Janine D Flory
Affiliation: Mount Sinai School of Medicine
- Irritable assault and variation in the COMT geneJanine D Flory
Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, USA
Psychiatr Genet 17:344-6. 2007..These findings provide limited support for a role of COMT in modulating aggressive behavior, and are extended to people with personality disorders...
- Catechol-O-methyltransferase Val158Met genotype variation is associated with prefrontal-dependent task performance in schizotypal personality disorder patients and comparison groupsMichael J Minzenberg
Bronx Veterans Affairs Medical Center, Bronx, New York, 14068, USA
Psychiatr Genet 16:117-24. 2006..We evaluated the relationship of the COMT genotype with diagnostic status and cognitive performance in schizotypal personality disorder...
- Dispositional impulsivity in normal and abnormal samplesJanine D Flory
Department of Psychiatry, Box 1230, One Gustave Levy Place, Mount Sinai School of Medicine, New York, NY 10029, United States
J Psychiatr Res 40:438-47. 2006..Results from these analyses also lend support to a large body of work that demonstrates that normal and abnormal personality features are related...
- Alcohol dependence, disinhibited behavior and variation in the prodynorphin geneJanine D Flory
Department of Psychology, Queens College and The Graduate Center, City University of New York, New York, NY, USA
Biol Psychol 88:51-6. 2011..g., drug use, sexual activity)...
- Preference for immediate over delayed rewards is associated with magnitude of ventral striatal activityAhmad R Hariri
Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
J Neurosci 26:13213-7. 2006..They also highlight a specific neurocognitive mechanism that may contribute to increased risk for addiction...
- Sexual dysfunction and neuroendocrine correlates of posttraumatic stress disorder in combat veterans: Preliminary findingsAmy Lehrner
James J Peters Veterans Affairs Medical Center, Mental Health Patient Care Center, Bronx, NY, USA Icahn School of Medicine at Mount Sinai, Department of Psychiatry, New York, NY, USA Electronic address
Psychoneuroendocrinology 63:271-5. 2016..More detailed assessment of sexual dysfunction in biologically informed studies of PTSD is warranted to clarify the relationships of PTSD symptomatology and related neurobiology with sexual dysfunction. ..
- Perigenual anterior cingulate morphology covaries with perceived social standingPeter J Gianaros
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
Soc Cogn Affect Neurosci 2:161-73. 2007..The pACC may represent a neuroanatomical substrate by which perceived social standing relates to mental and physical health...
- Trait negative affect: toward an integrated model of understanding psychological risk for impairment in cardiac autonomic functionMaria E Bleil
Department of Psychiatry, University of California San Francisco, 3333 California Street, Suite 465, San Francisco, CA 94143 0848, USA
Psychosom Med 70:328-37. 2008..g., autonomic nervous system [ANS] dysfunction), the degree to which a general tendency to experience negative emotions may account for these relations is not known...
- Neural basis of individual differences in impulsivity: contributions of corticolimbic circuits for behavioral arousal and controlSarah M Brown
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
Emotion 6:239-45. 2006..Together, these findings suggest that dispositional impulsivity is influenced by the functional interplay of corticolimbic behavioral arousal and control circuits...
- WITHDRAWN: Precuneal and amygdala spontaneous activity and functional connectivity in war-zone-related PTSDXiaodan Yan
Steven and Alexandra Cohen Veterans Center for the Study of Posttraumatic Stress and Traumatic Brain Injury, Department of Psychiatry, NYU School of Medicine, New York, NY, USA Electronic address
Psychiatry Res . 2014..This article has been withdrawn at the request of the author. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy...
- OXTR polymorphism predicts social relationships through its effects on social temperamentKasey G Creswell
Department of Psychology, Carnegie Mellon University, Department of Psychology, University of Pittsburgh, Behavioral and Policy Sciences, RAND Corporation, Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA, USA, Department of Psychiatry, Mount Sinai School of Medicine, and James J Peters VAMC, New York, NY, USA
Soc Cogn Affect Neurosci 10:869-76. 2015..Results replicated in the African American sample. Findings suggest that OXTR variation modulates levels of social support via proximal impacts on individual temperament. ..
- Self-reported sleep duration is associated with the metabolic syndrome in midlife adultsMartica H Hall
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Sleep 31:635-43. 2008..In the present study, we evaluated the relationship between sleep duration and presence of the metabolic syndrome, which is a cluster of physiologically interrelated risk factors for cardiometabolic disease...
- Neurobiologic function and temperament in subjects with personality disordersVivian Mitropoulou
Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, USA
CNS Spectr 8:725-30. 2003....
- Comorbidity between post-traumatic stress disorder and major depressive disorder: alternative explanations and treatment considerationsJanine D Flory
James J Peters Veterans Affairs Medical Center, Bronx, USA Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, USA
Dialogues Clin Neurosci 17:141-50. 2015..Support for the latter explanation is inferred from literature that examines risk and biological correlates of PTSD and MDD, including molecular processes. Treatment implications of the comorbidity are considered. ..
- Cortisol augmentation of a psychological treatment for warfighters with posttraumatic stress disorder: Randomized trial showing improved treatment retention and outcomeRachel Yehuda
James J Peters Veterans Affairs Medical Center, Bronx, New York, United States Traumatic Stress Studies Division, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States Electronic address
Psychoneuroendocrinology 51:589-97. 2015..We also hypothesized that in responders, hydrocortisone augmentation would be more effective in reversing glucocorticoid indices associated with PTSD than placebo augmentation...
- The use of biomarkers in the military: from theory to practiceRachel Yehuda
Department of Psychiatry, James J Peters Veterans Affairs Medical Center, Bronx, NY, United States Department of Psychiatry and Neuroscience, Mount Sinai School of Medicine, New York, NY, United States Electronic address
Psychoneuroendocrinology 38:1912-22. 2013....
- Joint Effect of Childhood Abuse and Family History of Major Depressive Disorder on Rates of PTSD in People with Personality DisordersJanine D Flory
Department of Psychiatry, Mount Sinai School of Medicine MSSM, One Gustave L Levy Place, NY 10029, USA
Depress Res Treat 2012:350461. 2012....
- COMT val158Met and executive control: a test of the benefit of specific deficits to translational researchAngus W MacDonald
Department of Psychology, University of Pittsburgh, USA
J Abnorm Psychol 116:306-12. 2007..These data suggest that the interpretability gained by including task manipulations to uncover specific deficits can enhance associations between cognitive and genetic levels of analysis...
- Human choline transporter gene variation is associated with corticolimbic reactivity and autonomic-cholinergic functionSerina A Neumann
Department of Psychiatry and Behavioral Sciences, Eastern Virginia Medical School, 825 Fairfax Avenue, Norfolk, VA 23501
Biol Psychiatry 60:1155-62. 2006..Here, functional magnetic resonance imaging (fMRI) was used to examine the relation between a single nucleotide polymorphism (SNP) in CHT1 on regional brain reactivity relevant to autonomic (cholinergic) function...
- Context processing in schizotypal personality disorder: evidence of specificity of impairment to the schizophrenia spectrumMargaret M McClure
VA VISN 3 Mental Illness Research, Education and Clinical Center, Bronx, New York 10468, USA
J Abnorm Psychol 117:342-54. 2008..These findings, which are quite similar to those previously reported in patients with schizophrenia, suggest that context processing deficits are specific to the schizophrenia spectrum and are not a reflection of overall psychopathology...
- Socio-economic status covaries with central nervous system serotonergic responsivity as a function of allelic variation in the serotonin transporter gene-linked polymorphic regionStephen B Manuck
Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh, 506 EH, 4015 O Hara Street, Pittsburgh, PA 15260, USA
Psychoneuroendocrinology 29:651-68. 2004..We conclude that allelic variation at 5-HTTLPR moderates the influence of social position on CNS serotonergic responsivity...
- The socio-economic status of communities predicts variation in brain serotonergic responsivityStephen B Manuck
Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh, PA 15260, USA
Psychol Med 35:519-28. 2005..Here we examine whether serotonergic responsivity covaries similarly with the SES of communities, as indexed by US Census data in the same study sample...
- Serotonergic function in children with attention-deficit hyperactivity disorder: relationship to later antisocial personality disorderJanine D Flory
Department of Psychology, Queens College, City University of New York, 65 30 Kissena Boulevard, SB 318 Flushing, NY 11367, USA
Br J Psychiatry 190:410-4. 2007..Impulsive aggression in adulthood is associated with disturbances in serotonergic function. In contrast, research examining this association in childhood has yielded inconsistent results...
- Central nervous system serotonergic responsivity and aggressive disposition in menStephen B Manuck
Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh, PA, USA
Physiol Behav 77:705-9. 2002..This finding suggests that association of the MAO-A promoter polymorphism with this behavioral phenotype may be mediated, in part, by allele-specific variation in central serotonergic responsivity...