Pavan P Adiseshaiah

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity
    Stephan T Stern
    Nanotechnology Characterization Laboratory, Advanced Technology Program, SAIC Frederick, Inc, NCI Frederick, Frederick, MD 21702, USA
    Part Fibre Toxicol 9:20. 2012
  2. doi request reprint Nanomaterial standards for efficacy and toxicity assessment
    Pavan P Adiseshaiah
    Nanotechnology Characterization Laboratory, Advanced Technology Program, SAIC Frederick, National Cancer Institute at Frederick, Frederick, MD 21702, USA
    Wiley Interdiscip Rev Nanomed Nanobiotechnol 2:99-112. 2010
  3. pmc Synergistic combination therapy with nanoliposomal C6-ceramide and vinblastine is associated with autophagy dysfunction in hepatocarcinoma and colorectal cancer models
    Pavan P Adiseshaiah
    Nanotechnology Characterization Laboratory, Advanced Technology Program, SAIC Frederick, Inc, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, United States
    Cancer Lett 337:254-65. 2013
  4. doi request reprint Nanomedicine strategies to overcome the pathophysiological barriers of pancreatic cancer
    Pavan P Adiseshaiah
    Nanotechnology Characterization Laboratory, Cancer Research Technology Program, Leidos Biomedical Research, Inc, Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702, USA
    Nat Rev Clin Oncol 13:750-765. 2016
  5. pmc Common pitfalls in nanotechnology: lessons learned from NCI's Nanotechnology Characterization Laboratory
    Rachael M Crist
    Nanotechnology Characterization Laboratory, Advanced Technology Program, SAIC Frederick, Inc, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA
    Integr Biol (Camb) 5:66-73. 2013

Collaborators

Detail Information

Publications6

  1. pmc Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity
    Stephan T Stern
    Nanotechnology Characterization Laboratory, Advanced Technology Program, SAIC Frederick, Inc, NCI Frederick, Frederick, MD 21702, USA
    Part Fibre Toxicol 9:20. 2012
    ..Indeed, there is ample evidence that biopersistent nanomaterials can cause autophagy and lysosomal dysfunctions resulting in toxicological consequences...
  2. doi request reprint Nanomaterial standards for efficacy and toxicity assessment
    Pavan P Adiseshaiah
    Nanotechnology Characterization Laboratory, Advanced Technology Program, SAIC Frederick, National Cancer Institute at Frederick, Frederick, MD 21702, USA
    Wiley Interdiscip Rev Nanomed Nanobiotechnol 2:99-112. 2010
    ..Finally, we show how knowledge of these properties (both of the nanoparticle and the cancer/tumor under study) can be used to design meaningful in vivo tests to evaluate nanoparticle efficacy...
  3. pmc Synergistic combination therapy with nanoliposomal C6-ceramide and vinblastine is associated with autophagy dysfunction in hepatocarcinoma and colorectal cancer models
    Pavan P Adiseshaiah
    Nanotechnology Characterization Laboratory, Advanced Technology Program, SAIC Frederick, Inc, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, United States
    Cancer Lett 337:254-65. 2013
    ..In conclusion, in vitro and in vivo data support a synergistic antitumor activity of the nanoliposomal C6-ceramide and vinblastine combination, potentially mediated by an autophagy mechanism. ..
  4. doi request reprint Nanomedicine strategies to overcome the pathophysiological barriers of pancreatic cancer
    Pavan P Adiseshaiah
    Nanotechnology Characterization Laboratory, Cancer Research Technology Program, Leidos Biomedical Research, Inc, Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702, USA
    Nat Rev Clin Oncol 13:750-765. 2016
    ..We discuss the approaches to nanomedicine that have been pursued to date and those that are the focus of ongoing research, and outline their potential, as well as the key challenges that must be overcome...
  5. pmc Common pitfalls in nanotechnology: lessons learned from NCI's Nanotechnology Characterization Laboratory
    Rachael M Crist
    Nanotechnology Characterization Laboratory, Advanced Technology Program, SAIC Frederick, Inc, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA
    Integr Biol (Camb) 5:66-73. 2013
    ..While not exhaustive, this article aims to share some of the most common pitfalls observed by the NCL as they relate to nanoparticle synthesis, purification, characterization and analysis...