Affiliation: Mount Sinai School of Medicine
- Processing of Bacillus subtilis small cytoplasmic RNA: evidence for an additional endonuclease cleavage siteShiyi Yao
Mount Sinai School of Medicine of New York University, New York, NY 10029, USA
Nucleic Acids Res 35:4464-73. 2007..RNase J1 is responsible for much of the cleavage that releases scRNA from downstream sequences. The subsequent exonucleolytic processing is carried out largely by RNase PH...
- Bacillus subtilis mRNA decay: new parts in the toolkitDavid H Bechhofer
Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY, USA
Wiley Interdiscip Rev RNA 2:387-94. 2011..The presence of these ribonucleases in B. subtilis predicts significant differences from the well-established model of mRNA decay in Escherichia coli...
- Decay of a model mRNA in Bacillus subtilis by a combination of RNase J1 5' exonuclease and RNase Y endonuclease activitiesShiyi Yao
Department of Pharmacology and Systems Therapeutics, Box 1603, Mount Sinai School of Medicine, New York, NY 10029, USA
J Bacteriol 193:6384-6. 2011..Evidence is presented that both of these activities determine the half-life of ΔermC mRNA...
- INITIATION OF MRNA DECAY IN BACILLUS SUBTILISDavid H Bechhofer; Fiscal Year: 2010..Elucidating the mechanism of mRNA in this bacterium could lead to the design of new antibiotics that inhibit the mRNA decay process and thereby prevent successful bacterial colonization of human tissues. ..