Kevin J Mortimer
- Oral and inhaled corticosteroids and adrenal insufficiency: a case-control studyK J Mortimer
Division of Respiratory Medicine, Nottingham City Hospital, Nottingham NG5 1PB, UK
Thorax 61:405-8. 2006..A study was undertaken to quantify the association between adrenal insufficiency and oral and inhaled corticosteroid exposure...
- Plasma concentrations of inhaled corticosteroids in relation to airflow obstruction in asthmaKevin J Mortimer
Division of Respiratory Medicine, Nottingham City Hospital, University of Nottingham, Nottingham, UK
Br J Clin Pharmacol 62:412-9. 2006..To compare the pharmacokinetic profiles of beclometasone, budesonide, fluticasone and mometasone following inhalation in patients with asthma, and explore the relationship between lung function and plasma drug concentrations...
- Plasma concentrations of fluticasone propionate and budesonide following inhalation: effect of induced bronchoconstrictionKevin J Mortimer
Division of Respiratory Medicine, University of Nottingham, UK
Br J Clin Pharmacol 64:439-44. 2007..To determine whether and to what extent bronchoconstriction affects plasma concentrations of fluticasone and budesonide following inhalation...
- Systemic and bronchodilator effects of inhaled rac-formoterol in subjects with chronic obstructive pulmonary disease: a dose-response studyChristopher I Whale
Division of Respiratory Medicine, University of Nottingham, City Hospital, Nottingham, UK
Br J Clin Pharmacol 65:841-7. 2008..There are concerns with the overall safety of high-dose beta(2)-agonists in subjects with COPD, and this study looks at the balance of beneficial and adverse effects of a range of doses of inhaled formoterol...
- Benefit versus risk for oral, inhaled, and nasal glucocorticosteroidsKevin J Mortimer
Division of Respiratory Medicine, Clinical Sciences Building, City Hospital, Hucknall Road, Nottingham NG5 1PB, UK
Immunol Allergy Clin North Am 25:523-39. 2005..This optimal dose needs to be determined on an individual basis and is likely to vary as disease severity changes over time...