Maricel G Kann

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Protein interactions and disease: computational approaches to uncover the etiology of diseases
    Maricel G Kann
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20894, USA
    Brief Bioinform 8:333-46. 2007
  2. pmc The identification of complete domains within protein sequences using accurate E-values for semi-global alignment
    Maricel G Kann
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20894, USA
    Nucleic Acids Res 35:4678-85. 2007
  3. ncbi request reprint Predicting protein domain interactions from coevolution of conserved regions
    Maricel G Kann
    Department of Health and Human Services, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland 20894, USA
    Proteins 67:811-20. 2007
  4. pmc Threshold Average Precision (TAP-k): a measure of retrieval designed for bioinformatics
    Hyrum D Carroll
    National Center for Biotechnology Information, Bethesda, MD 20894, USA
    Bioinformatics 26:1708-13. 2010
  5. ncbi request reprint A structure-based method for protein sequence alignment
    Maricel G Kann
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20894, USA
    Bioinformatics 21:1451-6. 2005
  6. pmc Histone structure and nucleosome stability
    Leonardo Mariño-Ramírez
    Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA
    Expert Rev Proteomics 2:719-29. 2005
  7. ncbi request reprint Modeling cell heterogeneity: from single-cell variations to mixed cells
    Eric Batchelor
    Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20894, USA
    Pac Symp Biocomput . 2013
  8. pmc Chapter 4: Protein interactions and disease
    Mileidy W Gonzalez
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Comput Biol 8:e1002819. 2012
  9. pmc Predicting protein-protein interaction by searching evolutionary tree automorphism space
    Raja Jothi
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health Bethesda, MD 20894, USA
    Bioinformatics 21:i241-50. 2005
  10. ncbi request reprint Performance evaluation of a new algorithm for the detection of remote homologs with sequence comparison
    Maricel G Kann
    Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109 1055, USA
    Proteins 48:367-76. 2002

Detail Information

Publications11

  1. ncbi request reprint Protein interactions and disease: computational approaches to uncover the etiology of diseases
    Maricel G Kann
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20894, USA
    Brief Bioinform 8:333-46. 2007
    ..Recent contributions from genetics, protein structure and protein interaction network analyses to the understanding of diseases are discussed here...
  2. pmc The identification of complete domains within protein sequences using accurate E-values for semi-global alignment
    Maricel G Kann
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20894, USA
    Nucleic Acids Res 35:4678-85. 2007
    ..When searching for complete protein domains, therefore, GLOBAL avoids disadvantages commonly associated with HMMs, yet maintains their superior retrieval performance...
  3. ncbi request reprint Predicting protein domain interactions from coevolution of conserved regions
    Maricel G Kann
    Department of Health and Human Services, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland 20894, USA
    Proteins 67:811-20. 2007
    ..We provide a theoretical validation of our results leading to new insights into the interplay between coevolution and speciation of interacting proteins...
  4. pmc Threshold Average Precision (TAP-k): a measure of retrieval designed for bioinformatics
    Hyrum D Carroll
    National Center for Biotechnology Information, Bethesda, MD 20894, USA
    Bioinformatics 26:1708-13. 2010
    ..Unfortunately, the pooled ROC(n) score does not faithfully reflect actual usage of retrieval algorithms. Additionally, a pooled ROC(n) score can be very sensitive to retrieval results from as little as a single query...
  5. ncbi request reprint A structure-based method for protein sequence alignment
    Maricel G Kann
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20894, USA
    Bioinformatics 21:1451-6. 2005
    ....
  6. pmc Histone structure and nucleosome stability
    Leonardo Mariño-Ramírez
    Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA
    Expert Rev Proteomics 2:719-29. 2005
    ..The authors review recent findings on the structure of chromatin that confirm previous interparticle interactions observed in crystal structures...
  7. ncbi request reprint Modeling cell heterogeneity: from single-cell variations to mixed cells
    Eric Batchelor
    Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20894, USA
    Pac Symp Biocomput . 2013
    ....
  8. pmc Chapter 4: Protein interactions and disease
    Mileidy W Gonzalez
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Comput Biol 8:e1002819. 2012
    ..We will describe the application of protein interaction networks as a translational approach to the study of human disease and evaluate the challenges faced by these approaches...
  9. pmc Predicting protein-protein interaction by searching evolutionary tree automorphism space
    Raja Jothi
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health Bethesda, MD 20894, USA
    Bioinformatics 21:i241-50. 2005
    ..Many of these methods are limited by the fact that they can handle only a small number of protein sequences. Also, details on evolutionary tree topology are missing as they use similarity matrices in lieu of the trees...
  10. ncbi request reprint Performance evaluation of a new algorithm for the detection of remote homologs with sequence comparison
    Maricel G Kann
    Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109 1055, USA
    Proteins 48:367-76. 2002
    ....
  11. pmc MutDB: update on development of tools for the biochemical analysis of genetic variation
    Arti Singh
    Center for Computational Biology and Bioinfomatics, Department of Medical and Molecular Genetics, Indiana University School of Medicine, 410 W 10th Street, Suite 5000, Indianapolis, IN 46202, USA
    Nucleic Acids Res 36:D815-9. 2008
    ....