Elena Zaslavsky

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. pmc Reconstruction of regulatory networks through temporal enrichment profiling and its application to H1N1 influenza viral infection
    Elena Zaslavsky
    Center for Translational Systems Biology and Department of Neurology, Mount Sinai School of Medicine, New York, NY 10029, USA
    BMC Bioinformatics 14:S1. 2013
  2. pmc Antiviral response dictated by choreographed cascade of transcription factors
    Elena Zaslavsky
    Center for Translational Systems Biology, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Immunol 184:2908-17. 2010
  3. pmc Human Dendritic Cell Response Signatures Distinguish 1918, Pandemic, and Seasonal H1N1 Influenza Viruses
    Boris M Hartmann
    Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, New York, USA Center for Translational Systems Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA
    J Virol 89:10190-205. 2015
  4. pmc Computational approaches to understanding dendritic cell responses to influenza virus infection
    Elena Zaslavsky
    Department of Neurology and Center for Translational Systems Biology, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029 6574, USA
    Immunol Res 54:160-8. 2012
  5. pmc CellCODE: a robust latent variable approach to differential expression analysis for heterogeneous cell populations
    Maria Chikina
    Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA 15217, USA and Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
    Bioinformatics 31:1584-91. 2015
  6. pmc β-catenin regulates GnRH-induced FSHβ gene expression
    Qian Wang
    Department of Neurology, Center for Translational Systems Biology, Mount Sinai School of Medicine, New York, New York 10029, USA
    Mol Endocrinol 27:224-37. 2013

Collaborators

Detail Information

Publications6

  1. pmc Reconstruction of regulatory networks through temporal enrichment profiling and its application to H1N1 influenza viral infection
    Elena Zaslavsky
    Center for Translational Systems Biology and Department of Neurology, Mount Sinai School of Medicine, New York, NY 10029, USA
    BMC Bioinformatics 14:S1. 2013
    ..Identifying the underlying transcriptional network driving these changes, and how this program is altered by virally-encoded immune antagonists, is a fundamental challenge in systems immunology...
  2. pmc Antiviral response dictated by choreographed cascade of transcription factors
    Elena Zaslavsky
    Center for Translational Systems Biology, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Immunol 184:2908-17. 2010
    ..More generally, our results show how a genetic program can be temporally controlled through a single regulatory network to achieve the large-scale genetic reprogramming characteristic of cell-state transitions...
  3. pmc Human Dendritic Cell Response Signatures Distinguish 1918, Pandemic, and Seasonal H1N1 Influenza Viruses
    Boris M Hartmann
    Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, New York, USA Center for Translational Systems Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA
    J Virol 89:10190-205. 2015
    ..Comparison of the global responses to the seasonal and pandemic strains showed that a dramatic divergence occurred after 4 h, with only the seasonal strains inducing widespread mRNA loss...
  4. pmc Computational approaches to understanding dendritic cell responses to influenza virus infection
    Elena Zaslavsky
    Department of Neurology and Center for Translational Systems Biology, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029 6574, USA
    Immunol Res 54:160-8. 2012
    ..Our tools, models, and data can be accessed at http://tsb.mssm.edu/primeportal/ ...
  5. pmc CellCODE: a robust latent variable approach to differential expression analysis for heterogeneous cell populations
    Maria Chikina
    Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA 15217, USA and Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
    Bioinformatics 31:1584-91. 2015
    ..However, there is no method that comprehensively addresses mixture analysis in the context of differential expression without relying on additional proportion information, which can be inaccurate and is frequently unavailable...
  6. pmc β-catenin regulates GnRH-induced FSHβ gene expression
    Qian Wang
    Department of Neurology, Center for Translational Systems Biology, Mount Sinai School of Medicine, New York, New York 10029, USA
    Mol Endocrinol 27:224-37. 2013
    ..Furthermore, knockdown of Brms1L significantly attenuated GnRH-induced FSHβ expression. Thus, our findings indicate that the expression of Brms1L depends on β-catenin activity and contributes to FSHβ induction by GnRH...