Gang Chen

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Untangling the relatedness among correlations, part I: Nonparametric approaches to inter-subject correlation analysis at the group level
    Gang Chen
    Scientific and Statistical Computing Core, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, USA Electronic address
    Neuroimage . 2016
  2. pmc Untangling the relatedness among correlations, Part II: Inter-subject correlation group analysis through linear mixed-effects modeling
    Gang Chen
    Scientific and Statistical Computing Core, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, USA Electronic address
    Neuroimage . 2016
  3. doi request reprint Is the statistic value all we should care about in neuroimaging?
    Gang Chen
    Scientific and Statistical Computing Core, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, USA Electronic address
    Neuroimage . 2016
  4. pmc Applications of multivariate modeling to neuroimaging group analysis: a comprehensive alternative to univariate general linear model
    Gang Chen
    Scientific and Statistical Computing Core, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, USA Electronic address
    Neuroimage 99:571-88. 2014
  5. pmc Linear mixed-effects modeling approach to FMRI group analysis
    Gang Chen
    Scientific and Statistical Computing Core, NIMH NIH HHS, USA
    Neuroimage 73:176-90. 2013
  6. pmc Vector autoregression, structural equation modeling, and their synthesis in neuroimaging data analysis
    Gang Chen
    Scientific and Statistical Computing Core, NIMH NIH HHS, USA
    Comput Biol Med 41:1142-55. 2011
  7. pmc FMRI group analysis combining effect estimates and their variances
    Gang Chen
    Scientific and Statistical Computing Core, NIMH NIH DHHS, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Neuroimage 60:747-65. 2012
  8. pmc Mesolimbic recruitment by nondrug rewards in detoxified alcoholics: effort anticipation, reward anticipation, and reward delivery
    James M Bjork
    Division of Clinical Neuroscience and Behavioral Research, National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD 20892, USA
    Hum Brain Mapp 33:2174-88. 2012
  9. pmc Amygdala and ventrolateral prefrontal cortex function during anticipated peer evaluation in pediatric social anxiety
    Amanda E Guyer
    Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, 15K North Dr, Room 208, Bethesda, MD 20892 2670, USA
    Arch Gen Psychiatry 65:1303-12. 2008
  10. pmc Incentive-elicited mesolimbic activation and externalizing symptomatology in adolescents
    James M Bjork
    Division of Clinical Neuroscience and Behavioral Research, National Institute on Drug Abuse, National Institutes of Health NIH, Bethesda, MD 20892, USA
    J Child Psychol Psychiatry 51:827-37. 2010

Detail Information

Publications30

  1. pmc Untangling the relatedness among correlations, part I: Nonparametric approaches to inter-subject correlation analysis at the group level
    Gang Chen
    Scientific and Statistical Computing Core, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, USA Electronic address
    Neuroimage . 2016
    ..We examine the FPR controllability and power achievement of all the methods through simulations, as well as their performance when applied to a real experimental dataset...
  2. pmc Untangling the relatedness among correlations, Part II: Inter-subject correlation group analysis through linear mixed-effects modeling
    Gang Chen
    Scientific and Statistical Computing Core, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, USA Electronic address
    Neuroimage . 2016
    ..The new LME methodologies are shown to be both efficient and robust, and they will be publicly available in AFNI (http://afni.nimh.nih.gov)...
  3. doi request reprint Is the statistic value all we should care about in neuroimaging?
    Gang Chen
    Scientific and Statistical Computing Core, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, USA Electronic address
    Neuroimage . 2016
    ..We provide several easily adaptable recommendations for facilitating this process...
  4. pmc Applications of multivariate modeling to neuroimaging group analysis: a comprehensive alternative to univariate general linear model
    Gang Chen
    Scientific and Statistical Computing Core, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, USA Electronic address
    Neuroimage 99:571-88. 2014
    ....
  5. pmc Linear mixed-effects modeling approach to FMRI group analysis
    Gang Chen
    Scientific and Statistical Computing Core, NIMH NIH HHS, USA
    Neuroimage 73:176-90. 2013
    ..The importance of hypothesis formulation is also illustrated in the simulations. Comparisons with alternative group analysis approaches and the limitations of LME are discussed in details...
  6. pmc Vector autoregression, structural equation modeling, and their synthesis in neuroimaging data analysis
    Gang Chen
    Scientific and Statistical Computing Core, NIMH NIH HHS, USA
    Comput Biol Med 41:1142-55. 2011
    ..The unifying model, structural vector autoregression (SVAR), may improve statistical and explanatory power, and avoid some prevalent pitfalls that can occur when VAR and SEM are utilized separately...
  7. pmc FMRI group analysis combining effect estimates and their variances
    Gang Chen
    Scientific and Statistical Computing Core, NIMH NIH DHHS, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Neuroimage 60:747-65. 2012
    ..Our efficient implementation makes this approach practical. We recommend its use in lieu of the less accurate approach in the conventional group analysis...
  8. pmc Mesolimbic recruitment by nondrug rewards in detoxified alcoholics: effort anticipation, reward anticipation, and reward delivery
    James M Bjork
    Division of Clinical Neuroscience and Behavioral Research, National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD 20892, USA
    Hum Brain Mapp 33:2174-88. 2012
    ....
  9. pmc Amygdala and ventrolateral prefrontal cortex function during anticipated peer evaluation in pediatric social anxiety
    Amanda E Guyer
    Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, 15K North Dr, Room 208, Bethesda, MD 20892 2670, USA
    Arch Gen Psychiatry 65:1303-12. 2008
    ..Such fear-circuitry dysfunction may also manifest when anticipated social evaluation leads socially anxious adolescents to misperceive peers as threatening...
  10. pmc Incentive-elicited mesolimbic activation and externalizing symptomatology in adolescents
    James M Bjork
    Division of Clinical Neuroscience and Behavioral Research, National Institute on Drug Abuse, National Institutes of Health NIH, Bethesda, MD 20892, USA
    J Child Psychol Psychiatry 51:827-37. 2010
    ..Reward processing has been indexed by recruitment of incentive-motivational neurocircuitry of the ventral striatum (VS), including nucleus accumbens (NAcc)...
  11. pmc Psychopathic tendencies and mesolimbic recruitment by cues for instrumental and passively obtained rewards
    James M Bjork
    Division of Clinical Neuroscience and Behavioral Research, National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD 20892, USA
    Biol Psychol 89:408-15. 2012
    ..These data indicate that in psychiatrically healthy controls, individuals with greater endorsement of psychopathic tendencies show more robust neurophysiological and behavioral signatures of incentive motivation...
  12. pmc Correcting brain-wide correlation differences in resting-state FMRI
    Ziad S Saad
    Scientific and Statistical Computing Core, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Brain Connect 3:339-52. 2013
    ..We find that, while GCOR reduced correlation differences between high and low movers, it is doubtful that motion was the sole driver behind the differences in the first place...
  13. pmc Training-associated changes and stability of attention bias in youth: Implications for Attention Bias Modification Treatment for pediatric anxiety
    Jennifer C Britton
    Section on Development and Affective Neuroscience, National Institute of Mental Health NIMH, 9000 Rockville Pike, Building 15K, Bethesda, MD 20892, USA
    Dev Cogn Neurosci 4:52-64. 2013
    ..Together, these two studies investigate the ways in which attention-bias stability may impact future work on ABMT...
  14. pmc Adolescents, adults and rewards: comparing motivational neurocircuitry recruitment using fMRI
    James M Bjork
    Division of Clinical Neuroscience and Behavioral Research, National Institute on Drug Abuse, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 5:e11440. 2010
    ....
  15. pmc Psychosocial problems and recruitment of incentive neurocircuitry: exploring individual differences in healthy adolescents
    James M Bjork
    Division of Clinical Neuroscience and Behavioral Research, National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD 20892, USA
    Dev Cogn Neurosci 1:570-77. 2011
    ..These findings extend previous reports demonstrating that in adolescents, individual differences in reactivity of motivational neurocircuitry relate to different facets of impulsivity or externalizing behaviors...
  16. doi request reprint Association of Irritability and Anxiety With the Neural Mechanisms of Implicit Face Emotion Processing in Youths With Psychopathology
    Joel Stoddard
    Division of Child and Adolescent Psychiatry, Department of Psychiatry, University of Colorado, Anshutz Medical Campus, Aurora2Section on Bipolar Spectrum Disorders, Emotion and Development Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland
    JAMA Psychiatry . 2016
    ..To our knowledge, few studies have simultaneously assessed the effect of 2 continuously distributed traits on brain-behavior relationships in children with psychopathology...
  17. pmc Developmental differences in the neural mechanisms of facial emotion labeling
    Jillian Lee Wiggins
    Emotion and Development Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Soc Cogn Affect Neurosci 11:172-81. 2016
    ..Charting the typical developmental course of the brain mechanisms of socioemotional processes, such as facial emotion labeling, is an important focus for developmental psychopathology research. ..
  18. pmc Neural response to self- and other referential praise and criticism in generalized social phobia
    Karina Blair
    Mood and Anxiety Program, National Institute of Mental Health, 15K North Dr, MSC 2670, Bethesda, MD 20892, USA
    Arch Gen Psychiatry 65:1176-84. 2008
    ..However, studies have not examined the neural response in GSP to another equally important class of social stimuli, the communication of praise or criticism...
  19. pmc Adapting to dynamic stimulus-response values: differential contributions of inferior frontal, dorsomedial, and dorsolateral regions of prefrontal cortex to decision making
    Derek G V Mitchell
    National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    J Neurosci 29:10827-34. 2009
    ..These data are interpreted with reference to models of dmPFC, dlPFC, and IFG functioning...
  20. pmc A new method for improving functional-to-structural MRI alignment using local Pearson correlation
    Ziad S Saad
    Department of Health and Human Services, Scientific and Statistical Computing Core, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 1148 USA
    Neuroimage 44:839-48. 2009
    ..Lastly, we emphasize the importance of precise visual inspection of alignment quality and present an automated method for generating composite images that help capture errors of misalignment...
  21. pmc Failing compensatory mechanisms during working memory in older apolipoprotein E-epsilon4 healthy adults
    Francesca M Filbey
    Geriatric Psychiatry Branch, NIMH, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Brain Imaging Behav 4:177-88. 2010
    ..This effect, however, appears to diminish with age...
  22. pmc Age-related differences in the neural correlates of trial-to-trial variations of reaction time
    Nancy E Adleman
    Department of Psychology, The Catholic University of America, 620 Michigan Ave, NE, Washington, DC 20064, USA Emotion and Development Branch, National Institute of Mental Health, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA Electronic address
    Dev Cogn Neurosci 19:248-57. 2016
    ..Critically for present purposes, all RT-BOLD relationships increased with age. Thus, RT-BOLD relationships may reflect robust, measurable changes in the brain-behavior relationship across development. ..
  23. ncbi request reprint Functional imaging analysis contest (FIAC) analysis according to AFNI and SUMA
    Ziad S Saad
    Scientific and Statistical Computing Core, National Institute of Mental Health, NIH, Department of Health and Human Services, Bethesda, Maryland 20892 1148, USA
    Hum Brain Mapp 27:417-24. 2006
    ..Sentence by speaker interaction effects were found in bilateral middle temporal gyrus, left inferior frontal, and left inferior temporal gyrus...
  24. pmc Trouble at rest: how correlation patterns and group differences become distorted after global signal regression
    Ziad S Saad
    Scientific and Statistical Computing Core, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    Brain Connect 2:25-32. 2012
    ..We touch on the need for careful accounting of nuisance parameters when making group comparisons of correlation maps...
  25. pmc Contextual fear conditioning in humans: cortical-hippocampal and amygdala contributions
    Ruben P Alvarez
    Mood and Anxiety Disorders Program, National Institute of Mental Health National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 28:6211-9. 2008
    ..These results provide evidence that similar brain mechanisms may underlie contextual fear conditioning across species...
  26. pmc Functional connectivity and laterality of the motor and sensory components in the volitional swallowing network
    Soren Y Lowell
    Laryngeal and Speech Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Building 10, 5D 38, 10 Center Drive, MSC 1416, Bethesda, MD 20892 1416, USA
    Exp Brain Res 219:85-96. 2012
    ..19). The greater connectivity from the left hemisphere insula to brain regions within and across hemispheres suggests that the insula is a primary integrative region for volitional swallowing in humans...
  27. pmc Phasic and sustained fear in humans elicits distinct patterns of brain activity
    Ruben P Alvarez
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
    Neuroimage 55:389-400. 2011
    ....
  28. pmc Neural circuitry of masked emotional face processing in youth with bipolar disorder, severe mood dysregulation, and healthy volunteers
    LAURA A THOMAS
    Emotion and Development Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, United States Office of the Director, National Institute on Drug Abuse, Bethesda, MD, United States Electronic address
    Dev Cogn Neurosci 8:110-20. 2014
    ..Regardless of awareness, BD and SMD differ in activation patterns from HV and each other in multiple brain regions, suggesting that BD and SMD are distinct developmental mood disorders...
  29. pmc Dietary tyrosine/phenylalanine depletion effects on behavioral and brain signatures of human motivational processing
    James M Bjork
    Division of Clinical Neuroscience and Behavioral Research, National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD, USA
    Neuropsychopharmacology 39:595-604. 2014
    ..Additional studies are needed to determine if clinical populations would show similar resistance to behavioral effects of TPD. ..
  30. pmc Abnormal ventromedial prefrontal cortex function in children with psychopathic traits during reversal learning
    Elizabeth C Finger
    National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    Arch Gen Psychiatry 65:586-94. 2008
    ....