Linda C Harlan

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Trends in the treatment and survival for local and regional cutaneous melanoma in a US population-based study
    Linda C Harlan
    Applied Research Program, National Cancer Institute, Bethesda, MD, USA
    Melanoma Res 21:547-54. 2011
  2. ncbi request reprint Factors associated with initial therapy for clinically localized prostate cancer: prostate cancer outcomes study
    L C Harlan
    Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Natl Cancer Inst 93:1864-71. 2001
  3. ncbi request reprint Adjuvant therapy for breast cancer: practice patterns of community physicians
    Linda C Harlan
    Applied Research Program, National Cancer Institute, Bethesda, MD 20892, USA
    J Clin Oncol 20:1809-17. 2002
  4. pmc Breast cancer in men in the United States: a population-based study of diagnosis, treatment, and survival
    Linda C Harlan
    Applied Research Program, National Cancer Institute, Bethesda, Maryland 20892 7344, USA
    Cancer 116:3558-68. 2010
  5. pmc Comorbidities, therapy, and newly diagnosed conditions for women with early stage breast cancer
    Linda C Harlan
    Applied Research Program, National Cancer Institute, 6130 Executive Blvd, MSC 7344, Bethesda, MD 20892, USA
    J Cancer Surviv 3:89-98. 2009
  6. ncbi request reprint Community-based use of chemotherapy and hormonal therapy for early-stage breast cancer: 1987-2000
    Linda C Harlan
    Applied Research Program, National Cancer Institute, Bethesda, MD 20892 7344, USA
    J Clin Oncol 24:872-7. 2006
  7. ncbi request reprint Trends in surgery and chemotherapy for women diagnosed with ovarian cancer in the United States
    Linda C Harlan
    National Cancer Institute, 6130 Executive Blvd, MSC 7344, Bethesda, MD 20892 7344, USA
    J Clin Oncol 21:3488-94. 2003
  8. ncbi request reprint Insurance status and the use of guideline therapy in the treatment of selected cancers
    Linda C Harlan
    Division of Cancer Control and Population Sciences, Cancer Therapy Evaluation Program, National Cancer Institute, National Institute of Health, Bethesda, MD 20892 7344, USA
    J Clin Oncol 23:9079-88. 2005
  9. pmc Recruitment and follow-up of adolescent and young adult cancer survivors: the AYA HOPE Study
    Linda C Harlan
    National Cancer Institute, 6130 Executive Blvd, MSC 7344, Bethesda, MD 20892 7344, USA
    J Cancer Surviv 5:305-14. 2011
  10. pmc Multiple myeloma treatment transformed: a population-based study of changes in initial management approaches in the United States
    Joan L Warren
    National Cancer Institute, Bethesda, MD 20892 7344, USA
    J Clin Oncol 31:1984-9. 2013

Detail Information

Publications45

  1. pmc Trends in the treatment and survival for local and regional cutaneous melanoma in a US population-based study
    Linda C Harlan
    Applied Research Program, National Cancer Institute, Bethesda, MD, USA
    Melanoma Res 21:547-54. 2011
    ..Survival was associated with tumor thickness. Early detection when the tumor thickness is less may decrease mortality. Future research should especially target decreasing the disparity in survival between men and women...
  2. ncbi request reprint Factors associated with initial therapy for clinically localized prostate cancer: prostate cancer outcomes study
    L C Harlan
    Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Natl Cancer Inst 93:1864-71. 2001
    ..We examined the association of sociodemographic and clinical characteristics with four management options: radical prostatectomy, radiation therapy, hormonal therapy, and watchful waiting...
  3. ncbi request reprint Adjuvant therapy for breast cancer: practice patterns of community physicians
    Linda C Harlan
    Applied Research Program, National Cancer Institute, Bethesda, MD 20892, USA
    J Clin Oncol 20:1809-17. 2002
    ..We evaluated the use of adjuvant therapy for breast cancer using the National Institutes of Health (NIH) Consensus Development Conference statements as guideposts for assessing how rapidly community physicians adopt recommended therapies...
  4. pmc Breast cancer in men in the United States: a population-based study of diagnosis, treatment, and survival
    Linda C Harlan
    Applied Research Program, National Cancer Institute, Bethesda, Maryland 20892 7344, USA
    Cancer 116:3558-68. 2010
    ..Recommendations suggest treating men who are diagnosed with breast cancer using the guidelines for postmenopausal women; however, to date, no population-based studies have evaluated patterns of care...
  5. pmc Comorbidities, therapy, and newly diagnosed conditions for women with early stage breast cancer
    Linda C Harlan
    Applied Research Program, National Cancer Institute, 6130 Executive Blvd, MSC 7344, Bethesda, MD 20892, USA
    J Cancer Surviv 3:89-98. 2009
    ..To describe comorbidities in breast cancer patients at diagnosis and examine factors associated with self-reported comorbidities 30 months post-diagnosis...
  6. ncbi request reprint Community-based use of chemotherapy and hormonal therapy for early-stage breast cancer: 1987-2000
    Linda C Harlan
    Applied Research Program, National Cancer Institute, Bethesda, MD 20892 7344, USA
    J Clin Oncol 24:872-7. 2006
    ..We describe trends in the use of chemotherapy and hormonal therapy by nodal and estrogen receptor (ER) status in women with early-stage breast cancer...
  7. ncbi request reprint Trends in surgery and chemotherapy for women diagnosed with ovarian cancer in the United States
    Linda C Harlan
    National Cancer Institute, 6130 Executive Blvd, MSC 7344, Bethesda, MD 20892 7344, USA
    J Clin Oncol 21:3488-94. 2003
    ..We examined patterns of care in a population-based sample of 601 ovarian cancer patients diagnosed in 1991, and a sample of 566 women was selected in 1996 to examine trends in care...
  8. ncbi request reprint Insurance status and the use of guideline therapy in the treatment of selected cancers
    Linda C Harlan
    Division of Cancer Control and Population Sciences, Cancer Therapy Evaluation Program, National Cancer Institute, National Institute of Health, Bethesda, MD 20892 7344, USA
    J Clin Oncol 23:9079-88. 2005
    ..This study estimates the impact of type of insurance coverage on the receipt of guideline therapy in a population-based sample of cancer patients treated in the community...
  9. pmc Recruitment and follow-up of adolescent and young adult cancer survivors: the AYA HOPE Study
    Linda C Harlan
    National Cancer Institute, 6130 Executive Blvd, MSC 7344, Bethesda, MD 20892 7344, USA
    J Cancer Surviv 5:305-14. 2011
    ..Furthermore, participation in research by AYAs is typically low. We conducted a study to examine the feasibility of recruiting a population-based sample of AYA survivors to examine issues of treatment and health outcomes...
  10. pmc Multiple myeloma treatment transformed: a population-based study of changes in initial management approaches in the United States
    Joan L Warren
    National Cancer Institute, Bethesda, MD 20892 7344, USA
    J Clin Oncol 31:1984-9. 2013
    ..Despite improved outcomes for multiple myeloma, little is known about changes in initial treatment at the population level for US patients. We report trends in treatment practices...
  11. pmc Patterns of colorectal cancer care in Europe, Australia, and New Zealand
    Neetu Chawla
    Health Services and Economics Branch Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, 9609 Medical Center Dr, Room 3E346, Rockville, MD 20852, USA
    J Natl Cancer Inst Monogr 2013:36-61. 2013
    ..Future research and policy efforts should emphasize increased comparability of data systems, promote data standardization, and encourage collaboration between and within European cancer registries and administrative databases. ..
  12. pmc Population-based estimate of the prevalence of HER-2 positive breast cancer tumors for early stage patients in the US
    Kathleen A Cronin
    Surveillance Research Program, National Cancer Institute, Bethesda, Maryland, USA
    Cancer Invest 28:963-8. 2010
    ..Tumor grade and race were associated with HER-2 for women aged ≥ 50 years after controlling for other variables. HER-2 varies by age and by race and tumor in older women...
  13. pmc Cancer, comorbidities, and health-related quality of life of older adults
    Ashley Wilder Smith
    National Cancer Institute NCI, Bethesda, MD 20892 7344, USA
    Health Care Financ Rev 29:41-56. 2008
    ..Negative associations were most pronounced in those with two or more comorbidities and in those diagnosed with cancer within the past year...
  14. ncbi request reprint Pre-operative imaging, surgery and adjuvant therapy for women diagnosed with cancer of the corpus uteri in community practice in the United States
    Edward L Trimble
    National Cancer Institute, Surgery Section, 6130 Executive Boulevard, Ste 741, M, Bethesda, MD 20892 7436, USA
    Gynecol Oncol 96:741-8. 2005
    ..Non-Hispanic black women are less often diagnosed with endometrial cancer than are non-Hispanic white women, but are more likely to die of their disease. Reasons for this disparity in outcome are not well understood...
  15. ncbi request reprint Do patients consistently report comorbid conditions over time?: results from the prostate cancer outcomes study
    Carrie N Klabunde
    Health Services and Economics Branch, Applied Research Program, Surveillance Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland 20892 7344, USA
    Med Care 43:391-400. 2005
    ..Comorbidity is an important dimension of patient health status. However, limited attention has been given to assessing the reliability of patient-reported data on comorbid conditions...
  16. ncbi request reprint Racial/ethnic variation in clinical presentation, treatment, and survival among breast cancer patients under age 35
    Vickie L Shavers
    Applied Research Program, Health Service and Economics Branch, Division of Cancer Control and Population Science, National Cancer Institute, 6130 Executive Boulevard, MSC 7344, EPN Room 4005, Bethesda, MD 20892 7344, USA
    Cancer 97:134-47. 2003
    ....
  17. ncbi request reprint Utility of the SEER-Medicare data to identify chemotherapy use
    Joan L Warren
    Applied Research Program, National Cancer Institute, Bethesda, Maryland 20892 7344
    Med Care 40:IV-55-61. 2002
    ..However, the validity and completeness of these data as a source of information has not been established...
  18. ncbi request reprint Trends in use of adjuvant multi-agent chemotherapy and tamoxifen for breast cancer in the United States: 1975-1999
    Angela Mariotto
    Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 8317, USA
    J Natl Cancer Inst 94:1626-34. 2002
    ..We evaluated trends in the use of adjuvant multi-agent chemotherapy, tamoxifen, and the combination of both treatments for early-stage breast cancer in the United States from 1975 through 1999...
  19. ncbi request reprint Patterns of care for adjuvant therapy in a random population-based sample of patients diagnosed with colorectal cancer
    Deirdre P Cronin
    Surveillance Research Program, DCCPS, National Cancer Institute, Bethesda, Maryland, USA
    Am J Gastroenterol 101:2308-18. 2006
    ..This study tracks dissemination of these treatments for patients diagnosed with stage II and III disease and compares risk of death for those who received guideline therapy to those who did not...
  20. ncbi request reprint Data sources for measuring comorbidity: a comparison of hospital records and medicare claims for cancer patients
    Carrie N Klabunde
    Health Services and Economics Branch, Applied Research Program, National Cancer Institute, Bethesda, MD 20892 7344, USA
    Med Care 44:921-8. 2006
    ..Identifying appropriate comorbidity data sources is a key consideration in health services and outcomes research...
  21. doi request reprint A population-based study of therapy and survival for patients with head and neck cancer treated in the community
    Claudio Dansky Ullmann
    Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, MD, USA
    Cancer 118:4452-61. 2012
    ..The objective of this study was to examine patterns of care and survival in a population-based sample of patients with head and neck cancer (HNC) who were treated in the community or in hospitals that had residency training programs...
  22. doi request reprint Is mode of breast cancer detection associated with cancer treatment in the United States?
    K Robin Yabroff
    Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892 7344, USA
    Cancer 112:1011-9. 2008
    ..In the current study, the authors explored whether detection by mammography was associated with greater use of guideline-consistent breast cancer treatment among patients with recently diagnosed breast cancer in the United States...
  23. ncbi request reprint Five-year outcomes after prostatectomy or radiotherapy for prostate cancer: the prostate cancer outcomes study
    Arnold L Potosky
    Division of Cancer Control and Population Sciences, National Cancer Institute, EPN Rm 4005, 6130 Executive Blvd, MSC 7344, Bethesda, MD 20892 7344, USA
    J Natl Cancer Inst 96:1358-67. 2004
    ..We present treatment-specific quality-of-life outcomes for prostate cancer patients 5 years after initial diagnosis...
  24. pmc Clinical trial participation and time to treatment among adolescents and young adults with cancer: does age at diagnosis or insurance make a difference?
    Helen M Parsons
    Applied Research Program, National Cancer Institute, Bethesda, MD 20892 7344, USA
    J Clin Oncol 29:4045-53. 2011
    ..To identify current trends in AYA care, we examined patterns of clinical trial participation, time to treatment, and provider characteristics in a population-based sample of AYA patients with cancer...
  25. ncbi request reprint Racial/ethnic patterns of care for cancers of the oral cavity, pharynx, larynx, sinuses, and salivary glands
    Vickie L Shavers
    National Cancer Institute, Division of Cancer Control and Population Science, Applied Research Program, Health Services and Economic Branch, Bethesda, MD 20892 7344, USA
    Cancer Metastasis Rev 22:25-38. 2003
    ..We examine racial/ethnic variation in tumor characteristics, treatment practices, and their relationship to survival for cancers of the oral cavity, pharynx, larynx, nasal cavity and salivary glands...
  26. pmc Use of appropriate initial treatment among adolescents and young adults with cancer
    Arnold L Potosky
    Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC ALP Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD LCH Cook Children s Medical Center and University of North Texas Health Science Center Fort Worth, TX KA Public Health Institute Cancer Registry of Greater California, Sacramento, CA RDC Monroe Carell Jr Children s Hospital, Vanderbilt Ingram Cancer Center, Nashville, TN DLF Keck School of Medicine, University of Southern California, Los Angeles, CA ASH Departments of Oncology and Pathology, Wayne State University, Detroit, MI IK Cancer Prevention Institute of California, Fremont, CA THMK School of Medicine, Stanford University, Stanford, CA THMK Information Management Services, Inc, Silver Spring, MD GK Epidemiology Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA SMS Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, MD NLS Department of Urology, Division of Pediatric Urology, University of Washington, Seattle Children s Hospital, Seattle, WA MS Department of Epidemiology, University of Iowa, Iowa City, IA MMW Louisiana State University, New Orleans, LA XCW
    J Natl Cancer Inst 106:. 2014
    ..There has been little improvement in the survival of adolescent and young adult (AYA) cancer patients aged 15 to 39 years relative to other age groups, raising the question of whether such patients receive appropriate initial treatment...
  27. ncbi request reprint Knowledge of Clinical Trial Availability and Reasons for Nonparticipation Among Adolescent and Young Adult Cancer Patients: A Population-based Study
    Margarett Shnorhavorian
    Department of Urology, Division of Pediatric Urology, University of Washington, Seattle Children s Hospital Department of Epidemiology, University of Washington Epidemiology Program, Fred Hutchinson Cancer Research Center, Seattle, WA Epidemiology Program, School of Public Health, Louisiana State University Health Sciences Center, New Orleans, LA Keck School of Medicine, University of Southern California, Los Angeles Department of Public Health Sciences, School of Medicine, University of California, Davis, Davis, CA Department of Internal Medicine, Division of Hematology and Oncology, School of Medicine, University of California, Davis, Sacramento, CA Departments of Oncology and Pathology, School of Medicine, Wayne State University, Detroit, MI Department of Epidemiology, University of Iowa, Iowa City, IA Applied Research Program, National Cancer Institute, Bethesda, MD
    Am J Clin Oncol . 2016
    ..Adolescent and young adult (AYA) cancer patients are underrepresented in clinical trials, but the reasons for this phenomenon are unknown...
  28. doi request reprint Ductal carcinoma in situ: trends in treatment over time in the US
    Jo Anne Zujewski
    National Cancer Institute, CTEP, Bethesda, MD, USA
    Breast Cancer Res Treat 127:251-7. 2011
    ..Despite positive HER-2 tests no women received trastuzumab as of 2005. Despite the lack of clinical trials evidence, aromatase inhibitors are being prescribed for women with DCIS...
  29. ncbi request reprint The frequency of ipsilateral second tumors after breast-conserving surgery for DCIS: a population based analysis
    Joan L Warren
    Health Services and Economics Branch Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland 20892 7344, USA
    Cancer 104:1840-8. 2005
    ..This analysis of women treated with breast-conserving surgery (BCS) evaluated the impact of radiation therapy (RT) in patient outcomes...
  30. pmc Patterns of colorectal cancer care in the United States and Canada: a systematic review
    Ebonee N Butler
    Health Services and Economics Branch Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, 9609 Medical Center Dr 3E436, Rockville, MD 20850, USA
    J Natl Cancer Inst Monogr 2013:13-35. 2013
    ....
  31. pmc Feasibility study for collection of HER2 data by National Cancer Institute (NCI) Surveillance, Epidemiology, and End Results (SEER) Program central cancer registries
    Marsha E Reichman
    Division of Cancer Control and Population Sciences, National Cancer Institute, 6130 Executive Boulevard, Suite 6138, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 19:144-7. 2010
    ....
  32. pmc Patterns of care for women with cervical cancer in the United States
    Edward L Trimble
    National Cancer Institute, Surgery Section, Bethesda, Maryland 20892 7436, USA
    Cancer 113:743-9. 2008
    ..This analysis was initiated to determine any systemic changes in management of cervical cancers...
  33. ncbi request reprint Untreated cervical cancer in the United States
    Edward L Trimble
    Surgery Section, National Cancer Institute, 6130 Executive Boulevard, Suite 741, MSC 7436, Bethesda, MD 20892 7436, USA
    Gynecol Oncol 96:271-7. 2005
    ..To evaluate treatment patterns, including lack of treatment, among women diagnosed with cervical cancer in the United States...
  34. pmc Patterns of Colorectal Cancer Care in the United States: 1990-2010
    Caitlin C Murphy
    Affiliations Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC CCM, JLL Healthcare Delivery Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD LCH, AMG Department of Epidemiology, University of Iowa, Iowa City, IA CFL
    J Natl Cancer Inst 107:. 2015
    ..Colorectal cancer (CRC) mortality has declined in the United States, in part because of advances in treatment. Few studies have evaluated the adoption of therapies and temporal changes in patterns of care...
  35. pmc Racial/ethnic patterns of care for pancreatic cancer
    Vickie L Shavers
    Applied Research Program, National Cancer Institute, Bethesda, Maryland 20892, USA
    J Palliat Med 12:623-30. 2009
    ..Racial/ethnic cancer treatment disparities have been observed for many cancer sites. We examine patterns of care in a population-based sample of African American, Hispanic and non-Hispanic white patients diagnosed with pancreatic cancer...
  36. pmc Temporal patterns of care and outcomes of non-small cell lung cancer patients in the United States diagnosed in 1996, 2005, and 2010
    Filip Kaniski
    National Cancer Institute, Division of Cancer Control and Population Sciences, Healthcare Delivery Research Program, United States
    Lung Cancer 103:66-74. 2017
    ..Lung cancer remains a common and deadly cancer in the United States. This study evaluated factors associated with stage-specific cancer therapy and survival focusing on temporal trends and sociodemographic disparities...
  37. ncbi request reprint Dissemination of adjuvant multiagent chemotherapy and tamoxifen for breast cancer in the United States using estrogen receptor information: 1975-1999
    Angela B Mariotto
    Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892 8317, USA
    J Natl Cancer Inst Monogr . 2006
    ..These two inputs, dissemination and efficacy, are key pieces for models that investigate the effect of breast cancer adjuvant therapy on the decline of U.S. breast cancer mortality...
  38. doi request reprint Treatment of de novo acute myeloid leukemia in the United States: a report from the Patterns of Care program
    V Paul Doria-Rose
    National Cancer Institute, Bethesda, MD, USA
    Leuk Lymphoma 55:2549-55. 2014
    ..Age and APL diagnosis were the strongest predictors of treatment and survival. Trends in dissemination of novel diagnostic tests and treatments and in survival will be monitored by POC in future years...
  39. pmc Treatment of small cell lung cancer in academic and community settings: factors associated with receiving standard therapy and survival
    Helen M Parsons
    From the Applied Research Program, National Cancer Institute, Bethesda, MD Information Management Services, Inc, Calverton, MD and Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, MD
    Cancer J 20:97-104. 2014
    ..Whereas treatment patterns and outcomes have been evaluated for patients with SCLC in clinical trials, population-based practice patterns are not well known...
  40. ncbi request reprint Age, sex, and racial differences in the use of standard adjuvant therapy for colorectal cancer
    Arnold L Potosky
    Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Clin Oncol 20:1192-202. 2002
    ..Trends, patterns, and outcomes of adjuvant therapy for colorectal cancer, focusing on age, sex, and racial/ethnic differences, are reported...
  41. pmc Thyroid cancer presentation and treatment in the United States
    Lindsey Enewold
    National Cancer Institute, Bethesda, MD, USA
    Ann Surg Oncol 22:1789-97. 2015
    ..Thyroid cancer incidence is rising in the United States. Although overall thyroid cancer survival is high, prognostic stratification schemes have been developed to better delineate patients with poor prognoses...
  42. doi request reprint Gastrointestinal stromal tumors: treatment patterns of a population-based sample
    Linda C Harlan
    Applied Research Program, National Cancer Institute, Bethesda, Maryland
    J Surg Oncol 111:702-7. 2015
    ..The National Cancer Institute (NCI) annually confirms therapy with treating physicians on a sample of patients diagnosed with a specific cancer...
  43. pmc Race and Insurance Differences in the Receipt of Adjuvant Chemotherapy Among Patients With Stage III Colon Cancer
    Caitlin C Murphy
    Caitlin C Murphy, University of North Carolina at Chapel Hill, Chapel Hill, NC and Linda C Harlan, Joan L Warren, Ann M Geiger, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD
    J Clin Oncol 33:2530-6. 2015
    ..Although the incidence and mortality of colon cancer in the United States has declined over the past two decades, blacks have worse outcomes than whites. Variations in treatment may contribute to mortality differentials...
  44. ncbi request reprint Renal cell cancer: a shift in approaches for treatment of advanced disease in the United States
    Matthew P Banegas
    From the Divisions of Cancer Control and Population Sciences and Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland
    J Natl Compr Canc Netw 12:1271-9. 2014
    ..As the diffusion of new therapies continues, it will be imperative to understand how variation in care for RCC will impact health outcomes and costs of care. ..
  45. pmc Identifying specific chemotherapeutic agents in Medicare data: a validation study
    Jennifer L Lund
    Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Med Care 51:e27-34. 2013
    ..Misclassification of chemotherapy could bias estimates of frequency and association, warranting an updated assessment...