Adrian B McDermott

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. doi request reprint CD8(+) T cells in preventing HIV infection and disease
    Adrian B McDermott
    Immunology Laboratory, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    AIDS 26:1281-92. 2012
  2. pmc HIV vaccine research and discovery in the nonhuman primates model: a unified theory in acquisition prevention and control of SIV infection
    Rebecca M Lynch
    Vaccine Research Center, NIAID, NIH, Bethesda, MD 20892, USA
    Curr Opin HIV AIDS 8:288-94. 2013
  3. pmc Virus inhibition activity of effector memory CD8(+) T cells determines simian immunodeficiency virus load in vaccinated monkeys after vaccine breakthrough infection
    Takuya Yamamoto
    Vaccine Research Center, NIAID, NIH, Bethesda, Maryland, USA
    J Virol 86:5877-84. 2012
  4. doi request reprint Quality and quantity of TFH cells are critical for broad antibody development in SHIVAD8 infection
    Takuya Yamamoto
    Immunology Laboratory, Vaccine Research Center, National Institute of Allergy and Infectious Diseases NIAID, National Institutes of Health NIH, Bethesda, MD 20892, USA
    Sci Transl Med 7:298ra120. 2015
  5. pmc Homologous boosting with adenoviral serotype 5 HIV vaccine (rAd5) vector can boost antibody responses despite preexisting vector-specific immunity in a randomized phase I clinical trial
    Uzma N Sarwar
    Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America
    PLoS ONE 9:e106240. 2014
  6. pmc Immunogenicity of a Prefusion HIV-1 Envelope Trimer in Complex with a Quaternary-Structure-Specific Antibody
    Cheng Cheng
    Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    J Virol 90:2740-55. 2015

Collaborators

Detail Information

Publications6

  1. doi request reprint CD8(+) T cells in preventing HIV infection and disease
    Adrian B McDermott
    Immunology Laboratory, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    AIDS 26:1281-92. 2012
    ..In the context of previous clinical HIV/AIDS vaccine trials, we consider the challenges faced by therapeutic and vaccine strategies designed to elicit effective HIV-specific CD8 T cells...
  2. pmc HIV vaccine research and discovery in the nonhuman primates model: a unified theory in acquisition prevention and control of SIV infection
    Rebecca M Lynch
    Vaccine Research Center, NIAID, NIH, Bethesda, MD 20892, USA
    Curr Opin HIV AIDS 8:288-94. 2013
    ....
  3. pmc Virus inhibition activity of effector memory CD8(+) T cells determines simian immunodeficiency virus load in vaccinated monkeys after vaccine breakthrough infection
    Takuya Yamamoto
    Vaccine Research Center, NIAID, NIH, Bethesda, Maryland, USA
    J Virol 86:5877-84. 2012
    ..The ability to elicit such virus-specific EM CD8(+) T cells might contribute substantially to an efficacious HIV/AIDS vaccine, even after breakthrough infection...
  4. doi request reprint Quality and quantity of TFH cells are critical for broad antibody development in SHIVAD8 infection
    Takuya Yamamoto
    Immunology Laboratory, Vaccine Research Center, National Institute of Allergy and Infectious Diseases NIAID, National Institutes of Health NIH, Bethesda, MD 20892, USA
    Sci Transl Med 7:298ra120. 2015
    ..These studies highlight the importance of boosting high-quality TFH populations as part of a robust vaccine regimen aimed at eliciting bNabs. ..
  5. pmc Homologous boosting with adenoviral serotype 5 HIV vaccine (rAd5) vector can boost antibody responses despite preexisting vector-specific immunity in a randomized phase I clinical trial
    Uzma N Sarwar
    Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America
    PLoS ONE 9:e106240. 2014
    ..Needle-free delivery improves the immunogenicity of DNA vaccines but is also associated with more local reactogenicity. Here we report the first comparison of Biojector and needle administration of a candidate rAd5 HIV vaccine...
  6. pmc Immunogenicity of a Prefusion HIV-1 Envelope Trimer in Complex with a Quaternary-Structure-Specific Antibody
    Cheng Cheng
    Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    J Virol 90:2740-55. 2015
    ..These data suggest that appropriate modifications of trimer immunogens could further focus the immune response on key neutralization epitopes...