Jaclyn F Hechtman

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. doi Intramuscular corpora amylacea adjacent to ileal low-grade neuroendocrine tumours (typical carcinoids): a light microscopic, immunohistochemical and ultrastructural study
    Jaclyn Frances Hechtman
    Department of Pathology, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Clin Pathol 66:569-72. 2013
  2. doi Promyelocytic leukemia zinc finger and histone H1.5 differentially stain low- and high-grade pulmonary neuroendocrine tumors: a pilot immunohistochemical study
    Jaclyn Frances Hechtman
    Department of Pathology, Mount Sinai School of Medicine and Medical Center, New York, NY 10029, USA
    Hum Pathol 44:1400-5. 2013
  3. doi Intraductal polypoid lipid-rich neuroendocrine tumor of the pancreas with entrapped ductules: case report and review of the literature
    Jaclyn Frances Hechtman
    Department of Pathology, Mount Sinai School of Medicine, One Gustave L Levy Place, 1194, New York, NY 10029, USA
    Endocr Pathol 24:30-5. 2013
  4. doi Thymomas diagnosed during pregnancy: two cases in young women without paraneoplastic or autoimmune disease
    Jaclyn F Hechtman
    Department of Pathology, Mount Sinai School of Medicine, New York, NY, USA
    Ann Diagn Pathol 16:392-6. 2012
  5. pmc Anti-glutamate receptor 2 as a new potential diagnostic probe for prostatic adenocarcinoma: a pilot immunohistochemical study
    Jaclyn F Hechtman
    Department of Pathology, Mount Sinai School of Medicine, New York, NY, USA
    Appl Immunohistochem Mol Morphol 20:344-9. 2012
  6. doi HER2/neu gene amplification and protein overexpression in gastric and gastroesophageal junction adenocarcinoma: a review of histopathology, diagnostic testing, and clinical implications
    Jaclyn F Hechtman
    Department of Pathology, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Arch Pathol Lab Med 136:691-7. 2012
  7. doi Hepatocellular carcinoma arising in a pigmented telangiectatic adenoma with nuclear β-catenin and glutamine synthetase positivity: case report and review of the literature
    Jaclyn F Hechtman
    Department of Pathology, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Am J Surg Pathol 35:927-32. 2011
  8. doi Ischemic bowel due to embolization from an isolated mobile thrombus of the ascending aorta: a case report and review of the literature
    Jaclyn F Hechtman
    Department of Pathology, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    J Thromb Thrombolysis 32:238-41. 2011
  9. pmc Recurrent, truncating SOX9 mutations are associated with SOX9 overexpression, KRAS mutation, and TP53 wild type status in colorectal carcinoma
    Breanna M Javier
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Oncotarget 7:50875-50882. 2016
  10. pmc ARID1A expression in early stage colorectal adenocarcinoma: an exploration of its prognostic significance
    Lik Hang Lee
    Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY, 10065 Electronic address
    Hum Pathol 53:97-104. 2016

Collaborators

Detail Information

Publications19

  1. doi Intramuscular corpora amylacea adjacent to ileal low-grade neuroendocrine tumours (typical carcinoids): a light microscopic, immunohistochemical and ultrastructural study
    Jaclyn Frances Hechtman
    Department of Pathology, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Clin Pathol 66:569-72. 2013
    ....
  2. doi Promyelocytic leukemia zinc finger and histone H1.5 differentially stain low- and high-grade pulmonary neuroendocrine tumors: a pilot immunohistochemical study
    Jaclyn Frances Hechtman
    Department of Pathology, Mount Sinai School of Medicine and Medical Center, New York, NY 10029, USA
    Hum Pathol 44:1400-5. 2013
    ..5 may correlate with grade of pulmonary neuroendocrine tumors. Immunohistochemical stains for these markers, especially on small biopsies with crush artifact, may prove to be diagnostically useful...
  3. doi Intraductal polypoid lipid-rich neuroendocrine tumor of the pancreas with entrapped ductules: case report and review of the literature
    Jaclyn Frances Hechtman
    Department of Pathology, Mount Sinai School of Medicine, One Gustave L Levy Place, 1194, New York, NY 10029, USA
    Endocr Pathol 24:30-5. 2013
    ..The literature pertaining to the unique features of this case is reviewed including clinical and pathologic pitfalls and the possible etiologic and prognostic significance of these findings...
  4. doi Thymomas diagnosed during pregnancy: two cases in young women without paraneoplastic or autoimmune disease
    Jaclyn F Hechtman
    Department of Pathology, Mount Sinai School of Medicine, New York, NY, USA
    Ann Diagn Pathol 16:392-6. 2012
    ....
  5. pmc Anti-glutamate receptor 2 as a new potential diagnostic probe for prostatic adenocarcinoma: a pilot immunohistochemical study
    Jaclyn F Hechtman
    Department of Pathology, Mount Sinai School of Medicine, New York, NY, USA
    Appl Immunohistochem Mol Morphol 20:344-9. 2012
    ..In conclusion, our preliminary data demonstrated potential utility of 6C4 in the pathologic evaluation of PC...
  6. doi HER2/neu gene amplification and protein overexpression in gastric and gastroesophageal junction adenocarcinoma: a review of histopathology, diagnostic testing, and clinical implications
    Jaclyn F Hechtman
    Department of Pathology, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Arch Pathol Lab Med 136:691-7. 2012
    ..Here, we briefly review the molecular biology, histopathology, diagnostic techniques, and interpretation, as well as the clinical implications, of HER2 amplification/overexpression in gastric and gastroesophageal adenocarcinoma...
  7. doi Hepatocellular carcinoma arising in a pigmented telangiectatic adenoma with nuclear β-catenin and glutamine synthetase positivity: case report and review of the literature
    Jaclyn F Hechtman
    Department of Pathology, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Am J Surg Pathol 35:927-32. 2011
    ....
  8. doi Ischemic bowel due to embolization from an isolated mobile thrombus of the ascending aorta: a case report and review of the literature
    Jaclyn F Hechtman
    Department of Pathology, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    J Thromb Thrombolysis 32:238-41. 2011
    ..Work-up for patients presenting with signs of peripheral embolization, or in this case, necrotic bowel, should include the aorta as a source of embolic thrombi...
  9. pmc Recurrent, truncating SOX9 mutations are associated with SOX9 overexpression, KRAS mutation, and TP53 wild type status in colorectal carcinoma
    Breanna M Javier
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Oncotarget 7:50875-50882. 2016
    ..We aimed to clarify the effect of SOX9 mutations on SOX9 protein expression and their association with known molecular subtypes and clinical characteristics in advanced CRC...
  10. pmc ARID1A expression in early stage colorectal adenocarcinoma: an exploration of its prognostic significance
    Lik Hang Lee
    Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY, 10065 Electronic address
    Hum Pathol 53:97-104. 2016
    ..Such data are clinically relevant, as efforts are ongoing in identifying markers that can detect the small but significant subset of early stage CRCs that will have a poor outcome. ..
  11. pmc Morphological characterization of colorectal cancers in The Cancer Genome Atlas reveals distinct morphology-molecular associations: clinical and biological implications
    Jinru Shia
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Mod Pathol . 2016
    ..Modern Pathology advance online publication, 16 December 2016; doi:10.1038/modpathol.2016.198...
  12. pmc Identification of Targetable Kinase Alterations in Patients with Colorectal Carcinoma That are Preferentially Associated with Wild-Type RAS/RAF
    Jaclyn F Hechtman
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York
    Mol Cancer Res 14:296-301. 2016
    ..Larger studies are warranted to further define these kinase alterations as novel therapeutic targets in colorectal carcinoma and as negative predictors of response to anti-EGFR therapy...
  13. pmc Outcomes following resection of intrahepatic cholangiocarcinoma
    Parissa Tabrizian
    Department of Surgery, Division of Surgical Oncology, Mount Sinai Medical Center, New York, NY, USA
    HPB (Oxford) 17:344-51. 2015
    ..The aim of this analysis was to examine prognostic features and outcomes in patients undergoing resection for intrahepatic cholangiocarcinoma (ICC)...
  14. pmc A Novel Crizotinib-Resistant Solvent-Front Mutation Responsive to Cabozantinib Therapy in a Patient with ROS1-Rearranged Lung Cancer
    Alexander Drilon
    Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York Weill Cornell Medical College, New York, New York
    Clin Cancer Res 22:2351-8. 2016
    ..The development of acquired resistance, however, poses a serious clinical challenge. Consequently, experimental and clinical validation of resistance mechanisms and potential second-line therapies is essential...
  15. pmc Patterns and prognostic relevance of PD-1 and PD-L1 expression in colorectal carcinoma
    Lik Hang Lee
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Mod Pathol 29:1433-1442. 2016
    ....
  16. pmc Next-Generation Assessment of ERBB2 (Human Epidermal Growth Factor Receptor 2) Amplification Status: Clinical Validation in the Context of a Hybrid Capture-Based, Comprehensive Solid Tumor Genomic Profiling Assay
    Dara S Ross
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York Electronic address
    J Mol Diagn . 2016
    ..ERBB2 amplification status can be reliably determined by hybridization capture-based NGS methods, allowing efficient concurrent testing for other potentially actionable genomic alterations, particularly in limited material...
  17. doi Carcinoma ex microcystic adenoma of the pancreas: a report of a novel form of malignancy in serous neoplasms
    Hongfa Zhu
    Department of Pathology, The Mount Sinai Medical Center, New York, NY 10029, USA
    Am J Surg Pathol 36:305-10. 2012
    ..We believe that this case represents the first case of a cytologically malignant neoplasm arising from a benign serous cystadenoma (carcinoma ex microcystic serous cystadenoma)...
  18. pmc Sequencing of 279 cancer genes in ampullary carcinoma reveals trends relating to histologic subtypes and frequent amplification and overexpression of ERBB2 (HER2)
    Jaclyn F Hechtman
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Mod Pathol 28:1123-9. 2015
    ....
  19. doi Neurogenic polyps of the gastrointestinal tract: a clinicopathologic review with emphasis on differential diagnosis and syndromic associations
    Jaclyn F Hechtman
    From the Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York Dr Hechtman and the Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, New York Dr Harpaz
    Arch Pathol Lab Med 139:133-9. 2015
    ..We review the pathology of these polyps with an emphasis on the diagnostic challenges that they pose and on newly described subtypes. ..