Marcello Maggio

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Association between hormones and metabolic syndrome in older Italian men
    Marcello Maggio
    Clinical Research Branch, National Institute on Aging, Baltimore, Maryland 21225, USA
    J Am Geriatr Soc 54:1832-8. 2006
  2. pmc Usefulness of uric acid to predict changes in C-reactive protein and interleukin-6 in 3-year period in Italians aged 21 to 98 years
    Carmelinda Ruggiero
    Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA
    Am J Cardiol 100:115-21. 2007
  3. pmc Relationship between low levels of anabolic hormones and 6-year mortality in older men: the aging in the Chianti Area (InCHIANTI) study
    Marcello Maggio
    National Institute on Aging, National Institutes of Health, NIA Clinical Research Branch at Harbor Hospital, 3001 S Hanover Street, Baltimore, MD 21225, USA
    Arch Intern Med 167:2249-54. 2007
  4. pmc Low testosterone levels and the risk of anemia in older men and women
    Luigi Ferrucci
    Clinical Research Branch, Longitudinal Studies Section, National Institute on Aging, Baltimore, MD 21225, USA
    Arch Intern Med 166:1380-8. 2006
  5. pmc Association of hormonal dysregulation with metabolic syndrome in older women: data from the InCHIANTI study
    Marcello Maggio
    National Institute on Aging, NIH, NIA ASTRA Unit at Harbor Hospital, 3001 S Hanover St, Baltimore, MD 21225, USA
    Am J Physiol Endocrinol Metab 292:E353-8. 2007
  6. pmc Relation of angiotensin-converting enzyme inhibitor treatment to insulin-like growth factor-1 serum levels in subjects >65 years of age (the InCHIANTI study)
    Marcello Maggio
    Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Intramural Research Program, National Institutes of Health, Bethesda, Maryland, USA
    Am J Cardiol 97:1525-9. 2006
  7. pmc High-dose isoflavones do not improve metabolic and inflammatory parameters in androgen-deprived men with prostate cancer
    Joshua K Napora
    National Institute of Health, National Institute on Aging, Laboratory of Clinical Investigation, Diabetes Section, Baltimore, Maryland, USA
    J Androl 32:40-8. 2011
  8. pmc Adipocytokines and the metabolic syndrome among older persons with and without obesity: the InCHIANTI study
    Sari Stenholm
    Clinical Research Branch, National Institute on Aging, 3001 S Hanover Street, Baltimore, MD 21225, USA
    Clin Endocrinol (Oxf) 73:55-65. 2010
  9. pmc White blood cell count and mortality in the Baltimore Longitudinal Study of Aging
    Carmelinda Ruggiero
    Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21225, USA
    J Am Coll Cardiol 49:1841-50. 2007
  10. pmc The interplay between uric acid and antioxidants in relation to physical function in older persons
    Carmelinda Ruggiero
    Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21225, USA
    J Am Geriatr Soc 55:1206-15. 2007

Detail Information

Publications26

  1. pmc Association between hormones and metabolic syndrome in older Italian men
    Marcello Maggio
    Clinical Research Branch, National Institute on Aging, Baltimore, Maryland 21225, USA
    J Am Geriatr Soc 54:1832-8. 2006
    ....
  2. pmc Usefulness of uric acid to predict changes in C-reactive protein and interleukin-6 in 3-year period in Italians aged 21 to 98 years
    Carmelinda Ruggiero
    Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA
    Am J Cardiol 100:115-21. 2007
    ..In conclusion, our study suggests that in a population-based cohort, baseline UA and changes in circulating UA during 3 years of follow-up predict changes in circulating CRP independent of relevant confounders, including baseline IL-6...
  3. pmc Relationship between low levels of anabolic hormones and 6-year mortality in older men: the aging in the Chianti Area (InCHIANTI) study
    Marcello Maggio
    National Institute on Aging, National Institutes of Health, NIA Clinical Research Branch at Harbor Hospital, 3001 S Hanover Street, Baltimore, MD 21225, USA
    Arch Intern Med 167:2249-54. 2007
    ..We hypothesized that in older men a parallel age-associated decline in bioavailable testosterone, IGF-1, and DHEA-S secretion is associated with higher mortality independent of potential confounders...
  4. pmc Low testosterone levels and the risk of anemia in older men and women
    Luigi Ferrucci
    Clinical Research Branch, Longitudinal Studies Section, National Institute on Aging, Baltimore, MD 21225, USA
    Arch Intern Med 166:1380-8. 2006
    ..Anemia is a frequent feature of male hypogonadism and anti-androgenic treatment. We hypothesized that the presence of low testosterone levels in older persons is a risk factor for anemia...
  5. pmc Association of hormonal dysregulation with metabolic syndrome in older women: data from the InCHIANTI study
    Marcello Maggio
    National Institute on Aging, NIH, NIA ASTRA Unit at Harbor Hospital, 3001 S Hanover St, Baltimore, MD 21225, USA
    Am J Physiol Endocrinol Metab 292:E353-8. 2007
    ..Further studies are needed to support the notion that raising SHBG is a potential therapeutic target for prevention and treatment of MetS...
  6. pmc Relation of angiotensin-converting enzyme inhibitor treatment to insulin-like growth factor-1 serum levels in subjects >65 years of age (the InCHIANTI study)
    Marcello Maggio
    Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Intramural Research Program, National Institutes of Health, Bethesda, Maryland, USA
    Am J Cardiol 97:1525-9. 2006
    ..This may be 1 of the mechanisms by which ACE inhibitors might slow the decreases in muscle strength and physical function that are often observed in older subjects...
  7. pmc High-dose isoflavones do not improve metabolic and inflammatory parameters in androgen-deprived men with prostate cancer
    Joshua K Napora
    National Institute of Health, National Institute on Aging, Laboratory of Clinical Investigation, Diabetes Section, Baltimore, Maryland, USA
    J Androl 32:40-8. 2011
    ..We found that high-dose isoflavones over a course of 12 weeks do not improve metabolic or inflammatory parameters in androgen-deprived men...
  8. pmc Adipocytokines and the metabolic syndrome among older persons with and without obesity: the InCHIANTI study
    Sari Stenholm
    Clinical Research Branch, National Institute on Aging, 3001 S Hanover Street, Baltimore, MD 21225, USA
    Clin Endocrinol (Oxf) 73:55-65. 2010
    ..The purpose of this study was to: (1) examine the role of adipocytokines in the association between obesity and the MetS and (2) to determine whether the association is different in obese and non-obese persons...
  9. pmc White blood cell count and mortality in the Baltimore Longitudinal Study of Aging
    Carmelinda Ruggiero
    Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21225, USA
    J Am Coll Cardiol 49:1841-50. 2007
    ..We investigated the secular trend in white blood cell (WBC) count and the relationship between WBC count and mortality between 1958 and 2002...
  10. pmc The interplay between uric acid and antioxidants in relation to physical function in older persons
    Carmelinda Ruggiero
    Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21225, USA
    J Am Geriatr Soc 55:1206-15. 2007
    ..To investigate the relationship between circulating uric acid (UA) levels and plasma antioxidants and whether antioxidant levels modulate the association between UA and physical function...
  11. ncbi request reprint Aging, androgens, and the metabolic syndrome in a longitudinal study of aging
    Annabelle Rodriguez
    Department of Medicine, Division of Endocrinology, Johns Hopkins Bayview Medical Center, B Building, Suite 114, 4940 Eastern Avenue, Baltimore, Maryland 21224, USA
    J Clin Endocrinol Metab 92:3568-72. 2007
    ..The aim of this study was to evaluate the relationship between the MS and circulating androgen levels in a cohort of men in the Baltimore Longitudinal Study of Aging...
  12. pmc Anabolic and catabolic biomarkers as predictors of muscle strength decline: the InCHIANTI study
    Sari Stenholm
    National Institute on Aging, Clinical Research Branch, Longitudinal Studies Section, Baltimore, Maryland 21225, USA
    Rejuvenation Res 13:3-11. 2010
    ..This study aims to examine whether high levels of multiple catabolic and low levels of multiple anabolic biomarkers predict accelerated decline of muscle strength...
  13. pmc Uric acid and inflammatory markers
    Carmelinda Ruggiero
    Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, NIH, Baltimore, MD, USA
    Eur Heart J 27:1174-81. 2006
    ..Epidemiological studies have recently shown that UA may be a risk factor for cardiovascular diseases and a negative prognostic marker for mortality in subjects with pre-existing heart failure...
  14. pmc Arterial stiffness and bone demineralization: the Baltimore longitudinal study of aging
    Francesco Giallauria
    Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Baltimore, Maryland, USA
    Am J Hypertens 24:970-5. 2011
    ..The aims of this study were to evaluate whether the association between arterial stiffness and bone demineralization is independent of age, and to explore putative mechanisms that may mediate their relationship...
  15. pmc Arterial stiffness and vitamin D levels: the Baltimore longitudinal study of aging
    Francesco Giallauria
    Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, 3001 South Hanover Street, Baltimore, Maryland 21225, USA
    J Clin Endocrinol Metab 97:3717-23. 2012
    ..The importance of vitamin D for bone health has long been acknowledged. Recent evidence suggests that vitamin D can also play a role in reducing the risk of several other diseases, including cardiovascular disease...
  16. pmc Effects of high-dose isoflavones on metabolic and inflammatory markers in healthy postmenopausal women
    Cornelia Charles
    Laboratory of Clinical Investigation, Diabetes Section, National Institute on Aging, Baltimore, MD, USA
    Menopause 16:395-400. 2009
    ..However, the effect of isoflavones on adipokines/cytokines remains unclear. The purpose of this study was to evaluate the effect of high-dose isoflavones on inflammatory and metabolic markers in postmenopausal women...
  17. ncbi request reprint Correlation between testosterone and the inflammatory marker soluble interleukin-6 receptor in older men
    Marcello Maggio
    Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21225, USA
    J Clin Endocrinol Metab 91:345-7. 2006
    ..An age-associated decline in testosterone (T) levels and an increase in proinflammatory cytokines contribute to chronic diseases in older men. Whether and how these changes are related is unclear...
  18. pmc Glucose and insulin measurements from the oral glucose tolerance test and mortality prediction
    E Jeffrey Metter
    Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21225, USA
    Diabetes Care 31:1026-30. 2008
    ..To verify what information from oral glucose tolerance tests (OGTTs) independently predicts mortality...
  19. pmc Interleukin-6 in aging and chronic disease: a magnificent pathway
    Marcello Maggio
    Clinical Research Branch, Longitudinal Studies Section, National Institute on Aging, National Institutes of Health, Baltimore, MD 21225, USA
    J Gerontol A Biol Sci Med Sci 61:575-84. 2006
    ....
  20. ncbi request reprint Circulating inflammatory cytokine expression in men with prostate cancer undergoing androgen deprivation therapy
    Marcello Maggio
    Longitudinal Studies Section, Clinical Research Branch and the Laboratory of Immunology, National Institutes of Health, National Institute on Aging, Baltimore, MD, USA
    J Androl 27:725-8. 2006
    ..Prospective studies are needed to evaluate for any acute changes in these inflammatory markers that might occur after the initiation of ADT...
  21. pmc Bioavailable Testosterone Linearly Declines Over A Wide Age Spectrum in Men and Women From The Baltimore Longitudinal Study of Aging
    Elisa Fabbri
    Translational Gerontology Branch, Longitudinal Study Section, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland Department of Medical and Surgical Sciences, University of Bologna, Italy
    J Gerontol A Biol Sci Med Sci 71:1202-9. 2016
    ....
  22. pmc Longitudinal changes in BMD and bone geometry in a population-based study
    Fulvio Lauretani
    Tuscany Regional Health Agency, Florence, Italy
    J Bone Miner Res 23:400-8. 2008
    ..Periosteal apposition occurred both in men and women. Endocortical resorption causes bone loss in older women despite periosteal apposition...
  23. ncbi request reprint Use of ACE inhibitors is associated with elevated levels of IGFBP-3 among hypertensive older adults: results from the IlSIRENTE study
    Graziano Onder
    Department of Geriatrics, Catholic University of the Sacred Heart, Rome, Italy
    Eur J Clin Pharmacol 63:389-95. 2007
    ..However, this relationship has only rarely been investigated in humans. The aim of the present cross-sectional study was to assess the association of ACE inhibitors with free IGF-1 and IGFBP-3 in the blood of older hypertensive adults...
  24. pmc Is research on hormones and aging finished? No! Just started!
    Anne R Cappola
    J Gerontol A Biol Sci Med Sci 63:696-7. 2008
  25. ncbi request reprint Decline in insulin-like growth factor-I levels across adult life span in two large population studies
    Marcello Maggio
    J Gerontol A Biol Sci Med Sci 61:182-3. 2006
  26. ncbi request reprint Consensus Document on substitution therapy with DHEA in the elderly
    Giorgio Valenti
    Dipartimento di Medicina Interna e Scienze Biomediche, Sezione Geriatria, Universita degli Studi di Parma, Via Gramsci 14, 43100 Parma, Italy
    Aging Clin Exp Res 18:277-300. 2006