta
  • Xiaozhuo Liu
  • Ngar Yee Huen
  • Vanessa Baxendale
  • Karel Pacak
  • Edwin W Lai
  • Angele Nalbandian
  • Neelakanta Ravindranath
  • Shao Ming Wu
  • Lucile Canterel-Thouennon
  • Lu Yang
  • Margarita Raygada
  • Susan Swedo
  • Kwok Pui Fung
  • Audrey Thurm
  • Emilie Campanac
  • Dax A Hoffman
  • James L Gulley
  • Chiara Intrivici
  • Jo A Tucker
  • Kwong Y Tsang
  • Vittore Cereda
  • Matteo Vergati
  • Jeffrey Schlom
  • Caroline Jochems
  • John C Morris
  • Shun Ichiro Taniguchi
  • Jeffery E Green
  • Richard Zhang
  • Paul Sirajuddin
  • Morihiro Watanabe
  • Hiroshi Yazawa
  • Robert A Wesley
  • Pavel Blazicek
  • Daniel Djakiew
  • Lucia Ksinantova
  • Jan Breza
  • Ronald de Krijger
  • Richard Kvetnansky
  • Frederieke M Brouwers
  • Timothy Stitely
  • Yali Chen
  • Peter J Munson
  • Michael Yiu Kwong Leung
  • Martin Dym

Detail Information

Publications12

  1. pmc Expression of human NAA11 (ARD1B) gene is tissue-specific and is regulated by DNA methylation
    Alan L Y Pang
    Section on Clinical and Developmental Genomics, Eunice Kennedy Shriver National Institute of Child Health and Human Development National Institutes of Health, Bethesda, MD, USA
    Epigenetics 6:1391-9. 2011
    ..Taken together, our results indicate NAA11 expression is tissue-specific and is epigenetically regulated by DNA methylation...
  2. pmc Cloning, characterization, and expression analysis of the novel acetyltransferase retrogene Ard1b in the mouse
    Alan Lap Yin Pang
    Laboratory of Clinical Genomics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    Biol Reprod 81:302-9. 2009
    ..Our results suggest that ARD1B may have an important role in the later course of the spermatogenic process...
  3. doi request reprint Biochemical characterization of a testis-predominant isoform of N-alpha acetyltransferase
    Alan Lap Yin Pang
    Section on Clinical Genomics, Laboratory of Clinical and Developmental Genomics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
    Methods Mol Biol 825:93-104. 2012
    ....
  4. ncbi request reprint Expression profiling of purified male germ cells: stage-specific expression patterns related to meiosis and postmeiotic development
    Alan L Y Pang
    Laboratory of Clinical Genomics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 4429, USA
    Physiol Genomics 24:75-85. 2006
    ..We also provide evidence that underscores the advantage of using purified germ cells over whole testes in profiling spermatogenic gene expression to identify transcripts that demonstrate stage-specific expression patterns...
  5. ncbi request reprint Analysis of mouse germ-cell transcriptome at different stages of spermatogenesis by SAGE: biological significance
    Shao Ming Wu
    Laboratory of Clinical Genomics, NICHD, National Institutes of Health, Bethesda, MD 20892, USA
    Genomics 84:971-81. 2004
    ..The databases generated by this work provide very useful resources for cellular localization of genes in silico. They are also extremely useful as sources for identification of splice variants of genes in germ cells...
  6. pmc Genomic landscape of developing male germ cells
    Tin Lap Lee
    Section on Developmental Genomics, Laboratory of Clinical Genomics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 4429, USA
    Birth Defects Res C Embryo Today 87:43-63. 2009
    ..It is anticipated that application of systems biology approaches will further our understanding of the regulatory mechanism of spermatogenesis...
  7. ncbi request reprint Identification of differentially expressed genes in mouse spermatogenesis
    Alan L Y Pang
    Section on Developmental Genomics, Laboratory of Clinical Genomics, National Institute of Child Health and Human Development, NIH, USA
    J Androl 24:899-911. 2003
    ..Many of the genes identified were not previously characterized. This study highlights new targets for manipulation to unravel the molecular mechanism of spermatogenesis...
  8. pmc Up-regulation of proliferative and migratory genes in regulatory T cells from patients with metastatic castration-resistant prostate cancer
    Ngar Yee Huen
    Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Int J Cancer 133:373-82. 2013
    ..Results also suggest that the alterations observed in gene expression profiles of Tregs in mCRPC patients may be part of the mechanism of tumor escape from host immune surveillance...
  9. pmc Idiopathic Autism: Cellular and Molecular Phenotypes in Pluripotent Stem Cell-Derived Neurons
    Xiaozhuo Liu
    Laboratory of Clinical and Developmental Genomics, National Institute of Child Health and Human Development NICHD, National Institutes of Health NIH, 10 Center Drive, MSC 1255, Building 10, Room 1C 250, Bethesda, MD, 20892 1255, USA
    Mol Neurobiol . 2016
    ..Our data demonstrate aberrant voltage-gated currents and underlying molecular changes related to synaptic function in iPSC-derived neurons from individuals with idiopathic autism as compared to unaffected siblings controls...
  10. ncbi request reprint Metastasis-associated gene expression profile of liver and subcutaneous lesions derived from mouse pheochromocytoma cells
    Shoichiro Ohta
    Reproductive Biology and Medicine Branch, National Institute of Child Health and Human Development, Bethesda, Maryland 20892 1109, USA
    Mol Carcinog 47:245-51. 2008
    ....
  11. ncbi request reprint Downregulation of metastasis suppressor genes in malignant pheochromocytoma
    Shoichiro Ohta
    Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, Bethesda, MD 20892 1583, USA
    Int J Cancer 114:139-43. 2005
    ..Thus, we conclude that altered function of these metastasis suppressor gene pathways may play an important role in the malignant behavior of pheochromocytoma...
  12. ncbi request reprint A novel function of differentiation revealed by cDNA microarray profiling of p75NTR-regulated gene expression
    Angele Nalbandian
    Department of Cell Biology, Georgetown University Medical Center, Medical Dental Building, Washington, DC 20057 1436, USA
    Differentiation 73:385-96. 2005
    ....