- Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutationsA M Cataldo
Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
Am J Pathol 157:277-86. 2000....
- The endosomal-lysosomal system of neurons in Alzheimer's disease pathogenesis: a reviewR A Nixon
Center for Dementia Research, Nathan Kline Institute, Orangeburg, New York 10962, USA
Neurochem Res 25:1161-72. 2000..These and other studies support the view that the progressive alterations of lysosomal function observed during aging and Alzheimer's disease contribute importantly to the neurodegenerative process in Alzheimer's disease...