F S Hall

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Methamphetamine-induced locomotor activity and sensitization in dopamine transporter and vesicular monoamine transporter 2 double mutant mice
    Setsu Fukushima
    Department of Biological Psychiatry, Tohoku University Graduate School of Medicine, 1 1 Seiryo machi, Sendai, 980 8574, Japan
    Psychopharmacology (Berl) 193:55-62. 2007
  2. ncbi request reprint Maternal deprivation of neonatal rats produces enduring changes in dopamine function
    F S Hall
    Department of Experimental Psychology, University of Cambridge, England
    Synapse 32:37-43. 1999
  3. ncbi request reprint Reduced behavioral effects of cocaine in heterozygous brain-derived neurotrophic factor (BDNF) knockout mice
    F Scott Hall
    Molecular Neurobiology Branch, National Institute on Drug Abuse IRP, NIH DHHS, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Neuropsychopharmacology 28:1485-90. 2003
  4. ncbi request reprint mu-Opioid receptor knockout mice display reduced cocaine conditioned place preference but enhanced sensitization of cocaine-induced locomotion
    F Scott Hall
    Molecular Neurobiology Branch, National Institute on Drug Abuse IRP, NIH DHHS, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Brain Res Mol Brain Res 121:123-30. 2004
  5. pmc Dopamine signaling is required for depolarization-induced slow current in cerebellar Purkinje cells
    Yu Shin Kim
    Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Neurosci 29:8530-8. 2009
  6. pmc Decreased vesicular monoamine transporter 2 (VMAT2) and dopamine transporter (DAT) function in knockout mice affects aging of dopaminergic systems
    F S Hall
    Molecular Neurobiology Branch, Intramural Research Program, NIDA, NIH DHHS, Baltimore, MD 21224, USA Electronic address
    Neuropharmacology 76:146-55. 2014
  7. pmc Implications of genome wide association studies for addiction: are our a priori assumptions all wrong?
    F Scott Hall
    Molecular Neurobiology Branch, National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD 21224, United States Electronic address
    Pharmacol Ther 140:267-79. 2013
  8. pmc Have studies of the developmental regulation of behavioral phenotypes revealed the mechanisms of gene-environment interactions?
    F Scott Hall
    Molecular Neurobiology Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 333 Cassel Drive, Baltimore, MD 21224, United States
    Physiol Behav 107:623-40. 2012
  9. doi request reprint Effects of neurotensin gene knockout in mice on the behavioral effects of cocaine
    F Scott Hall
    Molecular Neurobiology Branch, National Institute on Drug Abuse, NIH DHHS, 333 Cassell Drive, Baltimore, MD 21224, USA
    Psychopharmacology (Berl) 219:35-45. 2012
  10. pmc A greater role for the norepinephrine transporter than the serotonin transporter in murine nociception
    F S Hall
    National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD 21224, USA
    Neuroscience 175:315-27. 2011

Collaborators

Detail Information

Publications34

  1. ncbi request reprint Methamphetamine-induced locomotor activity and sensitization in dopamine transporter and vesicular monoamine transporter 2 double mutant mice
    Setsu Fukushima
    Department of Biological Psychiatry, Tohoku University Graduate School of Medicine, 1 1 Seiryo machi, Sendai, 980 8574, Japan
    Psychopharmacology (Berl) 193:55-62. 2007
    ..However, the relative impact of heterozygous DAT and VMAT2 knockouts (KOs) on the behavioral effects of MAP remains unknown...
  2. ncbi request reprint Maternal deprivation of neonatal rats produces enduring changes in dopamine function
    F S Hall
    Department of Experimental Psychology, University of Cambridge, England
    Synapse 32:37-43. 1999
    ..Thus, behavioral responses to d-amphetamine are diminished in maternally deprived rats despite apparent increases in presynaptic dopaminergic function in the NAC...
  3. ncbi request reprint Reduced behavioral effects of cocaine in heterozygous brain-derived neurotrophic factor (BDNF) knockout mice
    F Scott Hall
    Molecular Neurobiology Branch, National Institute on Drug Abuse IRP, NIH DHHS, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Neuropsychopharmacology 28:1485-90. 2003
    ..Furthermore, these data support suggestions that differences in human BDNF expression may underlie associations between markers near the human BDNF gene locus and drug addiction...
  4. ncbi request reprint mu-Opioid receptor knockout mice display reduced cocaine conditioned place preference but enhanced sensitization of cocaine-induced locomotion
    F Scott Hall
    Molecular Neurobiology Branch, National Institute on Drug Abuse IRP, NIH DHHS, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Brain Res Mol Brain Res 121:123-30. 2004
    ..The reduced cocaine reward identified in heterozygous mu-opioid receptor knockout mice supports the possibility that humans with fewer available mu-opioid receptors might experience less cocaine reward...
  5. pmc Dopamine signaling is required for depolarization-induced slow current in cerebellar Purkinje cells
    Yu Shin Kim
    Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Neurosci 29:8530-8. 2009
    ..Together, these results suggest that strong Purkinje cell depolarization produces Ca-dependent release of vesicular postsynaptic dopamine that then excites Purkinje cells in an autocrine manner...
  6. pmc Decreased vesicular monoamine transporter 2 (VMAT2) and dopamine transporter (DAT) function in knockout mice affects aging of dopaminergic systems
    F S Hall
    Molecular Neurobiology Branch, Intramural Research Program, NIDA, NIH DHHS, Baltimore, MD 21224, USA Electronic address
    Neuropharmacology 76:146-55. 2014
    ..This article is part of the Special Issue entitled 'The Synaptic Basis of Neurodegenerative Disorders'. ..
  7. pmc Implications of genome wide association studies for addiction: are our a priori assumptions all wrong?
    F Scott Hall
    Molecular Neurobiology Branch, National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD 21224, United States Electronic address
    Pharmacol Ther 140:267-79. 2013
    ....
  8. pmc Have studies of the developmental regulation of behavioral phenotypes revealed the mechanisms of gene-environment interactions?
    F Scott Hall
    Molecular Neurobiology Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 333 Cassel Drive, Baltimore, MD 21224, United States
    Physiol Behav 107:623-40. 2012
    ..It will be argued that an important purpose of some aspects of social behavior is regulation of neurobehavioral phenotypes by experience via genetic regulatory mechanisms...
  9. doi request reprint Effects of neurotensin gene knockout in mice on the behavioral effects of cocaine
    F Scott Hall
    Molecular Neurobiology Branch, National Institute on Drug Abuse, NIH DHHS, 333 Cassell Drive, Baltimore, MD 21224, USA
    Psychopharmacology (Berl) 219:35-45. 2012
    ..Gene knockout (KO) of the neurotensin/neuromedin N precursor provides an approach to delineating possible roles of endogenous NT in psychostimulant-induced responses...
  10. pmc A greater role for the norepinephrine transporter than the serotonin transporter in murine nociception
    F S Hall
    National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD 21224, USA
    Neuroscience 175:315-27. 2011
    ..Collectively these data suggest that NET has a far greater role in determining baseline analgesia, and perhaps other analgesic effects, than SERT in mice...
  11. ncbi request reprint Molecular mechanisms underlying the rewarding effects of cocaine
    F Scott Hall
    Molecular Neurobiology Branch, NIDA IRP, NIH DHHS, Baltimore, Maryland 21224, USA
    Ann N Y Acad Sci 1025:47-56. 2004
    ..Overall, these studies indicate important requirements for several monoaminergic system genes to fully explain cocaine reward, in particular those expressed by dopamine and serotonin systems...
  12. ncbi request reprint The effects of isolation rearing on glutamate receptor NMDAR1A mRNA expression determined by in situ hybridization in Fawn hooded and Wistar rats
    F S Hall
    Molecular Neurobiology Branch, National Institute on Drug Abuse IRP, PO Box 5180, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Pharmacol Biochem Behav 73:185-91. 2002
    ..In some areas of the striatum and prefrontal cortex, this effect was greater in FH isolates than in FH socials, while in the hippocampus, the opposite was observed...
  13. ncbi request reprint Differential basis of strain and rearing effects on open-field behavior in Fawn Hooded and Wistar rats
    F S Hall
    Laboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD 20892, USA
    Physiol Behav 71:525-32. 2000
    ..Supporting these conclusions, FH rats had enhanced stimulated CORT levels, while isolation rearing was without effect...
  14. ncbi request reprint Ethanol consumption and reward are decreased in mu-opiate receptor knockout mice
    F S Hall
    Molecular Neurobiology Branch, Intramural Researcch Program, National Institute on Drug Abuse, Baltimore, MD 21224, USA
    Psychopharmacology (Berl) 154:43-9. 2001
    ..Differences in mu-opiate receptor (MOR) gene expression may modulate the rewarding effects of ethanol...
  15. ncbi request reprint Locomotor-stimulating effects of indirect dopamine agonists are attenuated in Fawn hooded rats independent of postweaning social experience
    F S Hall
    Laboratory of Clinical Studies, D I C B R, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD 20892, USA
    Pharmacol Biochem Behav 69:519-26. 2001
    ..A similar pattern of effects was observed for amphetamine in FH rats but only at the intermediate dose. The effects of strain and rearing were independent. There was no evidence for interactions between these factors...
  16. ncbi request reprint Effects of 5,7-dihydroxytryptamine depletion of tissue serotonin levels on extracellular serotonin in the striatum assessed with in vivo microdialysis: relationship to behavior
    F S Hall
    Laboratory of Clinical Studies, DICBR, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland 20892, USA
    Synapse 33:16-25. 1999
    ..Moderate levels of serotonin depletion (50-75%) produced evidence of increased anxiety, while these effects were no longer seen in rats with more severe 5-HT depletions (>75%)...
  17. ncbi request reprint Enhanced corticosterone release after a modified forced swim test in Fawn hooded rats is independent of rearing experience
    F S Hall
    National Institute on Alcohol Abuse and Alcoholism, Laboratory of Clinical Studies, Bethesda, MD 20892, USA
    Pharmacol Biochem Behav 69:629-34. 2001
    ..However, CORT levels were not correlated with the main behavioral measures assayed in this test. Nonetheless, the data confirm that FH/Har rats have altered HPA axis responses to stressors...
  18. ncbi request reprint Cocaine, reward, movement and monoamine transporters
    G R Uhl
    Molecular Neurobiology Branch, NIDA IRP, NIH, Baltimore, MD 21224, USA
    Mol Psychiatry 7:21-6. 2002
    ....
  19. ncbi request reprint Cocaine mechanisms: enhanced cocaine, fluoxetine and nisoxetine place preferences following monoamine transporter deletions
    F S Hall
    Molecular Neurobiology Branch, NIDA IRP, NIH, Box 5180, Baltimore, MD 21224, USA
    Neuroscience 115:153-61. 2002
    ....
  20. ncbi request reprint Experimental gene interaction studies with SERT mutant mice as models for human polygenic and epistatic traits and disorders
    D L Murphy
    Laboratory of Clinical Science, Building 10, Room 3D41, 10 Center Drive, NIMH, NIH DHHS, Bethesda, MD 20892 1264, USA
    Genes Brain Behav 2:350-64. 2003
    ....
  21. pmc Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference
    I Sora
    Molecular Neurobiology, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, USA
    Proc Natl Acad Sci U S A 98:5300-5. 2001
    ..These results provide insights into the brain molecular targets necessary for cocaine reward in knockout mice that develop in their absence and suggest novel strategies for anticocaine medication development...
  22. pmc Cocaine-conditioned locomotion in dopamine transporter, norepinephrine transporter and 5-HT transporter knockout mice
    F S Hall
    Molecular Neurobiology Branch, NIDA IRP NIH DHHS, 333 Cassell Drive, Baltimore, MD 21224, USA
    Neuroscience 162:870-80. 2009
    ....
  23. ncbi request reprint Mu opiate receptor gene dose effects on different morphine actions: evidence for differential in vivo mu receptor reserve
    I Sora
    Molecular Neurobiology Branch, NIDA IRP, NIH, Baltimore, MD, USA
    Neuropsychopharmacology 25:41-54. 2001
    ..They support the idea that functional mu receptor reserve differs among the diverse neuronal populations that mediate distinct properties of opiate drugs...
  24. ncbi request reprint Congenic C57BL/6 mu opiate receptor (MOR) knockout mice: baseline and opiate effects
    F S Hall
    Molecular Neurobiology Branch, National Institute on Drug Abuse, Intramural Research Program, NIH DHHS, Baltimore, MD 21224, USA
    Genes Brain Behav 2:114-21. 2003
    ....
  25. pmc Effect of KEPI (Ppp1r14c) deletion on morphine analgesia and tolerance in mice of different genetic backgrounds: when a knockout is near a relevant quantitative trait locus
    J Drgonova
    Molecular Neurobiology Branch, NIDA IRP NIH DHHS, 333 Cassell Drive, Baltimore, MD 21224, USA
    Neuroscience 165:882-95. 2010
    ..These data support roles for KEPI action in adaptive responses to repeated administration of morphine that include analgesic tolerance and drug reward...
  26. ncbi request reprint Sex-dependent modulation of ethanol consumption in vesicular monoamine transporter 2 (VMAT2) and dopamine transporter (DAT) knockout mice
    F Scott Hall
    Molecular Neurobiology Branch, NIDA IRP, NIH, DHHS, Baltimore, MD, USA
    Neuropsychopharmacology 28:620-8. 2003
    ..Thus, lifetime reductions in the expression of either DAT or VMAT2 increase ethanol consumption, dependent on sex...
  27. pmc Deletion of v7-3 (SLC6A15) transporter allows assessment of its roles in synaptosomal proline uptake, leucine uptake and behaviors
    Jana Drgonova
    Molecular Neurobiology Branch, NIDA, NIH, 333 Cassell Drive, Baltimore, MD 21224, USA
    Brain Res 1183:10-20. 2007
    ..The current results place v7-3 in the context of other brain transporters that accumulate proline and branched-chain amino acids...
  28. pmc Mu (mu) opioid receptor regulation of ethanol-induced dopamine response in the ventral striatum: evidence of genotype specific sexual dimorphic epistasis
    Martin O Job
    Division of Pharmacology, College of Pharmacy, University of Texas, 1 University Station, Austin, TX 78712, USA
    Biol Psychiatry 62:627-34. 2007
    ..Mu (mu)-opioid (MOP) receptors modulate accumbal dopamine activity, but it is not clear whether MOP receptors are involved in the mechanism of ethanol-stimulated accumbal dopamine release...
  29. ncbi request reprint Norepinephrine transporter blockade can normalize the prepulse inhibition deficits found in dopamine transporter knockout mice
    Motoyasu Yamashita
    Department of Psychobiology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
    Neuropsychopharmacology 31:2132-9. 2006
    ....
  30. ncbi request reprint Regional differences in extracellular dopamine and serotonin assessed by in vivo microdialysis in mice lacking dopamine and/or serotonin transporters
    Hao wei Shen
    Department of Molecular Psychiatry, Tokyo Institute of Psychiatry, Japan
    Neuropsychopharmacology 29:1790-9. 2004
    ..Cocaine-induced alterations in CPu DA levels in DAT-, SERT-, and DAT/SERT double-KO mice appear to provide better correlations with cocaine CPP than cocaine-induced DA level alterations in NAc or PFc...
  31. ncbi request reprint Methamphetamine-induced hyperthermia and lethal toxicity: role of the dopamine and serotonin transporters
    Yohtaro Numachi
    Department of Biological Psychiatry, Tohoku University Graduate School of Medicine, Japan
    Eur J Pharmacol 572:120-8. 2007
    ..These results suggest that DAT and SERT are key molecules for hyperthermic and lethal toxic effects of methamphetamine...
  32. ncbi request reprint Behavioral methods in cannabinoid research
    Ester Fride
    Department of Behavioral Sciences, College of Judea and Samaria, Ariel, Israel
    Methods Mol Med 123:269-90. 2006
    ....
  33. ncbi request reprint dextro- and levo-morphine attenuate opioid delta and kappa receptor agonist produced analgesia in mu-opioid receptor knockout mice
    Hsiang En Wu
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Eur J Pharmacol 531:103-7. 2006
    ..3 nmol) in wide type, heterozygous and homozygous mu-opioid receptor knockout mice. The findings provide additional evidence that mu-opioid receptors are not involved in the antianalgesia induced by dextro-morphine and levo-morphine...
  34. ncbi request reprint Effect of environmental stressors on opiate and psychostimulant reinforcement, reinstatement and discrimination in rats: a review
    Lin Lu
    Behavioral Neuroscience Branch, Intramural Research Program, National Institute on Drug Abuse, NIH DHHS, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Neurosci Biobehav Rev 27:457-91. 2003
    ..The broader implications of the data reviewed here for future research and for the treatment of opiate and psychostimulant addiction are briefly discussed...