Sanjeewani T Palayoor

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. doi request reprint Fractionated radiation therapy can induce a molecular profile for therapeutic targeting
    Molykutty John-Aryankalayil
    Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Radiat Res 174:446-58. 2010
  2. pmc Differential expression of stress and immune response pathway transcripts and miRNAs in normal human endothelial cells subjected to fractionated or single-dose radiation
    Sanjeewani T Palayoor
    Authors Affiliations Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland and
    Mol Cancer Res 12:1002-15. 2014
  3. pmc Gene expression profile of coronary artery cells treated with nonsteroidal anti-inflammatory drugs reveals off-target effects
    Sanjeewani T Palayoor
    Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, 9000 Rockville Pike, Building 10, Room B3B406, Bethesda, MD 20892, USA
    J Cardiovasc Pharmacol 59:487-99. 2012
  4. ncbi request reprint Effect of radiation and ibuprofen on normoxic renal carcinoma cells overexpressing hypoxia-inducible factors by loss of von Hippel-Lindau tumor suppressor gene function
    Sanjeewani T Palayoor
    Radiation Oncology Branch, Center for Cancer Research and the Molecular Radiation Therapeutics Branch, Division of Cancer and Treatment and Diagnosis, National Cancer Institute, NIH, Bethesda, Maryland, USA
    Clin Cancer Res 10:4158-64. 2004
  5. ncbi request reprint Radiation sensitivity of human carcinoma cells transfected with small interfering RNA targeted against cyclooxygenase-2
    Sanjeewani T Palayoor
    Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892 1002, USA
    Clin Cancer Res 11:6980-6. 2005
  6. pmc PX-478, an inhibitor of hypoxia-inducible factor-1alpha, enhances radiosensitivity of prostate carcinoma cells
    Sanjeewani T Palayoor
    Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Int J Cancer 123:2430-7. 2008
  7. pmc NS-398, ibuprofen, and cyclooxygenase-2 RNA interference produce significantly different gene expression profiles in prostate cancer cells
    Molykutty John-Aryankalayil
    Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, 9000 Rockville Pike, Room B3 B 406, Building 10, Bethesda, MD 20892, USA
    Mol Cancer Ther 8:261-73. 2009
  8. ncbi request reprint Ibuprofen-mediated reduction of hypoxia-inducible factors HIF-1alpha and HIF-2alpha in prostate cancer cells
    Sanjeewani T Palayoor
    Radiation Oncology Branch, Center for Cancer Research and the Molecular Radiation Therapeutics Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, NIH, Bethesda, Maryland, 20892 1002, USA
    Clin Cancer Res 9:3150-7. 2003
  9. pmc Fractionated radiation alters oncomir and tumor suppressor miRNAs in human prostate cancer cells
    Molykutty John-Aryankalayil
    Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Radiat Res 178:105-17. 2012
  10. pmc Radiation survivors: understanding and exploiting the phenotype following fractionated radiation therapy
    Adeola Y Makinde
    National Institutes of Health National Cancer Institute, 9000 Rockville Pike, Bldg 10, B3B406, Bethesda, MD 20892, USA
    Mol Cancer Res 11:5-12. 2013

Collaborators

Detail Information

Publications11

  1. doi request reprint Fractionated radiation therapy can induce a molecular profile for therapeutic targeting
    Molykutty John-Aryankalayil
    Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Radiat Res 174:446-58. 2010
    ..This study suggests that fractionated radiation may be a uniquely exploitable, non-oncogene-addiction stress pathway for molecular therapeutic targeting...
  2. pmc Differential expression of stress and immune response pathway transcripts and miRNAs in normal human endothelial cells subjected to fractionated or single-dose radiation
    Sanjeewani T Palayoor
    Authors Affiliations Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland and
    Mol Cancer Res 12:1002-15. 2014
    ..In addition, mRNAs and miRs associated with DNA replication, recombination and repair, apoptosis, cardiovascular events, and angiogenesis were revealed...
  3. pmc Gene expression profile of coronary artery cells treated with nonsteroidal anti-inflammatory drugs reveals off-target effects
    Sanjeewani T Palayoor
    Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, 9000 Rockville Pike, Building 10, Room B3B406, Bethesda, MD 20892, USA
    J Cardiovasc Pharmacol 59:487-99. 2012
    ....
  4. ncbi request reprint Effect of radiation and ibuprofen on normoxic renal carcinoma cells overexpressing hypoxia-inducible factors by loss of von Hippel-Lindau tumor suppressor gene function
    Sanjeewani T Palayoor
    Radiation Oncology Branch, Center for Cancer Research and the Molecular Radiation Therapeutics Branch, Division of Cancer and Treatment and Diagnosis, National Cancer Institute, NIH, Bethesda, Maryland, USA
    Clin Cancer Res 10:4158-64. 2004
    ..The purpose of the present study was to investigate the impact of HIFs on radiosensitivity...
  5. ncbi request reprint Radiation sensitivity of human carcinoma cells transfected with small interfering RNA targeted against cyclooxygenase-2
    Sanjeewani T Palayoor
    Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892 1002, USA
    Clin Cancer Res 11:6980-6. 2005
    ..However, the precise role of COX-2 in radiation response is not clear. The purpose of the present study was to investigate the in vitro radiosensitivity of tumor cells as a function of COX-2 expression...
  6. pmc PX-478, an inhibitor of hypoxia-inducible factor-1alpha, enhances radiosensitivity of prostate carcinoma cells
    Sanjeewani T Palayoor
    Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Int J Cancer 123:2430-7. 2008
    ..Although the precise mechanism of enhancement of radiosensitivity remains to be identified, this study suggests a potential role for PX-478 as a clinical radiation enhancer...
  7. pmc NS-398, ibuprofen, and cyclooxygenase-2 RNA interference produce significantly different gene expression profiles in prostate cancer cells
    Molykutty John-Aryankalayil
    Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, 9000 Rockville Pike, Room B3 B 406, Building 10, Bethesda, MD 20892, USA
    Mol Cancer Ther 8:261-73. 2009
    ....
  8. ncbi request reprint Ibuprofen-mediated reduction of hypoxia-inducible factors HIF-1alpha and HIF-2alpha in prostate cancer cells
    Sanjeewani T Palayoor
    Radiation Oncology Branch, Center for Cancer Research and the Molecular Radiation Therapeutics Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, NIH, Bethesda, Maryland, 20892 1002, USA
    Clin Cancer Res 9:3150-7. 2003
    ..HIF-regulated proteins, vascular endothelial growth factor (VEGF) and glucose transporter-1 (Glut-1), were analyzed by ELISA and Western blot analysis, respectively...
  9. pmc Fractionated radiation alters oncomir and tumor suppressor miRNAs in human prostate cancer cells
    Molykutty John-Aryankalayil
    Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Radiat Res 178:105-17. 2012
    ..Our data support the potential for using fractionated radiation to induce molecular targets and radiation-induced miRNAs may have a significant role in predicting radiosensitivity...
  10. pmc Radiation survivors: understanding and exploiting the phenotype following fractionated radiation therapy
    Adeola Y Makinde
    National Institutes of Health National Cancer Institute, 9000 Rockville Pike, Bldg 10, B3B406, Bethesda, MD 20892, USA
    Mol Cancer Res 11:5-12. 2013
    ..Given that more normal tissue is treated, albeit to lower doses with these newer techniques, the response of the normal tissue may also influence long-term treatment outcome...
  11. pmc Defining molecular signature of pro-immunogenic radiotherapy targets in human prostate cancer cells
    Molykutty J Aryankalayil
    a Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland
    Radiat Res 182:139-48. 2014
    ..The findings of this study together with the gene expression data suggest that cells subjected to multifractionated radiation treatment would promote productive immune cell-tumor cell interactions. ..