Mary R Lee

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Relationship of plasma oxytocin levels to baseline symptoms and symptom changes during three weeks of daily oxytocin administration in people with schizophrenia
    Mary R Lee
    National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism, Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, Bethesda, MD, United States Electronic address
    Schizophr Res 172:165-8. 2016
  2. pmc Targeting the Oxytocin System to Treat Addictive Disorders: Rationale and Progress to Date
    Mary R Lee
    Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, National Institute on Alcohol Abuse and Alcoholism, and National Institute on Drug Abuse, 10 Center Drive, MSC 1108, Bethesda, MD, 20892 1108, USA
    CNS Drugs 30:109-23. 2016
  3. doi request reprint Complexity of oxytocin׳s effects in a chronic cocaine dependent population
    Mary R Lee
    National Institute on Alcohol Abuse and Alcoholism, Laboratory of Clinical and Translational Studies, Bethesda, MD, USA Electronic address
    Eur Neuropsychopharmacol 24:1483-91. 2014
  4. doi request reprint Gender differences in neural-behavioral response to self-observation during a novel fMRI social stress task
    Mary R Lee
    Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, United States Electronic address
    Neuropsychologia 53:257-63. 2014
  5. pmc A preliminary study suggests that nicotine and prefrontal dopamine affect cortico-striatal areas in smokers with performance feedback
    M R Lee
    Neuroimaging Research Branch, National Institute on Drug Abuse NIDA, Intramural Research Program, Baltimore, 21224, USA
    Genes Brain Behav 12:554-63. 2013
  6. pmc Effects of adjunctive intranasal oxytocin on olfactory identification and clinical symptoms in schizophrenia: results from a randomized double blind placebo controlled pilot study
    Mary R Lee
    Neuroimaging Research Branch, National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD 21224, USA
    Schizophr Res 145:110-5. 2013
  7. pmc Functional polymorphism of the mu-opioid receptor gene (OPRM1) influences reinforcement learning in humans
    Mary R Lee
    National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland, United States of America
    PLoS ONE 6:e24203. 2011
  8. doi request reprint Prefrontal white matter impairment in substance users depends upon the catechol-o-methyl transferase (COMT) val158met polymorphism
    Xiaochu Zhang
    Neuroimaging Research Branch, National Institute on Drug Abuse, NIH, Baltimore, MD 21224, USA
    Neuroimage 69:62-9. 2013
  9. pmc Hepatic, lipid and genetic factors associated with obesity: crosstalk with alcohol dependence?
    Kimberly Goodyear
    a Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse, Bethesda, MD, USA
    World J Biol Psychiatry . 2016
  10. doi request reprint Differences Between Treatment-Seeking and Nontreatment-Seeking Alcohol-Dependent Research Participants: An Exploratory Analysis
    Matthew C H Rohn
    Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse, National Institutes of Health, Bethesda, Maryland
    Alcohol Clin Exp Res 41:414-420. 2017

Collaborators

Detail Information

Publications16

  1. pmc Relationship of plasma oxytocin levels to baseline symptoms and symptom changes during three weeks of daily oxytocin administration in people with schizophrenia
    Mary R Lee
    National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism, Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, Bethesda, MD, United States Electronic address
    Schizophr Res 172:165-8. 2016
    ..Larger studies are needed to examine the effect of exogenous OT on peripheral OT levels and the relationship between the latter and clinical symptoms. Clinical Trials.gov=NCT00884897...
  2. pmc Targeting the Oxytocin System to Treat Addictive Disorders: Rationale and Progress to Date
    Mary R Lee
    Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, National Institute on Alcohol Abuse and Alcoholism, and National Institute on Drug Abuse, 10 Center Drive, MSC 1108, Bethesda, MD, 20892 1108, USA
    CNS Drugs 30:109-23. 2016
    ..This review summarizes the preclinical as well as clinical literature to date on the oxytocin system and its relevance to drug and alcohol addiction. ..
  3. doi request reprint Complexity of oxytocin׳s effects in a chronic cocaine dependent population
    Mary R Lee
    National Institute on Alcohol Abuse and Alcoholism, Laboratory of Clinical and Translational Studies, Bethesda, MD, USA Electronic address
    Eur Neuropsychopharmacol 24:1483-91. 2014
    ..These findings are discussed in light of the human and rodent oxytocin literature. ..
  4. doi request reprint Gender differences in neural-behavioral response to self-observation during a novel fMRI social stress task
    Mary R Lee
    Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, United States Electronic address
    Neuropsychologia 53:257-63. 2014
    ..During fMRI scanning, subjects were shown alternating video clips of two..
  5. pmc A preliminary study suggests that nicotine and prefrontal dopamine affect cortico-striatal areas in smokers with performance feedback
    M R Lee
    Neuroimaging Research Branch, National Institute on Drug Abuse NIDA, Intramural Research Program, Baltimore, 21224, USA
    Genes Brain Behav 12:554-63. 2013
    ....
  6. pmc Effects of adjunctive intranasal oxytocin on olfactory identification and clinical symptoms in schizophrenia: results from a randomized double blind placebo controlled pilot study
    Mary R Lee
    Neuroimaging Research Branch, National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD 21224, USA
    Schizophr Res 145:110-5. 2013
    ....
  7. pmc Functional polymorphism of the mu-opioid receptor gene (OPRM1) influences reinforcement learning in humans
    Mary R Lee
    National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland, United States of America
    PLoS ONE 6:e24203. 2011
    ....
  8. doi request reprint Prefrontal white matter impairment in substance users depends upon the catechol-o-methyl transferase (COMT) val158met polymorphism
    Xiaochu Zhang
    Neuroimaging Research Branch, National Institute on Drug Abuse, NIH, Baltimore, MD 21224, USA
    Neuroimage 69:62-9. 2013
    ....
  9. pmc Hepatic, lipid and genetic factors associated with obesity: crosstalk with alcohol dependence?
    Kimberly Goodyear
    a Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse, Bethesda, MD, USA
    World J Biol Psychiatry . 2016
    ..However, data in the literature are not conclusive. Therefore, this study aimed to identify the association between alcohol dependence and obesity-related factors, including biochemical and genetic factors...
  10. doi request reprint Differences Between Treatment-Seeking and Nontreatment-Seeking Alcohol-Dependent Research Participants: An Exploratory Analysis
    Matthew C H Rohn
    Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse, National Institutes of Health, Bethesda, Maryland
    Alcohol Clin Exp Res 41:414-420. 2017
    ..However, despite their crucial role in alcohol-related research, these 2 groups are poorly defined. In this exploratory analysis, we attempt to better define the phenotypic differences between these 2 experimentally relevant populations...
  11. pmc Effect of Functionally Significant Deiodinase Single Nucleotide Polymorphisms on Drinking Behavior in Alcohol Dependence: An Exploratory Investigation
    Mary R Lee
    Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse, National Institutes of Health, Bethesda, Maryland
    Alcohol Clin Exp Res 39:1665-70. 2015
    ..In the context of alcohol use, functionally significant single nucleotide polymorphisms (SNPs) of these deiodinase genes may play a role in HPT dysfunction...
  12. pmc Mapping of reinforcing and analgesic effects of the mu opioid agonist endomorphin-1 in the ventral midbrain of the rat
    Thomas C Jhou
    Behavioral Neuroscience Branch, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, MD, USA
    Psychopharmacology (Berl) 224:303-12. 2012
    ....
  13. pmc Serum Insulin Levels Are Reduced by Intravenous Ghrelin Administration but Do Not Correlate with Alcohol Craving in Alcohol-Dependent Individuals
    Carolina L Haass-Koffler
    Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD Drs Haass Koffler, Lee, and Leggio Center for Alcohol and Addiction Studies, Department of Behavioral and Social Sciences Dr Haass Koffler, Ms Giovenco, and Dr Leggio, and Center for Alcohol and Addiction Studies, Department of Psychiatry and Human Behavior Drs Haass Koffler, Zywiak, Kenna, and Swift, Brown University, Providence, RI Veterans Affairs Medical Center, Providence, RI Dr Swift Departments of Pathology, Neurology, and Neurosurgery, Rhode Island Hospital and The Warren Alpert Medical School of Brown University, Providence, RI Dr de la Monte
    Int J Neuropsychopharmacol . 2016
    ..Additionally, we explored possible correlations between serum insulin and alcohol craving, since a correlation between insulin and alcohol craving was previously reported...
  14. pmc Treatment of Alcohol Use Disorder in Patients with Alcoholic Liver Disease
    Lorenzo Leggio
    Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse, National Institutes of Health, Bethesda, Md Center for Alcohol and Addiction Studies, Department of Behavioral and Social Sciences, Brown University, Providence, RI Electronic address
    Am J Med 130:124-134. 2017
    ..Finally, more efforts are needed to integrate treatments across disciplines toward patient-centered approaches in the management of patients with alcohol use disorder and alcoholic liver disease...
  15. doi request reprint Combined pharmacotherapies for the management of alcoholism: rationale and evidence to date
    Mary R Lee
    Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 10 Center Drive 10CRC 15330 MSC 1108, Room 1 5429, Bethesda, MD, 20892 1108, USA
    CNS Drugs 28:107-19. 2014
    ..Limitations of the current published studies and possible future directions for new combinations are discussed...
  16. doi request reprint Addiction and corticotropin-releasing hormone type 1 receptor antagonist medications
    Carlo Contoreggi
    Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA
    Ann N Y Acad Sci 1282:107-18. 2013
    ..Investigators designing future trials might refocus their understanding of addiction and treatment in this new direction...